Frédéric Checler

22.1k total citations · 3 hit papers
267 papers, 15.7k citations indexed

About

Frédéric Checler is a scholar working on Molecular Biology, Physiology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Frédéric Checler has authored 267 papers receiving a total of 15.7k indexed citations (citations by other indexed papers that have themselves been cited), including 153 papers in Molecular Biology, 135 papers in Physiology and 112 papers in Cellular and Molecular Neuroscience. Recurrent topics in Frédéric Checler's work include Alzheimer's disease research and treatments (134 papers), Neuropeptides and Animal Physiology (60 papers) and Peptidase Inhibition and Analysis (57 papers). Frédéric Checler is often cited by papers focused on Alzheimer's disease research and treatments (134 papers), Neuropeptides and Animal Physiology (60 papers) and Peptidase Inhibition and Analysis (57 papers). Frédéric Checler collaborates with scholars based in France, United States and Canada. Frédéric Checler's co-authors include Cristine Alvès da Costa, Jean‐Pierre Vincent, Bruno Vincent, Patrick Kitabgi, Raphaëlle Pardossi‐Piquard, Karine Ancolio, Mounia Chami, Claire Sunyach, Huaxi Xu and Erwan Paitel and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Frédéric Checler

265 papers receiving 15.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Intraneuronal Aβ42 Accumulation in Human Brain

2000 833 citations Bruno Vincent, Frédéric Checler et al. American Journal Of Pathology profile →
Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain

1999 553 citations Dieder Moechars, Ilse Dewachter et al. Journal of Biological Chemistry profile →
Mitophagy in Alzheimer’s disease: Molecular defects and therapeutic approaches

2022 154 citations Fanny Eysert, Frédéric Checler et al. profile →

Peers

Countries citing papers authored by Frédéric Checler

Since Specialization

Citations

This map shows the geographic impact of Frédéric Checler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frédéric Checler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frédéric Checler more than expected).

Fields of papers citing papers by Frédéric Checler

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frédéric Checler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frédéric Checler. The network helps show where Frédéric Checler may publish in the future.

Co-authorship network of co-authors of Frédéric Checler

This figure shows the co-authorship network connecting the top 25 collaborators of Frédéric Checler. A scholar is included among the top collaborators of Frédéric Checler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frédéric Checler. Frédéric Checler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	α-synuclein expression in glioblastoma restores tumor suppressor function and rescues temozolomide drug resistance 2025 ·Cell Death and Disease ·Eric Duplan, (unknown), Thomas Goiran, (unknown), Mathew C. Casimiro, Richard G. Pestell, Shinya Tanaka, (unknown), Jérôme Honnorat, Ahmed Idbaïh, Lucie Martin, Hélène Castel, Frédéric Checler, Cristine Alvès da Costa	0
2	TFinder: A Python Web Tool for Predicting Transcription Factor Binding Sites 2024 ·Journal of Molecular Biology ·(unknown), Frédéric Checler, Eric Duplan, Cristine Alvès da Costa	4
3	Ectodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17 2024 ·Journal of Biological Chemistry ·Guillaume Dolla, Sarah Nicolas, (unknown), Alexandre Bourgeois, Raphaëlle Pardossi‐Piquard, Franck Bihl, Christelle Zaghrini, Joana Justino, Christine Payré, Pascal Mansuelle, Christoph Garbers, Pierre Ronco, Frédéric Checler, Gérard Lambeau, Agnès Petit-Paitel	5
4	The amyloid precursor protein and its derived fragments concomitantly contribute to the alterations of mitochondrial transport machinery in Alzheimer’s disease 2024 ·Cell Death and Disease ·(unknown), Fanny Eysert, (unknown), Paula Fernanda Kinoshita, Raphaëlle Pardossi‐Piquard, Charlotte Bauer, Sabiha Eddarkaoui, Luc Buée, Frédéric Checler, Mounia Chami	12
5	Potentially Pathogenic SORL1 Mutations Observed in Autosomal-Dominant Cases of Alzheimer’s Disease Do Not Modulate APP Physiopathological Processing 2023 ·Cells ·Charlotte Bauer, Eric Duplan, (unknown), Frédéric Checler	0
6	Parkin as a Molecular Bridge Linking Alzheimer’s and Parkinson’s Diseases? 2022 ·Biomolecules ·Frédéric Checler, Cristine Alvès da Costa	11
7	The Endoplasmic Reticulum Stress/Unfolded Protein Response and Their Contributions to Parkinson’s Disease Physiopathology 2020 ·Cells ·Cristine Alvès da Costa, (unknown), Eric Duplan, Frédéric Checler	82
8	Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation 2018 ·Cell Death and Differentiation ·Thomas Goiran, Eric Duplan, (unknown), (unknown), Inger Lauritzen, Julie Dunys, Han You, Frédéric Checler, Cristine Alvès da Costa	98
9	Eph receptors: New players in Alzheimer's disease pathogenesis 2014 ·Neurobiology of Disease ·Moustapha Cissé, Frédéric Checler	34
10	The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production 2012 ·Cell Death and Differentiation ·Guillaume Robert, Alexandre Puissant, Maeva Dufies, Sandrine Marchetti, Arnaud Jacquel, Thomas Cluzeau, Pascal Colosetti, Nathalie Belhacène, Philipp J. Kahle, Cristine Alvès da Costa, Frédéric Luciano, Frédéric Checler, Patrick Auberger	20
11	BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer’s disease 2012 ·Molecular Neurodegeneration ·L. Chami, Frédéric Checler	130
12	Parkin: Much More than a Simple Ubiquitin Ligase 2011 ·Neurodegenerative Diseases ·Cristine Alvès da Costa, Frédéric Checler	9
13	Aminopeptidase A contributes to the N‐terminal truncation of amyloid β‐peptide 2009 ·Journal of Neurochemistry ·Jean Sévalle, (unknown), Philippe Robert, Marie‐Claude Fournié‐Zaluski, Bernárd P. Roques, Frédéric Checler	88
14	TMP21 is a presenilin complex component that modulates γ-secretase but not ɛ-secretase activity 2006 ·Nature ·Fusheng Chen, Hiroshi Hasegawa, Gerold Schmitt‐Ulms, Toshitaka Kawarai, Christopher Böhm, Taiichi Katayama, Yongjun Gu, Nobuo Sanjo, (unknown), Ekaterina Rogaeva, Yosuke Wakutani, Raphaëlle Pardossi‐Piquard, (unknown), Anurag Tandon, Frédéric Checler, Philippe Marambaud, Kirk C. Hansen, David Westaway, Peter St George‐Hyslop, Paul Fraser	240
15	Primary Cultured Neurons Devoid of Cellular Prion Display Lower Responsiveness to Staurosporine through the Control of p53 at Both Transcriptional and Post-transcriptional Levels 2003 ·Journal of Biological Chemistry ·Erwan Paitel, Claire Sunyach, Cristine Alvès da Costa, Jean‐Christophe Bourdon, Bruno Vincent, Frédéric Checler	56
16	Prominent Cerebral Amyloid Angiopathy in Transgenic Mice Overexpressing the London Mutant of Human APP in Neurons 2000 ·American Journal Of Pathology ·Jo Van Dorpe, (unknown), Ilse Dewachter, Dieter Nuyens, Kurt Spittaels, Chris Van den Haute, Marc Mercken, Dieder Moechars, (unknown), Cuno Kuipéri, Koen Bruynseels, Ina Tesseur, Ruth J. F. Loos, Hugo Vanderstichele, Frédéric Checler, Raf Sciot, F. Van Leuven	189
17	Intracellular Aβ42 deposits and neurodegeneration in Alzeimer's disease 2000 ·Neuropathology ·Dehua Chui, (unknown), Takao Makifuchi, Haruhiko Akiyama, (unknown), Wataru Araki, Keikichi Takahashi, Frédéric Checler, Takeshi Tabira	1
18	Characterization of New Polyclonal Antibodies Specific for 40 and 42 Amino Acid-Long Amyloid β Peptides: Their Use to Examine the Cell Biology of Presenilins and the Immunohistochemistry of Sporadic Alzheimer’s Disease and Cerebral Amyloid Angiopathy Cases 1997 ·Molecular Medicine ·Hélène Barelli, (unknown), Jean Vizzavona, P. Delaère, Nathalie Chevallier, (unknown), Philippe Marambaud, Karine Ancolio, Joseph D. Buxbaum, Olga Khorkova, (unknown), Sudhir Sahasrabudhe, Jean Martínez, Jean‐Marie Warter, Michel Mohr, Frédéric Checler	126
19	Contribution of endopeptidase 3.4.24.15 to central neurotensin inactivation 1997 ·European Journal of Pharmacology ·Bruno Vincent, Jiřı́ Jiráček, Florence Noble, Mart Loog, Bernárd P. Roques, Vincent Dive, Jean‐Pierre Vincent, Frédéric Checler	32
20	[36] Neurolysin: Purification and assays 1995 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Frédéric Checler, Hélène Barelli, Pascale Dauch, Vincent Dive, Bruno Vincent, Jean‐Pierre Vincent	29

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact