William E. Van Nostrand

11.1k citations

152 papers · 8.8k indexed · 2 hit papers · h-index 49

Impact in

Neurology top 0.2%
- Neuroinflammation and Neurodegeneration Mechanisms
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurological Disease Mechanisms and Treatments
Physiology top 0.1%
- Alzheimer's disease research and treatments

Papers in

Physiology 130
- Alzheimer's disease research and treatments 129
Neurology 33
- Intracerebral and Subarachnoid Hemorrhage Research 36
- Neuroinflammation and Neurodegeneration Mechanisms 22
- Cerebrovascular and genetic disorders 15

Co-authors: Judianne Davis Feng Xu Dennis D. Cunningham Steven O. Smith Mary Lou Previti Darryl Aucoin Mahiuddin Ahmed Jerry P. Melchor
Journals: Journal of Biological Chemistry (22 papers)Biochemistry (11 papers)Proceedings of the National Academy of Sciences (8 papers)Journal of Neuroscience (8 papers)Annals of the New York Academy of Sciences (7 papers)
Partner nations: United States Netherlands United Kingdom

In The Last Decade

William E. Van Nostrand

152 papers receiving 8.7k citations

Hit Papers

align trajectories log scale

Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils 2010 · 949 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2010 Nature Structural & Molecular Biology
2004 Neuron

Peers

Countries citing papers authored by William E. Van Nostrand

Since Specialization

Citations

This map shows the geographic impact of William E. Van Nostrand's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William E. Van Nostrand with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William E. Van Nostrand more than expected).

Fields of papers citing papers by William E. Van Nostrand

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William E. Van Nostrand. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William E. Van Nostrand. The network helps show where William E. Van Nostrand may publish in the future.

Co-authorship network

The 25 scholars most cited alongside William E. Van Nostrand, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with William E. Van Nostrand Line = papers co-authored together William E. Van Nostrand links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Is CAA a perivascular brain clearance disease? A discussion of the evidence to date and outlook for future studies Cellular and Molecular Life Sciences ·Susanne J. van Veluw, Helene Benveniste, Erik N.T.P. Bakker, Roxana O. Carare, Steven M. Greenberg, Jeffrey J. Iliff, 蒋石磊, William E. Van Nostrand, Gabor C. Petzold, Andy Y. Shih, Matthias J.P. van Osch	2024	16
2	Cerebrospinal fluid shotgun proteomics identifies distinct proteomic patterns in cerebral amyloid angiopathy rodent models and human patients Acta Neuropathologica Communications ·za Olivia Díaz Oropeza, С Г Али-Заде, Anna M. de Kort, Iris Kersten, Hans J. C. T. Wessels, Catharina J.M. Klijn, Floris H.B.M. Schreuder, H. Bea Kuiperij, Jolein Gloerich, William E. Van Nostrand, Marcel M. Verbeek	2024	7
3	Elevated expression of urokinase plasminogen activator in rodent models and patients with cerebral amyloid angiopathy Neuropathology and Applied Neurobiology ·za Olivia Díaz Oropeza, Xiaoyue Zhu, С Г Али-Заде, Anna M. de Kort, Tainá M. Marques, Iris Kersten, Esref Gursel A, Wilson F. Abdo, Floris H.B.M. Schreuder, Saeid Jan Abadi, Gisela M. Terwindt, Marieke J.H. Wermer, Steven M. Greenberg, Catharina J.M. Klijn, H. Bea Kuiperij, William E. Van Nostrand, Marcel M. Verbeek	2022	2
4	Long-term voluntary wheel running does not alter vascular amyloid burden but reduces neuroinflammation in the Tg-SwDI mouse model of cerebral amyloid angiopathy Journal of Neuroinflammation ·Lisa S. Robison, MorisawaDaisuke, 王俊博, R.Alejandro Sica, Joshua Hatfield, Sofia Nofianti, Светислав Љ. Марковић, Feng Xu, Brenda J. Anderson, William E. Van Nostrand, John K. Robinson	2019	25
5	Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure Nature Communications ·Feng Xu, Ziao Fu, Jack Bernard Cobetto, Nelly Agassi, Judianne Davis, Steven O. Smith, William E. Van Nostrand	2016	31
6	The influence of the amyloid ß-protein and its precursor in modulating cerebral hemostasis Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·William E. Van Nostrand	2015	16
7	Data on thrombotic ischemic lesions in the presence or absence of amyloid ß-protein precursor or its homolog amyloid precursor-like protein-2 in mice Data in Brief ·Feng Xu, William E. Van Nostrand	2015	2
8	Restricted V gene usage and VH/VL pairing of mouse humoral response against the N-terminal immunodominant epitope of the amyloid β peptide Molecular Immunology ·R. Robert, Marie‐Paule Lefranc, Anahit Ghochikyan, Michael G. Agadjanyan, David H. Cribbs, William E. Van Nostrand, Kim L. Wark, Olan Dolezal	2010	15
9	Early-onset subicular microvascular amyloid and neuroinflammation correlate with behavioral deficits in vasculotropic mutant amyloid β-protein precursor transgenic mice Neuroscience ·Feng Xu, Lazos Panagiotis, J. Robinson, Mary Lou Previti, Michael J. Vasek, Jennifer Davis, William E. Van Nostrand	2007	80
10	Experimental Investigation of Antibody-Mediated Clearance Mechanisms of Amyloid-β in CNS of Tg-SwDI Transgenic Mice Journal of Neuroscience ·Vitaly Vasilevko, Feng Xu, Mary Lou Previti, William E. Van Nostrand, David H. Cribbs	2007	44
11	Induction of complement proteins in a mouse model for cerebral microvascular Aβ deposition Journal of Neuroinflammation ·Rong Fan, 高亚飞, William E. Van Nostrand	2007	40
12	Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD. Journal of Neuroinflammation ·Carol A. Colton, Ryan T. Mott, Hayley J. Sharpe, Qing Xu, William E. Van Nostrand, Michael P. Vitek	2006	340
13	Dexamethasone diminishes the pro-inflammatory and cytotoxic effects of amyloid β-protein in cerebrovascular smooth muscle cells Journal of Neuroinflammation ·Mary Lou Previti, Weibing Zhang, William E. Van Nostrand	2006	20
14	Deficient cerebral clearance of vasculotropic mutant Dutch/Iowa Double Aß in human AßPP transgenic mice Neurobiology of Aging ·Judianne Davis, Feng Xu, Jianting Miao, Mary Lou Previti, Galina Romanov, Imam Suwardi, William E. Van Nostrand	2005	48
15	Assembly of hereditary amyloid β‐protein variants in the presence of favorable gangliosides FEBS Letters ·Naoki Yamamoto, Yoshio Hirabayashi, Masakuni Amari, Haruyasu Yamaguchi, Galina Romanov, William E. Van Nostrand, Katsuhiko Yanagisawa	2005	57
16	Binding of amyloid β precursor protein to coagulation factor XIa in vivo may favour haemorrhagic stroke Journal of Neurology ·Marjolijn Bornebroek, Peter A. von dem Borne, Joost Haan, Joost C.M. Meijers, William E. Van Nostrand, Raymund A.C. Roos	1998	5
17	Enhanced Plasmin Inhibition by a Reactive Center Lysine Mutant of the Kunitz-type Protease Inhibitor Domain of the Amyloid β-Protein Precursor Journal of Biological Chemistry ·William E. Van Nostrand, Alvin H. Schmaier, Robert S. Siegel, Steven L. Wagner, William C. Raschke	1995	18
18	Zinc (II) selectively enhances the inhibition of coagulation factor XIa by protease nexin-2/amyloid β-Protein precursor Thrombosis Research ·William E. Van Nostrand	1995	28
19	Protease nexin-2/amyloid beta protein precursor. A tight-binding inhibitor of coagulation factor IXa. Journal of Clinical Investigation ·Alvin H. Schmaier, Lina Dahl, Annemieke J.M. Rozemüller, R. A. C. Roos, Steven L. Wagner, Raymond T. Chung, William E. Van Nostrand	1993	91
20	Purification of a form of protease nexin-1 that binds heparin with a low affinity Biochemistry ·William E. Van Nostrand, Steven L. Wagner, Dennis D. Cunningham	1988	20

About William E. Van Nostrand

William E. Van Nostrand is a scholar working on Physiology, Neurology, Neurology, Cancer Research and Clinical Biochemistry, having authored 152 papers that have together received 8.8k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (129 papers), Intracerebral and Subarachnoid Hemorrhage Research (36 papers), Protease and Inhibitor Mechanisms (25 papers), Amyloidosis: Diagnosis, Treatment, Outcomes (24 papers), Neuroinflammation and Neurodegeneration Mechanisms (22 papers), Prion Diseases and Protein Misfolding (21 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (15 papers) and Cerebrovascular and genetic disorders (15 papers). The work is most often cited by research in Neurology (2.1k citations), Physiology (6.4k citations), Biological Psychiatry (301 citations), Neurology (1.3k citations) and Cellular and Molecular Neuroscience (1.2k citations). William E. Van Nostrand has collaborated with scholars based in United States, Netherlands and United Kingdom. Frequent co-authors include Judianne Davis, Feng Xu, Dennis D. Cunningham, Steven O. Smith, Mary Lou Previti, Darryl Aucoin, Mahiuddin Ahmed, Jerry P. Melchor, Carol A. Colton and Jeffrey S. Farrow. Their work appears in journals such as Journal of Biological Chemistry, Biochemistry, Proceedings of the National Academy of Sciences, Journal of Neuroscience and Annals of the New York Academy of Sciences.

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