Emanuele Perola
About
Emanuele Perola is a scholar working on Molecular Biology, Organic Chemistry and Computational Theory and Mathematics.
According to data from OpenAlex, Emanuele Perola has authored 33 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Molecular Biology, 11 papers in Organic Chemistry and 9 papers in Computational Theory and Mathematics. Recurrent topics in Emanuele Perola's work include Computational Drug Discovery Methods (9 papers), Cholinesterase and Neurodegenerative Diseases (6 papers) and Protein Structure and Dynamics (5 papers). Emanuele Perola is often cited by papers focused on Computational Drug Discovery Methods (9 papers), Cholinesterase and Neurodegenerative Diseases (6 papers) and Protein Structure and Dynamics (5 papers). Emanuele Perola collaborates with scholars based in United States, Italy and Germany. Emanuele Perola's co-authors include Paul S. Charifson, W. Patrick Walters, Doriano Lamba, Yuan‐Ping Pang, Luciano Cellai, Cecilia Bartolucci, Kun Xu, Franklyn G. Prendergast, Tiansheng Wang and Mario Brufani and has published in prestigious journals such as Angewandte Chemie International Edition, The EMBO Journal and Biochemistry.
In The Last Decade
Emanuele Perola
33 papers receiving 2.1k citations
Peers
Emanuele Perola
David Lagorce France
Georgina A. Holloway Australia
Abhinav Grover India
Amy C. Anderson United States
Peter Schmidtke Spain
Erin S. D. Bolstad United States
Jung‐Hsin Lin Taiwan
Olivier Spérandio France
Martha S. Head United States
Francesca Spyrakis Italy
Citations per year, relative to Emanuele Perola Emanuele Perola (= 1×)
peers
David Lagorce
Countries citing papers authored by Emanuele Perola
Since
Specialization
Citations
This map shows the geographic impact of Emanuele Perola's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Emanuele Perola with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Emanuele Perola more than expected).
Fields of papers citing papers by Emanuele Perola
Since
Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences
This network shows the impact of papers produced by Emanuele Perola. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Emanuele Perola. The network helps show where Emanuele Perola may publish in the future.
Co-authorship network of co-authors of Emanuele Perola
This figure shows the co-authorship network connecting the top 25 collaborators of Emanuele Perola. A scholar is included among the top collaborators of Emanuele Perola based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Emanuele Perola. Emanuele Perola is excluded from the visualization to improve readability, since they are connected to all nodes in the network.
All Works
1.
Grassian, Alexandra, Andrew M. Haidle, James Α. Baker, et al.. (2024). BLU-808, a Potent and Selective Small Molecule Inhibitor of Wild-type c-KIT for Mast Cell Disorders. Journal of Allergy and Clinical Immunology. 153(2). AB62–AB62.
2.
Clark, Michael P., Tiansheng Wang, Emanuele Perola, et al.. (2017). 2-N-Arylthiazole inhibitors of Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry Letters. 27(17). 3987–3991.
3.
VanderVen, Brian C., Wonsik Lee, Yan‐Cheng Liu, et al.. (2015). Novel Inhibitors of Cholesterol Degradation in Mycobacterium tuberculosis Reveal How the Bacterium’s Metabolism Is Constrained by the Intracellular Environment. PLoS Pathogens. 11(2). e1004679–e1004679.
4.
Boyd, Michael J., Upul K. Bandarage, Wenxin Gu, et al.. (2015). Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 25(9). 1990–1994.
5.
Byrn, Randal A., Steven J.M. Jones, Michael P. Clark, et al.. (2014). Preclinical Activity of VX-787, a First-in-Class, Orally Bioavailable Inhibitor of the Influenza Virus Polymerase PB2 Subunit. Antimicrobial Agents and Chemotherapy. 59(3). 1569–1582.
6.
Perola, Emanuele, Dean Stamos, Anne‐Laure Grillot, et al.. (2014). Successful application of serum shift prediction models to the design of dual targeting inhibitors of bacterial gyrase B and topoisomerase IV with improved in vivo efficacy. Bioorganic & Medicinal Chemistry Letters. 24(9). 2177–2181.
7.
Gu, Wenxin, Tiansheng Wang, François Maltais, et al.. (2012). Design, synthesis and biological evaluation of potent NAD+-dependent DNA ligase inhibitors as potential antibacterial agents. Part I: Aminoalkoxypyrimidine carboxamides. Bioorganic & Medicinal Chemistry Letters. 22(11). 3693–3698.
8.
Wang, Tiansheng, Wenxin Gu, Hardwin O’Dowd, et al.. (2012). Design, synthesis and biological evaluation of potent NAD+-dependent DNA ligase inhibitors as potential antibacterial agents. Part 2: 4-Amino-pyrido[2,3-d]pyrimidin-5(8H)-ones. Bioorganic & Medicinal Chemistry Letters. 22(11). 3699–3703.
9.
Perola, Emanuele. (2010). An Analysis of the Binding Efficiencies of Drugs and Their Leads in Successful Drug Discovery Programs. Journal of Medicinal Chemistry. 53(7). 2986–2997.
10.
Rao, B. Govinda, Upul K. Bandarage, Tiansheng Wang, et al.. (2007). Novel thiol-based TACE inhibitors: Rational design, synthesis, and SAR of thiol-containing aryl sulfonamides. Bioorganic & Medicinal Chemistry Letters. 17(8). 2250–2253.
11.
Perola, Emanuele, W. Patrick Walters, & Paul S. Charifson. (2004). A detailed comparison of current docking and scoring methods on systems of pharmaceutical relevance. Proteins Structure Function and Bioinformatics. 56(2). 235–249.
12.
Pang, Yuan‐Ping, Emanuele Perola, Kun Xu, & Franklyn G. Prendergast. (2001). EUDOC: a computer program for identification of drug interaction sites in macromolecules and drug leads from chemical databases. Journal of Computational Chemistry. 22(15). 1750–1771.
13.
Pang, Yuan‐Ping, Kun Xu, Thomas M. Kollmeyer, et al.. (2001). Discovery of a new inhibitor lead of adenovirus proteinase: steps toward selective, irreversible inhibitors of cysteine proteinases. FEBS Letters. 502(3). 93–97.
14.
Bartolucci, Cecilia, Emanuele Perola, Christian Pilger, Gregor Fels, & Doriano Lamba. (2000). Three-dimensional structure of a complex of galanthamine (Nivalin�) with acetylcholinesterase fromTorpedo californica: Implications for the design of new anti-Alzheimer drugs. Proteins Structure Function and Bioinformatics. 42(2). 182–191.
15.
Szyperski, Thomas, Matthias Götte, Martin Billeter, et al.. (1999). NMR structure of the chimeric hybrid duplex r(gcaguggc)⋅r(gcca)d(CTGC) comprising the tRNA-DNA junction formed during initiation of HIV-1 reverse transcription. Journal of Biomolecular NMR. 13(4). 343–355.
16.
Di, Antonino, Emanuele Perola, Barbara Bartolini, et al.. (1999). Fractions of Chemically Oversulphated Galactosaminoglycan Sulphates Inhibit Three Enveloped Viruses: Human Immunodeficiency Virus Type 1, Herpes Simplex Virus Type 1 and Human Cytomegalovirus. Antiviral chemistry & chemotherapy. 10(1). 33–38.
17.
Perola, Emanuele, Luciano Cellai, & Mario Brufani. (1998). Synthesis and activity studies of N-[ω-N′-(adamant-1′-yl)aminoalkyl]-2-(4′-dimethylaminophenyl)acetamides: In the search of selective inhibitors for the different molecular forms of acetylcholinesterase. Bioorganic & Medicinal Chemistry Letters. 8(6). 575–580.
18.
Perola, Emanuele, et al.. (1997). Long chain analogs of physostigmine as potential drugs for Alzheimer's disease: new insights into the mechanism of action in the inhibition of acetylcholinesterase. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1343(1). 41–50.
19.
Bartolucci, Cecilia, Luciano Cellai, Maria Adelaide Iannelli, et al.. (1995). Inhibition of human leukocyte elastase by chemically and naturally oversulfated galactosaminoglycans. Carbohydrate Research. 276(2). 401–408.
20.
Götte, Matthias, Thomas Hermann, Emanuele Perola, et al.. (1995). HIV-1 reverse transcriptase-associated RNase H cleaves RNA/RNA in arrested complexes: implications for the mechanism by which RNase H discriminates between RNA/RNA and RNA/DNA.. The EMBO Journal. 14(4). 833–841.
Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.
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