Frédéric Checler

22.1k total citations · 3 hit papers
267 papers, 15.7k citations indexed

About

Frédéric Checler is a scholar working on Molecular Biology, Physiology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Frédéric Checler has authored 267 papers receiving a total of 15.7k indexed citations (citations by other indexed papers that have themselves been cited), including 153 papers in Molecular Biology, 135 papers in Physiology and 112 papers in Cellular and Molecular Neuroscience. Recurrent topics in Frédéric Checler's work include Alzheimer's disease research and treatments (134 papers), Neuropeptides and Animal Physiology (60 papers) and Peptidase Inhibition and Analysis (57 papers). Frédéric Checler is often cited by papers focused on Alzheimer's disease research and treatments (134 papers), Neuropeptides and Animal Physiology (60 papers) and Peptidase Inhibition and Analysis (57 papers). Frédéric Checler collaborates with scholars based in France, United States and Canada. Frédéric Checler's co-authors include Cristine Alvès da Costa, Jean‐Pierre Vincent, Bruno Vincent, Patrick Kitabgi, Raphaëlle Pardossi‐Piquard, Karine Ancolio, Mounia Chami, Claire Sunyach, Huaxi Xu and Erwan Paitel and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Frédéric Checler

265 papers receiving 15.4k citations

Hit Papers

Intraneuronal Aβ42 Accumu... 1999 2026 2008 2017 2000 1999 2022 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Intraneuronal Aβ42 Accumulation in Human Brain
    2000 833 citations Bruno Vincent, Frédéric Checler et al. American Journal Of Pathology profile →
  2. Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain
    1999 553 citations Dieder Moechars, Ilse Dewachter et al. Journal of Biological Chemistry profile →
  3. Mitophagy in Alzheimer’s disease: Molecular defects and therapeutic approaches
    2022 154 citations Frédéric Checler, Mounia Chami et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Frédéric Checler 8.6k 8.0k 4.8k 2.5k 2.2k 267 15.7k
Hui Zheng 8.4k 1.0× 7.2k 0.9× 3.3k 0.7× 2.1k 0.8× 784 0.4× 165 17.1k
Jorge Ghiso 11.8k 1.4× 8.5k 1.1× 1.9k 0.4× 1.8k 0.7× 2.0k 0.9× 213 17.3k
Robert Vassar 10.9k 1.3× 6.5k 0.8× 4.6k 0.9× 3.9k 1.6× 1.1k 0.5× 135 18.9k
Kelly R. Bales 12.1k 1.4× 6.1k 0.8× 3.9k 0.8× 2.8k 1.1× 1.5k 0.7× 126 17.1k
Eileen McGowan 7.0k 0.8× 4.9k 0.6× 3.0k 0.6× 1.9k 0.8× 1.0k 0.5× 113 12.7k
Edward H. Koo 17.2k 2.0× 11.6k 1.5× 5.1k 1.0× 4.8k 1.9× 1.7k 0.8× 187 23.7k
Christopher B. Eckman 9.3k 1.1× 5.9k 0.7× 2.3k 0.5× 2.4k 1.0× 810 0.4× 78 12.6k
Nobuhisa Iwata 6.8k 0.8× 4.4k 0.5× 2.9k 0.6× 1.8k 0.7× 781 0.4× 142 11.6k
Steven M. Paul 11.6k 1.3× 5.6k 0.7× 3.7k 0.8× 2.6k 1.1× 1.4k 0.6× 117 16.4k
Philip C. Wong 7.2k 0.8× 7.2k 0.9× 3.1k 0.6× 2.7k 1.1× 793 0.4× 148 16.6k

Countries citing papers authored by Frédéric Checler

Since Specialization
Citations

This map shows the geographic impact of Frédéric Checler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frédéric Checler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frédéric Checler more than expected).

Fields of papers citing papers by Frédéric Checler

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frédéric Checler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frédéric Checler. The network helps show where Frédéric Checler may publish in the future.

Co-authorship network of co-authors of Frédéric Checler

This figure shows the co-authorship network connecting the top 25 collaborators of Frédéric Checler. A scholar is included among the top collaborators of Frédéric Checler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frédéric Checler. Frédéric Checler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Duplan, Eric, Thomas Goiran, Mathew C. Casimiro, et al.. (2025). α-synuclein expression in glioblastoma restores tumor suppressor function and rescues temozolomide drug resistance. Cell Death and Disease. 16(1). 188–188.
2.
Lauritzen, Inger, A. Bini, Anne‐Sophie Gay, et al.. (2025). Presenilins as hub proteins controlling the endocytic and autophagic pathways and small extracellular vesicle secretion. Journal of Extracellular Vesicles. 14(1). e70019–e70019. 6 indexed citations
3.
Checler, Frédéric, et al.. (2024). TFinder: A Python Web Tool for Predicting Transcription Factor Binding Sites. Journal of Molecular Biology. 437(3). 168921–168921. 4 indexed citations
4.
Dolla, Guillaume, Sarah Nicolas, Alexandre Bourgeois, et al.. (2024). Ectodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17. Journal of Biological Chemistry. 300(7). 107480–107480. 5 indexed citations
5.
6.
Checler, Frédéric & Cristine Alvès da Costa. (2022). Parkin as a Molecular Bridge Linking Alzheimer’s and Parkinson’s Diseases?. Biomolecules. 12(4). 559–559. 11 indexed citations
7.
Dunys, Julie, Thomas Lorivel, Delphine Debayle, et al.. (2021). Dipeptidyl peptidase 4 contributes to Alzheimer’s disease–like defects in a mouse model and is increased in sporadic Alzheimer’s disease brains. Journal of Biological Chemistry. 297(2). 100963–100963. 17 indexed citations
8.
Costa, Cristine Alvès da, et al.. (2020). The Endoplasmic Reticulum Stress/Unfolded Protein Response and Their Contributions to Parkinson’s Disease Physiopathology. Cells. 9(11). 2495–2495. 82 indexed citations
9.
Prete, Dolores Del, Jan M. Suski, Bénédicte Oulès, et al.. (2016). Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes. Journal of Alzheimer s Disease. 55(4). 1549–1570. 128 indexed citations
10.
Shukla, Mayuri, Phitchayapak Wintachai, Jean‐François Hernandez, et al.. (2014). Melatonin stimulates the nonamyloidogenic processing of βAPP through the positive transcriptional regulation of ADAM10 and ADAM17. Journal of Pineal Research. 58(2). 151–165. 73 indexed citations
11.
Robert, Guillaume, Alexandre Puissant, Maeva Dufies, et al.. (2012). The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production. Cell Death and Differentiation. 19(11). 1769–1778. 20 indexed citations
12.
Chami, L. & Frédéric Checler. (2012). BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer’s disease. Molecular Neurodegeneration. 7(1). 52–52. 130 indexed citations
13.
Dorpe, Jo Van, Ilse Dewachter, Dieter Nuyens, et al.. (2000). Prominent Cerebral Amyloid Angiopathy in Transgenic Mice Overexpressing the London Mutant of Human APP in Neurons. American Journal Of Pathology. 157(4). 1283–1298. 189 indexed citations
14.
Chui, Dehua, Takao Makifuchi, Haruhiko Akiyama, et al.. (2000). Intracellular Aβ42 deposits and neurodegeneration in Alzeimer's disease. Neuropathology. 20. 21. 1 indexed citations
15.
Checler, Frédéric, Cristine Alvès da Costa, Karine Ancolio, et al.. (2000). Role of the proteasome in Alzheimer’s disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1502(1). 133–138. 84 indexed citations
16.
17.
Marambaud, Philippe, et al.. (1997). Contribution of the Proteasome to the α-Secretase Pathway in Alzheimer’s Disease. Advances in experimental medicine and biology. 421. 267–272. 5 indexed citations
18.
Checler, Frédéric, Hélène Barelli, Pascale Dauch, et al.. (1995). [36] Neurolysin: Purification and assays. Methods in enzymology on CD-ROM/Methods in enzymology. 593–614. 29 indexed citations
19.
Vincent, Bruno, Jean‐Pierre Vincent, & Frédéric Checler. (1994). Neurotensin and neuromedin N undergo distinct catabolic processes in murine astrocytes and primary cultured neurons. European Journal of Biochemistry. 221(1). 297–306. 16 indexed citations
20.
Checler, Frédéric, Jean‐Pierre Vincent, & Patrick Kitabgi. (1983). Neurotensin analogs [D-TYR11] and [D-PHE11]neurotensin resist degradation by brain peptidases in vitro and in vivo.. Journal of Pharmacology and Experimental Therapeutics. 227(3). 743–748. 57 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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