Alexandra Grassian

3.4k total citations · 1 hit paper
17 papers, 1.7k citations indexed

About

Alexandra Grassian is a scholar working on Molecular Biology, Cancer Research and Genetics. According to data from OpenAlex, Alexandra Grassian has authored 17 papers receiving a total of 1.7k indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Molecular Biology, 9 papers in Cancer Research and 3 papers in Genetics. Recurrent topics in Alexandra Grassian's work include Cancer, Hypoxia, and Metabolism (6 papers), Mitochondrial Function and Pathology (3 papers) and Chromatin Remodeling and Cancer (3 papers). Alexandra Grassian is often cited by papers focused on Cancer, Hypoxia, and Metabolism (6 papers), Mitochondrial Function and Pathology (3 papers) and Chromatin Remodeling and Cancer (3 papers). Alexandra Grassian collaborates with scholars based in United States, Switzerland and Israel. Alexandra Grassian's co-authors include Joan S. Brugge, Zachary T. Schafer, Hanna Y. Irie, Zhenyang Jiang, Sizhen Gao, Loling Song, Pere Puigserver, Zachary Gerhart‐Hines, Christian M. Metallo and Raymond Pagliarini and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Journal of Clinical Oncology.

In The Last Decade

Alexandra Grassian

17 papers receiving 1.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

2009 808 citations Zachary T. Schafer, Alexandra Grassian et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alexandra Grassian United States	12	1.2k	797	367	166	125	17	1.7k
Ciro Zanca United States	18	1.3k 1.0×	793 1.0×	296 0.8×	158 1.0×	107 0.9×	25	1.8k
Lynn Kirkpatrick United States	15	991 0.8×	679 0.9×	295 0.8×	111 0.7×	179 1.4×	23	1.6k
Anna L. Stratford Canada	24	1.2k 1.0×	445 0.6×	567 1.5×	96 0.6×	130 1.0×	27	1.9k
Esther Bridges United Kingdom	21	1.1k 0.9×	744 0.9×	430 1.2×	72 0.4×	130 1.0×	38	1.7k
Oona Delpuech United Kingdom	20	1.1k 0.8×	460 0.6×	433 1.2×	92 0.6×	243 1.9×	33	1.7k
Anica Dricu Romania	26	811 0.7×	423 0.5×	374 1.0×	317 1.9×	158 1.3×	78	1.6k
Chang Hun Rhee South Korea	22	968 0.8×	405 0.5×	287 0.8×	268 1.6×	196 1.6×	34	1.8k
Georgios Kallifatidis United States	18	940 0.8×	364 0.5×	646 1.8×	213 1.3×	124 1.0×	26	1.7k
Estefanía Carrasco‐García Spain	25	817 0.7×	412 0.5×	387 1.1×	223 1.3×	116 0.9×	37	1.4k
Michael Milyavsky Israel	23	1.5k 1.2×	456 0.6×	725 2.0×	126 0.8×	148 1.2×	47	2.1k

Countries citing papers authored by Alexandra Grassian

Since Specialization

Citations

This map shows the geographic impact of Alexandra Grassian's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alexandra Grassian with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alexandra Grassian more than expected).

Fields of papers citing papers by Alexandra Grassian

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alexandra Grassian. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alexandra Grassian. The network helps show where Alexandra Grassian may publish in the future.

Co-authorship network of co-authors of Alexandra Grassian

This figure shows the co-authorship network connecting the top 25 collaborators of Alexandra Grassian. A scholar is included among the top collaborators of Alexandra Grassian based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alexandra Grassian. Alexandra Grassian is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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17 of 17 papers shown

Grassian, Alexandra, Andrew M. Haidle, James Α. Baker, et al.. (2024). BLU-808, a Potent and Selective Small Molecule Inhibitor of Wild-type c-KIT for Mast Cell Disorders. Journal of Allergy and Clinical Immunology. 153(2). AB62–AB62. 4 indexed citations

House, Nealia C., et al.. (2023). CDK2 regulates collapsed replication fork repair in CCNE1-amplified ovarian cancer cells via homologous recombination. NAR Cancer. 5(3). zcad039–zcad039. 15 indexed citations

Serrano, César, Sebastian Bauer, Yoon‐Koo Kang, et al.. (2022). Circulating tumor DNA (ctDNA) analyses of the phase III VOYAGER trial: KIT mutational landscape and outcomes in patients with advanced gastrointestinal stromal tumor (GIST).. Journal of Clinical Oncology. 40(16_suppl). 101–101. 4 indexed citations

Chan-Penebre, Elayne, Kelli Armstrong, Allison E. Drew, et al.. (2017). Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models. Molecular Cancer Therapeutics. 16(5). 850–860. 127 indexed citations

Kawano, Satoshi, Alexandra Grassian, Masumi Tsuda, et al.. (2016). Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma. PLoS ONE. 11(7). e0158888–e0158888. 58 indexed citations

Grassian, Alexandra, Sarah K. Knutson, Kevin W. Kuntz, et al.. (2015). A Medium-Throughput Single Cell CRISPR-Cas9 Assay to Assess Gene Essentiality. Biological Procedures Online. 17(1). 15–15. 5 indexed citations

Grassian, Alexandra, Seth J. Parker, Shawn M. Davidson, et al.. (2014). IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism. Cancer Research. 74(12). 3317–3331. 211 indexed citations

Grassian, Alexandra, Seth J. Parker, Ajit S. Divakaruni, et al.. (2014). IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism. DSpace@MIT (Massachusetts Institute of Technology). 83 indexed citations

Grassian, Alexandra, Raymond Pagliarini, & Derek Y. Chiang. (2014). Mutations of isocitrate dehydrogenase 1 and 2 in intrahepatic cholangiocarcinoma. Current Opinion in Gastroenterology. 30(3). 295–302. 42 indexed citations

10.

Grassian, Alexandra, Seth J. Parker, Shawn M. Davidson, et al.. (2014). Abstract LB-139: IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism. Cancer Research. 74(19_Supplement). LB–139. 2 indexed citations

11.

Grassian, Alexandra, Fallon Lin, Rosemary Barrett, et al.. (2012). Isocitrate Dehydrogenase (IDH) Mutations Promote a Reversible ZEB1/MicroRNA (miR)-200-dependent Epithelial-Mesenchymal Transition (EMT). Journal of Biological Chemistry. 287(50). 42180–42194. 83 indexed citations

12.

Locasale, Jason W., Alexandra Grassian, Rameen Beroukhim, et al.. (2012). Amplification of phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. BMC Proceedings. 6(S3). 2 indexed citations

13.

Grassian, Alexandra, Christian M. Metallo, Jonathan L. Coloff, Gregory Stephanopoulos, & Joan S. Brugge. (2011). Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation. Genes & Development. 25(16). 1716–1733. 146 indexed citations

14.

Grassian, Alexandra, Zachary T. Schafer, & Joan S. Brugge. (2010). ErbB2 Stabilizes Epidermal Growth Factor Receptor (EGFR) Expression via Erk and Sprouty2 in Extracellular Matrix-detached Cells. Journal of Biological Chemistry. 286(1). 79–90. 38 indexed citations

15.

Jagani, Zainab, Keli Song, Jeffery L. Kutok, et al.. (2009). Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL–Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors. Cancer Research. 69(16). 6546–6555. 40 indexed citations

16.

Schafer, Zachary T., Alexandra Grassian, Loling Song, et al.. (2009). Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment. Nature. 461(7260). 109–113. 808 indexed citations breakdown →

17.

Song, Keli, et al.. (2007). Apoptotic Pathways in Tumor Progression and Therapy. Advances in experimental medicine and biology. 615. 47–79. 80 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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