Nobuhisa Iwata

16.5k total citations · 5 hit papers
142 papers, 11.6k citations indexed

About

Nobuhisa Iwata is a scholar working on Physiology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Nobuhisa Iwata has authored 142 papers receiving a total of 11.6k indexed citations (citations by other indexed papers that have themselves been cited), including 75 papers in Physiology, 49 papers in Molecular Biology and 39 papers in Cellular and Molecular Neuroscience. Recurrent topics in Nobuhisa Iwata's work include Alzheimer's disease research and treatments (65 papers), Neuroscience and Neuropharmacology Research (17 papers) and Neuropeptides and Animal Physiology (14 papers). Nobuhisa Iwata is often cited by papers focused on Alzheimer's disease research and treatments (65 papers), Neuroscience and Neuropharmacology Research (17 papers) and Neuropeptides and Animal Physiology (14 papers). Nobuhisa Iwata collaborates with scholars based in Japan, United States and Switzerland. Nobuhisa Iwata's co-authors include Takaomi C. Saido, Makoto Higuchi, Satoshi Tsubuki, Yoshie Takaki, Takashi Saito, Jiro Takano, Emi Hama, Keiro Shirotani, Yukio Matsuba and Shu-Ming Huang and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Nobuhisa Iwata

140 papers receiving 11.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model

2007 1.6k citations Yasumasa Yoshiyama, Makoto Higuchi et al. Neuron profile →
Single App knock-in mouse models of Alzheimer's disease

2014 803 citations Takashi Saito, Yukio Matsuba et al. Nature Neuroscience profile →
Metabolic Regulation of Brain Aβ by Neprilysin

2001 772 citations Nobuhisa Iwata, Satoshi Tsubuki et al. profile →
Identification of the major Aβ1–42-degrading catabolic pathway in brain parenchyma: Suppression leads to biochemical and pathological deposition

2000 714 citations Nobuhisa Iwata, Satoshi Tsubuki et al. Nature Medicine profile →
Aβ Secretion and Plaque Formation Depend on Autophagy

2013 386 citations Per Nilsson, Misaki Sekiguchi et al. profile →

Peers

Countries citing papers authored by Nobuhisa Iwata

Since Specialization

Citations

This map shows the geographic impact of Nobuhisa Iwata's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nobuhisa Iwata with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nobuhisa Iwata more than expected).

Fields of papers citing papers by Nobuhisa Iwata

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nobuhisa Iwata. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nobuhisa Iwata. The network helps show where Nobuhisa Iwata may publish in the future.

Co-authorship network of co-authors of Nobuhisa Iwata

This figure shows the co-authorship network connecting the top 25 collaborators of Nobuhisa Iwata. A scholar is included among the top collaborators of Nobuhisa Iwata based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nobuhisa Iwata. Nobuhisa Iwata is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Proline‐rich transmembrane protein 2 regulates the magnitude and frequency of dopamine release by repetitive neuronal stimuli in the striatum of L‐dopa‐treated mice 2024 ·Neuropsychopharmacology Reports ·(unknown), (unknown), (unknown), Kaori Watanabe, (unknown), Shigeru Kawakami, Akira Kinoshita, Koh-ichiro Yoshiura, Naohiro Kurotaki, Keiro Shirotani, Nobuhisa Iwata	1
2	Identification and Characterization of Synaptic Vesicle Membrane Protein VAT-1 Homolog as a New Catechin-Binding Protein 2024 ·Biological and Pharmaceutical Bulletin ·(unknown), (unknown), (unknown), (unknown), Kaori Watanabe, Kaname Ohyama, Naotaka Kuroda, Takashi Tanaka, Keiro Shirotani, Nobuhisa Iwata	1
3	Alterations of ATG4A and LC3B in neurons derived from Alzheimer's disease patients 2023 ·Genes to Cells ·Keiro Shirotani, Kaori Watanabe, (unknown), Yumiko Kutoku, Yutaka Ohsawa, Yoshihide Sunada, Takayuki Kondo, Haruhisa Inoue, Nobuhisa Iwata	0
4	Proline-rich transmembrane protein 2 knock-in mice present dopamine-dependent motor deficits 2023 ·The Journal of Biochemistry ·(unknown), (unknown), (unknown), Kaori Watanabe, Tatsuya Kishino, Akira Kinoshita, Koh-ichiro Yoshiura, Naohiro Kurotaki, Keiro Shirotani, Nobuhisa Iwata	1
5	The role of TREM2 N-glycans in trafficking to the cell surface and signal transduction of TREM2 2022 ·The Journal of Biochemistry ·Keiro Shirotani, (unknown), (unknown), Kaori Watanabe, Nobuhisa Iwata	13
6	Local Action of Neprilysin Exacerbates Pressure Overload Induced Cardiac Remodeling 2021 ·Hypertension ·Hitoshi Nakagawa, Takuya Kumazawa, Kenji Onoue, Yasuki Nakada, Tomoya Nakano, Satomi Ishihara, Naoto Minamino, Hiroshi Hosoda, Nobuhisa Iwata, Tomoya Ueda, Ayako Seno, Taku Nishida, Tsunenari Soeda, Satoshi Okayama, Makoto Watanabe, Rika Kawakami, Yoshihiko Saito	4
7	Single App knock-in mouse models of Alzheimer's disease breakdown → 2014 ·Nature Neuroscience ·Takashi Saito, Yukio Matsuba, Naomi Mihira, Jiro Takano, Per Nilsson, Shigeyoshi Itohara, Nobuhisa Iwata, Takaomi C. Saido	803
8	Cellular models for individualized medicine in Alzheimer^\|^rsquo;s disease using patient-derived induced pluripotent stem cells 2014 ·Folia Pharmacologica Japonica ·Masashi Asai, Keiro Shirotani, Takayuki Kondo, Haruhisa Inoue, Nobuhisa Iwata	2
9	A role for calpain-dependent cleavage of TDP-43 in amyotrophic lateral sclerosis pathology 2012 ·Nature Communications ·Takenari Yamashita, Takuto Hideyama, (unknown), Sayaka Teramoto, Jiro Takano, Nobuhisa Iwata, Takaomi C. Saido, Shin Kwak	136
10	Cleavage of the Vesicular GABA Transporter under Excitotoxic Conditions Is Followed by Accumulation of the Truncated Transporter in Nonsynaptic Sites 2011 ·Journal of Neuroscience ·João R. Gomes, (unknown), Carlos V. Melo, Ana R. Inácio, Jiro Takano, Nobuhisa Iwata, Takaomi C. Saido, Luís Pereira de Almeida, Tadeusz Wieloch, Carlos B. Duarte	40
11	Altered Function of Factor I Caused by Amyloid β: Implication for Pathogenesis of Age-Related Macular Degeneration from Drusen 2008 ·The Journal of Immunology ·Jiying Wang, Kyoko Ohno‐Matsui, Takeshi Yoshida, Ariko Kojima, Noriaki Shimada, Ken‐ichi Nakahama, (unknown), Nobuhisa Iwata, Takaomi C. Saido, Manabu Mochizuki, Ikuo Morita	64
12	Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model 2007 ·Neuron ·Yasumasa Yoshiyama, Makoto Higuchi, Bin Zhang, Shu-Ming Huang, Nobuhisa Iwata, Takaomi C. Saido, Jun Maeda, Tetsuya Suhara, John Q. Trojanowski, Virginia M.‐Y. Lee	40
13	Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model breakdown → 2007 ·Neuron ·Yasumasa Yoshiyama, Makoto Higuchi, Bin Zhang, Shu-Ming Huang, Nobuhisa Iwata, Takaomi C. Saido, Jun Maeda, Tetsuya Suhara, John Q. Trojanowski, Virginia M.‐Y. Lee	1600
14	Understanding molecular mechanisms of proteolysis in Alzheimer's disease: Progress toward therapeutic interventions 2005 ·Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics ·Makoto Higuchi, Nobuhisa Iwata, Takaomi C. Saido	57
15	Inhibition of neprilysin by thiorphan (i.c.v.) causes an accumulation of amyloid β and impairment of learning and memory 2005 ·Behavioural Brain Research ·Akihiro Mouri, Li-Bo Zou, Nobuhisa Iwata, Takaomi C. Saido, Dayong Wang, (unknown), Yukihiro Noda, Toshitaka Nabeshima	40
16	Effects of Neprilysin Chimeric Proteins Targeted to Subcellular Compartments on Amyloid β Peptide Clearance in Primary Neurons 2004 ·Journal of Biological Chemistry ·Emi Hama, Keiro Shirotani, Nobuhisa Iwata, Takaomi C. Saido	45
17	Identification of the major Aβ1–42-degrading catabolic pathway in brain parenchyma: Suppression leads to biochemical and pathological deposition breakdown → 2000 ·Nature Medicine ·Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki, Kaori Watanabe, Misaki Sekiguchi, (unknown), (unknown), Hahn-Jun Lee, Emi Hama, Yoko Sekine‐Aizawa, Takaomi C. Saido	714
18	A RELATIONSHIP BETWEEN ELECTROCHEMICAL REDUCTION POTENTIAL AND THE ENZYMATIC REDUCTION OF NITRATED NAPHTHALENES BY MICROSOMES OR CYTOSOL FROM RAT LIVER 1993 ·The Journal of Toxicological Sciences ·Nobuhisa Iwata, Shuichi Hara, Takahiko Endo, Kiyoshi Fukuhara, Kazuhiro Suzuki, Atsushi Takahashi, Naoki Miyata	1
19	Changes and Localization of Ovarian Carbonyl Reductase during Pseudopregnancy and Pregnancy in Rats 1990 ·Biology of Reproduction ·Nobuhisa Iwata, Norihisa Inazu, Tetsuo Satoh	8
20	Identification of interchanged chromosomes in isogenic reciprocal translocation lines originated from rice variety Taichung 65. 1980 ·Akira Yoshimura, Nobuhisa Iwata, Tomohiro Omura	5

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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