Saul J. Karpen

16.5k total citations · 6 hit papers
172 papers, 9.1k citations indexed

About

Saul J. Karpen is a scholar working on Surgery, Oncology and Epidemiology. According to data from OpenAlex, Saul J. Karpen has authored 172 papers receiving a total of 9.1k indexed citations (citations by other indexed papers that have themselves been cited), including 106 papers in Surgery, 67 papers in Oncology and 50 papers in Epidemiology. Recurrent topics in Saul J. Karpen's work include Pediatric Hepatobiliary Diseases and Treatments (69 papers), Drug Transport and Resistance Mechanisms (58 papers) and Liver Disease Diagnosis and Treatment (40 papers). Saul J. Karpen is often cited by papers focused on Pediatric Hepatobiliary Diseases and Treatments (69 papers), Drug Transport and Resistance Mechanisms (58 papers) and Liver Disease Diagnosis and Treatment (40 papers). Saul J. Karpen collaborates with scholars based in United States, Canada and United Kingdom. Saul J. Karpen's co-authors include Paul A. Dawson, Marco Arrese, Astrid Kosters, Tracy L. Zimmerman, Michael Trauner, Barbara O. McElhanon, Courtney McCracken, William G. Sharp, Miriam B. Vos and Jean A. Welsh and has published in prestigious journals such as Science, Journal of Biological Chemistry and Circulation.

In The Last Decade

Saul J. Karpen

170 papers receiving 8.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Gastrointestinal Symptoms in Autism Spectrum Disorder: A Meta-analysis

2014 564 citations Barbara O. McElhanon, Courtney McCracken et al. PEDIATRICS profile →
Bile acids and nonalcoholic fatty liver disease

2016 478 citations Saul J. Karpen, Paul A. Dawson et al. Hepatology profile →
Intestinal transport and metabolism of bile acids

2014 430 citations Paul A. Dawson, Saul J. Karpen profile →
Increasing Prevalence of Nonalcoholic Fatty Liver Disease Among United States Adolescents, 1988-1994 to 2007-2010

2012 370 citations Saul J. Karpen et al. The Journal of Pediatrics profile →
Guideline for the Evaluation of Cholestatic Jaundice in Infants

2016 296 citations Saul J. Karpen et al. Journal of Pediatric Gastroenterology and Nutrition profile →
Biliary Atresia: Clinical and Research Challenges for the Twenty‐First Century

2018 218 citations Jorge A. Bezerra, Saul J. Karpen et al. Hepatology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Saul J. Karpen United States	53	4.0k	2.8k	2.7k	1.9k	1.9k	172	9.1k
Henkjan J. Verkade Netherlands	48	3.3k 0.8×	1.8k 0.6×	1.7k 0.6×	1.8k 1.0×	1.2k 0.6×	311	8.1k
Antonio Moschetta Italy	56	5.0k 1.2×	3.9k 1.4×	4.9k 1.8×	5.4k 2.9×	1.3k 0.7×	202	13.8k
Giuseppe Palasciano Italy	39	2.2k 0.6×	1.5k 0.5×	1.0k 0.4×	1.2k 0.7×	719 0.4×	178	5.6k
Yukihiko Adachi Japan	42	946 0.2×	1.5k 0.5×	865 0.3×	1.4k 0.7×	871 0.5×	205	6.3k
Christopher J. Sinal Canada	43	2.0k 0.5×	3.1k 1.1×	3.2k 1.2×	2.6k 1.4×	428 0.2×	85	9.0k
Stergios A. Pοlyzos Greece	51	2.3k 0.6×	5.0k 1.8×	1.5k 0.6×	2.4k 1.3×	1.1k 0.6×	301	10.9k
Guido N.J. Tytgat Netherlands	54	6.8k 1.7×	1.6k 0.6×	2.2k 0.8×	1.6k 0.8×	329 0.2×	199	11.3k
Julian R.F. Walters United Kingdom	44	2.4k 0.6×	1.5k 0.5×	948 0.3×	1.3k 0.7×	414 0.2×	157	6.2k
Jan B.�M.�J. Jansen Netherlands	52	4.8k 1.2×	1.5k 0.5×	2.3k 0.9×	1.5k 0.8×	188 0.1×	349	10.6k
Goro Kajiyama Japan	53	4.1k 1.0×	904 0.3×	2.1k 0.8×	2.0k 1.1×	365 0.2×	434	10.0k

Countries citing papers authored by Saul J. Karpen

Since Specialization

Citations

This map shows the geographic impact of Saul J. Karpen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Saul J. Karpen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Saul J. Karpen more than expected).

Fields of papers citing papers by Saul J. Karpen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Saul J. Karpen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Saul J. Karpen. The network helps show where Saul J. Karpen may publish in the future.

Co-authorship network of co-authors of Saul J. Karpen

This figure shows the co-authorship network connecting the top 25 collaborators of Saul J. Karpen. A scholar is included among the top collaborators of Saul J. Karpen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Saul J. Karpen. Saul J. Karpen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ghallab, Ahmed, Mattias Mandorfer, Guido Stirnimann, et al.. (2025). Enteronephrohepatic circulation of bile acids and therapeutic potential of systemic bile acid transporter inhibitors. Journal of Hepatology. 83(5). 1204–1217. 3 indexed citations

Loomba, Rohit, Virginia Clark, Mattias Mandorfer, et al.. (2025). Multi-Society Expert Panel Consensus Guidance Regarding Clinical Assessment and Clinical Trial Endpoints in Adults With Alpha-1 Antitrypsin Deficiency–Associated Liver Disease. Gastroenterology. 170(4). 829–842.

Fay, Meredith E., Ashley Bennett, Kimberly Pachura, et al.. (2024). BiliQML: a supervised machine-learning model to quantify biliary forms from digitized whole slide liver histopathological images. American Journal of Physiology-Gastrointestinal and Liver Physiology. 327(1). G1–G15. 2 indexed citations

Shen, Luyao, et al.. (2023). Opportunities and considerations for studying liver disease with microphysiological systems on a chip. Lab on a Chip. 23(13). 2877–2898. 8 indexed citations

Karpen, Saul J., et al.. (2023). Genetic Contributions to Biliary Atresia: A Developmental Cholangiopathy. Seminars in Liver Disease. 43(3). 323–335. 7 indexed citations

Bennett, Ashley, Sudarshan Malla, Caroline Klindt, et al.. (2023). Liver-restricted deletion of the biliary atresia candidate gene Pkd1l1 causes bile duct dysmorphogenesis and ciliopathy. Hepatology. 77(4). 1274–1286. 18 indexed citations

Wilkins, Benjamin J., et al.. (2023). Loss of zebrafish pkd1l1 causes biliary defects that have implications for biliary atresia splenic malformation. Disease Models & Mechanisms. 16(10). 4 indexed citations

Karpen, Saul J.. (2018). Novel Bile Acid Therapies for Liver Disease.. PubMed Central. 14(2). 117–119. 2 indexed citations

Desai, Moreshwar S., Hernán Vásquez, Heinrich Taegtmeyer, et al.. (2016). Bile acid excess induces cardiomyopathy and metabolic dysfunctions in the heart. Hepatology. 65(1). 189–201. 104 indexed citations

10.

Kamath, Binita M., Zhen Chen, René Romero, et al.. (2015). Quality of Life and Its Determinants in a Multicenter Cohort of Children with Alagille Syndrome. The Journal of Pediatrics. 167(2). 390–396.e3. 18 indexed citations

11.

Karpen, Saul J., et al.. (2015). Genetic Contributors and Modifiers of Biliary Atresia. Digestive Diseases. 33(3). 408–414. 32 indexed citations

12.

McElhanon, Barbara O., Courtney McCracken, Saul J. Karpen, & William G. Sharp. (2014). Gastrointestinal Symptoms in Autism Spectrum Disorder: A Meta-analysis. PEDIATRICS. 133(5). 872–883. 564 indexed citations breakdown →

13.

Desai, Moreshwar S., et al.. (2014). Abstract 18219: TGR5 - a Novel Membrane Receptor for Bile Acids Regulates Myocardial Response to Exercise, Catecholamine and Pressure Overload Induced Stress. Circulation. 130. 2 indexed citations

14.

Kelly, Déirdre, John C. Bucuvalas, Estella M. Alonso, et al.. (2013). Long-term medical management of the pediatric patient after liver transplantation: 2013 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation. Liver Transplantation. 19(8). 798–825. 106 indexed citations

15.

Shneider, Benjamin L., John Magee, Jorge A. Bezerra, et al.. (2012). Efficacy of Fat-Soluble Vitamin Supplementation in Infants With Biliary Atresia. PEDIATRICS. 130(3). e607–e614. 66 indexed citations

16.

Harpavat, Sanjiv, Milton J. Finegold, & Saul J. Karpen. (2011). Patients With Biliary Atresia Have Elevated Direct/Conjugated Bilirubin Levels Shortly After Birth. PEDIATRICS. 128(6). e1428–e1433. 127 indexed citations

17.

Chopra, Atul R., Jean‐François Louet, Pradip Saha, et al.. (2008). Absence of the SRC-2 Coactivator Results in a Glycogenopathy Resembling Von Gierke's Disease. Science. 322(5906). 1395–1399. 133 indexed citations

18.

Lee, Timothy C., Neal R. Barshes, Christine A. O’Mahony, et al.. (2006). Resolution of medically resistant hypothyroidism after liver transplantation for hepatic hemangioendothelioma. Journal of Pediatric Surgery. 41(10). 1783–1785. 18 indexed citations

19.

Chang, I‐Fen, et al.. (2004). P0096 PP POST‐TRANSPLANT LYMPHOPROLIFERATIVE DISEASE IN PEDIATRIC LIVER TRANSPLANT RECIPIENTS TREATED WITH ANTI‐CD20 MONOCLONAL ANTIBODY: A LONG‐TERM OUTCOME STUDY. Journal of Pediatric Gastroenterology and Nutrition. 39(S1). 1 indexed citations

20.

Denson, Lee A., et al.. (2000). Interleukin-1β Suppresses Retinoid Transactivation of Two Hepatic Transporter Genes Involved in Bile Formation. Journal of Biological Chemistry. 275(12). 8835–8843. 139 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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