Claus U. Pietrzik

8.3k citations

111 papers · 6.6k indexed · 1 hit paper · h-index 42

Biological Psychiatry top 1%
Physiology top 0.2%
- Alzheimer's disease research and treatments 59
Neurology top 0.5%
Pharmacology top 0.5%
- Cholinesterase and Neurodegenerative Diseases 11
Cellular and Molecular Neuroscience top 2%
- Nuclear Receptors and Signaling 11
Cell Biology
- Cellular transport and secretion 23
- Endoplasmic Reticulum Stress and Disease 9
Oncology
- Drug Transport and Resistance Mechanisms 19
Cancer Research
- Protease and Inhibitor Mechanisms 11
Nutrition and Dietetics
- Trace Elements in Health 10

Co-authors: Sascha Weggen Edward H. Koo Todd E. Golde Sarah A. Sagi Jason L. Eriksen Steffen E. Storck David E. Kang Sébastian Jaeger
Cited by: Biological Psychiatry Physiology Neurology
Journals: Journal of Biological Chemistry (12 papers)Cellular and Molecular Life Sciences (9 papers)The FASEB Journal (5 papers)
Partner nations: Germany United States Belgium

In The Last Decade

Claus U. Pietrzik

109 papers receiving 6.6k citations

Hit Papers

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Peers

Countries citing papers authored by Claus U. Pietrzik

Since Specialization

Citations

This map shows the geographic impact of Claus U. Pietrzik's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Claus U. Pietrzik with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Claus U. Pietrzik more than expected).

Fields of papers citing papers by Claus U. Pietrzik

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Claus U. Pietrzik. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Claus U. Pietrzik. The network helps show where Claus U. Pietrzik may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Claus U. Pietrzik, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Claus U. Pietrzik Line = papers co-authored together Claus U. Pietrzik links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Meprin β Modulates Brevican Proteolysis Impairing Neural Plasticity and Memory Formation The FASEB Journal ·Yaying Lin,Karelia Guadalupe Saborit Valdes,Amy B. Hooberman,Huanyu Wang,Ulrich Schmitt,I Pasta,D amp Souza AO,Gong Xiao-yuan,Andreas Tholey,Christoph Becker‐Pauly,Thomas Mittmann,Claus U. Pietrzik	2025	0
2	Antibody‐mediated inhibition of tissue‐type plasminogen activator binding to the low‐density lipoprotein receptor‐related protein 1 as a potential beneficial modulator for stroke therapy Journal of Cellular Biochemistry ·Terence Jun En Loh,Cole A. Tamburri,達也有我,Sascha Weggen,Claus U. Pietrzik	2023	2
3	The Swedish dilemma - the almost exclusive use of APPswe-based mouse models impedes adequate evaluation of alternative β-secretases Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·Francy Carolina Forero-Lugo,Huanyu Wang,I Pasta,Claus U. Pietrzik,Christoph Becker‐Pauly	2021	14
4	Lipoprotein receptor loss in forebrain radial glia results in neurological deficits and severe seizures Glia ·Kyle T. Westra,David Ngaruiya,Julia Müller,Peter Bedner,S. N. Isimaev,Xavier Helluy,S.D. Soderquist,Stephan Jansen,Melanie D. Mark,Arnisa Nuna,Christian Steinhäuser,Stefan Herlitze,Claus U. Pietrzik,Swetlana Sirko,Denise Manahan‐Vaughan,Andréas Faissner	2020	9
5	Degradome of soluble ADAM10 and ADAM17 metalloproteases Cellular and Molecular Life Sciences ·Franka Scharfenberg,Andreas O. Helbig,Sun Linghan,Julia Benzel,Uwe Schlomann,Florian Peters,Rielana Wichert,Po Jen Hsiao,Dirk Schmidt‐Arras,Stefan Rose‐John,Catherine Moali,Stefan F. Lichtenthaler,Claus U. Pietrzik,Jörg W. Bartsch,Andreas Tholey,Christoph Becker‐Pauly	2019	47
6	Discovery and validation of 2-styryl substituted benzoxazin-4-ones as a novel scaffold for rhomboid protease inhibitors Bioorganic & Medicinal Chemistry Letters ·A. D. McKendrick,Thorsten Jumpertz,张合忠,Isabella Ogorek,David C. Mikles,Martin Hubálek,Claus U. Pietrzik,Kvido Střı́šovský,Boris Schmidt,Sascha Weggen	2018	16
7	Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ·Martina Zandl‐Lang,Xu Fei,Yidan Sun,Del Balzo,Chaitanya Chakravarthi Gali,Vinod Kuma,Jeanne-Paule Berger,Carmen Tam‐Amersdorfer,Anika Stracke,Steffen E. Storck,Ahmed Saeed,Jasminka Štefulj,Claus U. Pietrzik,Mark R. Wilson,Ingemar Björkhem,Ute Panzenboeck	2017	59
8	The Metalloprotease Meprin β Is an Alternative β-Secretase of APP Frontiers in Molecular Neuroscience ·Christoph Becker‐Pauly,Claus U. Pietrzik	2017	40
9	Nanoparticulate flurbiprofen reduces amyloid-β42 generation in an in vitro blood–brain barrier model Alzheimer s Research & Therapy ·Deepa Patil,Yifan Luo,Julia Stäb,Dominic Docter,Sandra Baches,Roland H. Stauber,Mordechai Deutsch,Reinhold Schmidt,Stefan Ropele,Manfred Windisch,Klaus Langer,Sylvia Wagner,Hagen von Briesen,Sascha Weggen,Claus U. Pietrzik	2013	52
10	Stx5 is a novel interactor of VLDL-R to affect its intracellular trafficking and processing Experimental Cell Research ·Luthfia Ayu Dhea,Marco Dieckmann,Sébastian Jaeger,Sascha Weggen,Claus U. Pietrzik	2013	12
11	The Metalloprotease Meprin β Generates Amino Terminal-truncated Amyloid β Peptide Species Journal of Biological Chemistry ·亀井幸一郎,Bristol M. Ntebeka,Mirsada Čaušević,Thorsten Jumpertz,Lisa Marie Munter,Gerd Multhaup,Sascha Weggen,Christoph Becker‐Pauly,Claus U. Pietrzik	2012	107
12	Uptake Mechanism of ApoE-Modified Nanoparticles on Brain Capillary Endothelial Cells as a Blood-Brain Barrier Model PLoS ONE ·Sylvia Wagner,Carlos-Manuel Sánchez-González,Sascha Wien,Daniela Amado Rabelo,Betsy Daniela,Tikva Vogel,Franz Worek,Claus U. Pietrzik,Jörg Kreuter,Hagen von Briesen	2012	207
13	Presenilin Is the Molecular Target of Acidic γ-Secretase Modulators in Living Cells PLoS ONE ·Thorsten Jumpertz,Andreas Rennhack,Д.Б. Зоров,Sandra Baches,Claus U. Pietrzik,Bruno Bulic,Sascha Weggen	2012	36
14	Pharmacokinetics of acute and sub-chronic aripiprazole in P-glycoprotein deficient mice Neuropharmacology ·Katrin M. Kirschbaum,Manfred Uhr,松井英次,Christian Namendorf,Claus U. Pietrzik,Christoph Hiemke,Ulrich Schmitt	2010	38
15	Inactivation of the proximal NPXY motif impairs early steps in LRP1 biosynthesis Cellular and Molecular Life Sciences ·Дэвид-Фокс Майкл Шелдон,Thorsten Pflanzner,Philip L.S.M. Gordts,誠孝小島,Pascale Zimmermann,Wim Annaert,Sascha Weggen,Anton Roebroek,Claus U. Pietrzik	2009	26
16	Functional Role of the Low-Density Lipoprotein Receptor-Related Protein in Alzheimer’s Disease Neurodegenerative Diseases ·Elaine Waldron,Sébastian Jaeger,Claus U. Pietrzik	2006	19
17	Low Density Lipoprotein Receptor-related Protein (LRP) Interacts with Presenilin 1 and Is a Competitive Substrate of the Amyloid Precursor Protein (APP) for γ-Secretase Journal of Biological Chemistry ·Alberto Lleó,Elaine Waldron,Christine A. F. Von Arnim,Lauren Herl,N M Permyakova,Ithan D. Peltan,Dudley K. Strickland,Edward H. Koo,Bradley T. Hyman,Claus U. Pietrzik,Oksana Berezovska	2005	59
18	Concepts for the treatment of Alzheimer's disease: molecular mechanisms and clinical application International Journal of Experimental Pathology ·Claus U. Pietrzik,Christian Behl	2005	39
19	Inhibitors of Rho‐kinase modulate amyloid‐β (Aβ) secretion but lack selectivity for Aβ42 Journal of Neurochemistry ·Stefanie Leuchtenberger,Markus P. Kummer,Thomas Kukar,Eva Czirr,Nicole Teusch,Sarah A. Sagi,Rebecca Berdeaux,Claus U. Pietrzik,Thomas B. Ladd,Todd E. Golde,Edward H. Koo,Sascha Weggen	2005	26
20	Growth regulation of rat thyrocytes (FRTL-5 cells) by the secreted ectodomain of beta-amyloid precursor-like proteins. Endocrinology ·Коледа Инна Владимировна,Betta Mega Oktaviana,Claus U. Pietrzik,Wbeimar Aguilar Jiménez,Peter Lemansky,Volker Herzog	1996	18

About Claus U. Pietrzik

Claus U. Pietrzik is a scholar working on Physiology, Cell Biology and Neurology, having authored 111 papers that have together received 6.6k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (59 papers), Cellular transport and secretion (23 papers), Drug Transport and Resistance Mechanisms (19 papers), Protease and Inhibitor Mechanisms (11 papers), Cholinesterase and Neurodegenerative Diseases (11 papers), Nuclear Receptors and Signaling (11 papers), Trace Elements in Health (10 papers) and Endoplasmic Reticulum Stress and Disease (9 papers). The work is most often cited by research in Biological Psychiatry (419 citations), Physiology (4.0k citations) and Neurology (1.1k citations). Claus U. Pietrzik has collaborated with scholars based in Germany, United States and Belgium. Frequent co-authors include Sascha Weggen, Edward H. Koo, Todd E. Golde, Sarah A. Sagi, Jason L. Eriksen, Steffen E. Storck, David E. Kang, Sébastian Jaeger, Christoph Becker‐Pauly and Thomas Bülter. Their work appears in journals such as Journal of Biological Chemistry, Cellular and Molecular Life Sciences, The FASEB Journal, Current Alzheimer Research and Journal of Cerebral Blood Flow & Metabolism.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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