Matthias Mann

299.1k total citations · 81 hit papers
845 papers, 215.4k citations indexed

About

Matthias Mann is a scholar working on Molecular Biology, Spectroscopy and Cell Biology. According to data from OpenAlex, Matthias Mann has authored 845 papers receiving a total of 215.4k indexed citations (citations by other indexed papers that have themselves been cited), including 640 papers in Molecular Biology, 375 papers in Spectroscopy and 94 papers in Cell Biology. Recurrent topics in Matthias Mann's work include Advanced Proteomics Techniques and Applications (342 papers), Mass Spectrometry Techniques and Applications (239 papers) and Metabolomics and Mass Spectrometry Studies (105 papers). Matthias Mann is often cited by papers focused on Advanced Proteomics Techniques and Applications (342 papers), Mass Spectrometry Techniques and Applications (239 papers) and Metabolomics and Mass Spectrometry Studies (105 papers). Matthias Mann collaborates with scholars based in Germany, Denmark and United States. Matthias Mann's co-authors include Jürgen Cox, Matthias Wilm, Jesper V. Olsen, Andrej Shevchenko, Ruedi Aebersold, Nagarjuna Nagaraj, Jacek R. Wiśniewski, Juri Rappsilber, Ole Vorm and Yasushi Ishihama and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Matthias Mann

833 papers receiving 211.9k citations

Hit Papers

MaxQuant enables high peptide identificat... 1989 2026 2001 2013 2008 1996 2009 1989 2016 2.5k 5.0k 7.5k 10.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
    2008 11.1k citations Jürgen Cox, Matthias Mann profile →
  2. Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels
    1996 7.9k citations Matthias Mann et al. profile →
  3. Universal sample preparation method for proteome analysis
    2009 6.2k citations Jacek R. Wiśniewski, Nagarjuna Nagaraj et al. profile →
  4. Electrospray Ionization for Mass Spectrometry of Large Biomolecules
    1989 5.6k citations Matthias Mann et al. Science profile →
  5. The Perseus computational platform for comprehensive analysis of (prote)omics data
    2016 5.4k citations Stefka Tyanova, Marco Y. Hein et al. profile →
  6. Mass spectrometry-based proteomics
    2003 5.1k citations Matthias Mann et al. profile →
  7. Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics
    2002 4.4k citations Matthias Mann et al. profile →
  8. Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment
    2011 4.1k citations Jürgen Cox, Annette Michalski et al. Journal of Proteome Research profile →
  9. In-gel digestion for mass spectrometric characterization of proteins and proteomes
    2006 4.0k citations Jesper V. Olsen, Matthias Mann et al. profile →
  10. Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ
    2014 3.6k citations Jürgen Cox, Marco Y. Hein et al. profile →
  11. Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
    2009 3.3k citations Chunaram Choudhary, Chanchal Kumar et al. Science profile →
  12. Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips
    2007 3.2k citations Matthias Mann et al. profile →
  13. Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks
    2006 2.8k citations Jesper V. Olsen, Florian Gnad et al. profile →
  14. FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex
    1996 2.6k citations Matthias Mann et al. profile →
  15. A generic protein purification method for protein complex characterization and proteome exploration
    1999 2.2k citations Matthias Mann et al. profile →
  16. Stop and Go Extraction Tips for Matrix-Assisted Laser Desorption/Ionization, Nanoelectrospray, and LC/MS Sample Pretreatment in Proteomics
    2002 2.0k citations Matthias Mann et al. profile →
  17. IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation
    1997 1.8k citations Matthias Mann et al. Science profile →
  18. Exponentially Modified Protein Abundance Index (emPAI) for Estimation of Absolute Protein Amount in Proteomics by the Number of Sequenced Peptides per Protein
    2005 1.7k citations Matthias Mann et al. profile →
  19. Proteomics to study genes and genomes
    2000 1.7k citations Matthias Mann et al. profile →
  20. Proteomic analysis of post-translational modifications
    2003 1.6k citations Matthias Mann et al. profile →
  21. Mass-spectrometric exploration of proteome structure and function
    2016 1.5k citations Matthias Mann et al. profile →
  22. Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry
    1996 1.4k citations Matthias Mann et al. profile →
  23. Analytical Properties of the Nanoelectrospray Ion Source
    1996 1.4k citations Matthias Mann et al. profile →
  24. Parts per Million Mass Accuracy on an Orbitrap Mass Spectrometer via Lock Mass Injection into a C-trap
    2005 1.3k citations Jesper V. Olsen, Matthias Mann et al. profile →
  25. L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity
    2016 1.2k citations Felix Meissner, Matthias Mann et al. profile →
  26. Electrospray ionization–principles and practice
    1990 1.2k citations Matthias Mann et al. profile →
  27. Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells
    2014 1.2k citations Nagarjuna Nagaraj, Matthias Mann et al. profile →
  28. Linking genome and proteome by mass spectrometry: Large-scale identification of yeast proteins from two dimensional gels
    1996 1.2k citations Matthias Mann et al. Proceedings of the National Academy of Sciences profile →
  29. Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis
    2010 1.2k citations Jesper V. Olsen, Chanchal Kumar et al. profile →
  30. Mass spectrometry–based proteomics turns quantitative
    2005 1.2k citations Matthias Mann et al. Nature Chemical Biology profile →
  31. Error-Tolerant Identification of Peptides in Sequence Databases by Peptide Sequence Tags
    1994 1.2k citations Matthias Mann et al. profile →
  32. Proteomic characterization of the human centrosome by protein correlation profiling
    2003 1.1k citations Jens Andersen, Matthias Mann et al. profile →
  33. The growing landscape of lysine acetylation links metabolism and cell signalling
    2014 1.0k citations Chunaram Choudhary, Matthias Mann et al. profile →
  34. Reverse Transcriptase Motifs in the Catalytic Subunit of Telomerase
    1997 998 citations Matthias Mann et al. Science profile →
  35. Trypsin Cleaves Exclusively C-terminal to Arginine and Lysine Residues
    2004 947 citations Jesper V. Olsen, Matthias Mann et al. profile →
  36. Nucleolar proteome dynamics
    2005 946 citations Jens Andersen, Yun Wah Lam et al. profile →
  37. A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances
    2015 905 citations Marco Y. Hein, Jürgen Cox et al. profile →
  38. Glucosylation of Rho proteins by Clostridium difficile toxin B
    1995 872 citations Matthias Mann et al. profile →
  39. Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans
    2016 857 citations Matthias Mann et al. Nature Communications profile →
  40. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs
    2002 854 citations Matthias Mann et al. profile →
  41. Directed Proteomic Analysis of the Human Nucleolus
    2002 849 citations Jens Andersen, Yun Wah Lam et al. profile →
  42. Analysis of Proteins and Proteomes by Mass Spectrometry
    2001 843 citations Matthias Mann et al. profile →
  43. The abc's (and xyz's) of peptide sequencing
    2004 791 citations Matthias Mann et al. profile →
  44. The Exosome: A Conserved Eukaryotic RNA Processing Complex Containing Multiple 3′→5′ Exoribonucleases
    1997 781 citations Matthias Mann et al. profile →
  45. Deep proteome and transcriptome mapping of a human cancer cell line
    2011 781 citations Nagarjuna Nagaraj, Jacek R. Wiśniewski et al. profile →
  46. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
    2005 773 citations Matthias Mann et al. profile →
  47. Functional and quantitative proteomics using SILAC
    2006 753 citations Matthias Mann profile →
  48. Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling
    2014 750 citations Kirti Sharma, Stefka Tyanova et al. profile →
  49. Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome
    2002 750 citations Matthias Mann et al. profile →
  50. Higher-energy C-trap dissociation for peptide modification analysis
    2007 749 citations Jesper V. Olsen, Matthias Mann et al. profile →
  51. Precision Mapping of an In Vivo N-Glycoproteome Reveals Rigid Topological and Sequence Constraints
    2010 748 citations Dorota Zielińska, Florian Gnad et al. profile →
  52. Electrospray and Taylor-Cone theory, Dole's beam of macromolecules at last?
    1994 741 citations Matthias Mann et al. profile →
  53. A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles
    2011 735 citations Michael L. Nielsen, Jürgen Cox et al. profile →
  54. Large-Scale Proteomic Analysis of the Human Spliceosome
    2002 732 citations Angus I. Lamond, Matthias Mann et al. profile →
  55. Integrated Analysis of Protein Composition, Tissue Diversity, and Gene Regulation in Mouse Mitochondria
    2003 726 citations Vamsi K. Mootha, Jakob Bunkenborg et al. profile →
  56. AU Binding Proteins Recruit the Exosome to Degrade ARE-Containing mRNAs
    2001 720 citations Matthias Mann et al. profile →
  57. Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast
    2008 716 citations Jesper V. Olsen, Jürgen Cox et al. profile →
  58. From genomics to proteomics
    2003 712 citations Matthias Mann et al. profile →
  59. Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors
    2003 707 citations Matthias Mann et al. Proceedings of the National Academy of Sciences profile →
  60. Use of mass spectrometric molecular weight information to identify proteins in sequence databases
    1993 706 citations Matthias Mann et al. profile →
  61. Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases
    2016 705 citations Martin Steger, Francesca Tonelli et al. eLife profile →
  62. A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC)
    2006 692 citations Matthias Mann et al. profile →
  63. Selective Anchoring of TFIID to Nucleosomes by Trimethylation of Histone H3 Lysine 4
    2007 675 citations Matthias Mann et al. profile →
  64. Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
    2002 659 citations Matthias Mann et al. profile →
  65. Quantitative Phosphoproteomics Applied to the Yeast Pheromone Signaling Pathway
    2005 647 citations Jesper V. Olsen, Matthias Mann et al. profile →
  66. A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics
    2009 641 citations Jürgen Cox, Nagarjuna Nagaraj et al. profile →
  67. Online Parallel Accumulation–Serial Fragmentation (PASEF) with a Novel Trapped Ion Mobility Mass Spectrometer
    2018 635 citations Jürgen Cox, Matthias Mann et al. profile →
  68. Mass Spectrometry-based Proteomics Using Q Exactive, a High-performance Benchtop Quadrupole Orbitrap Mass Spectrometer
    2011 617 citations Annette Michalski, Nagarjuna Nagaraj et al. profile →
  69. Quantitative Interaction Proteomics and Genome-wide Profiling of Epigenetic Histone Marks and Their Readers
    2010 611 citations Jesper V. Olsen, Matthias Mann et al. profile →
  70. Comparative Proteomic Analysis of Eleven Common Cell Lines Reveals Ubiquitous but Varying Expression of Most Proteins
    2012 609 citations Tamar Geiger, Jüergen Cox et al. profile →
  71. Revisiting biomarker discovery by plasma proteomics
    2017 603 citations Matthias Mann et al. profile →
  72. Improved Resolution and Very High Sensitivity in MALDI TOF of Matrix Surfaces Made by Fast Evaporation
    1994 575 citations Matthias Mann et al. profile →
  73. Phosphotyrosine interactome of the ErbB‐receptor kinase family
    2005 574 citations Matthias Mann et al. profile →
  74. A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling
    2003 572 citations Matthias Mann et al. profile →
  75. Identification of the receptor component of the IκBα–ubiquitin ligase
    1998 557 citations Jens Andersen, Matthias Mann et al. profile →
  76. Cell type– and brain region–resolved mouse brain proteome
    2015 557 citations Kirti Sharma, Stefka Tyanova et al. profile →
  77. Phosphorylation and Inactivation of BAD by Mitochondria-Anchored Protein Kinase A
    1999 552 citations Matthias Mann et al. profile →
  78. The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins
    2006 541 citations Chanchal Kumar, Jesper V. Olsen et al. profile →
  79. Proteome-wide Analysis of Chaperonin-Dependent Protein Folding in Escherichia coli
    2005 519 citations Matthias Mann et al. profile →
  80. Quantitative, High-Resolution Proteomics for Data-Driven Systems Biology
    2011 519 citations Jürgen Cox, Matthias Mann profile →
  81. Status of Large-scale Analysis of Post-translational Modifications by Mass Spectrometry
    2013 441 citations Jesper V. Olsen, Matthias Mann profile →

Peers

Matthias Mann
Comparison fields: 5 of 214
  • Molecular Biology 150.8k
  • Spectroscopy 62.2k
  • Cell Biology 24.0k
  • Immunology 18.1k
  • Oncology 17.3k
Replace Steven P. Gygi with:
Steven P. Gygi United States
Ruedi Aebersold Switzerland
John R. Yates United States
Ulrich K. Laemmli Switzerland
A. Farr United States
Tony Hunter United States
Lewis C. Cantley United States
Peer Bork Germany
Roger Y. Tsien United States
Ad Bax United States
Steven P. Gygi United States View profile →
Citations per field, relative to Matthias Mann
Matthias Mann · 1×
Citations per year, relative to Matthias Mann
Matthias Mann · 1×

Countries citing papers authored by Matthias Mann

Since Specialization
Citations

This map shows the geographic impact of Matthias Mann's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Matthias Mann with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Matthias Mann more than expected).

Fields of papers citing papers by Matthias Mann

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Matthias Mann. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Matthias Mann. The network helps show where Matthias Mann may publish in the future.

Co-authorship network of co-authors of Matthias Mann

This figure shows the co-authorship network connecting the top 25 collaborators of Matthias Mann. A scholar is included among the top collaborators of Matthias Mann based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Matthias Mann. Matthias Mann is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
# Work Indexed citations
1
Noncanonical assembly, neddylation and chimeric cullin–RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex
2024 ·Nature Structural & Molecular Biology ·Daniel Horn‐Ghetko, (unknown), (unknown), Jiale Du, (unknown), (unknown), Viola Beier, Barbara Steigenberger, J. Rajan Prabu, (unknown), (unknown), Matthias Mann, Yue Xiong, Brenda A. Schulman
3
2
Proteomic Profiling of Colorectal Adenomas Identifies a Predictive Risk Signature for Development of Metachronous Advanced Colorectal Neoplasia
2023 ·Gastroenterology ·(unknown), Thilde Terkelsen, (unknown), Fabian Coscia, Sophia Doll, Siqi Zhao, Zhaojun Zhang, Nils Brünner, Jan Lindebjerg, (unknown), Xiangdong Fang, Matthias Mann, José M.A. Moreira
18
3
Activity-based profiling of cullin–RING E3 networks by conformation-specific probes
2023 ·Nature Chemical Biology ·Lukas T. Henneberg, (unknown), David M. Duda, Kheewoong Baek, David Yanishevski, Peter J. Murray, Matthias Mann, Sachdev S. Sidhu, Brenda A. Schulman
14
4
Urinary proteome profiling for stratifying patients with familial Parkinson’s disease
2021 ·EMBO Molecular Medicine ·Sebastian Virreira Winter, Özge Karayel, Maximilian T. Strauss, Shalini Padmanabhan, Matthew Surface, Kalpana Merchant, Roy N. Alcalay, Matthias Mann
84
5
AlphaMap: an open-source Python package for the visual annotation of proteomics data with sequence-specific knowledge
2021 ·Bioinformatics ·Eugenia Voytik, Isabell Bludau, Sander Willems, Fynn M. Hansen, Andreas‐David Brunner, Maximilian T. Strauss, Matthias Mann
12
6
DIA-based systems biology approach unveils E3 ubiquitin ligase-dependent responses to a metabolic shift
2020 ·Proceedings of the National Academy of Sciences ·Özge Karayel, André C. Michaelis, Matthias Mann, Brenda A. Schulman, Christine Langlois
19
7
In vivo brain GPCR signaling elucidated by phosphoproteomics
2018 ·Science ·Jeffrey J. Liu, Kirti Sharma, Luca Zangrandi, Chongguang Chen, Sean J. Humphrey, Yi-Ting Chiu, Mariana Spetea, Lee‐Yuan Liu‐Chen, Christoph Schwarzer, Matthias Mann
98
8
The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications
2018 ·Clinical Cancer Research ·Diego Iglesias‐Gato, Elin Thysell, Stefka Tyanova, Sead Crnalic, Alberto Santos, (unknown), Tamar Geiger, Jürgen Cox, Anders Widmark, Anders Bergh, Matthias Mann, Amilcar Flores‐Morales, Pernilla Wikström
66
9
PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex
2018 ·Nature Communications ·Stephanie Link, (unknown), (unknown), Mario Torrado, Moritz Völker-Albert, Eva C. Keilhauer, Thomas Burgold, (unknown), Jason K. K. Low, (unknown), Andrea Nist, Catherine Regnard, Thorsten Stiewe, Brian Hendrich, Axel Imhof, Matthias Mann, Joel P. Mackay, Marek Bartkuhn, Sandra B. Hake
42
10
Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis breakdown →
2017 ·eLife ·Martin Steger, Federico Diez, Herschel S. Dhekne, Paweł Lis, Raja Sekhar Nirujogi, Özge Karayel, Francesca Tonelli, Terina N. Martinez, Esben Lorentzen, Suzanne R. Pfeffer, Dario R. Alessi, Matthias Mann
329
11
Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links
2015 ·Science ·Markus Räschle, Godelieve Smeenk, (unknown), (unknown), Yasuyoshi Oka, Marco Y. Hein, Nagarjuna Nagaraj, David T. Long, Johannes C. Walter, Kay Hofmann, Zuzana Štorchová, Jürgen Cox, Simon Bekker‐Jensen, Niels Mailand, Matthias Mann
170
12
Direct Proteomic Quantification of the Secretome of Activated Immune Cells
2013 ·Science ·Felix Meissner, Richard A. Scheltema, Hans‐Joachim Mollenkopf, Matthias Mann
172
13
Proteomic Portrait of Human Breast Cancer Progression Identifies Novel Prognostic Markers
2012 ·Cancer Research ·Tamar Geiger, Stephen F. Madden, William M. Gallagher, Jüergen Cox, Matthias Mann
115
14
Decoding Human Cytomegalovirus breakdown →
2012 ·Science ·Noam Stern‐Ginossar, Ben Weisburd, Annette Michalski, Vu Thuy Khanh Le‐Trilling, Marco Y. Hein, Sheng‐Xiong Huang, (unknown), Ben Shen, Shu‐Bing Qian, Hartmut Hengel, Matthias Mann, Nicholas T. Ingolia, Jonathan S. Weissman
454
15
Caenorhabditis elegans Has a Phosphoproteome Atypical for Metazoans That Is Enriched in Developmental and Sex Determination Proteins
2009 ·Journal of Proteome Research ·Dorota Zielińska, Florian Gnad, (unknown), Jacek R. Wiśniewski, Matthias Mann
58
16
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions breakdown →
2009 ·Science ·Chunaram Choudhary, Chanchal Kumar, Florian Gnad, Michael L. Nielsen, Michael Rehman, Tobias C. Walther, Jesper V. Olsen, Matthias Mann
3252
17
Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing
2009 ·Science ·Celia J. Webby, Alexander Wolf, Natalia Gromak, Mathias Dreger, Holger Kramer, Benedikt M. Kessler, Michael L. Nielsen, Corinna Schmitz, Danica Butler, John R. Yates, Claire Delahunty, (unknown), Andreas Lengeling, Matthias Mann, Nicholas Proudfoot, Christopher J. Schofield, Angelika Böttger
315
18
In-depth analysis of the membrane and cytosolic proteome of red blood cells
2006 ·Blood ·Erica M. Pasini, (unknown), Peter Mortensen, Hans Lutz, Alan W. Thomas, Matthias Mann
331
19
Repo-Man recruits PP1γ to chromatin and is essential for cell viability
2006 ·The Journal of Cell Biology ·Laura Trinkle‐Mulcahy, Jens Andersen, Yun Wah Lam, Greg B. G. Moorhead, Matthias Mann, Angus I. Lamond
215
20
Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics
2003 ·Proceedings of the National Academy of Sciences ·Vamsi K. Mootha, Patricia Lepage, Kathleen A. Miller, Jakob Bunkenborg, Michael Reich, Majbrit Hjerrild, Terrye Delmonte, (unknown), Robert Sladek, Fenghao Xu, Grant A. Mitchell, Charles Morin, Matthias Mann, Thomas J. Hudson, Brian Robinson, John D. Rioux, Eric S. Lander
452

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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