Michael F. Clarke

66.6k total citations · 19 hit papers
129 papers, 44.1k citations indexed

About

Michael F. Clarke is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Michael F. Clarke has authored 129 papers receiving a total of 44.1k indexed citations (citations by other indexed papers that have themselves been cited), including 82 papers in Molecular Biology, 60 papers in Oncology and 21 papers in Cancer Research. Recurrent topics in Michael F. Clarke's work include Cancer Cells and Metastasis (49 papers), Epigenetics and DNA Methylation (24 papers) and Cancer-related Molecular Pathways (16 papers). Michael F. Clarke is often cited by papers focused on Cancer Cells and Metastasis (49 papers), Epigenetics and DNA Methylation (24 papers) and Cancer-related Molecular Pathways (16 papers). Michael F. Clarke collaborates with scholars based in United States, India and China. Michael F. Clarke's co-authors include Sean J. Morrison, Irving L. Weissman, Max S. Wicha, Muhammad Al‐Hajj, Tannishtha Reya, Adalberto Benito‐Hernández, Piero Dalerba, Robert W. Cho, In-Kyung Park and Dalong Qian and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Michael F. Clarke

127 papers receiving 43.2k citations

Hit Papers

Prospective identification of tumorigenic breast cancer c... 2001 2026 2009 2017 2003 2001 2007 2006 2003 2.5k 5.0k 7.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Prospective identification of tumorigenic breast cancer cells
    2003 8.1k citations Muhammad Al‐Hajj, Max S. Wicha et al. Proceedings of the National Academy of Sciences profile →
  2. Stem cells, cancer, and cancer stem cells
    2001 7.5k citations Tannishtha Reya, Sean J. Morrison et al. Nature profile →
  3. Identification of Pancreatic Cancer Stem Cells
    2007 2.6k citations Piero Dalerba, Max S. Wicha et al. profile →
  4. Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells
    2006 2.4k citations Michael F. Clarke, Irving L. Weissman et al. profile →
  5. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    2003 1.9k citations Michael F. Clarke, Max S. Wicha et al. profile →
  6. Phenotypic characterization of human colorectal cancer stem cells
    2007 1.7k citations Piero Dalerba, Scott J. Dylla et al. Proceedings of the National Academy of Sciences profile →
  7. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
    2007 1.7k citations Piero Dalerba, Irving L. Weissman et al. Proceedings of the National Academy of Sciences profile →
  8. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
    2003 1.5k citations Dalong Qian, Mark J. Kiel et al. Nature profile →
  9. Applying the principles of stem-cell biology to cancer
    2003 1.2k citations Michael F. Clarke, Sean J. Morrison et al. profile →
  10. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    2003 1.0k citations Michael F. Clarke, Sean J. Morrison et al. Nature profile →
  11. Cancer Stem Cells: Models and Concepts
    2006 987 citations Piero Dalerba, Robert W. Cho et al. Annual Review of Medicine profile →
  12. Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells
    2009 971 citations Yohei Shimono, Maider Zabala et al. Cell profile →
  13. The Biology of Cancer Stem Cells
    2007 811 citations Neethan A. Lobo, Yohei Shimono et al. profile →
  14. The Prognostic Role of a Gene Signature from Tumorigenic Breast-Cancer Cells
    2007 742 citations Xinhao Wang, Piero Dalerba et al. profile →
  15. Single-cell transcriptional diversity is a hallmark of developmental potential
    2020 712 citations Gunsagar S. Gulati, Shaheen S. Sikandar et al. Science profile →
  16. Self-renewal and solid tumor stem cells
    2004 709 citations Muhammad Al‐Hajj, Michael F. Clarke profile →
  17. Stem Cells and Cancer: Two Faces of Eve
    2006 700 citations Michael F. Clarke, Margaret T. Fuller Cell profile →
  18. Quantitative assessment of single-cell RNA-sequencing methods
    2013 535 citations Tomer Kalisky, Piero Dalerba et al. Nature Methods profile →
  19. CDX2 as a Prognostic Biomarker in Stage II and Stage III Colon Cancer
    2016 330 citations Piero Dalerba, Debashis Sahoo et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Michael F. Clarke United States 60 27.0k 25.7k 12.1k 4.1k 3.7k 129 44.1k
Max S. Wicha United States 85 29.3k 1.1× 22.4k 0.9× 12.7k 1.1× 5.5k 1.3× 3.3k 0.9× 291 43.6k
Kornélia Polyák United States 85 26.6k 1.0× 30.3k 1.2× 14.8k 1.2× 4.1k 1.0× 5.0k 1.4× 202 49.8k
Robert S. Kerbel Canada 99 16.5k 0.6× 24.5k 1.0× 13.4k 1.1× 5.5k 1.3× 2.6k 0.7× 402 41.7k
Wafik S. El‐Deiry United States 100 23.2k 0.9× 32.9k 1.3× 9.3k 0.8× 5.3k 1.3× 3.5k 0.9× 584 46.9k
Amato J. Giaccia United States 103 10.8k 0.4× 23.1k 0.9× 17.4k 1.4× 4.6k 1.1× 4.3k 1.2× 350 40.3k
John E. Dick Canada 81 17.4k 0.6× 21.2k 0.8× 7.3k 0.6× 8.4k 2.0× 2.8k 0.8× 266 40.7k
Anirban Maitra United States 115 25.8k 1.0× 26.6k 1.0× 14.4k 1.2× 4.8k 1.2× 4.4k 1.2× 564 51.1k
Victor E. Velculescu United States 83 20.4k 0.8× 34.5k 1.3× 17.0k 1.4× 4.0k 1.0× 2.8k 0.8× 184 54.3k
Scott W. Lowe United States 123 23.0k 0.9× 50.1k 1.9× 16.9k 1.4× 8.5k 2.1× 5.1k 1.4× 325 69.6k
David A. Tuveson United States 83 21.2k 0.8× 19.6k 0.8× 9.4k 0.8× 7.5k 1.8× 2.5k 0.7× 200 41.1k

Countries citing papers authored by Michael F. Clarke

Since Specialization
Citations

This map shows the geographic impact of Michael F. Clarke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael F. Clarke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael F. Clarke more than expected).

Fields of papers citing papers by Michael F. Clarke

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael F. Clarke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael F. Clarke. The network helps show where Michael F. Clarke may publish in the future.

Co-authorship network of co-authors of Michael F. Clarke

This figure shows the co-authorship network connecting the top 25 collaborators of Michael F. Clarke. A scholar is included among the top collaborators of Michael F. Clarke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael F. Clarke. Michael F. Clarke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Kang, Minji, Gunsagar S. Gulati, José Juan Almagro Armenteros, et al.. (2025). Improved reconstruction of single-cell developmental potential with CytoTRACE 2. Nature Methods. 22(11). 2258–2263. 2 indexed citations
2.
Sikandar, Shaheen S., Gunsagar S. Gulati, Jane Antony, et al.. (2022). Identification of a minority population of LMO2 + breast cancer cells that integrate into the vasculature and initiate metastasis. Science Advances. 8(45). eabm3548–eabm3548. 3 indexed citations
3.
Reinitz, Felicia, Benedetta Nicolis di Robilant, Bayarsaikhan Chuluun, et al.. (2022). Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer’s model. eLife. 11. 9 indexed citations
4.
Gulati, Gunsagar S., Shaheen S. Sikandar, Daniel J. Wesche, et al.. (2020). Single-cell transcriptional diversity is a hallmark of developmental potential. Science. 367(6476). 405–411. 712 indexed citations breakdown →
5.
Zabala, Maider, Neethan A. Lobo, Jane Antony, et al.. (2020). LEFTY1 Is a Dual-SMAD Inhibitor that Promotes Mammary Progenitor Growth and Tumorigenesis. Cell stem cell. 27(2). 284–299.e8. 12 indexed citations
6.
Zarour, Luai, Sudarshan Anand, Kevin G. Billingsley, et al.. (2017). Colorectal Cancer Liver Metastasis: Evolving Paradigms and Future Directions. Cellular and Molecular Gastroenterology and Hepatology. 3(2). 163–173. 198 indexed citations
7.
Betancur, Paola, Brian J. Abraham, Ying Ying Yiu, et al.. (2017). A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer. Nature. 1 indexed citations
8.
Isobe, Taichi, Shigeo Hisamori, Daniel J. Hogan, et al.. (2014). miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway. eLife. 3. 155 indexed citations
9.
Kalisky, Tomer, Pradeep S. Rajendran, Debashis Sahoo, et al.. (2013). Analysis of Human Colon Tissue Cell Composition Using Single-Cell Gene-Expression PCR. Journal of Biomolecular Techniques JBT. 24. 2 indexed citations
10.
Diehn, Maximilian, Robert W. Cho, & Michael F. Clarke. (2009). Therapeutic Implications of the Cancer Stem Cell Hypothesis. Seminars in Radiation Oncology. 19(2). 78–86. 108 indexed citations
11.
Hoey, Timothy, Wan-Ching Yen, Fumiko Axelrod, et al.. (2009). DLL4 Blockade Inhibits Tumor Growth and Reduces Tumor-Initiating Cell Frequency. Cell stem cell. 5(2). 168–177. 318 indexed citations
12.
Cho, Robert W. & Michael F. Clarke. (2008). Recent advances in cancer stem cells. Current Opinion in Genetics & Development. 18(1). 48–53. 178 indexed citations
13.
Dylla, Scott J., Lucia Beviglia, Inkyung Park, et al.. (2008). Correction: Colorectal Cancer Stem Cells Are Enriched in Xenogeneic Tumors Following Chemotherapy. PLoS ONE. 3(8). 39 indexed citations
14.
Dalerba, Piero, Robert W. Cho, & Michael F. Clarke. (2006). Cancer Stem Cells: Models and Concepts. Annual Review of Medicine. 58(1). 267–284. 987 indexed citations breakdown →
15.
Clarke, Michael F. & Margaret T. Fuller. (2006). Stem Cells and Cancer: Two Faces of Eve. Cell. 124(6). 1111–1115. 700 indexed citations breakdown →
16.
Park, Inkyung, Sean J. Morrison, & Michael F. Clarke. (2004). Bmi1, stem cells, and senescence regulation. Journal of Clinical Investigation. 113(2). 175–179. 350 indexed citations
17.
Al‐Hajj, Muhammad, Max S. Wicha, Adalberto Benito‐Hernández, Sean J. Morrison, & Michael F. Clarke. (2003). Prospective identification of tumorigenic breast cancer cells. Proceedings of the National Academy of Sciences. 100(7). 3983–3988. 8099 indexed citations breakdown →
18.
Morrison, Sean J., Dalong Qian, Libuse Jerabek, et al.. (2002). A Genetic Determinant That Specifically Regulates the Frequency of Hematopoietic Stem Cells. The Journal of Immunology. 168(2). 635–642. 80 indexed citations
19.
Reya, Tannishtha, Sean J. Morrison, Michael F. Clarke, & Irving L. Weissman. (2001). Stem cells, cancer, and cancer stem cells. Nature. 414(6859). 105–111. 7501 indexed citations breakdown →
20.
Clarke, Michael F., et al.. (1988). Constitutive Expression of a c- myb cDNA Blocks Friend Murine Erythroleukemia Cell Differentiation. Molecular and Cellular Biology. 8(2). 884–892. 61 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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