Christopher B. Newgard

65.7k total citations · 17 hit papers
397 papers, 44.6k citations indexed

About

Christopher B. Newgard is a scholar working on Molecular Biology, Surgery and Physiology. According to data from OpenAlex, Christopher B. Newgard has authored 397 papers receiving a total of 44.6k indexed citations (citations by other indexed papers that have themselves been cited), including 227 papers in Molecular Biology, 170 papers in Surgery and 155 papers in Physiology. Recurrent topics in Christopher B. Newgard's work include Pancreatic function and diabetes (158 papers), Adipose Tissue and Metabolism (103 papers) and Metabolism, Diabetes, and Cancer (89 papers). Christopher B. Newgard is often cited by papers focused on Pancreatic function and diabetes (158 papers), Adipose Tissue and Metabolism (103 papers) and Metabolism, Diabetes, and Cancer (89 papers). Christopher B. Newgard collaborates with scholars based in United States, Canada and Spain. Christopher B. Newgard's co-authors include Olga Ilkayeva, James R. Bain, Deborah M. Muoio, Michael J. Muehlbauer, Robert D. Stevens, Svati H. Shah, Roger H. Unger, Julie McGarry, Hans E. Hohmeier and Brett R. Wenner and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Christopher B. Newgard

392 papers receiving 43.9k citations

Hit Papers

A Branched-Chain Amino Ac... 1994 2026 2004 2015 2009 2008 2001 2010 2012 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
    2009 2.4k citations Christopher B. Newgard, Jie An et al. profile →
  2. Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance
    2008 1.6k citations Dorothy H. Slentz, Olga Ilkayeva et al. profile →
  3. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
    2001 1.5k citations Christopher B. Newgard et al. profile →
  4. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
    2010 1.4k citations Matthew D. Hirschey, Tadahiro Shimazu et al. profile →
  5. Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
    2012 1.3k citations Tadahiro Shimazu, Matthew D. Hirschey et al. Science profile →
  6. Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
    2008 920 citations Deborah M. Muoio, Christopher B. Newgard Nature Reviews Molecular Cell Biology profile →
  7. Interplay between Lipids and Branched-Chain Amino Acids in Development of Insulin Resistance
    2012 827 citations Christopher B. Newgard profile →
  8. Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion.
    2000 760 citations Hans E. Hohmeier, Christopher B. Newgard et al. Diabetes profile →
  9. Direct antidiabetic effect of leptin through triglyceride depletion of tissues
    1997 567 citations May-Yun Wang, Christopher B. Newgard et al. Proceedings of the National Academy of Sciences profile →
  10. Metabolomics and Metabolic Diseases: Where Do We Stand?
    2016 544 citations Christopher B. Newgard profile →
  11. Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children
    2016 542 citations Michael J. Barratt, Bernard Henrissat et al. Science profile →
  12. Chapter 8 Use of Recombinant Adenovirus for Metabolic Engineering of Mammalian Cells
    1994 528 citations Thomas Becker, Richard J. Noel et al. Methods in cell biology profile →
  13. Hyperlipidemic Effects of Dietary Saturated Fats Mediated through PGC-1β Coactivation of SREBP
    2005 513 citations Christopher B. Newgard et al. profile →
  14. Circadian Clock NAD + Cycle Drives Mitochondrial Oxidative Metabolism in Mice
    2013 507 citations Clara Bien Peek, Kathryn Moynihan Ramsey et al. Science profile →
  15. Cafeteria Diet Is a Robust Model of Human Metabolic Syndrome With Liver and Adipose Inflammation: Comparison to High‐Fat Diet
    2011 464 citations Michael J. Muehlbauer, Christopher B. Newgard et al. Obesity profile →
  16. Mechanisms controlling pancreatic islet cell function in insulin secretion
    2021 380 citations Jonathan E. Campbell, Christopher B. Newgard Nature Reviews Molecular Cell Biology profile →
  17. Insulin action, type 2 diabetes, and branched-chain amino acids: A two-way street
    2021 183 citations Phillip J. White, Robert W. McGarrah et al. Molecular Metabolism profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Christopher B. Newgard 24.1k 17.5k 11.2k 7.4k 7.1k 397 44.6k
Morris F. White 32.8k 1.4× 11.5k 0.7× 12.4k 1.1× 6.5k 0.9× 10.6k 1.5× 346 51.4k
Takashi Kadowaki 25.1k 1.0× 16.3k 0.9× 10.4k 0.9× 17.1k 2.3× 14.1k 2.0× 869 62.0k
Oluf Pedersen 18.3k 0.8× 11.7k 0.7× 9.4k 0.8× 5.1k 0.7× 12.9k 1.8× 707 43.8k
Barbara B. Kahn 23.8k 1.0× 19.7k 1.1× 7.9k 0.7× 12.4k 1.7× 6.7k 0.9× 251 46.7k
Morris J. Birnbaum 27.6k 1.1× 9.9k 0.6× 8.3k 0.7× 5.7k 0.8× 5.0k 0.7× 243 41.3k
Ryozo Nagai 18.1k 0.8× 8.1k 0.5× 7.4k 0.7× 8.8k 1.2× 3.5k 0.5× 859 45.6k
Philippe Froguel 13.2k 0.5× 10.7k 0.6× 10.0k 0.9× 8.7k 1.2× 7.2k 1.0× 529 37.3k
Alan R. Saltiel 25.3k 1.0× 11.2k 0.6× 5.8k 0.5× 9.4k 1.3× 4.9k 0.7× 280 45.5k
C. Ronald Kahn 36.9k 1.5× 26.6k 1.5× 14.4k 1.3× 13.6k 1.8× 13.9k 2.0× 515 74.9k
Ralph A. DeFronzo 21.0k 0.9× 17.7k 1.0× 12.0k 1.1× 9.1k 1.2× 24.6k 3.5× 427 52.3k

Countries citing papers authored by Christopher B. Newgard

Since Specialization
Citations

This map shows the geographic impact of Christopher B. Newgard's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher B. Newgard with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher B. Newgard more than expected).

Fields of papers citing papers by Christopher B. Newgard

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher B. Newgard. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher B. Newgard. The network helps show where Christopher B. Newgard may publish in the future.

Co-authorship network of co-authors of Christopher B. Newgard

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher B. Newgard. A scholar is included among the top collaborators of Christopher B. Newgard based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher B. Newgard. Christopher B. Newgard is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Rowland, Leslie A., Adı́lson Guilherme, Felipe Henriques, et al.. (2023). De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics. Nature Communications. 14(1). 1362–1362. 28 indexed citations
2.
Poon, Raymond, Puviindran Nadesan, Makoto Nakagawa, et al.. (2023). Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation. Cell Reports. 42(6). 112578–112578. 13 indexed citations
3.
Regan, Jessica A., Robert J. Mentz, Jennifer B. Green, et al.. (2023). Mitochondrial metabolites predict adverse cardiovascular events in individuals with diabetes. JCI Insight. 8(17). 9 indexed citations
4.
Hernández‐Saavedra, Diego, Christina A. Markunas, Hirokazu Takahashi, et al.. (2022). Maternal Exercise and Paternal Exercise Induce Distinct Metabolite Signatures in Offspring Tissues. Diabetes. 71(10). 2094–2105. 10 indexed citations
5.
Fan, Liyan, David R. Sweet, Domenick A. Prosdocimo, et al.. (2021). Muscle Krüppel-like factor 15 regulates lipid flux and systemic metabolic homeostasis. Journal of Clinical Investigation. 131(4). 20 indexed citations
6.
Liu, Yu, Alan Kuang, James R. Bain, et al.. (2021). Maternal Metabolites Associated With Gestational Diabetes Mellitus and a Postpartum Disorder of Glucose Metabolism. The Journal of Clinical Endocrinology & Metabolism. 106(11). 3283–3294. 17 indexed citations
7.
Chang, Hao-Wei, Nathan P. McNulty, Martin L. Hibberd, et al.. (2021). Gut microbiome contributions to altered metabolism in a pig model of undernutrition. Proceedings of the National Academy of Sciences. 118(21). 18 indexed citations
8.
Campbell, Jonathan E. & Christopher B. Newgard. (2021). Mechanisms controlling pancreatic islet cell function in insulin secretion. Nature Reviews Molecular Cell Biology. 22(2). 142–158. 380 indexed citations breakdown →
9.
Levine, Daniel C., Hee‐Kyung Hong, Jonathan Cedernaes, et al.. (2021). NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding. Nature Metabolism. 3(12). 1621–1632. 50 indexed citations
10.
Liu, Yu, Alan Kuang, Octavious Talbot, et al.. (2020). Metabolomic and genetic associations with insulin resistance in pregnancy. Diabetologia. 63(9). 1783–1795. 32 indexed citations
11.
Hohmeier, Hans E., Lu Zhang, Brandon L. Taylor, et al.. (2020). Identification of a small molecule that stimulates human β-cell proliferation and insulin secretion, and protects against cytotoxic stress in rat insulinoma cells. PLoS ONE. 15(3). e0224344–e0224344. 19 indexed citations
12.
Haldeman, Jonathan M., Amanda E. Conway, Michelle Arlotto, et al.. (2018). Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing. Nucleic Acids Research. 47(4). e23–e23. 23 indexed citations
13.
Chondronikola, Maria, Faidon Magkos, Jun Yoshino, et al.. (2018). Effect of Progressive Weight Loss on Lactate Metabolism: A Randomized Controlled Trial. Obesity. 26(4). 683–688. 18 indexed citations
14.
Lowe, William L., James R. Bain, Michael Nodzenski, et al.. (2017). Maternal BMI and Glycemia Impact the Fetal Metabolome. Diabetes Care. 40(7). 902–910. 83 indexed citations
15.
Jensen, Mette V., Jessica Gooding, Mourad Ferdaoussi, et al.. (2017). Metabolomics applied to islet nutrient sensing mechanisms. Diabetes Obesity and Metabolism. 19(S1). 90–94. 16 indexed citations
16.
White, Phillip J., Amanda L. Lapworth, Jie An, et al.. (2016). Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export. Molecular Metabolism. 5(7). 538–551. 202 indexed citations
17.
Shimazu, Tadahiro, Matthew D. Hirschey, John C. Newman, et al.. (2012). Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor. Science. 339(6116). 211–214. 1329 indexed citations breakdown →
18.
Wang, May-Yun, Lijun Chen, Gregory O. Clark, et al.. (2010). Leptin therapy in insulin-deficient type I diabetes. Proceedings of the National Academy of Sciences. 107(11). 4813–4819. 262 indexed citations
19.
Chopra, Atul R., Jean‐François Louet, Pradip Saha, et al.. (2008). Absence of the SRC-2 Coactivator Results in a Glycogenopathy Resembling Von Gierke's Disease. Science. 322(5906). 1395–1399. 133 indexed citations
20.
Becker, Thomas, Richard J. Noel, Ward Coats, et al.. (1994). Chapter 8 Use of Recombinant Adenovirus for Metabolic Engineering of Mammalian Cells. Methods in cell biology. 43 Pt A. 161–189. 528 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Morris F. White Breakdown of academic impact, for papers by Takashi Kadowaki Breakdown of academic impact, for papers by Oluf Pedersen Breakdown of academic impact, for papers by Barbara B. Kahn Breakdown of academic impact, for papers by Morris J. Birnbaum Breakdown of academic impact, for papers by Ryozo Nagai Breakdown of academic impact, for papers by Philippe Froguel Breakdown of academic impact, for papers by Alan R. Saltiel Breakdown of academic impact, for papers by C. Ronald Kahn Breakdown of academic impact, for papers by Ralph A. DeFronzo
Rankless by CCL
2026