Karen J. Coffman

2.7k total citations
18 papers, 414 citations indexed

About

Karen J. Coffman is a scholar working on Organic Chemistry, Molecular Biology and Physiology. According to data from OpenAlex, Karen J. Coffman has authored 18 papers receiving a total of 414 indexed citations (citations by other indexed papers that have themselves been cited), including 8 papers in Organic Chemistry, 6 papers in Molecular Biology and 5 papers in Physiology. Recurrent topics in Karen J. Coffman's work include Alzheimer's disease research and treatments (5 papers), Cholinesterase and Neurodegenerative Diseases (4 papers) and Chemical Reactions and Mechanisms (3 papers). Karen J. Coffman is often cited by papers focused on Alzheimer's disease research and treatments (5 papers), Cholinesterase and Neurodegenerative Diseases (4 papers) and Chemical Reactions and Mechanisms (3 papers). Karen J. Coffman collaborates with scholars based in United States, China and United Kingdom. Karen J. Coffman's co-authors include Patrick R. Verhoest, Richard F. Smith, Michael A. Brodney, Matthew M. Hayward, Yi Chen, Elie Needle, G. Stephen Noell, Ravi G. Kurumbail, Bethany L. Kormos and Zdenek Berger and has published in prestigious journals such as Journal of Medicinal Chemistry, Journal of Pharmacology and Experimental Therapeutics and Journal of Pharmaceutical Sciences.

In The Last Decade

Karen J. Coffman

18 papers receiving 404 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Karen J. Coffman United States 11 197 124 100 100 89 18 414
John R. Boot United Kingdom 13 214 1.1× 99 0.8× 79 0.8× 86 0.9× 56 0.6× 26 458
María Espelosin Spain 9 269 1.4× 59 0.5× 108 1.1× 55 0.6× 62 0.7× 13 369
E. G. Kireeva Russia 6 169 0.9× 61 0.5× 140 1.4× 38 0.4× 156 1.8× 15 360
Susana Ursúa Spain 8 258 1.3× 58 0.5× 105 1.1× 53 0.5× 56 0.6× 8 344
Ken-ichiro Kataoka Japan 8 166 0.8× 83 0.7× 97 1.0× 31 0.3× 239 2.7× 8 474
Hiroshi Shimadzu Japan 9 137 0.7× 77 0.6× 72 0.7× 46 0.5× 279 3.1× 17 443
S O Sablin United States 6 191 1.0× 31 0.3× 100 1.0× 68 0.7× 94 1.1× 9 343
Yamila Verdecia-Reyes Cuba 10 100 0.5× 56 0.5× 44 0.4× 53 0.5× 78 0.9× 27 315
Bertrand Le Bourdonnec United States 16 489 2.5× 511 4.1× 92 0.9× 105 1.1× 97 1.1× 38 1.0k
Isak Im South Korea 12 295 1.5× 147 1.2× 44 0.4× 16 0.2× 99 1.1× 16 534

Countries citing papers authored by Karen J. Coffman

Since Specialization
Citations

This map shows the geographic impact of Karen J. Coffman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karen J. Coffman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karen J. Coffman more than expected).

Fields of papers citing papers by Karen J. Coffman

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karen J. Coffman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karen J. Coffman. The network helps show where Karen J. Coffman may publish in the future.

Co-authorship network of co-authors of Karen J. Coffman

This figure shows the co-authorship network connecting the top 25 collaborators of Karen J. Coffman. A scholar is included among the top collaborators of Karen J. Coffman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Karen J. Coffman. Karen J. Coffman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

18 of 18 papers shown
1.
Filipski, Kevin J., David J. Edmonds, Michelle R. Garnsey, et al.. (2023). Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-Life. ACS Medicinal Chemistry Letters. 14(10). 1427–1433. 1 indexed citations
2.
Chen, Zhen, Jiahui Chen, Laigao Chen, et al.. (2022). Imaging Leucine-Rich Repeat Kinase 2 In Vivo with 18F-Labeled Positron Emission Tomography Ligand. Journal of Medicinal Chemistry. 66(3). 1712–1724. 10 indexed citations
3.
France, Scott P., Deane M. Nason, Roger M. Howard, et al.. (2020). Scalable, Telescoped Hydrogenolysis–Enzymatic Decarboxylation Process for the Asymmetric Synthesis of (R)-α-Heteroaryl Propionic Acids. Organic Process Research & Development. 25(3). 421–426. 8 indexed citations
4.
Widlicka, Daniel W., et al.. (2016). Two Routes to 4-Fluorobenzisoxazol-3-one in the Synthesis of a 5-HT4Partial Agonist. Organic Process Research & Development. 20(2). 233–241. 7 indexed citations
5.
Henderson, Jaclyn L., Bethany L. Kormos, Matthew M. Hayward, et al.. (2014). Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-yl)-7 H -pyrrolo[2,3- d ]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor. Journal of Medicinal Chemistry. 58(1). 419–432. 140 indexed citations
6.
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Brodney, Michael A., David E. Johnson, Aarti Sawant‐Basak, et al.. (2012). Identification of Multiple 5-HT4Partial Agonist Clinical Candidates for the Treatment of Alzheimer’s Disease. Journal of Medicinal Chemistry. 55(21). 9240–9254. 36 indexed citations
9.
Coffman, Karen J., Michael A. Brodney, James M. Cook, et al.. (2011). 6-Amino-4-(pyrimidin-4-yl)pyridones: Novel glycogen synthase kinase-3β inhibitors. Bioorganic & Medicinal Chemistry Letters. 21(5). 1429–1433. 25 indexed citations
10.
Lanz, Thomas A., Kathleen M. Wood, K. Richter, et al.. (2010). Pharmacodynamics and Pharmacokinetics of the γ-Secretase Inhibitor PF-3084014. Journal of Pharmacology and Experimental Therapeutics. 334(1). 269–277. 39 indexed citations
11.
Soares, Holly, Dane Liston, Karen J. Coffman, et al.. (2009). P1‐259: Aβ variability and effect of gamma secretase inhibition on cerebrospinal fluid levels of Aβ in healthy volunteers. Alzheimer s & Dementia. 5(4S_Part_8). 8 indexed citations
12.
Wood, Kathleen M., Thomas A. Lanz, Karen J. Coffman, et al.. (2008). P2‐375: Efficacy of the novel γ‐secretase inhibitor, PF‐3084014, in reducing Aβ in brain, CSF, and plasma in guinea pigs and Tg2576 mice. Alzheimer s & Dementia. 4(4S_Part_14). 11 indexed citations
13.
Rosen, Terry, Karen J. Coffman, Stafford McLean, et al.. (1998). Synthesis and structure-activity relationships of CP-122,721, a second-generation NK-1 receptor antagonist. Bioorganic & Medicinal Chemistry Letters. 8(3). 281–284. 28 indexed citations
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16.
Coffman, Karen J., et al.. (1983). ChemInform Abstract: AMIDRAZONES. 8. SYNTHESIS OF 1,2,4‐OXADIAZOLES BY THERMOLYSIS OF N3‐ACYLAMIDRAZONE YLIDES. Chemischer Informationsdienst. 14(36). 1 indexed citations
17.
Smith, Richard F., et al.. (1983). Amidrazones. 8. Synthesis of 1,2,4‐oxdiazoles by thermolysis of N3‐acylamidrazone ylides. Journal of Heterocyclic Chemistry. 20(1). 69–71. 5 indexed citations
18.
Smith, Richard F. & Karen J. Coffman. (1982). Deamination of Quaternary Hydrazinium Halides. A Convenient Synthesis of Tertiary Amines. Synthetic Communications. 12(10). 801–805. 16 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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