Seth J. Parker

7.7k total citations · 5 hit papers
37 papers, 5.3k citations indexed

About

Seth J. Parker is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Seth J. Parker has authored 37 papers receiving a total of 5.3k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Molecular Biology, 27 papers in Cancer Research and 10 papers in Oncology. Recurrent topics in Seth J. Parker's work include Cancer, Hypoxia, and Metabolism (26 papers), Mitochondrial Function and Pathology (12 papers) and Epigenetics and DNA Methylation (5 papers). Seth J. Parker is often cited by papers focused on Cancer, Hypoxia, and Metabolism (26 papers), Mitochondrial Function and Pathology (12 papers) and Epigenetics and DNA Methylation (5 papers). Seth J. Parker collaborates with scholars based in United States, Canada and United Kingdom. Seth J. Parker's co-authors include Christian M. Metallo, Matthew G. Vander Heiden, Dafna Bar‐Sagi, Shawn M. Davidson, Alec C. Kimmelman, Joshua D. Rabinowitz, Craig B. Thompson, Sean R. Hackett, Elda Grabocka and Michel Nofal and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Seth J. Parker

36 papers receiving 5.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

2013 1.3k citations Shawn M. Davidson, Seth J. Parker et al. Nature profile →
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

2020 844 citations Keisuke Yamamoto, Douglas E. Biancur et al. Nature profile →
Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

2014 438 citations Caroline A. Lewis, Seth J. Parker et al. Molecular Cell profile →
Reductive carboxylation supports redox homeostasis during anchorage-independent growth

2016 432 citations Lei Jiang, Alexander A. Shestov et al. Nature profile →
Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

2016 390 citations Robert Svensson, Seth J. Parker et al. profile →

Peers

Seth J. Parker

MB

CR

ONCOL

IMMUN

EPIDE

Yanhua Zheng United States

Brian J. Altman United States

Natalya N. Pavlova United States

Peggy P. Hsu United States

John D. Gordan United States

Ya’an Kang United States

Celia R. Berkers Netherlands

Jurre J. Kamphorst United States

Sophie Vasseur France

Juan Liu China

Yanhua Zheng United States

Seth J. Parker

3.8k ×1.1

MB

2.2k ×1.0

CR

782 ×0.7

ONCOL

585 ×0.9

IMMUN

479 ×0.7

EPIDE

Citations per year, relative to Seth J. Parker Seth J. Parker (= 1×) peers Yanhua Zheng

Countries citing papers authored by Seth J. Parker

Since Specialization

Citations

This map shows the geographic impact of Seth J. Parker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Seth J. Parker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Seth J. Parker more than expected).

Fields of papers citing papers by Seth J. Parker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Seth J. Parker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Seth J. Parker. The network helps show where Seth J. Parker may publish in the future.

Co-authorship network of co-authors of Seth J. Parker

This figure shows the co-authorship network connecting the top 25 collaborators of Seth J. Parker. A scholar is included among the top collaborators of Seth J. Parker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Seth J. Parker. Seth J. Parker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

1.

Karasinska, Joanna M., James T. Topham, Steve E. Kalloger, et al.. (2024). Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profiles. SHILAP Revista de lepidopterología. 12(1). 28–28. 5 indexed citations

2.

Thomson, Sarah B., et al.. (2024). Restricting lysine normalizes toxic catabolites associated with ALDH7A1 deficiency in cells and mice. Cell Reports. 43(12). 115069–115069. 6 indexed citations

3.

Zhao, Zhiyu, et al.. (2023). A Peptidisc-Based Survey of the Plasma Membrane Proteome of a Mammalian Cell. Molecular & Cellular Proteomics. 22(8). 100588–100588. 9 indexed citations

4.

Encarnación-Rosado, Joel, Albert S.W. Sohn, Douglas E. Biancur, et al.. (2023). Targeting pancreatic cancer metabolic dependencies through glutamine antagonism. Nature Cancer. 5(1). 85–99. 65 indexed citations

5.

Martino, Cameron, Lívia S. Zaramela, Bei Gao, et al.. (2022). Acetate reprograms gut microbiota during alcohol consumption. Nature Communications. 13(1). 4630–4630. 64 indexed citations

6.

Zhang, Haifeng, Ramon I. Klein Geltink, Seth J. Parker, & Poul H. Sorensen. (2022). Transsulfuration, minor player or crucial for cysteine homeostasis in cancer. Trends in Cell Biology. 32(9). 800–814. 87 indexed citations

7.

Mukhopadhyay, Subhadip, Douglas E. Biancur, Seth J. Parker, et al.. (2021). Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11. Proceedings of the National Academy of Sciences. 118(6). 58 indexed citations

8.

Parker, Seth J., Caroline R. Amendola, Kate E.R. Hollinshead, et al.. (2020). Selective Alanine Transporter Utilization Creates a Targetable Metabolic Niche in Pancreatic Cancer. Cancer Discovery. 10(7). 1018–1037. 116 indexed citations

9.

Amendola, Caroline R., Seth J. Parker, Ian M. Ahearn, et al.. (2019). KRAS4A directly regulates hexokinase 1. Nature. 576(7787). 482–486. 150 indexed citations

10.

Badur, Mehmet G., Seth J. Parker, Shenghong Ma, et al.. (2018). Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Cells. Cell Reports. 25(4). 1018–1026.e4. 65 indexed citations

11.

Zarei, Mahsa, Shruti Lal, Seth J. Parker, et al.. (2017). Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells. Cancer Research. 77(16). 4460–4471. 84 indexed citations

12.

Jiang, Lei, Alexander A. Shestov, Pamela Swain, et al.. (2016). Reductive carboxylation supports redox homeostasis during anchorage-independent growth. Nature. 532(7598). 255–258. 432 indexed citations breakdown →

13.

Parker, Seth J., Robert Svensson, Ajit S. Divakaruni, et al.. (2016). LKB1 promotes metabolic flexibility in response to energy stress. Metabolic Engineering. 43(Pt B). 208–217. 40 indexed citations

14.

Zhang, Hui, Mehmet G. Badur, Ajit S. Divakaruni, et al.. (2016). Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions. Cell Reports. 16(6). 1536–1547. 96 indexed citations

15.

Parker, Seth J. & Christian M. Metallo. (2015). Metabolic consequences of oncogenic IDH mutations. Pharmacology & Therapeutics. 152. 54–62. 115 indexed citations

16.

Grassian, Alexandra, Seth J. Parker, Shawn M. Davidson, et al.. (2014). IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism. Cancer Research. 74(12). 3317–3331. 211 indexed citations

17.

Grassian, Alexandra, Seth J. Parker, Ajit S. Divakaruni, et al.. (2014). IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism. DSpace@MIT (Massachusetts Institute of Technology). 83 indexed citations

18.

Lewis, Caroline A., Seth J. Parker, Brian P. Fiske, et al.. (2014). Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells. Molecular Cell. 55(2). 253–263. 438 indexed citations breakdown →

19.

Vacanti, Nathaniel M., Ajit S. Divakaruni, Courtney R. Green, et al.. (2014). Regulation of Substrate Utilization by the Mitochondrial Pyruvate Carrier. Molecular Cell. 56(5). 717–717. 4 indexed citations

20.

Vacanti, Nathaniel M., Ajit S. Divakaruni, Courtney R. Green, et al.. (2014). Regulation of Substrate Utilization by the Mitochondrial Pyruvate Carrier. Molecular Cell. 56(3). 425–435. 223 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact