Samuel Klein

71.3k total citations · 26 hit papers
383 papers, 48.5k citations indexed

About

Samuel Klein is a scholar working on Physiology, Endocrinology, Diabetes and Metabolism and Epidemiology. According to data from OpenAlex, Samuel Klein has authored 383 papers receiving a total of 48.5k indexed citations (citations by other indexed papers that have themselves been cited), including 218 papers in Physiology, 98 papers in Endocrinology, Diabetes and Metabolism and 86 papers in Epidemiology. Recurrent topics in Samuel Klein's work include Diet and metabolism studies (129 papers), Adipose Tissue and Metabolism (93 papers) and Muscle metabolism and nutrition (62 papers). Samuel Klein is often cited by papers focused on Diet and metabolism studies (129 papers), Adipose Tissue and Metabolism (93 papers) and Muscle metabolism and nutrition (62 papers). Samuel Klein collaborates with scholars based in United States, Italy and Greece. Samuel Klein's co-authors include Jeffrey I. Gordon, Peter J. Turnbaugh, Ruth E. Ley, Bruce W. Patterson, Elisa Fabbrini, Luigi Fontana, Bettina Mittendorfer, B. Selma Mohammed, Dennis T. Villareal and Shelby Sullivan and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Samuel Klein

373 papers receiving 47.0k citations

Hit Papers

Human gut microbes associ... 1997 2026 2006 2016 2006 1997 2009 2003 2007 2.0k 4.0k 6.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Human gut microbes associated with obesity
    2006 6.9k citations Samuel Klein et al. profile →
  2. Subcutaneous Adipose Tissue Releases Interleukin-6, But Not Tumor Necrosis Factor-α,in Vivo1
    1997 1.6k citations Samuel Klein et al. profile →
  3. Obesity and Nonalcoholic Fatty Liver Disease: Biochemical, Metabolic, and Clinical Implications
    2009 1.6k citations Elisa Fabbrini, Samuel Klein et al. profile →
  4. A Randomized Trial of a Low-Carbohydrate Diet for Obesity
    2003 1.2k citations B. Selma Mohammed, Samuel Klein et al. profile →
  5. Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans
    2007 1.1k citations J. Christopher Eagon, Samuel Klein et al. Diabetes profile →
  6. Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
    2009 762 citations Elisa Fabbrini, Faidon Magkos et al. Proceedings of the National Academy of Sciences profile →
  7. Assessing Adiposity
    2011 681 citations Samuel Klein et al. Circulation profile →
  8. Clinical Implications of Obesity With Specific Focus on Cardiovascular Disease
    2004 677 citations Samuel Klein, Robert H. Eckel et al. Circulation profile →
  9. Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans
    2004 670 citations Samuel Klein et al. Proceedings of the National Academy of Sciences profile →
  10. An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein
    1997 648 citations Samuel Klein et al. profile →
  11. Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society
    2005 636 citations Samuel Klein et al. American Journal of Clinical Nutrition profile →
  12. Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity
    2016 623 citations Faidon Magkos, Jun Yoshino et al. profile →
  13. Weight maintenance and additional weight loss with liraglutide after low-calorie-diet-induced weight loss: The SCALE Maintenance randomized study
    2013 610 citations Samuel Klein et al. profile →
  14. Absence of an Effect of Liposuction on Insulin Action and Risk Factors for Coronary Heart Disease
    2004 561 citations Samuel Klein, Bruce W. Patterson et al. profile →
  15. Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease
    2019 534 citations Gordon I. Smith, Mahalakshmi Shankaran et al. Journal of Clinical Investigation profile →
  16. Why does obesity cause diabetes?
    2022 508 citations Samuel Klein et al. profile →
  17. Energy balance and its components: implications for body weight regulation
    2012 480 citations Kevin D. Hall, Samuel Klein et al. American Journal of Clinical Nutrition profile →
  18. A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism
    2012 460 citations Nada A. Abumrad, Samuel Klein et al. profile →
  19. Metabolically healthy obesity: facts and fantasies
    2019 404 citations Gordon I. Smith, Bettina Mittendorfer et al. Journal of Clinical Investigation profile →
  20. Fish oil–derived n−3 PUFA therapy increases muscle mass and function in healthy older adults
    2015 369 citations Gordon I. Smith, Dominic N. Reeds et al. American Journal of Clinical Nutrition profile →
  21. Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes
    2021 277 citations Dmitri Samovski, Samuel Klein et al. profile →
  22. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
    2021 259 citations Jun Yoshino, Gary J. Patti et al. profile →
  23. Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH
    2021 245 citations Sabine Daemen, Mandy M. Chan et al. profile →
  24. The energy balance model of obesity: beyond calories in, calories out
    2022 179 citations Kevin D. Hall, I. Sadaf Farooqi et al. American Journal of Clinical Nutrition profile →
  25. Is Weight Loss–Induced Muscle Mass Loss Clinically Relevant?
    2024 96 citations Kevin D. Hall, Samuel Klein et al. profile →
  26. Cardiometabolic characteristics of people with metabolically healthy and unhealthy obesity
    2024 50 citations Max C. Petersen, Gordon I. Smith et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Samuel Klein 23.6k 12.7k 11.9k 10.3k 6.6k 383 48.5k
Peter Arner 21.2k 0.9× 13.1k 1.0× 10.8k 0.9× 8.6k 0.8× 5.4k 0.8× 576 43.9k
Takashi Kadowaki 16.3k 0.7× 17.1k 1.3× 25.1k 2.1× 14.1k 1.4× 10.4k 1.6× 869 62.0k
Éric Ravussin 32.6k 1.4× 9.5k 0.7× 8.4k 0.7× 6.9k 0.7× 3.6k 0.5× 559 54.2k
Richard N. Bergman 12.2k 0.5× 7.1k 0.6× 10.9k 0.9× 16.1k 1.6× 9.3k 1.4× 623 42.3k
Michael D. Jensen 19.3k 0.8× 7.1k 0.6× 5.1k 0.4× 8.1k 0.8× 10.5k 1.6× 324 37.7k
Matthias Blüher 17.8k 0.8× 14.7k 1.2× 12.7k 1.1× 5.6k 0.5× 4.4k 0.7× 698 41.3k
Bente Klarlund Pedersen 30.8k 1.3× 12.4k 1.0× 16.2k 1.4× 3.7k 0.4× 3.8k 0.6× 758 71.8k
Christos S. Mantzoros 21.3k 0.9× 20.1k 1.6× 10.1k 0.8× 9.7k 0.9× 4.1k 0.6× 642 56.4k
Steven E. Kahn 13.3k 0.6× 9.2k 0.7× 12.7k 1.1× 21.1k 2.1× 12.9k 2.0× 471 46.7k
Rudolph L. Leibel 17.5k 0.7× 13.2k 1.0× 9.4k 0.8× 4.2k 0.4× 3.9k 0.6× 270 37.9k

Countries citing papers authored by Samuel Klein

Since Specialization
Citations

This map shows the geographic impact of Samuel Klein's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Samuel Klein with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Samuel Klein more than expected).

Fields of papers citing papers by Samuel Klein

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Samuel Klein. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Samuel Klein. The network helps show where Samuel Klein may publish in the future.

Co-authorship network of co-authors of Samuel Klein

This figure shows the co-authorship network connecting the top 25 collaborators of Samuel Klein. A scholar is included among the top collaborators of Samuel Klein based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Samuel Klein. Samuel Klein is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Samovski, Dmitri, Gordon I. Smith, Hector H. Palacios, et al.. (2025). Effect of Marked Weight Loss on Adipose Tissue Biology in People With Obesity and Type 2 Diabetes. Diabetes Care. 48(8). 1342–1351. 3 indexed citations
2.
Saha, Pradip, Evelyn Groot, Lin Tan, et al.. (2025). N-acetylaspartate from fat cells regulates postprandial body temperature. Nature Metabolism. 7(8). 1524–1535.
3.
Singer, Jason, Daniel Ferguson, Trevor M. Shew, et al.. (2024). Adipocyte lipin 1 expression associates with human metabolic health and regulates systemic metabolism in mice. Journal of Clinical Investigation. 134(23).
4.
Mittendorfer, Bettina, Stephan van Vliet, Gordon I. Smith, et al.. (2024). Impaired plasma glucose clearance is a key determinant of fasting hyperglycemia in people with obesity. Obesity. 32(3). 540–546. 2 indexed citations
5.
Lobo, Julio, Caitlin Schneider, Samuel Klein, et al.. (2024). Methods and validation of velacur determined fat fraction in patients with MASLD. SHILAP Revista de lepidopterología. 2(2). 100061–100061. 1 indexed citations
6.
Handelsman, Yehuda, Javed Butler, George L. Bakris, et al.. (2023). Early intervention and intensive management of patients with diabetes, cardiorenal, and metabolic diseases. Journal of Diabetes and its Complications. 37(2). 108389–108389. 43 indexed citations
7.
Chan, Mandy M., Sabine Daemen, Joseph W. Beals, et al.. (2023). Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease. JHEP Reports. 5(11). 100877–100877. 14 indexed citations
8.
Mittendorfer, Bettina, Bruce W. Patterson, Debra Haire‐Joshu, et al.. (2023). Insulin Sensitivity and β-Cell Function During Early and Late Pregnancy in Women With and Without Gestational Diabetes Mellitus. Diabetes Care. 46(12). 2147–2154. 10 indexed citations
9.
Hall, Kevin D., I. Sadaf Farooqi, Samuel Klein, et al.. (2022). The energy balance model of obesity: beyond calories in, calories out. American Journal of Clinical Nutrition. 115(5). 1243–1254. 179 indexed citations breakdown →
10.
Koh, Han‐Chow E., Stephan van Vliet, Gretchen A. Meyer, et al.. (2021). Heterogeneity in insulin-stimulated glucose uptake among different muscle groups in healthy lean people and people with obesity. Diabetologia. 64(5). 1158–1168. 19 indexed citations
11.
Kanwal, Fasiha, Jay H. Shubrook, Zobair M. Younossi, et al.. (2021). Preparing for the NASH epidemic: A call to action. Obesity. 29(9). 1401–1412. 11 indexed citations
12.
Kanwal, Fasiha, Jay H. Shubrook, Zobair M. Younossi, et al.. (2021). Preparing for the NASH Epidemic: A Call to Action. Diabetes Care. 44(9). 2162–2172. 27 indexed citations
13.
Chondronikola, Maria, Faidon Magkos, Jun Yoshino, et al.. (2018). Effect of Progressive Weight Loss on Lactate Metabolism: A Randomized Controlled Trial. Obesity. 26(4). 683–688. 18 indexed citations
14.
Vliet, Stephan van, Gordon I. Smith, R. Ramaswamy, et al.. (2018). The muscle anabolic effect of protein ingestion during a hyperinsulinaemic euglycaemic clamp in middle‐aged women is not caused by leucine alone. The Journal of Physiology. 596(19). 4681–4692. 10 indexed citations
15.
Barritt, A. Sidney, Norman Gitlin, Samuel Klein, et al.. (2017). Design and rationale for a real-world observational cohort of patients with nonalcoholic fatty liver disease: The TARGET-NASH study. Contemporary Clinical Trials. 61. 33–38. 39 indexed citations
16.
Craft, Clarissa S., Terri Pietka, Timothy Schappe, et al.. (2014). The Extracellular Matrix Protein MAGP1 Supports Thermogenesis and Protects Against Obesity and Diabetes Through Regulation of TGF-β. Diabetes. 63(6). 1920–1932. 53 indexed citations
17.
Fabbrini, Elisa, Faidon Magkos, B. Selma Mohammed, et al.. (2009). Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity. Proceedings of the National Academy of Sciences. 106(36). 15430–15435. 762 indexed citations breakdown →
18.
Lin, Cheng‐Hung, Pilar Herrero, Alan D. Waggoner, et al.. (2009). Abstract 1563: Weight Loss Improves Right Atrial and Ventricular Function and Metabolism in Obese Humans. Circulation. 120.
19.
Klein, Samuel. (2005). Obezite Tedavisi İçin Para Ödemek Para Ediyor mu. Gastroenterology. 1(2). 82–82. 2 indexed citations
20.
Klein, Samuel, V. R. Young, George L. Blackburn, B R Bistrian, & Robert R. Wolfe. (1986). Palmitate and glycerol kinetics during brief starvation in normal weight young adult and elderly subjects.. Journal of Clinical Investigation. 78(4). 928–933. 115 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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