Sean Chia

2.3k citations

46 papers · 1.5k indexed · h-index 21

Impact in

Physiology top 2%
- Alzheimer's disease research and treatments
Aging top 10%

Papers in

Physiology 26
- Alzheimer's disease research and treatments 25
Computational Theory and Mathematics 9
- Computational Drug Discovery Methods 9

Co-authors: Michele Vendruscolo Johnny Habchi Tuomas P. J. Knowles Christopher M. Dobson Sara Linse Francesco Simone Ruggeri Thomas C. T. Michaels Samuel I. A. Cohen
Journals: ACS Chemical Neuroscience (6 papers)Communications Biology (3 papers)Proceedings of the National Academy of Sciences (3 papers)Science Advances (3 papers)Biophysical Journal (3 papers)
Partner nations: United Kingdom Sweden Singapore

In The Last Decade

Sean Chia

44 papers receiving 1.5k citations

Peers

Countries citing papers authored by Sean Chia

Since Specialization

Citations

This map shows the geographic impact of Sean Chia's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sean Chia with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sean Chia more than expected).

Fields of papers citing papers by Sean Chia

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sean Chia. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sean Chia. The network helps show where Sean Chia may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Sean Chia, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Sean Chia Line = papers co-authored together Sean Chia links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Maturation-dependent changes in the size, structure and seeding capacity of Aβ42 amyloid fibrils Communications Biology ·Alyssa Miller, Sean Chia, Ewa Klimont, Tuomas P. J. Knowles, Michele Vendruscolo, Francesco Simone Ruggeri	2024	6
2	HSPB6: A lipid-dependent molecular chaperone inhibits α-synuclein aggregation iScience ·Margot Morrell, Marta Cobb, 行雄田丸, Fábio R. Assis Neto, Sean Chia, Michele Vendruscolo, Serena Carra	2024	5
3	Antibody glycan quality predicted from CHO cell culture media markers and machine learning Computational and Structural Biotechnology Journal ·Meiyappan Lakshmanan, Sean Chia, Kuin Tian Pang, Saverio La Dogana, Gavin Teo, Shi Ya Mak, Shuwen Chen, Hsueh Lee Lim, Alison Lee, Floux (17..-18..? ; patron-pêcheur). Auteur du texte, Say Kong Ng, Yuansheng Yang, Rongping Lin, Andy Hee‐Meng Tan, Andre Choo, Ying Swan Ho, Terry Nguyen‐Khuong, Ian Walsh	2024	2
4	Nanoparticle-based Biosensors for Detection of Heavy Metal Ions Amanda J. Carter, Mohammad Nuzaihan Md Nor, Valentín Carrascosa López, Sean Chia, Chi‐Ho Ng, 周喜丹, M. F. M. Fathil, Aurél Marton	2024	0
5	Insight into muscle stem cell regeneration and mechanobiology Stem Cell Research & Therapy ·Kuin Tian Pang, Larry Sai Weng Loo, Sean Chia, F. Ong, Hanry Yu, Ian Walsh	2023	22
6	Enhancing pharmacokinetic and pharmacodynamic properties of recombinant therapeutic proteins by manipulation of sialic acid content Biomedicine & Pharmacotherapy ·Sean Chia, Boehme Joachim, Zhiwei Song, Yuansheng Yang, Ian Walsh, Kuin Tian Pang	2023	21
7	Secondary Processes Dominate the Quiescent, Spontaneous Aggregation of α-Synuclein at Physiological pH with Sodium Salts ACS Chemical Neuroscience ·Raymond D. Jorgensen, Michael A. Metrick, ARMIN HETZER, Kaibo Nan, Z. Faidon Brotzakis, Sean Chia, Georg Meisl, Michele Vendruscolo	2023	13
8	Optimization of a small molecule inhibitor of secondary nucleation in α-synuclein aggregation Frontiers in Molecular Biosciences ·行雄田丸, Z. Faidon Brotzakis, Sean Chia, Raymond D. Jorgensen, Michele Vendruscolo	2023	7
9	A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers Communications Biology ·Rodrigo Cataldi, Sean Chia, Lizhi YANG, Francesco Simone Ruggeri, Catherine K. Xu, Tomas Šneideris, Michele Perni, Erin Spelman, Priyanka Joshi, Janet R. Kumita, Sara Linse, Johnny Habchi, Tuomas P. J. Knowles, Benedetta Mannini, Christopher M. Dobson, Michele Vendruscolo	2021	36
10	Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response Communications Biology ·Priyanka Joshi, Michele Perni, Ryan Limbocker, Benedetta Mannini, Seung Jong Lee, Sean Chia, Johnny Habchi, Johnathan Labbadia, Christopher M. Dobson, Michele Vendruscolo	2021	14
11	Infrared nanospectroscopy reveals the molecular interaction fingerprint of an aggregation inhibitor with single Aβ42 oligomers Nature Communications ·Francesco Simone Ruggeri, Johnny Habchi, Sean Chia, Raymond D. Jorgensen, Michele Vendruscolo, Tuomas P. J. Knowles	2021	55
12	Surface-Catalyzed Secondary Nucleation Dominates the Generation of Toxic IAPP Aggregates Frontiers in Molecular Biosciences ·Diana C. Rodriguez Camargo, Sean Chia, Chenmian Zhou, Benedetta Mannini, Georg Meisl, Martin Lundqvist, Miguel Ángel Garro Cerna, Katja Bernfur, F. G. Youssef, Johnny Habchi, Samuel I. A. Cohen, Tuomas P. J. Knowles, Michele Vendruscolo, Sara Linse	2021	29
13	Screening of small molecules using the inhibition of oligomer formation in α-synuclein aggregation as a selection parameter Communications Chemistry ·行雄田丸, Thomas C. T. Michaels, Patrick Flagmeier, Sean Chia, Raymond D. Jorgensen, Johnny Habchi, Sara Linse, Tuomas P. J. Knowles, Christopher M. Dobson, Michele Vendruscolo	2020	36
14	Expression, purification and characterisation of large quantities of recombinant human IAPP for mechanistic studies Biophysical Chemistry ·Martin Lundqvist, Diana C. Rodriguez Camargo, Katja Bernfur, Sean Chia, Sara Linse	2020	12
15	Bacterial production and direct functional screening of expanded molecular libraries for discovering inhibitors of protein aggregation Science Advances ·Thomas Wissingh, Sean Chia, Johnny Habchi, Michele Perni, M Kolesnikov Alexander, Nikoletta Papaevgeniou, Martin Reczko, Niki Chondrogianni, Christopher M. Dobson, Michele Vendruscolo, Γεώργιος Σκρέτας	2019	15
16	Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy Journal of Visualized Experiments ·Francesco Simone Ruggeri, Tomas Šneideris, Sean Chia, Michele Vendruscolo, Tuomas P. J. Knowles	2019	2
17	Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy Journal of Visualized Experiments ·Francesco Simone Ruggeri, Tomas Šneideris, Sean Chia, Michele Vendruscolo, Tuomas P. J. Knowles	2019	14
18	Modulating Amyloid-Beta Aggregation to Reduce the Toxicity of its Oligomeric Aggregates Biophysical Journal ·Ryan Limbocker, Benedetta Mannini, Sean Chia, Francesco Simone Ruggeri, Michele Perni, Roberta Cascella, Catherine K. Xu, Johnny Habchi, Janet R. Kumita, Fabrizio Chiti, Tuomas P. J. Knowles, Michele Vendruscolo, Christopher M. Dobson	2018	1
19	Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity Nature Communications ·Francesco Simone Ruggeri, Jérôme Charmet, Віталій Кислий, Quentin Peter, Sean Chia, Johnny Habchi, Christopher M. Dobson, Michele Vendruscolo, Tuomas P. J. Knowles	2018	40
20	Systematic Development of Small Molecules to Inhibit Specific Microscopic Steps of Amyloid-Beta42 Aggregation in Alzheimer's Disease Biophysical Journal ·Sean Chia, Johnny Habchi, Ryan Limbocker, Benedetta Mannini, Minkoo Ahn, Michele Perni, Oskar Hansson, Paolo Arosio, Janet R. Kumita, Pavan K. Challa, Samuel I. A. Cohen, Sara Linse, Christopher M. Dobson, Tuomas P. J. Knowles, Michele Vendruscolo	2018	1

About Sean Chia

Sean Chia is a scholar working on Physiology, Computational Theory and Mathematics, Complementary and Manual Therapy, Biological Psychiatry and Neurology, having authored 46 papers that have together received 1.5k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (25 papers), Computational Drug Discovery Methods (9 papers), Protein Structure and Dynamics (7 papers), Parkinson's Disease Mechanisms and Treatments (6 papers), Monoclonal and Polyclonal Antibodies Research (5 papers), Protein purification and stability (4 papers), Viral Infectious Diseases and Gene Expression in Insects (4 papers) and Cholinesterase and Neurodegenerative Diseases (4 papers). The work is most often cited by research in Physiology (916 citations), Aging (34 citations), Biomaterials (221 citations), Computational Theory and Mathematics (233 citations) and Molecular Biology (929 citations). Sean Chia has collaborated with scholars based in United Kingdom, Sweden and Singapore. Frequent co-authors include Michele Vendruscolo, Johnny Habchi, Tuomas P. J. Knowles, Christopher M. Dobson, Sara Linse, Francesco Simone Ruggeri, Thomas C. T. Michaels, Samuel I. A. Cohen, Michele Perni and Georg Meisl. Their work appears in journals such as ACS Chemical Neuroscience, Communications Biology, Proceedings of the National Academy of Sciences, Science Advances and Biophysical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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