Tim F. Ryder

1.5k citations

20 papers · 659 indexed · h-index 11

Co-authors: Gregory S. Walker R. Scott Obach Chandra Prakash Sriram Krishnaswami Gary Chan Jinyan Lin Weiwei Wang Martin E. Dowty
Topics: Pharmacogenetics and Drug Metabolism (8 papers)Metabolomics and Mass Spectrometry Studies (5 papers)Drug Transport and Resistance Mechanisms (5 papers)
Cited by: Pharmacology Oncology Rheumatology
Journals: Journal of Medicinal Chemistry Journal of Pharmaceutical Sciences Chemical Research in Toxicology
Partner nations: United States Netherlands

In The Last Decade

Tim F. Ryder

20 papers receiving 634 citations

Peers

Countries citing papers authored by Tim F. Ryder

Since Specialization

Citations

This map shows the geographic impact of Tim F. Ryder's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tim F. Ryder with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tim F. Ryder more than expected).

Fields of papers citing papers by Tim F. Ryder

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tim F. Ryder. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tim F. Ryder. The network helps show where Tim F. Ryder may publish in the future.

Co-authorship network of co-authors of Tim F. Ryder

This figure shows the co-authorship network connecting the top 25 collaborators of Tim F. Ryder. A scholar is included among the top collaborators of Tim F. Ryder based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tim F. Ryder. Tim F. Ryder is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	An Automated Purification Workflow Coupled with Material-Sparing High-Throughput ¹H NMR for Parallel Medicinal Chemistry 2024 ·ACS Medicinal Chemistry Letters ·Justin Bellenger,Martin R. M. Koos,Melissa Avery,Mark W. Bundesmann,(unknown),Bhagyashree Khunte,Carolyn A. Leverett,(unknown),Tim F. Ryder,Kathleen A. Farley	3
2	Pharmacokinetics, mass balance, metabolism, and excretion of the liver-targeted acetyl-CoA carboxylase inhibitor PF-05221304 (clesacostat) in humans 2022 ·Xenobiotica ·Tim F. Ryder,Arthur Bergman,Amanda King‐Ahmad,Neeta B. Amin,Manjinder S. Lall,T. Eric Ballard,Amit S. Kalgutkar	3
3	Toward the assembly and characterization of an encoded library hit confirmation platform: Bead-Assisted Ligand Isolation Mass Spectrometry (BALI-MS) 2021 ·Bioorganic & Medicinal Chemistry ·Anokha S. Ratnayake,Mark E. Flanagan,Timothy L. Foley,(unknown),Justin Bellenger,Justin I. Montgomery,Manjinder S. Lall,Бо Лю,Tim F. Ryder,Dominik K. Kölmel,Andre Shavnya,Xidong Feng,Bruce A. Lefker,Laura J. Byrnes,Parag V. Sahasrabudhe,Kathleen A. Farley,Shi Chen,Jinqiao Wan	11
4	Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach 2019 ·Drug Metabolism and Disposition ·(unknown),Rohitash Jamwal,R. Scott Obach,Tim F. Ryder,Lorenzo Leggio,(unknown)	10
5	Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H -indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK) 2018 ·Journal of Medicinal Chemistry ·Tim F. Ryder,Matthew F. Calabrese,Gregory S. Walker,Kimberly O. Cameron,Allan R. Reyes,Kris A. Borzilleri,Jake Delmore,Russell Miller,Ravi G. Kurumbail,Jessica Ward,Daniel W. Kung,Janice A. Brown,David J. Edmonds,Heather Eng,Angela Wolford,Amit S. Kalgutkar	18
6	Distribution, Metabolism, and Excretion of Gedatolisib in Healthy Male Volunteers After a Single Intravenous Infusion 2018 ·Clinical Pharmacology in Drug Development ·Brett E. Houk,Christine Alvey,Ravi Visswanathan,(unknown),Kyle Matschke,Emi Kimoto,Tim F. Ryder,R. Scott Obach,Chandrasekar Durairaj	4
7	Biosynthesis of Drug Metabolites and Quantitation Using NMR Spectroscopy for Use in Pharmacologic and Drug Metabolism Studies 2014 ·Drug Metabolism and Disposition ·Gregory S. Walker,Jonathan Bauman,Tim F. Ryder,Evan B. Smith,Douglas K. Spracklin,R. Scott Obach	41
8	The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans 2014 ·Drug Metabolism and Disposition ·Martin E. Dowty,Jinyan Lin,Tim F. Ryder,Weiwei Wang,Gregory S. Walker,Alfin D. N. Vaz,Gary Chan,Sriram Krishnaswami,Chandra Prakash	212
9	Metabolism of a Serotonin-4 Receptor Partial Agonist 4-{4-[4-Tetrahydrofuran-3-yloxy)-Benzo[d]Isoxazol-3-yloxymethyl]-Piperidin-1-ylmethyl}-Tetrahydropyran-4-ol (TBPT): Identification of an Unusual Pharmacologically Active Cyclized Oxazolidine Metabolite in Human 2013 ·Journal of Pharmaceutical Sciences ·Aarti Sawant‐Basak,Karen J. Coffman,Gregory S. Walker,Tim F. Ryder,Elaine Tseng,Emily Miller,(unknown),Michelle Vanase‐Frawley,John W. Wong,Michael A. Brodney,(unknown),R. Scott Obach	12
10	Reactive Metabolite Trapping Studies on Imidazo- and 2-Methylimidazo[2,1-b]thiazole-Based Inverse Agonists of the Ghrelin Receptor 2013 ·Drug Metabolism and Disposition ·Amit S. Kalgutkar,Tim F. Ryder,Gregory S. Walker,Suvi T. M. Orr,Shawn Cabral,Theunis C. Goosen,Kimberly Lapham,Heather Eng	5
11	Metabolism, Excretion, and Pharmacokinetics of ((3,3-Difluoropyrrolidin-1-yl)((2S,4S)-4-(4-(pyrimidin-2-yl)piperazin-1-yl)pyrrolidin-2-yl)methanone, a Dipeptidyl Peptidase Inhibitor, in Rat, Dog and Human 2012 ·Drug Metabolism and Disposition ·Raman Sharma,Hao Sun,David W. Piotrowski,Tim F. Ryder,Shawn D. Doran,Haiqing Dai,Chandra Prakash	24
12	Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors 2012 ·Drug Metabolism and Disposition ·Robert L. Walsky,Jonathan Bauman,(unknown),(unknown),Kimberly Lapham,(unknown),Tim F. Ryder,R. Scott Obach,Ruth Hyland,Theunis C. Goosen	122
13	Insights into the Novel Hydrolytic Mechanism of a Diethyl 2-Phenyl-2-(2-arylacetoxy)methyl Malonate Ester-Based Microsomal Triglyceride Transfer Protein (MTP) Inhibitor 2012 ·Chemical Research in Toxicology ·Tim F. Ryder,Gregory S. Walker,Theunis C. Goosen,Roger B. Ruggeri,Edward L. Conn,Benjamin N. Rocke,Kimberly Lapham,Claire M. Steppan,David Hepworth,Amit S. Kalgutkar	5
14	Intrinsic Electrophilicity of a 4-Substituted-5-cyano-6-(2-methylpyridin-3-yloxy)pyrimidine Derivative: Structural Characterization of Glutathione Conjugates in Vitro 2011 ·Chemical Research in Toxicology ·Amit S. Kalgutkar,Vincent Mascitti,Raman Sharma,(unknown),Tim F. Ryder,Thomas S. McDonald,Yue Chen,Cathy Préville,Arindrajit Basak,Kim F. McClure,Jeffrey T. Kohrt,Ralph P. Robinson,Michael J. Munchhof,Peter Cornelius	15
15	Metabolism of Ramelteon in Human Liver Microsomes and Correlation with the Effect of Fluvoxamine on Ramelteon Pharmacokinetics 2010 ·Drug Metabolism and Disposition ·R. Scott Obach,Tim F. Ryder	30
16	Validation of Isolated Metabolites from Drug Metabolism Studies as Analytical Standards by Quantitative NMR 2010 ·Drug Metabolism and Disposition ·Gregory S. Walker,Tim F. Ryder,Raman Sharma,Evan B. Smith,Amy Freund	47
17	Species Differences in the Biotransformation of an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist: The Effects of Distinct Glucuronide Metabolites on Overall Compound Disposition 2009 ·Drug Metabolism and Disposition ·Christopher L. Shaffer,Mithat Gunduz,Tim F. Ryder,Thomas N. O’Connell	5
18	Quantitative Interference by Cysteine and N-Acetylcysteine Metabolites During the LC-MS/MS Bioanalysis of a Small Molecule 2009 ·Drug Metabolism Letters ·(unknown),Tim F. Ryder,Michael Furlong	7
19	Biotransformation of an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist in Sprague-Dawley Rats and the Dispositional Characterization of Its N-Carbamoyl Glucuronide Metabolite 2009 ·Drug Metabolism and Disposition ·Christopher L. Shaffer,Tim F. Ryder,Karthik Venkatakrishnan,(unknown),Thomas N. O’Connell	8
20	In VitroMetabolism and Covalent Binding of Enol-Carboxamide Derivatives and Anti-Inflammatory Agents Sudoxicam and Meloxicam: Insights into the Hepatotoxicity of Sudoxicam 2008 ·Chemical Research in Toxicology ·R. Scott Obach,Amit S. Kalgutkar,Tim F. Ryder,Gregory S. Walker	77

About Tim F. Ryder

Tim F. Ryder is a scholar working on Pharmacology, Endocrine and Autonomic Systems and Oncology, having authored 20 papers that have together received 659 indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (8 papers), Metabolomics and Mass Spectrometry Studies (5 papers) and Drug Transport and Resistance Mechanisms (5 papers). The work is most often cited by research in Pharmacology (264 citations), Oncology (148 citations) and Rheumatology (72 citations). Tim F. Ryder has collaborated with scholars based in United States and Netherlands. Frequent co-authors include Gregory S. Walker, R. Scott Obach, Chandra Prakash, Sriram Krishnaswami, Gary Chan, Jinyan Lin, Weiwei Wang, Martin E. Dowty, Alfin D. N. Vaz and Amit S. Kalgutkar. Their work appears in journals such as Journal of Medicinal Chemistry, Journal of Pharmaceutical Sciences and Chemical Research in Toxicology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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