Stefan Rose‐John

67.1k total citations · 19 hit papers
564 papers, 47.9k citations indexed

About

Stefan Rose‐John is a scholar working on Oncology, Immunology and Molecular Biology. According to data from OpenAlex, Stefan Rose‐John has authored 564 papers receiving a total of 47.9k indexed citations (citations by other indexed papers that have themselves been cited), including 325 papers in Oncology, 281 papers in Immunology and 153 papers in Molecular Biology. Recurrent topics in Stefan Rose‐John's work include Cytokine Signaling Pathways and Interactions (239 papers), Immune Response and Inflammation (67 papers) and Immune Cell Function and Interaction (62 papers). Stefan Rose‐John is often cited by papers focused on Cytokine Signaling Pathways and Interactions (239 papers), Immune Response and Inflammation (67 papers) and Immune Cell Function and Interaction (62 papers). Stefan Rose‐John collaborates with scholars based in Germany, United States and United Kingdom. Stefan Rose‐John's co-authors include Jürgen Scheller, Athena Chalaris, Dirk Schmidt‐Arras, Christoph Garbers, Simon A. Jones, Peter C. Heinrich, Joachim Grötzinger, Jürgen Müllberg, Heidi Schooltink and Georg H. Waetzig and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Stefan Rose‐John

558 papers receiving 47.2k citations

Hit Papers

The pro- and anti-inflammatory propertie... 1994 2026 2004 2015 2011 2009 2012 2011 2001 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The pro- and anti-inflammatory properties of the cytokine interleukin-6
    2011 2.5k citations Jürgen Scheller, Athena Chalaris et al. profile →
  2. IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
    2009 1.7k citations Jürgen Scheller, Stefan Rose‐John et al. profile →
  3. IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6
    2012 794 citations Stefan Rose‐John profile →
  4. Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer
    2011 671 citations Stefan Rose‐John et al. profile →
  5. IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation
    2001 667 citations Stefan Rose‐John et al. profile →
  6. Soluble receptors for cytokines and growth factors: generation and biological function
    1994 651 citations Stefan Rose‐John et al. profile →
  7. IL-6 pathway in the liver: From physiopathology to therapy
    2016 645 citations Stefan Rose‐John et al. profile →
  8. TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling
    2004 590 citations Hans A. Lehr, Alexei Nikolaev et al. profile →
  9. The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion
    2003 588 citations Stefan Rose‐John et al. Blood profile →
  10. A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia
    2014 555 citations Stefan Rose‐John et al. profile →
  11. Interleukin-6 Family Cytokines
    2017 554 citations Stefan Rose‐John profile →
  12. Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer
    2006 529 citations Stefan Rose‐John, Jürgen Scheller et al. profile →
  13. Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
    2011 528 citations Simon A. Jones, Jürgen Scheller et al. profile →
  14. Soluble gp130 is the natural inhibitor of soluble interleukin‐6 receptor transsignaling responses
    2001 526 citations Suat Özbek, Raja Atreya et al. profile →
  15. Interleukin-6 and its receptors: A highly regulated and dynamic system
    2014 469 citations Stefan Rose‐John, Christoph Garbers et al. profile →
  16. Interleukin-6: designing specific therapeutics for a complex cytokine
    2018 466 citations Christoph Garbers, Stefan Rose‐John et al. profile →
  17. Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner
    2020 370 citations Stefan Rose‐John et al. profile →
  18. Targeting IL-6 trans-signalling: past, present and future prospects
    2023 271 citations Stefan Rose‐John, Brendan J. Jenkins et al. profile →
  19. Interleukin-6: obstacles to targeting a complex cytokine in critical illness
    2021 155 citations Stefan Rose‐John et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Stefan Rose‐John Germany 109 18.4k 17.4k 13.7k 6.0k 5.0k 564 47.9k
Kouji Matsushima Japan 116 25.6k 1.4× 12.9k 0.7× 11.8k 0.9× 4.2k 0.7× 4.3k 0.9× 562 49.2k
Robert M. Strieter United States 133 23.9k 1.3× 17.1k 1.0× 12.7k 0.9× 6.5k 1.1× 4.3k 0.9× 509 56.9k
John J. O’Shea United States 110 31.2k 1.7× 15.2k 0.9× 11.2k 0.8× 3.6k 0.6× 3.1k 0.6× 323 49.8k
Paola Allavena Italy 93 33.3k 1.8× 22.0k 1.3× 14.6k 1.1× 4.1k 0.7× 6.9k 1.4× 295 56.8k
Silvano Sozzani Italy 95 25.7k 1.4× 12.6k 0.7× 10.6k 0.8× 4.2k 0.7× 2.8k 0.6× 314 41.1k
Steven L. Kunkel United States 113 21.6k 1.2× 9.8k 0.6× 9.7k 0.7× 6.3k 1.1× 3.0k 0.6× 528 48.1k
Josef Penninger Austria 133 18.0k 1.0× 14.8k 0.8× 40.9k 3.0× 5.1k 0.9× 7.5k 1.5× 582 78.3k
Georg Schett Germany 118 18.0k 1.0× 8.7k 0.5× 21.6k 1.6× 3.7k 0.6× 4.3k 0.9× 1.1k 59.6k
Jo Van Damme Belgium 108 16.7k 0.9× 13.7k 0.8× 12.7k 0.9× 3.0k 0.5× 4.4k 0.9× 547 41.8k
Hideo Yagita∥ Japan 128 43.5k 2.4× 21.7k 1.2× 18.2k 1.3× 5.2k 0.9× 6.4k 1.3× 912 67.3k

Countries citing papers authored by Stefan Rose‐John

Since Specialization
Citations

This map shows the geographic impact of Stefan Rose‐John's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stefan Rose‐John with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stefan Rose‐John more than expected).

Fields of papers citing papers by Stefan Rose‐John

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stefan Rose‐John. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stefan Rose‐John. The network helps show where Stefan Rose‐John may publish in the future.

Co-authorship network of co-authors of Stefan Rose‐John

This figure shows the co-authorship network connecting the top 25 collaborators of Stefan Rose‐John. A scholar is included among the top collaborators of Stefan Rose‐John based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stefan Rose‐John. Stefan Rose‐John is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Klapproth, Erik, Christoph Becker‐Pauly, Sebastian Zeißig, et al.. (2025). Type I interferon limits interleukin-6 signalling in SLE through shedding interleukin-6 receptors. Lara D. Veeken. 64(11). 5793–5802.
2.
Rose‐John, Stefan & Simon A. Jones. (2024). More and more pleiotropy within the IL‐6 family of cytokines. FEBS Journal. 292(3). 519–522. 2 indexed citations
3.
Wood, Richard K., et al.. (2024). Idiopathic multicentric Castleman disease with marrow fibrosis and extramedullary hematopoiesis. European Journal Of Haematology. 113(6). 833–841. 2 indexed citations
4.
Choi, Na Young, et al.. (2022). Enhancement of proliferation of human umbilical cord blood–derived CD34+ hematopoietic stem cells by a combination of hyper-interleukin-6 and small molecules. Biochemistry and Biophysics Reports. 29. 101214–101214. 3 indexed citations
5.
Kasper, Philipp, Christina Vohlen, Ruth Janoschek, et al.. (2021). Brain-Restricted Inhibition of IL-6 Trans-Signaling Mildly Affects Metabolic Consequences of Maternal Obesity in Male Offspring. Nutrients. 13(11). 3735–3735. 3 indexed citations
6.
Shriki, Anat, Amir Sonnenblick, Rinat Abramovitch, et al.. (2021). Multiple Roles of IL6 in Hepatic Injury, Steatosis, and Senescence Aggregate to Suppress Tumorigenesis. Cancer Research. 81(18). 4766–4777. 16 indexed citations
7.
Wilkinson, A, Rachel D. Kuns, Andrea Henden, et al.. (2019). IL-6 dysregulation originates in dendritic cells and mediates graft-versus-host disease via classical signaling. Blood. 134(23). 2092–2106. 32 indexed citations
8.
Prystaz, Katja, Anna Kovtun, Melanie Haffner‐Luntzer, et al.. (2017). Distinct Effects of IL-6 Classic and Trans -Signaling in Bone Fracture Healing. American Journal Of Pathology. 188(2). 474–490. 99 indexed citations
9.
Marmary, Yitzhak, Alexander Maly, Jonathan Cohen, et al.. (2016). Radiation-Induced Loss of Salivary Gland Function Is Driven by Cellular Senescence and Prevented by IL6 Modulation. Cancer Research. 76(5). 1170–1180. 97 indexed citations
10.
McLeod, Louise, Sultan Alhayyani, Alistair Miller, et al.. (2016). IL6 Trans-signaling Promotes KRAS-Driven Lung Carcinogenesis. Cancer Research. 76(4). 866–876. 95 indexed citations
11.
Ruwanpura, Saleela M., Louise McLeod, Lovisa Dousha, et al.. (2016). Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema. American Journal of Respiratory and Critical Care Medicine. 194(12). 1494–1505. 39 indexed citations
12.
Braun, Gerald S., Yuichi Maruta, Felix Heymann, et al.. (2015). IL-6 Trans-Signaling Drives Murine Crescentic GN. Journal of the American Society of Nephrology. 27(1). 132–142. 49 indexed citations
13.
Schlecker, Eva, Nathalie Fiegler, Annette Arnold, et al.. (2014). Metalloprotease-Mediated Tumor Cell Shedding of B7-H6, the Ligand of the Natural Killer Cell–Activating Receptor NKp30. Cancer Research. 74(13). 3429–3440. 169 indexed citations
14.
Quarta, Serena, Nadja Scherbakov, Manfred Andratsch, et al.. (2014). Peripheral Nerve Regeneration and NGF-Dependent Neurite Outgrowth of Adult Sensory Neurons Converge on STAT3 Phosphorylation Downstream of Neuropoietic Cytokine Receptor gp130. Journal of Neuroscience. 34(39). 13222–13233. 52 indexed citations
15.
Gerlach, Katharina, Carolin Daniel, Hans A. Lehr, et al.. (2012). Transcription Factor NFATc2 Controls the Emergence of Colon Cancer Associated with IL-6–Dependent Colitis. Cancer Research. 72(17). 4340–4350. 52 indexed citations
16.
Dewitz, Christin, Katja Möller‐Hackbarth, Jürgen Scheller, et al.. (2012). Effects of Blockade of Peripheral Interleukin-6 Trans-Signaling on Hippocampus-Dependent and Independent Memory in Mice. Journal of Interferon & Cytokine Research. 33(5). 254–260. 7 indexed citations
17.
Bender, Markus, Sebastian Hofmann, David Stegner, et al.. (2010). Differentially regulated GPVI ectodomain shedding by multiple platelet–expressed proteinases. Blood. 116(17). 3347–3355. 98 indexed citations
18.
Lo, Chi‐Wen, Min‐Wei Chen, Michael Hsiao, et al.. (2010). IL-6 Trans-Signaling in Formation and Progression of Malignant Ascites in Ovarian Cancer. Cancer Research. 71(2). 424–434. 152 indexed citations
19.
Rabe, Björn, et al.. (2009). Interleukin-6 Trans-Signaling Regulates Glycogen Consumption After d -Galactosamine-Induced Liver Damage. Journal of Interferon & Cytokine Research. 29(11). 711–718. 13 indexed citations
20.
Dingley, Andrew J., et al.. (2003). Direct Determination of the Interleukin-6 Binding Epitope of the Interleukin-6 Receptor by NMR Spectroscopy. Journal of Biological Chemistry. 279(1). 571–576. 12 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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