Roberta Cascella

5.0k total citations · 3 hit papers
57 papers, 3.3k citations indexed

About

Roberta Cascella is a scholar working on Physiology, Molecular Biology and Neurology. According to data from OpenAlex, Roberta Cascella has authored 57 papers receiving a total of 3.3k indexed citations (citations by other indexed papers that have themselves been cited), including 41 papers in Physiology, 35 papers in Molecular Biology and 16 papers in Neurology. Recurrent topics in Roberta Cascella's work include Alzheimer's disease research and treatments (41 papers), Parkinson's Disease Mechanisms and Treatments (13 papers) and Prion Diseases and Protein Misfolding (10 papers). Roberta Cascella is often cited by papers focused on Alzheimer's disease research and treatments (41 papers), Parkinson's Disease Mechanisms and Treatments (13 papers) and Prion Diseases and Protein Misfolding (10 papers). Roberta Cascella collaborates with scholars based in Italy, United Kingdom and Spain. Roberta Cascella's co-authors include Cristina Cecchi, Fabrizio Chiti, Christopher M. Dobson, Giovanna Cenini, Ana Lloret, Nunilo Cremades, Serene W. Chen, Alessandra Bigi, Michele Vendruscolo and Elisa Evangelisti and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Roberta Cascella

57 papers receiving 3.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers

2017 520 citations Giuliana Fusco, Serene W. Chen et al. Science profile →
Oxidative Stress in Neurodegenerative Diseases: From a Mitochondrial Point of View

2019 372 citations Roberta Cascella et al. profile →
The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells

2021 166 citations Roberta Cascella, Serene W. Chen et al. Nature Communications profile →

Peers

Countries citing papers authored by Roberta Cascella

Since Specialization

Citations

This map shows the geographic impact of Roberta Cascella's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roberta Cascella with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roberta Cascella more than expected).

Fields of papers citing papers by Roberta Cascella

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roberta Cascella. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roberta Cascella. The network helps show where Roberta Cascella may publish in the future.

Co-authorship network of co-authors of Roberta Cascella

This figure shows the co-authorship network connecting the top 25 collaborators of Roberta Cascella. A scholar is included among the top collaborators of Roberta Cascella based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Roberta Cascella. Roberta Cascella is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A single-domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer’s disease CSF 2024 ·Alzheimer s Research & Therapy ·Alessandra Bigi, (unknown), Devkee M. Vadukul, Fabrizio Chiti, Cristina Cecchi, Francesco A. Aprile, Roberta Cascella	7
2	Exploring the Aβ1-42 fibrillogenesis timeline by atomic force microscopy and surface enhanced Raman spectroscopy 2024 ·Frontiers in Molecular Biosciences ·(unknown), Cristiano D’Andrea, Martina Banchelli, (unknown), Roberta Cascella, Marella de Angelis, Paolo Matteini	3
3	Characterization of Pairs of Toxic and Nontoxic Misfolded Protein Oligomers Elucidates the Structural Determinants of Oligomer Toxicity in Protein Misfolding Diseases 2023 ·Accounts of Chemical Research ·Ryan Limbocker, Nunilo Cremades, Roberta Cascella, Peter M. Tessier, Michele Vendruscolo, Fabrizio Chiti	31
4	α-Synuclein oligomers and fibrils: partners in crime in synucleinopathies 2023 ·Neural Regeneration Research ·Alessandra Bigi, Roberta Cascella, Cristina Cecchi	11
5	A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43 2022 ·Science Advances ·Roberta Cascella, Alessandra Bigi, (unknown), Maria Cristina Gagliani, (unknown), (unknown), Katia Cortese, Cristina Cecchi, Fabrizio Chiti	16
6	An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature 2022 ·Annals of Medicine ·Roberta Cascella, Martina Banchelli, Seyyed Abolghasem Ghadami, Diletta Ami, Maria Cristina Gagliani, Alessandra Bigi, (unknown), Davide Tampellini, Katia Cortese, Cristina Cecchi, Antonino Natalello, Hadi Adibi, Paolo Matteini, Fabrizio Chiti	4
7	Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species 2022 ·Cellular and Molecular Life Sciences ·(unknown), (unknown), Roberta Cascella, Cristina Cecchi, Michele Vendruscolo, Fabrizio Chiti	19
8	Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies 2022 ·Cellular and Molecular Life Sciences ·Roberta Cascella, Alessandra Bigi, Nunilo Cremades, Cristina Cecchi	72
9	Exploring the Release of Toxic Oligomers from α-Synuclein Fibrils with Antibodies and STED Microscopy 2021 ·Life ·Alessandra Bigi, (unknown), Serene W. Chen, Roberta Cascella, Cristina Cecchi	21
10	The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells breakdown → 2021 ·Nature Communications ·Roberta Cascella, Serene W. Chen, Alessandra Bigi, José D. Camino, Catherine K. Xu, Christopher M. Dobson, Fabrizio Chiti, Nunilo Cremades, Cristina Cecchi	166
11	Modulating Amyloid-Beta Aggregation to Reduce the Toxicity of its Oligomeric Aggregates 2018 ·Biophysical Journal ·Ryan Limbocker, Benedetta Mannini, Sean Chia, Francesco Simone Ruggeri, Michele Perni, Roberta Cascella, Catherine K. Xu, Johnny Habchi, Janet R. Kumita, Fabrizio Chiti, Tuomas P. J. Knowles, Michele Vendruscolo, Christopher M. Dobson	1
12	Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers breakdown → 2017 ·Science ·Giuliana Fusco, Serene W. Chen, Philip T. F. Williamson, Roberta Cascella, Michele Perni, James A. Jarvis, Cristina Cecchi, Michele Vendruscolo, Fabrizio Chiti, Nunilo Cremades, Liming Ying, Christopher M. Dobson, Alfonso De Simone	520
13	Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases 2016 ·Scientific Reports ·Elisa Evangelisti, Roberta Cascella, Matteo Becatti, Giovanna Marrazza, Christopher M. Dobson, Fabrizio Chiti, Massimo Stefani, Cristina Cecchi	97
14	Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies 2016 ·Journal of Biological Chemistry ·Roberta Cascella, Claudia Capitini, (unknown), Christopher M. Dobson, Cristina Cecchi, Fabrizio Chiti	67
15	Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions 2015 ·The FASEB Journal ·Concetta Di Natale, Pasqualina Liana Scognamiglio, Roberta Cascella, Cristina Cecchi, Anna Russo, Marilisa Leone, Amanda Penco, Annalisa Relini, Luca Federici, Adele Di Matteo, Fabrizio Chiti, Luigi Vitagliano, Daniela Marasco	56
16	Single molecule experiments emphasize GM1 as a key player of the different cytotoxicity of structurally distinct Aβ1–42 oligomers 2015 ·Biochimica et Biophysica Acta (BBA) - Biomembranes ·Martino Calamai, Elisa Evangelisti, Roberta Cascella, (unknown), Cristina Cecchi, Massimo Stefani, Francesco S. Pavone	22
17	Extracellular chaperones prevent Aβ42-induced toxicity in rat brains 2013 ·Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Roberta Cascella, Simona Conti, Francesca Tatini, Elisa Evangelisti, Tania Scartabelli, Fiorella Casamenti, Mark R. Wilson, Fabrizio Chiti, Cristina Cecchi	52
18	Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro 2013 ·Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Roberta Cascella, Simona Conti, Benedetta Mannini, Xinyi Li, Joel N. Buxbaum, Bruno Tiribilli, Fabrizio Chiti, Cristina Cecchi	67
19	Allele specific Taqman-based real-time PCR assay to quantify circulating BRAFV600E mutated DNA in plasma of melanoma patients 2010 ·Clinica Chimica Acta ·Pamela Pinzani, Francesca Salvianti, Roberta Cascella, Daniela Massi, Vincenzo De Giorgi, Mario Pazzagli, Claudio Orlando	50
20	A comparison of the biochemical modifications caused by toxic and non‐toxic protein oligomers in cells 2010 ·Journal of Cellular and Molecular Medicine ·Mariagioia Zampagni, Roberta Cascella, Fiorella Casamenti, Cristina Grossi, Elisa Evangelisti, Daniel Wright, Matteo Becatti, Gianfranco Liguri, Benedetta Mannini, Silvia Campioni, Fabrizio Chiti, Cristina Cecchi	50

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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