David Westaway

3.5k total citations · 1 hit paper
29 papers, 2.8k citations indexed

About

David Westaway is a scholar working on Physiology, Molecular Biology and Computational Theory and Mathematics. According to data from OpenAlex, David Westaway has authored 29 papers receiving a total of 2.8k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Physiology, 13 papers in Molecular Biology and 7 papers in Computational Theory and Mathematics. Recurrent topics in David Westaway's work include Alzheimer's disease research and treatments (24 papers), Computational Drug Discovery Methods (7 papers) and Trace Elements in Health (6 papers). David Westaway is often cited by papers focused on Alzheimer's disease research and treatments (24 papers), Computational Drug Discovery Methods (7 papers) and Trace Elements in Health (6 papers). David Westaway collaborates with scholars based in Canada, United States and Belgium. David Westaway's co-authors include Peter St George‐Hyslop, M. Azhar Chishti, Christopher Janus, Howard T.J. Mount, JoAnne McLaurin, Paul E. Fraser, Paul M. Mathews, Stephen D. Schmidt, Ralph A. Nixon and Patrick Horne and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

David Westaway

28 papers receiving 2.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

2000 1.2k citations Christopher Janus, Jacqueline Pearson et al. Nature profile →

Peers

Countries citing papers authored by David Westaway

Since Specialization

Citations

This map shows the geographic impact of David Westaway's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Westaway with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Westaway more than expected).

Fields of papers citing papers by David Westaway

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Westaway. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Westaway. The network helps show where David Westaway may publish in the future.

Co-authorship network of co-authors of David Westaway

This figure shows the co-authorship network connecting the top 25 collaborators of David Westaway. A scholar is included among the top collaborators of David Westaway based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Westaway. David Westaway is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	TMP21 is a presenilin complex component that modulates γ-secretase but not ɛ-secretase activity 2006 ·Nature ·Fusheng Chen, Hiroshi Hasegawa, Gerold Schmitt‐Ulms, Toshitaka Kawarai, Christopher Böhm, Taiichi Katayama, Yongjun Gu, Nobuo Sanjo, (unknown), Ekaterina Rogaeva, Yosuke Wakutani, Raphaëlle Pardossi‐Piquard, (unknown), Anurag Tandon, Frédéric Checler, Philippe Marambaud, Kirk C. Hansen, David Westaway, Peter St George‐Hyslop, Paul Fraser	240
2	Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo 2006 ·Neurobiology of Disease ·(unknown), Zareen Amtul, Susan Newbigging, David Westaway, Peter St George‐Hyslop, Richard Rozmahel	8
3	Loss of nicastrin elicits an apoptotic phenotype in mouse embryos 2006 ·Brain Research ·Van Dan Nguyen, Cynthia Hawkins, Catherine Bergeron, Agnes Supala, Jean Huang, David Westaway, Peter St George‐Hyslop, Richard Rozmahel	23
4	Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model 2006 ·Nature Medicine ·JoAnne McLaurin, (unknown), Mary E. Brown, Cheryl A. Hawkes, Mark H. L. Lambermon, Amie L. Phinney, Audrey A. Darabie, (unknown), (unknown), (unknown), Fusheng Chen, (unknown), Howard T.J. Mount, Paul E. Fraser, David Westaway, Peter St George‐Hyslop	295
5	T313M PINK1 Mutation in an Extended Highly Consanguineous Saudi Family With Early-Onset Parkinson Disease 2006 ·Archives of Neurology ·M. Azhar Chishti, Saeed Bohlega, Maqbool Ahmed, (unknown), Pamela M. Carroll, Christine Sato, Peter St George‐Hyslop, David Westaway, Ekaterina Rogaeva	15
6	The Presenilin Proteins Are Components of Multiple Membrane-bound Complexes That Have Different Biological Activities 2004 ·Journal of Biological Chemistry ·(unknown), Nobuo Sanjo, Fusheng Chen, Hiroshi Hasegawa, Agnès Petit-Paitel, (unknown), Wenping Li, (unknown), Toshitaka Kawarai, Gerold Schmitt‐Ulms, David Westaway, Peter St George‐Hyslop, (unknown)	63
7	Potential roles for presenilin-1 in oxygen sensing and in glial-specific gene expression 2004 ·Neuroreport ·Jian-Guo Cui, Paul E. Fraser, Peter St George‐Hyslop, David Westaway, Walter J. Lukiw	8
8	Presenilin 1 and Presenilin 2 Have Differential Effects on the Stability and Maturation of Nicastrin in Mammalian Brain 2003 ·Journal of Biological Chemistry ·Fusheng Chen, Anurag Tandon, Nobuo Sanjo, Yongjun Gu, Hiroshi Hasegawa, Shigeki Arawaka, Frank J.S. Lee, (unknown), Peter Mastrangelo, (unknown), Linda Wang, David Westaway, Howard T.J. Mount, Bruce A. Yankner, Paul E. Fraser, Peter St George‐Hyslop	32
9	Alleles at the Nicastrin locus modify presenilin 1- deficiency phenotype 2002 ·Proceedings of the National Academy of Sciences ·Richard Rozmahel, Howard T.J. Mount, Fusheng Chen, Van Dan Nguyen, Jean Huang, (unknown), (unknown), Gang Yu, (unknown), Yongjun Gu, You‐Qiang Song, Stephen D. Schmidt, Ralph A. Nixon, Paul M. Mathews, Catherine Bergeron, Paul Fraser, David Westaway, Peter St George‐Hyslop	15
10	Presenilin 1 Mutations Activate γ42-Secretase but Reciprocally Inhibit ε-Secretase Cleavage of Amyloid Precursor Protein (APP) and S3-Cleavage of Notch 2002 ·Journal of Biological Chemistry ·Fusheng Chen, Yongjun Gu, Hiroshi Hasegawa, (unknown), Shigeki Arawaka, Paul Fraser, David Westaway, Howard T.J. Mount, Peter St George‐Hyslop	96
11	Normal brain development in PS1 hypomorphic mice with markedly reduced γ-secretase cleavage of βAPP 2002 ·Neurobiology of Aging ·Richard Rozmahel, Jean Huang, F. Chen, Yuh‐Jin Liang, Van Dan Nguyen, Masayuki Ikeda, Georges Lévesque, Gang Yu, Masaki Nishimura, Paul M. Mathews, Stephen D. Schmidt, Marc Mercken, C. Bergeron, David Westaway, Peter St George‐Hyslop	39
12	Aβ-immunization reduces learning impairment and amyloid plaque burden in an animal model of Alzheimer's disease 2002 ·European Neuropsychopharmacology ·David Westaway, Christopher Janus, (unknown), M. Azhar Chishti, JoAnne McLaurin, Paul M. Mathews, Yu Jiang, Stephen D. Schmidt, Patrick Horne, John B. French, Ralph A. Nixon, Marc Mercken, (unknown), C. Bergeron, George A. Carlson, Peter St George‐Hyslop	1
13	New developments in animal models of Alzheimer’s disease 2001 ·Current Neurology and Neuroscience Reports ·Christopher Janus, Amie L. Phinney, M. Azhar Chishti, David Westaway	28
14	Transgenic mouse models of Alzheimer’s disease 2000 ·Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Christopher Janus, M. Azhar Chishti, David Westaway	84
15	Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes 2000 ·Neurobiology of Aging ·Christopher Janus, Stefano D’Amelio, (unknown), M. Azhar Chishti, Robert Strome, Peter Fraser, George A. Carlson, John Roder, Peter St George‐Hyslop, David Westaway	66
16	Examining the zinc binding site of the amyloid‐β peptide 2000 ·European Journal of Biochemistry ·Dun‐Sheng Yang, JoAnne McLaurin, (unknown), David Westaway, Paul E. Fraser	102
17	Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease breakdown → 2000 ·Nature ·Christopher Janus, Jacqueline Pearson, JoAnne McLaurin, Paul M. Mathews, Ying Jiang, Stephen D. Schmidt, M. Azhar Chishti, Patrick Horne, (unknown), Jacqueline A. French, Howard T.J. Mount, Ralph A. Nixon, Marc Mercken, Catherine Bergeron, Paul E. Fraser, Peter St George‐Hyslop, David Westaway	1183
18	Developmental Expression of Wild-Type and Mutant Presenilin-1 in Hippocampal Neurons from Transgenic Mice: Evidence for Novel Species-Specific Properties of Human Presenilin-1 1999 ·Molecular Medicine ·Lyne Lévesque, Willem Annaert, Katleen Craessaerts, Paul M. Mathews, Mary Seeger, Ralph A. Nixon, (unknown), Sam Gandy, David Westaway, Peter St George‐Hyslop, Bart De Strooper, Paul E. Fraser	27
19	Aberrant Presenilin-1 Expression Downregulates LDL Receptor-Related Protein (LRP): Is LRP Central to Alzheimer's Disease Pathogenesis? 1999 ·Molecular and Cellular Neuroscience ·Emily Van Uden, George A. Carlson, Peter St George‐Hyslop, David Westaway, Robert A. Orlando, Margaret Mallory, Edward Rockenstein, Eliezer Masliah	32
20	Biology and genetics of the presenilin proteins associated with alzheimer disease 1997 ·The FASEB Journal ·Peter St George‐Hyslop, Georges Lévesque, Gang Yu, Masaki Ikeda, Masaki Nishimura, (unknown), Hiromi Mori, Bart De Strooper, Christian Haass, Dennis J. Selkoe, David Westaway, Peter Fraser	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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