Jayvardhan Pandit

4.6k citations

36 papers · 2.7k indexed · 1 hit paper · h-index 25

Impact in

Molecular Biology top 5%
- Glutathione Transferases and Polymorphisms
- Phosphodiesterase function and regulation
- Genomics, phytochemicals, and oxidative stress
- Receptor Mechanisms and Signaling
- Protein Structure and Dynamics
Pharmacology top 2%
- Cholinesterase and Neurodegenerative Diseases

Papers in

Molecular Biology 27
- Receptor Mechanisms and Signaling 8
- Phosphodiesterase function and regulation 7
- RNA and protein synthesis mechanisms 3
Organic Chemistry 11
- Synthesis and Characterization of Heterocyclic Compounds 3
- Carbohydrate Chemistry and Synthesis 3

Co-authors: Dennis E. Danley Gayle K. Schulte Frank S. Menniti Kieran F. Geoghegan Lise R. Hoth G F Ames ChulHee Kang S H Kim
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Journal of Medicinal Chemistry (6 papers)Journal of Biological Chemistry (4 papers)Acta Crystallographica Section C Crystal Structure Communications (3 papers)Proceedings of the National Academy of Sciences (2 papers)
Partner nations: United States United Kingdom Poland

In The Last Decade

Jayvardhan Pandit

34 papers receiving 2.7k citations

Hit Papers

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Identification, Characterization, and Crystal Structure of the Omega Class Glutathione Transferases 2000 · 606 citations

Peers

Countries citing papers authored by Jayvardhan Pandit

Since Specialization

Citations

This map shows the geographic impact of Jayvardhan Pandit's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jayvardhan Pandit with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jayvardhan Pandit more than expected).

Fields of papers citing papers by Jayvardhan Pandit

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jayvardhan Pandit. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jayvardhan Pandit. The network helps show where Jayvardhan Pandit may publish in the future.

Co-authors

The 25 scholars most cited alongside Jayvardhan Pandit, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jayvardhan Pandit Line = papers co-authored together Jayvardhan Pandit links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective Antagonists Molecular Pharmacology ·David Stroebel, Derek L. Buhl, John D. Knafels, Pranab K. Chanda, Michael Green, Simone Sciabola, Laétitia Mony, Pierre Paoletti, Jayvardhan Pandit	2016	85
2	Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads ACS Medicinal Chemistry Letters ·Carolyn A. Leverett, Sai Chetan K. Sukuru, Beth C. Vetelino, Sylvia Musto, Kevin Parris, Jayvardhan Pandit, Frank Loganzo, Alison H. Varghese, Guoyun Bai, Bin Liu, Dingguo Liu, Sarah P. Hudson, Venkata Ramana Doppalapudi, Joseph R. Stock, Christopher J. O’Donnell, Chakrapani Subramanyam	2016	27
3	Engineered stabilization and structural analysis of the autoinhibited conformation of PDE4 Proceedings of the National Academy of Sciences ·NG Xun, Ann Aulabaugh, Kieran F. Geoghegan, Thomas J. McLellan, Jayvardhan Pandit	2015	61
4	Allosteric Modulators for the Treatment of Schizophrenia: Targeting Glutamatergic Networks Current Topics in Medicinal Chemistry ·Frank S. Menniti, Craig W. Lindsley, P. Jeffrey Conn, Jayvardhan Pandit, Panayiotis Zagouras, Robert A. Volkmann	2013	64
5	PF-04859989 as a template for structure-based drug design: Identification of new pyrazole series of irreversible KAT II inhibitors with improved lipophilic efficiency Bioorganic & Medicinal Chemistry Letters ·Amy B. Dounay, Marie Anderson, Bruce M. Bechle, Edelweiss Evrard, X. Chen, Banafsheh Tavangar, Laura A. McAllister, Jayvardhan Pandit, Suo‐Bao Rong, Miguel Angel Maestro-Saavedra, Jamison B. Tuttle, Laura E. Zawadzke, Patrick R. Verhoest	2013	28
6	Discovery and Characterization of a Novel Dihydroisoxazole Class of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) Receptor Potentiators Journal of Medicinal Chemistry ·Nandini C. Patel, Jacob B. Schwarz, Xinjun Hou, Dennis J. Hoover, Longfei Xie, Ylva Bakketun, Randall J. Gallaschun, John T. Lazzaro, Dianne K. Bryce, William E. Hoffmann, Kewalin Somboon, Elizabeth Duxbury, Eric S. Marr, P. Solomon Lennox, Mihály Hajós, Renato J. Scialis, Raymond S Hurst, Christopher L. Shaffer, Jayvardhan Pandit, Christopher J. O’Donnell	2013	18
7	Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1 H -pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia†Coordinates of the PDE10A crystal structures have been deposited in the Protein Data Bank for compound 1 (3HQW), 2 (3HQY), 3 (3HQW) and 9 (3HR1). Journal of Medicinal Chemistry ·Patrick R. Verhoest, Douglas S. Chapin, Michael L. Corman, Kari R. Fonseca, John F. Harms, Xinjun Hou, Eric S. Marr, Frank S. Menniti, Frederick Nelson, Rebecca E. O’Connor, Jayvardhan Pandit, Agisni Fatihaturrohmah, Anne W. Schmidt, Christopher J. Schmidt, Arman Zan, Spiros Liras	2009	172
8	Potent and cellularly active 4-aminoimidazole inhibitors of cyclin-dependent kinase 5/p25 for the treatment of Alzheimer’s disease Bioorganic & Medicinal Chemistry Letters ·Christopher J. Helal, Zhijun Kang, W. Sichert-Oevermann, Thomas G. Gant, Michael K. Ahlijanian, Joel B. Schachter, K. Richter, James M. Cook, Frank S. Menniti, Kristin Kelly, Scot Mente, Jayvardhan Pandit, Natalie Hosea	2009	40
9	Cyclic Nucleotide Binding GAF Domains from Phosphodiesterases: Structural and Mechanistic Insights Structure ·Clemens C. Heikaus, Jayvardhan Pandit, Rachel E. Klevit	2009	76
10	Synthesis and structure based optimization of novel Akt inhibitors Bioorganic & Medicinal Chemistry Letters ·Blaise Lippa, Gonghua Pan, Matthew S. Corbett, Chao Li, Goss S. Kauffman, Jayvardhan Pandit, Shaughnessy Robinson, Liuqing Wei, DG Fry, Eric S. Marr, Gary Borzillo, Elisabeth Knauth, María Fernanda Briceño, Patrick W. Vincent, Salwa Bouabdallah, Deborah A. Baker, Francis Rajamohan, Shefali Kakar, Tracey Clark, Joel Morris	2008	64
11	The 2.0 Å crystal structure of the ERα ligand‐binding domain complexed with lasofoxifene Protein Science ·F.F. Vajdos, Lise R. Hoth, Kieran F. Geoghegan, Samuel P. Simons, Peter K. LeMotte, Dennis E. Danley, Mark Ammirati, Jayvardhan Pandit	2007	46
12	3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site Bioorganic & Medicinal Chemistry Letters ·Stephen W. Wright, Anthony Carlo, Dennis E. Danley, David Hageman, George A. Karam, Mahmoud N. Mansour, Lester D. McClure, Jayvardhan Pandit, Gayle K. Schulte, Judith L. Treadway, Ing-Kae Wang, Paul H. Bauer	2003	45
13	Activation of Human Liver Glycogen Phosphorylase by Alteration of the Secondary Structure and Packing of the Catalytic Core Molecular Cell ·Virginia L. Rath, Mark Ammirati, Peter K. LeMotte, Kimberly F. Fennell, Mahmoud N. Mansour, Dennis E. Danley, Thomas R. Hynes, Gayle K. Schulte, David J. Wasilko, Jayvardhan Pandit	2000	80
14	Crystal Structure of Human Squalene Synthase Journal of Biological Chemistry ·Jayvardhan Pandit, Dennis E. Danley, Gayle K. Schulte, Stacy Mazzalupo, Thomas Pauly, Cheryl M. Hayward, E.S. Hamanaka, John F. Thompson, H. James Harwood	2000	204
15	Identification, Characterization, and Crystal Structure of the Omega Class Glutathione Transferases Journal of Biological Chemistry ·Philip G. Board, Marjorie Coggan, Gareth Chelvanayagam, Simon Easteal, Lars S. Jermiin, Gayle K. Schulte, Dennis E. Danley, Lise R. Hoth, Matthew C. Griffor, Ajith V. Kamath, Michele H. Rosner, Boris A. Chrunyk, V. Vissarionov, Christopher A. Gabel, Kieran F. Geoghegan, Jayvardhan Pandit Hit paper breakdown →	2000	606
16	Inhibition of MMP-1 and MMP-13 with phosphinic acids that exploit binding in the S2 pocket Bioorganic & Medicinal Chemistry Letters ·Lawrence A. Reiter, James P. Rizzi, Jayvardhan Pandit, Deborah Tanner, Debduti Dutta, Vinod D. Parikh, James F. Blake, Dennis E. Danley, Ellen R. Laird, Arturo Lopez‐Anaya, Lori Lopresti‐Morrow, Mahmoud N. Mansour, M.D. Musfequzzaman, Peter G. Mitchell, Kang Yeonjin, Thomas Pauly, bo Li, Gayle K. Schulte, Sue A. Yocum	1999	31
17	High-resolution Structures of the Ligand Binding Domain of the Wild-type Bacterial Aspartate Receptor Journal of Molecular Biology ·Joanne I. Yeh, Hans-Peter Biemann, Gilbert G. Privé, Jayvardhan Pandit, Daniel E. Koshland, Sung‐Hou Kim	1996	130
18	High-resolution crystals and preliminary X-ray diffraction studies of a catalytic RNA Acta Crystallographica Section D Biological Crystallography ·KA Le-Cao, J. Bonar, J. Jancarik, Jayvardhan Pandit, Simone Anderton, Andrew Bohm, Ali Boushra Mhanna	1994	10
19	Three-Dimensional Structure of Dimeric Human Recombinant Macrophage Colony-Stimulating Factor Science ·Jayvardhan Pandit, Andrew Bohm, Janel Ames, Wenyun Yuan, Kirston Koths, Makrinioti Heidi	1992	148
20	L-Arginyl-L-glutamic acid dihydrate, C11H21N5O5.2H2O Acta Crystallographica Section C Crystal Structure Communications ·Jayvardhan Pandit, T. P. Seshadri, M. A. Viswamitra	1983	2

About Jayvardhan Pandit

Jayvardhan Pandit is a scholar working on Molecular Biology, Organic Chemistry, Computational Theory and Mathematics, Pharmacology and Toxicology, having authored 36 papers that have together received 2.7k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (8 papers), Phosphodiesterase function and regulation (7 papers), Computational Drug Discovery Methods (5 papers), Cholinesterase and Neurodegenerative Diseases (4 papers), Synthesis and Characterization of Heterocyclic Compounds (3 papers), Crystal structures of chemical compounds (3 papers), RNA and protein synthesis mechanisms (3 papers) and Carbohydrate Chemistry and Synthesis (3 papers). The work is most often cited by research in Molecular Biology (2.1k citations), Pharmacology (404 citations), Biological Psychiatry (51 citations), Cellular and Molecular Neuroscience (267 citations) and Biochemistry (101 citations). Jayvardhan Pandit has collaborated with scholars based in United States, United Kingdom and Poland. Frequent co-authors include Dennis E. Danley, Gayle K. Schulte, Frank S. Menniti, Kieran F. Geoghegan, Lise R. Hoth, G F Ames, ChulHee Kang, S H Kim, Byung‐Ha Oh and Kishiko Nikaido. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Journal of Biological Chemistry, Acta Crystallographica Section C Crystal Structure Communications and Proceedings of the National Academy of Sciences.

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