Roberta Cascella

5.0k total citations · 3 hit papers
57 papers, 3.3k citations indexed

About

Roberta Cascella is a scholar working on Physiology, Molecular Biology and Neurology. According to data from OpenAlex, Roberta Cascella has authored 57 papers receiving a total of 3.3k indexed citations (citations by other indexed papers that have themselves been cited), including 41 papers in Physiology, 35 papers in Molecular Biology and 16 papers in Neurology. Recurrent topics in Roberta Cascella's work include Alzheimer's disease research and treatments (41 papers), Parkinson's Disease Mechanisms and Treatments (13 papers) and Prion Diseases and Protein Misfolding (10 papers). Roberta Cascella is often cited by papers focused on Alzheimer's disease research and treatments (41 papers), Parkinson's Disease Mechanisms and Treatments (13 papers) and Prion Diseases and Protein Misfolding (10 papers). Roberta Cascella collaborates with scholars based in Italy, United Kingdom and Spain. Roberta Cascella's co-authors include Cristina Cecchi, Fabrizio Chiti, Christopher M. Dobson, Giovanna Cenini, Ana Lloret, Nunilo Cremades, Serene W. Chen, Alessandra Bigi, Michele Vendruscolo and Elisa Evangelisti and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Roberta Cascella

57 papers receiving 3.3k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers

2017 520 citations Giuliana Fusco, Serene W. Chen et al. Science profile →
Oxidative Stress in Neurodegenerative Diseases: From a Mitochondrial Point of View

2019 372 citations Giovanna Cenini, Roberta Cascella et al. profile →
The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells

2021 166 citations Roberta Cascella, Serene W. Chen et al. Nature Communications profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Roberta Cascella	1.7k	1.6k	841	397	365	57	3.3k
Cristina Cecchi	2.4k 1.4×	2.4k 1.4×	889 1.1×	505 1.3×	533 1.5×	97	4.3k
Barry Boland	1.2k 0.7×	1.5k 0.9×	396 0.5×	416 1.0×	626 1.7×	26	3.0k
Nichole E. LaPointe	1.5k 0.9×	1.7k 1.0×	394 0.5×	713 1.8×	509 1.4×	32	2.9k
Annett Boeddrich	1.6k 0.9×	1.2k 0.7×	514 0.6×	842 2.1×	335 0.9×	14	2.7k
Frits Kamp	2.3k 1.3×	1.3k 0.8×	1.1k 1.3×	614 1.5×	465 1.3×	58	4.0k
Anna Pensalfini	1.9k 1.1×	2.4k 1.4×	234 0.3×	371 0.9×	458 1.3×	31	3.5k
Mihaela Necula	1.2k 0.7×	1.9k 1.2×	313 0.4×	404 1.0×	197 0.5×	19	2.4k
Cristina Carvalho	1.7k 1.0×	1.5k 0.9×	248 0.3×	421 1.1×	204 0.6×	61	4.2k
Alejandra del C. Alonso	1.6k 1.0×	2.6k 1.6×	386 0.5×	915 2.3×	522 1.4×	35	3.9k
Yvonne S. Eisele	1.4k 0.8×	1.5k 0.9×	348 0.4×	299 0.8×	156 0.4×	30	2.3k

Countries citing papers authored by Roberta Cascella

Since Specialization

Citations

This map shows the geographic impact of Roberta Cascella's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roberta Cascella with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roberta Cascella more than expected).

Fields of papers citing papers by Roberta Cascella

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roberta Cascella. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roberta Cascella. The network helps show where Roberta Cascella may publish in the future.

Co-authorship network of co-authors of Roberta Cascella

This figure shows the co-authorship network connecting the top 25 collaborators of Roberta Cascella. A scholar is included among the top collaborators of Roberta Cascella based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Roberta Cascella. Roberta Cascella is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bigi, Alessandra, Devkee M. Vadukul, Fabrizio Chiti, et al.. (2024). A single-domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer’s disease CSF. Alzheimer s Research & Therapy. 16(1). 13–13. 7 indexed citations

Limbocker, Ryan, Nunilo Cremades, Roberta Cascella, et al.. (2023). Characterization of Pairs of Toxic and Nontoxic Misfolded Protein Oligomers Elucidates the Structural Determinants of Oligomer Toxicity in Protein Misfolding Diseases. Accounts of Chemical Research. 56(12). 1395–1405. 31 indexed citations

Bigi, Alessandra, Roberta Cascella, & Cristina Cecchi. (2023). α-Synuclein oligomers and fibrils: partners in crime in synucleinopathies. Neural Regeneration Research. 18(11). 2332–2342. 11 indexed citations

Cascella, Roberta, Alessandra Bigi, Maria Cristina Gagliani, et al.. (2022). A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43. Science Advances. 8(30). eabm6376–eabm6376. 16 indexed citations

Cascella, Roberta, Martina Banchelli, Seyyed Abolghasem Ghadami, et al.. (2022). An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature. Annals of Medicine. 55(1). 72–88. 4 indexed citations

Bigi, Alessandra, Roberta Cascella, Caterina Bernacchioni, et al.. (2022). Sphingosine 1‐phosphate attenuates neuronal dysfunction induced by amyloid‐β oligomers through endocytic internalization of NMDA receptors. FEBS Journal. 290(1). 112–133. 5 indexed citations

Cascella, Roberta, et al.. (2022). Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species. Cellular and Molecular Life Sciences. 79(9). 500–500. 19 indexed citations

Cascella, Roberta, Alessandra Bigi, Nunilo Cremades, & Cristina Cecchi. (2022). Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies. Cellular and Molecular Life Sciences. 79(3). 174–174. 72 indexed citations

Cascella, Roberta, Serene W. Chen, Alessandra Bigi, et al.. (2021). The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells. Nature Communications. 12(1). 1814–1814. 166 indexed citations breakdown →

10.

Bigi, Alessandra, et al.. (2021). Exploring the Release of Toxic Oligomers from α-Synuclein Fibrils with Antibodies and STED Microscopy. Life. 11(5). 431–431. 21 indexed citations

11.

Limbocker, Ryan, Benedetta Mannini, Sean Chia, et al.. (2018). Modulating Amyloid-Beta Aggregation to Reduce the Toxicity of its Oligomeric Aggregates. Biophysical Journal. 114(3). 430a–430a. 1 indexed citations

12.

Fusco, Giuliana, Serene W. Chen, Philip T. F. Williamson, et al.. (2017). Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers. Science. 358(6369). 1440–1443. 520 indexed citations breakdown →

13.

Evangelisti, Elisa, Roberta Cascella, Matteo Becatti, et al.. (2016). Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases. Scientific Reports. 6(1). 32721–32721. 97 indexed citations

14.

Calamai, Martino, Elisa Evangelisti, Roberta Cascella, et al.. (2015). Single molecule experiments emphasize GM1 as a key player of the different cytotoxicity of structurally distinct Aβ1–42 oligomers. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1858(2). 386–392. 22 indexed citations

15.

Natale, Concetta Di, Pasqualina Liana Scognamiglio, Roberta Cascella, et al.. (2015). Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions. The FASEB Journal. 29(9). 3689–3701. 56 indexed citations

16.

Cascella, Roberta, Elisa Evangelisti, Mariagioia Zampagni, et al.. (2014). S-linolenoyl glutathione intake extends life-span and stress resistance via Sir-2.1 upregulation in Caenorhabditis elegans. Free Radical Biology and Medicine. 73. 127–135. 22 indexed citations

17.

Cascella, Roberta, Simona Conti, Francesca Tatini, et al.. (2013). Extracellular chaperones prevent Aβ42-induced toxicity in rat brains. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1832(8). 1217–1226. 52 indexed citations

18.

Matteini, Paolo, Giuliano Giambastiani, Francesca Tatini, et al.. (2012). Light-responsive nanocomposite sponges for on demand chemical release with high spatial and dosage control. Journal of Materials Chemistry B. 1(8). 1096–1096. 21 indexed citations

19.

Zampagni, Mariagioia, Roberta Cascella, Fiorella Casamenti, et al.. (2010). A comparison of the biochemical modifications caused by toxic and non‐toxic protein oligomers in cells. Journal of Cellular and Molecular Medicine. 15(10). 2106–2116. 50 indexed citations

20.

Zampagni, Mariagioia, Elisa Evangelisti, Roberta Cascella, et al.. (2010). Lipid rafts are primary mediators of amyloid oxidative attack on plasma membrane. Journal of Molecular Medicine. 88(6). 597–608. 38 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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