Irving L. Weissman

191.5k total citations · 66 hit papers
836 papers, 131.7k citations indexed

About

Irving L. Weissman is a scholar working on Immunology, Molecular Biology and Hematology. According to data from OpenAlex, Irving L. Weissman has authored 836 papers receiving a total of 131.7k indexed citations (citations by other indexed papers that have themselves been cited), including 386 papers in Immunology, 290 papers in Molecular Biology and 202 papers in Hematology. Recurrent topics in Irving L. Weissman's work include Immune Cell Function and Interaction (150 papers), Hematopoietic Stem Cell Transplantation (150 papers) and T-cell and B-cell Immunology (145 papers). Irving L. Weissman is often cited by papers focused on Immune Cell Function and Interaction (150 papers), Hematopoietic Stem Cell Transplantation (150 papers) and T-cell and B-cell Immunology (145 papers). Irving L. Weissman collaborates with scholars based in United States, India and Japan. Irving L. Weissman's co-authors include Sean J. Morrison, Michael F. Clarke, Tannishtha Reya, Amy J. Wagers, Koichi Akashi, Eugene C. Butcher, Ravindra Majeti, Derrick J. Rossi, Toshihiro Miyamoto and Julie L. Christensen and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Irving L. Weissman

820 papers receiving 128.4k citations

Hit Papers

Stem cells, cancer, and cancer stem cells 1980 2026 1995 2010 2001 1991 2006 1988 2000 2.5k 5.0k 7.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Stem cells, cancer, and cancer stem cells
    2001 7.5k citations Tannishtha Reya, Sean J. Morrison et al. Nature profile →
  2. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    1991 3.5k citations Irving L. Weissman et al. profile →
  3. Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells
    2006 2.4k citations Michael F. Clarke, Irving L. Weissman et al. Cancer Research profile →
  4. Purification and Characterization of Mouse Hematopoietic Stem Cells
    1988 2.2k citations Irving L. Weissman et al. Science profile →
  5. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    2000 1.9k citations Irving L. Weissman et al. Nature profile →
  6. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo
    2000 1.8k citations Irving L. Weissman et al. profile →
  7. Wnt proteins are lipid-modified and can act as stem cell growth factors
    2003 1.8k citations Irving L. Weissman, Tannishtha Reya et al. Nature profile →
  8. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
    2007 1.7k citations Irving L. Weissman, Michael F. Clarke et al. Proceedings of the National Academy of Sciences profile →
  9. Rejuvenation of aged progenitor cells by exposure to a young systemic environment
    2005 1.7k citations Amy J. Wagers, Irving L. Weissman et al. Nature profile →
  10. PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
    2017 1.6k citations Benson M. George, Jonathan M. Tsai et al. Nature profile →
  11. A role for Wnt signalling in self-renewal of haematopoietic stem cells
    2003 1.6k citations Tannishtha Reya, Irving L. Weissman et al. Nature profile →
  12. Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow
    1997 1.6k citations Irving L. Weissman et al. profile →
  13. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
    2003 1.5k citations Irving L. Weissman, Sean J. Morrison et al. Nature profile →
  14. Direct isolation of human central nervous system stem cells
    2000 1.4k citations Anna Masek, Irving L. Weissman et al. Proceedings of the National Academy of Sciences profile →
  15. CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells
    2009 1.3k citations Irving L. Weissman et al. profile →
  16. Stem Cells
    2000 1.3k citations Irving L. Weissman profile →
  17. New tools for studying microglia in the mouse and human CNS
    2016 1.3k citations Nathaniel B. Fernhoff, Irving L. Weissman et al. Proceedings of the National Academy of Sciences profile →
  18. Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium
    2004 1.3k citations Amy J. Wagers, Julie L. Christensen et al. Nature profile →
  19. A cell-surface molecule involved in organ-specific homing of lymphocytes
    1983 1.3k citations Irving L. Weissman et al. Nature profile →
  20. CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis
    2009 1.2k citations Irving L. Weissman et al. profile →
  21. α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1
    1993 1.2k citations Irving L. Weissman et al. profile →
  22. Little Evidence for Developmental Plasticity of Adult Hematopoietic Stem Cells
    2002 1.1k citations Amy J. Wagers, Richard I. Sherwood et al. Science profile →
  23. Granulocyte–Macrophage Progenitors as Candidate Leukemic Stem Cells in Blast-Crisis CML
    2004 1.1k citations Scott J. Dylla, Irving L. Weissman et al. profile →
  24. CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy
    2019 956 citations Irving L. Weissman et al. Nature profile →
  25. Plasticity of Adult Stem Cells
    2004 866 citations Amy J. Wagers, Irving L. Weissman profile →
  26. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    2007 852 citations Derrick J. Rossi, David Bryder et al. Nature profile →
  27. Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma
    2010 845 citations Irving L. Weissman et al. profile →
  28. A molecular cell atlas of the human lung from single-cell RNA sequencing
    2020 840 citations Rahul Sinha, Irving L. Weissman et al. Nature profile →
  29. Cell intrinsic alterations underlie hematopoietic stem cell aging
    2005 808 citations Derrick J. Rossi, David Bryder et al. Proceedings of the National Academy of Sciences profile →
  30. The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
    1994 803 citations Sean J. Morrison, Irving L. Weissman profile →
  31. Langerhans cells renew in the skin throughout life under steady-state conditions
    2002 732 citations Amy J. Wagers, Irving L. Weissman et al. profile →
  32. Biology of Hematopoietic Stem Cells and Progenitors: Implications for Clinical Application
    2003 724 citations Amy J. Wagers, Irving L. Weissman et al. profile →
  33. Physiological Migration of Hematopoietic Stem and Progenitor Cells
    2001 717 citations Amy J. Wagers, Irving L. Weissman et al. Science profile →
  34. Phagocytosis checkpoints as new targets for cancer immunotherapy
    2019 689 citations Irving L. Weissman et al. profile →
  35. Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche
    2009 684 citations Irving L. Weissman et al. profile →
  36. Stems Cells and the Pathways to Aging and Cancer
    2008 682 citations Derrick J. Rossi, Irving L. Weissman et al. profile →
  37. Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age
    2011 671 citations Derrick J. Rossi, Irving L. Weissman et al. Proceedings of the National Academy of Sciences profile →
  38. Stem and Progenitor Cells: Origins, Phenotypes, Lineage Commitments, and Transdifferentiations
    2001 664 citations Irving L. Weissman et al. profile →
  39. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
    1999 645 citations Sean J. Morrison, Irving L. Weissman et al. Proceedings of the National Academy of Sciences profile →
  40. The aging of hematopoietic stem cells
    1996 642 citations Sean J. Morrison, Irving L. Weissman et al. profile →
  41. Translating Stem and Progenitor Cell Biology to the Clinic: Barriers and Opportunities
    2000 621 citations Irving L. Weissman Science profile →
  42. The Biology of Hematopoietic Stem Cells
    1995 596 citations Sean J. Morrison, Irving L. Weissman et al. profile →
  43. Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47
    2010 594 citations Kipp Weiskopf, Stephen B. Willingham et al. profile →
  44. Hematopoietic stem cell: self‐renewal versus differentiation
    2010 585 citations Irving L. Weissman et al. profile →
  45. Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells
    2001 579 citations Julie L. Christensen, Irving L. Weissman Proceedings of the National Academy of Sciences profile →
  46. Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis.
    1991 547 citations Irving L. Weissman et al. The Journal of Experimental Medicine profile →
  47. Developing Lymph Nodes Collect CD4 + CD3 − LTβ + Cells That Can Differentiate to APC, NK Cells, and Follicular Cells but Not T or B Cells
    1997 546 citations Irving L. Weissman et al. profile →
  48. Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
    2010 541 citations Matt van de Rijn, Michael T. Longaker et al. Nature profile →
  49. Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies
    2013 537 citations Irving L. Weissman et al. profile →
  50. A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells
    1990 528 citations Irving L. Weissman et al. profile →
  51. Hematopoietic Stem Cells
    2006 522 citations David Bryder, Derrick J. Rossi et al. profile →
  52. Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia
    2012 522 citations Irving L. Weissman et al. profile →
  53. Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells
    2009 513 citations Matt van de Rijn, Irving L. Weissman et al. Proceedings of the National Academy of Sciences profile →
  54. The CD47–SIRPα pathway in cancer immune evasion and potential therapeutic implications
    2012 509 citations Irving L. Weissman et al. profile →
  55. Anti-CD47 antibody–mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response
    2013 506 citations Jens-Peter Volkmer, Stephen B. Willingham et al. Proceedings of the National Academy of Sciences profile →
  56. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
    2010 506 citations Deepta Bhattacharya, Irving L. Weissman et al. Proceedings of the National Academy of Sciences profile →
  57. CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis
    2016 500 citations Jens-Peter Volkmer, Kelly M. McKenna et al. Nature profile →
  58. Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
    2014 494 citations Irving L. Weissman et al. Proceedings of the National Academy of Sciences profile →
  59. Identification and isolation of a dermal lineage with intrinsic fibrogenic potential
    2015 492 citations Yuval Rinkevich, Graham G. Walmsley et al. Science profile →
  60. Thymus cell migration: Quantitative aspects of cellular traffic from the thymus to the periphery in mice
    1980 480 citations Irving L. Weissman et al. profile →
  61. The purification and characterization of fetal liver hematopoietic stem cells.
    1995 470 citations Sean J. Morrison, Irving L. Weissman et al. Proceedings of the National Academy of Sciences profile →
  62. Comprehensive methylome map of lineage commitment from haematopoietic progenitors
    2010 467 citations Derrick J. Rossi, Irving L. Weissman et al. Nature profile →
  63. Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy
    2017 428 citations Kipp Weiskopf, Kevin S. Kao et al. profile →
  64. Improving immune–vascular crosstalk for cancer immunotherapy
    2018 420 citations Irving L. Weissman et al. profile →
  65. Single-cell analysis reveals T cell infiltration in old neurogenic niches
    2019 363 citations Benson M. George, Irving L. Weissman et al. Nature profile →
  66. Depleting myeloid-biased haematopoietic stem cells rejuvenates aged immunity
    2024 96 citations Joseph J. Noh, Irving L. Weissman et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Irving L. Weissman United States 182 59.2k 47.2k 30.0k 24.6k 17.0k 836 131.7k
Zena Werb United States 151 45.6k 0.8× 18.5k 0.4× 35.3k 1.2× 7.9k 0.3× 5.0k 0.3× 416 110.4k
David Baltimore United States 190 76.2k 1.3× 46.6k 1.0× 18.2k 0.6× 10.0k 0.4× 6.9k 0.4× 804 141.8k
Peter Carmeliet Belgium 151 53.1k 0.9× 11.7k 0.2× 15.0k 0.5× 8.2k 0.3× 6.4k 0.4× 729 100.0k
Lewis C. Cantley United States 183 104.9k 1.8× 16.8k 0.4× 27.4k 0.9× 4.9k 0.2× 8.6k 0.5× 710 150.4k
Sean J. Morrison United States 92 32.4k 0.5× 10.1k 0.2× 21.7k 0.7× 12.8k 0.5× 9.4k 0.6× 183 62.4k
Tak W. Mak Canada 156 49.6k 0.8× 34.0k 0.7× 22.6k 0.8× 3.8k 0.2× 4.1k 0.2× 710 96.1k
Stuart H. Orkin United States 157 51.2k 0.9× 12.1k 0.3× 5.8k 0.2× 16.6k 0.7× 14.4k 0.8× 539 76.4k
Timothy A. Springer United States 153 26.0k 0.4× 43.4k 0.9× 11.4k 0.4× 14.1k 0.6× 2.4k 0.1× 536 91.5k
George D. Yancopoulos United States 161 55.1k 0.9× 16.0k 0.3× 14.3k 0.5× 3.1k 0.1× 4.4k 0.3× 430 103.1k
Judah Folkman United States 141 62.8k 1.1× 8.3k 0.2× 24.5k 0.8× 6.9k 0.3× 5.5k 0.3× 395 105.2k

Countries citing papers authored by Irving L. Weissman

Since Specialization
Citations

This map shows the geographic impact of Irving L. Weissman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Irving L. Weissman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Irving L. Weissman more than expected).

Fields of papers citing papers by Irving L. Weissman

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Irving L. Weissman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Irving L. Weissman. The network helps show where Irving L. Weissman may publish in the future.

Co-authorship network of co-authors of Irving L. Weissman

This figure shows the co-authorship network connecting the top 25 collaborators of Irving L. Weissman. A scholar is included among the top collaborators of Irving L. Weissman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Irving L. Weissman. Irving L. Weissman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Banuelos, Allison, Dongdong Feng, Kevin S. Kao, et al.. (2021). Combining CD47 blockade with trastuzumab eliminates HER2-positive breast cancer cells and overcomes trastuzumab tolerance. Proceedings of the National Academy of Sciences. 118(29). 95 indexed citations
2.
Cannon, Paula M., Aravind Asokan, Agnieszka Czechowicz, et al.. (2021). Safe and Effective In Vivo Targeting and Gene Editing in Hematopoietic Stem Cells: Strategies for Accelerating Development. Human Gene Therapy. 32(1-2). 31–42. 17 indexed citations
3.
Zalc, Antoine, Rahul Sinha, Gunsagar S. Gulati, et al.. (2021). Reactivation of the pluripotency program precedes formation of the cranial neural crest. Science. 371(6529). 89 indexed citations
4.
Ghosn, Eliver, Momoko Yoshimoto, Hiromitsu Nakauchi, Irving L. Weissman, & Leonore A. Herzenberg. (2019). Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes. Development. 146(15). 44 indexed citations
5.
Gulati, Gunsagar S., Joseph J. Noh, Daniel J. Wesche, et al.. (2019). Neogenin-1 distinguishes between myeloid-biased and balanced Hoxb5 + mouse long-term hematopoietic stem cells. Proceedings of the National Academy of Sciences. 116(50). 25115–25125. 30 indexed citations
6.
Kim, Young-Eun, Minji Lee, Seongju Jeong, et al.. (2018). HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice. Disease Models & Mechanisms. 11(7). 76 indexed citations
7.
Tsai, Jonathan M., Pang Wei Koh, Ania Stefańska, et al.. (2017). Localized hepatic lobular regeneration by central-vein–associated lineage-restricted progenitors. Proceedings of the National Academy of Sciences. 114(14). 3654–3659. 10 indexed citations
8.
Wernig, Gerlinde, Shih‐Yu Chen, Lu Cui, et al.. (2017). Unifying mechanism for different fibrotic diseases. Proceedings of the National Academy of Sciences. 114(18). 4757–4762. 145 indexed citations
9.
Corey, Daniel, Yuval Rinkevich, & Irving L. Weissman. (2016). Dynamic Patterns of Clonal Evolution in Tumor Vasculature Underlie Alterations in Lymphocyte–Endothelial Recognition to Foster Tumor Immune Escape. Cancer Research. 76(6). 1348–1353. 19 indexed citations
10.
Murakami, Jodi, Baohui Xu, Christopher B. Franco, et al.. (2015). Evidence that β7 Integrin Regulates Hematopoietic Stem Cell Homing and Engraftment Through Interaction with MAdCAM-1. Stem Cells and Development. 25(1). 18–26. 23 indexed citations
11.
Rinkevich, Yuval, Graham G. Walmsley, Michael S. Hu, et al.. (2015). Identification and isolation of a dermal lineage with intrinsic fibrogenic potential. Science. 348(6232). aaa2151–aaa2151. 492 indexed citations breakdown →
12.
Weiskopf, Kipp, Aaron M. Ring, Chia Chi M. Ho, et al.. (2013). Engineered SIRPα Variants as Immunotherapeutic Adjuvants to Anticancer Antibodies. Science. 341(6141). 88–91. 376 indexed citations
13.
Monje, Michelle, Siddhartha S. Mitra, Morgan E. Freret, et al.. (2011). Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma. Proceedings of the National Academy of Sciences. 108(11). 4453–4458. 215 indexed citations
14.
Rossi, Derrick J., Iiro Rajantie, Seppo Ylä‐Herttuala, et al.. (2008). Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth. Proceedings of the National Academy of Sciences. 105(18). 6620–6625. 294 indexed citations
15.
Serafini, Marta, Scott J. Dylla, Masayuki Oki, et al.. (2007). Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells. The Journal of Experimental Medicine. 204(1). 129–139. 75 indexed citations
16.
Luckey, Chance John, Deepta Bhattacharya, Ananda W. Goldrath, et al.. (2006). Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells. Proceedings of the National Academy of Sciences. 103(9). 3304–3309. 213 indexed citations
17.
Bhattacharya, Deepta, Derrick J. Rossi, David Bryder, & Irving L. Weissman. (2005). Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning. The Journal of Experimental Medicine. 203(1). 73–85. 96 indexed citations
18.
Kelly, Stephen, Tonya Bliss, Guohua Sun, et al.. (2004). Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. Proceedings of the National Academy of Sciences. 101(32). 11839–11844. 488 indexed citations
19.
Wagers, Amy J., Richard I. Sherwood, Julie L. Christensen, & Irving L. Weissman. (2002). Little Evidence for Developmental Plasticity of Adult Hematopoietic Stem Cells. Science. 297(5590). 2256–2259. 1116 indexed citations breakdown →
20.
Reya, Tannishtha, Sean J. Morrison, Michael F. Clarke, & Irving L. Weissman. (2001). Stem cells, cancer, and cancer stem cells. Nature. 414(6859). 105–111. 7501 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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