Michael G. Rosenfeld

98.6k citations

389 papers · 79.1k indexed · 40 hit papers · h-index 155

Molecular Biology top 0.01%
Genetics top 0.01%
Endocrinology, Diabetes and Metabolism top 0.02%
Cellular and Molecular Neuroscience top 0.05%
Cancer Research top 0.02%

Co-authors: Christopher K. Glass Ronald M. Evans David W. Rose Larry W. Swanson Susan Amara Riki Kurokawa Valentina Perissi Kenneth A. Ohgi
Topics: RNA Research and Splicing (80 papers)Genomics and Chromatin Dynamics (69 papers)Growth Hormone and Insulin-like Growth Factors (60 papers)
Cited by: Genetics Molecular Biology Endocrinology, Diabetes and Metabolism
Journals: Nature Science Cell
Partner nations: United States China South Korea

In The Last Decade

Michael G. Rosenfeld

387 papers receiving 77.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing

1983 2.0k citations Michael G. Rosenfeld, Susan Amara et al. Nature profile →
A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 1.9k citations Sheng‐Cai Lin, David W. Rose et al. profile →
The coregulator exchange in transcriptional functions of nuclear receptors

2000 1.8k citations Christopher K. Glass, Michael G. Rosenfeld profile →
Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

1982 1.8k citations Susan Amara, Michael G. Rosenfeld et al. Nature profile →
Molecular determinants of resistance to antiandrogen therapy

2003 1.8k citations Derek S. Welsbie, Sung Hee Baek et al. profile →
Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 1.7k citations Christopher K. Glass, Michael G. Rosenfeld et al. Nature profile →
Primary structure and expression of a functional human glucocorticoid receptor cDNA

1985 1.5k citations Michael G. Rosenfeld, Ronald M. Evans et al. Nature profile →
RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 1.1k citations Christopher K. Glass, Michael G. Rosenfeld et al. profile →
A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression

1997 1.1k citations Robert N. Eisenman, David W. Rose et al. Nature profile →
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ

2005 1.0k citations Amir Gamliel, Valentina Perissi et al. Nature profile →
Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1

1990 1000 citations Michael G. Rosenfeld et al. Nature profile →
Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes

1982 925 citations Michael G. Rosenfeld, Ronald M. Evans et al. Nature profile →
A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

1988 870 citations Michael G. Rosenfeld et al. profile →
Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription

2008 805 citations Xiaoyuan Song, Michael G. Rosenfeld et al. Nature profile →
Coactivator and corepressor complexes in nuclear receptor function

1999 784 citations Christopher K. Glass, Michael G. Rosenfeld et al. profile →
Functional domains of the human glucocorticoid receptor

1986 759 citations Michael G. Rosenfeld, Ronald M. Evans et al. profile →
A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

2009 758 citations Michael G. Rosenfeld, Christopher K. Glass et al. profile →
Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation

2013 755 citations Wenbo Li, Qi Ma et al. Nature profile →
Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response

2006 734 citations Michael G. Rosenfeld, Christopher K. Glass et al. profile →
Expression of a large family of POU-domain regulatory genes in mammalian brain development

1989 732 citations Michael G. Rosenfeld et al. Nature profile →
A Topoisomerase IIß-Mediated dsDNA Break Required for Regulated Transcription

2006 692 citations Valentina Perissi, Ivan García-Bassets et al. Science profile →
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.

1988 659 citations Michael G. Rosenfeld et al. profile →
CBP Histone Acetyltransferase Activity Is a Critical Component of Memory Consolidation

2004 659 citations Michael G. Rosenfeld et al. profile →
Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

2011 655 citations Dong Wang, Ivan García-Bassets et al. Nature profile →
Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

1996 615 citations Anatoli S. Gleiberman, Michael G. Rosenfeld et al. Nature profile →
Nuclear receptor coactivators

1997 603 citations Christopher K. Glass, David W. Rose et al. profile →
Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes

1998 550 citations Christopher K. Glass, Michael G. Rosenfeld et al. Proceedings of the National Academy of Sciences profile →
Transcription Factor-Specific Requirements for Coactivators and Their Acetyltransferase Functions

1998 546 citations David W. Rose, Christopher K. Glass et al. Science profile →
Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor

1987 542 citations Michael G. Rosenfeld et al. Nature profile →
Molecular Determinants of Crosstalk between Nuclear Receptors and Toll-like Receptors

2005 533 citations Jean Lozach, Christopher Benner et al. profile →
Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors.

1990 527 citations Michael G. Rosenfeld et al. profile →
Expression in Brain of a Messenger RNA Encoding a Novel Neuropeptide Homologous to Calcitonin Gene-Related Peptide

1985 520 citations Susan Amara, Ronald M. Evans et al. Science profile →
lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs

2013 520 citations Wenbo Li, Daria Merkurjev et al. Nature profile →
ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs

2011 514 citations Kenneth A. Ohgi, Michael G. Rosenfeld et al. profile →
Retinoic acid and thyroid hormone induce gene expression through a common responsive element

1988 509 citations Christopher K. Glass, Michael G. Rosenfeld et al. Nature profile →
Co-activators and co-repressors in the integration of transcriptional responses

1998 508 citations Christopher K. Glass, Michael G. Rosenfeld et al. profile →
Eya protein phosphatase activity regulates Six1–Dach–Eya transcriptional effects in mammalian organogenesis

2003 506 citations Kenneth A. Ohgi, Christopher K. Glass et al. Nature profile →
Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

1998 503 citations David W. Rose, Christopher K. Glass et al. profile →
Enhancers as non-coding RNA transcription units: recent insights and future perspectives

2016 503 citations Wenbo Li, Michael G. Rosenfeld et al. profile →
Activation of Cell-Specific Expression of Rat Growth Hormone and Prolactin Genes by a Common Transcription Factor

1988 466 citations Michael G. Rosenfeld et al. Science profile →

Peers

Countries citing papers authored by Michael G. Rosenfeld

Since Specialization

Citations

This map shows the geographic impact of Michael G. Rosenfeld's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael G. Rosenfeld with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael G. Rosenfeld more than expected).

Fields of papers citing papers by Michael G. Rosenfeld

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael G. Rosenfeld. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael G. Rosenfeld. The network helps show where Michael G. Rosenfeld may publish in the future.

Co-authorship network of co-authors of Michael G. Rosenfeld

This figure shows the co-authorship network connecting the top 25 collaborators of Michael G. Rosenfeld. A scholar is included among the top collaborators of Michael G. Rosenfeld based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael G. Rosenfeld. Michael G. Rosenfeld is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Ligand-specific regulation of a binary enhancer code dictating cellular senescence 2025 ·Proceedings of the National Academy of Sciences ·Thomas Suter,Meyer J. Friedman,Cagdas Tazearslan,Daria Merkurjev,(unknown),Dario Meluzzi,Michael G. Rosenfeld,(unknown)	2
2	Nonproteolytic ubiquitination regulates chromatin occupancy by the NCoR/SMRT/HDAC3 corepressor complex in MCF-7 breast cancer cells 2025 ·Proceedings of the National Academy of Sciences ·Giulio Ferrero,Maria Dafne Cardamone,Francesca Luca,(unknown),(unknown),Wen Liu,Yuan Gao,(unknown),A.K.M. Ghulam Muhammad,(unknown),Emma Smith,Tingyu Fan,Santina Cutrupi,Ivan García-Bassets,Michele De Bortoli,Michael G. Rosenfeld,Valentina Perissi	1
3	Enhancer–promoter specificity in gene transcription: molecular mechanisms and disease associations 2024 ·Experimental & Molecular Medicine ·(unknown),Tobias Wagner,(unknown),Michael G. Rosenfeld,Soohwan Oh	12
4	A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation 2024 ·Proceedings of the National Academy of Sciences ·Yohei Abe,Eric Kofman,Zhengyu Ouyang,(unknown),Nathanael J. Spann,Jason S. Seidman,Ty D. Troutman,Joshua D. Stender,Havilah Taylor,Weiwei Fan,Verena M. Link,Zeyang Shen,Juro Sakai,Michael Downes,Ronald M. Evans,James T. Kadonaga,Michael G. Rosenfeld,Christopher K. Glass	10
5	The 3D genome and its impacts on human health and disease 2023 ·PubMed ·Siqi Wang,Zhengyu Luo,(unknown),(unknown),Zhongying Zhao,Michael G. Rosenfeld,Xiaoyuan Song	11
6	Identification and functional validation of an enhancer variant in the 9p21.3 locus associated with glaucoma risk and elevated expression of p16 ^INK4a 2023 ·Aging Cell ·(unknown),Cagdas Tazearslan,Michael G. Rosenfeld,András Fiser,Yousin Suh	1
7	Signal-induced enhancer activation requires Ku70 to read topoisomerase1–DNA covalent complexes 2023 ·Nature Structural & Molecular Biology ·Yuliang Tan,Lu Yao,Amir Gamliel,Sreejith J. Nair,Havilah Taylor,(unknown),Aneel K. Aggarwal,Michael G. Rosenfeld	9
8	Long-distance association of topological boundaries through nuclear condensates 2022 ·Proceedings of the National Academy of Sciences ·Amir Gamliel,Dario Meluzzi,Soohwan Oh,Nan Jiang,Eugin Destici,Michael G. Rosenfeld,Sreejith J. Nair	16
9	Hippo signalling maintains ER expression and ER+ breast cancer growth 2021 ·Nature ·Shenghong Ma,ZhengMing Wu,Feng Yang,(unknown),Randy L. Johnson,Michael G. Rosenfeld,Kun‐Liang Guan	51
10	Enhancer release and retargeting activates disease-susceptibility genes 2021 ·Nature ·Soohwan Oh,Jiaofang Shao,Joydeep Mitra,Feng Xiong,Matteo D’Antonio,Ruoyu Wang,Ivan García-Bassets,Qi Ma,Xiaoyu Zhu,Joo‐Hyung Lee,Sreejith J. Nair,Feng Yang,Kenneth A. Ohgi,Kelly A. Frazer,Zhengdong D. Zhang,Wenbo Li,Michael G. Rosenfeld	85
11	Global epigenomic analysis of KSHV-infected primary effusion lymphoma identifies functional MYC superenhancers and enhancer RNAs 2020 ·Proceedings of the National Academy of Sciences ·Angela Park,Soohwan Oh,Kyle L. Jung,Un Yung Choi,Hye-Ra Lee,Michael G. Rosenfeld,Jae U. Jung	24
12	REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation–differentiation balance in the developing brain 2017 ·Proceedings of the National Academy of Sciences ·(unknown),Tamilla Nechiporuk,Sophia Jeng,Shannon K. McWeeney,Jianxun Wang,Michael G. Rosenfeld,Gail Mandel	52
13	Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules 2008 ·Proceedings of the National Academy of Sciences ·Qidong Hu,Young‐Soo Kwon,Esperanza Núñez,Maria Dafne Cardamone,Kasey R. Hutt,Kenneth A. Ohgi,Ivan García-Bassets,David W. Rose,Christopher K. Glass,Michael G. Rosenfeld,Xiangdong Fu	231
14	Genetic approaches identify adult pituitary stem cells 2008 ·Proceedings of the National Academy of Sciences ·Anatoli S. Gleiberman,Tatyana V. Michurina,Juan Manuel Encinas,(unknown),Peter Krasnov,(unknown),Gord Fishell,Michael G. Rosenfeld,Grigori Enikolopov	139
15	Sensitive ChIP-DSL technology reveals an extensive estrogen receptor α-binding program on human gene promoters 2007 ·Proceedings of the National Academy of Sciences ·Young‐Soo Kwon,Ivan García-Bassets,Kasey R. Hutt,Christine S. Cheng,Mingjie Jin,Dongyan Liu,Christopher Benner,Dong Wang,Zhen Ye,Marina Bibikova,Jian‐Bing Fan,Lingxun Duan,Christopher K. Glass,Michael G. Rosenfeld,Xiangdong Fu	101
16	Ligand-specific allosteric regulation of coactivator functions of androgen receptor in prostate cancer cells 2006 ·Proceedings of the National Academy of Sciences ·Sung Hee Baek,Kenneth A. Ohgi,Charles A. Nelson,Derek S. Welsbie,Charlie Chen,Charles L. Sawyers,David W. Rose,Michael G. Rosenfeld	62
17	Mnt-Deficient Mammary Glands Exhibit Impaired Involution and Tumors with Characteristics of Myc Overexpression 2006 ·Cancer Research ·Kazuhito Toyo‐oka,(unknown),Shinji Hirotsune,Zirong Li,Sonia Jain,Sara Ota,(unknown),Ivan García-Bassets,Jean Lozach,Michael G. Rosenfeld,Christopher K. Glass,Robert N. Eisenman,Bing Ren,Peter J. Hurlin,Anthony Wynshaw‐Boris	28
18	Transcriptional Regulation of Cortical Neuron Migration by POU Domain Factors 2002 ·Science ·Robert J. McEvilly,(unknown),Marcus D. Schonemann,Farideh Hooshmand,Michael G. Rosenfeld	208
19	Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth 1992 ·Nature ·(unknown),Sheng‐Cai Lin,Chia-Ping Chang,Michael G. Rosenfeld	268
20	RNA Processing Regulation of Neuroendorcrine Gene Expression 1982 ·DNA ·Ronald M. Evans,Susan Amara,Michael G. Rosenfeld	5

About Michael G. Rosenfeld

Michael G. Rosenfeld is a scholar working on Molecular Biology, Genetics and Endocrinology, Diabetes and Metabolism, having authored 389 papers that have together received 79.1k indexed citations. Recurring topics across this work include RNA Research and Splicing (80 papers), Genomics and Chromatin Dynamics (69 papers) and Growth Hormone and Insulin-like Growth Factors (60 papers). The work is most often cited by research in Genetics (22.4k citations), Molecular Biology (54.8k citations) and Endocrinology, Diabetes and Metabolism (12.9k citations). Michael G. Rosenfeld has collaborated with scholars based in United States, China and South Korea. Frequent co-authors include Christopher K. Glass, Ronald M. Evans, David W. Rose, Larry W. Swanson, Susan Amara, Riki Kurokawa, Valentina Perissi, Kenneth A. Ohgi, Joseph Torchia and Donna M. Simmons. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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