Loretta Dorstyn

4.5k citations

46 papers · 3.5k indexed · 1 hit paper · h-index 28

Impact in

Aging top 5%
Molecular Biology top 5%
- Cell death mechanisms and regulation
- Mitochondrial Function and Pathology
- Ubiquitin and proteasome pathways
- Insect Resistance and Genetics
- Inflammasome and immune disorders

Papers in ⓘ

Aging 1
Molecular Biology 38
- Cell death mechanisms and regulation 33
- Mitochondrial Function and Pathology 5

Co-authors: Sharad Kumar (44 shared papers)Sonia Shalini (9 shared papers)Swati Dawar (3 shared papers)Helena E. Richardson (6 shared papers)Leonie M. Quinn (5 shared papers)Stuart H. Read (5 shared papers)Joseph Puccini (9 shared papers)Christopher W. Akey (2 shared papers)
Journals: Cell Death and Differentiation (14 papers)Cell Death and Disease (6 papers)Journal of Biological Chemistry (5 papers)Proceedings of the National Academy of Sciences (4 papers)Oncogene (3 papers)
Partner nations: Australia United States United Kingdom

In The Last Decade

Loretta Dorstyn

46 papers receiving 3.5k citations

Hit Papers

align trajectories log scale

Old, new and emerging functions of caspases 2014 · 978 citations

Peers

Countries citing papers authored by Loretta Dorstyn

Since Specialization

Citations

This map shows the geographic impact of Loretta Dorstyn's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Loretta Dorstyn with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Loretta Dorstyn more than expected).

Fields of papers citing papers by Loretta Dorstyn

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Loretta Dorstyn. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Loretta Dorstyn. The network helps show where Loretta Dorstyn may publish in the future.

Co-authors

The 25 scholars most cited alongside Loretta Dorstyn, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Loretta Dorstyn Line = papers co-authored together Loretta Dorstyn links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 46 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Old, new and emerging functions of caspases Cell Death and Differentiation ·Sonia Shalini, Loretta Dorstyn, Swati Dawar, Sharad Kumar Hit paper breakdown →	2014	978
2	DRONC, an ecdysone-inducible Drosophila caspase Proceedings of the National Academy of Sciences ·Loretta Dorstyn, Paul A. Colussi, Leonie M. Quinn, Helena E. Richardson, Sharad Kumar	1999	238
3	New insights into apoptosome structure and function Cell Death and Differentiation ·Loretta Dorstyn, Christopher W. Akey, Sharad Kumar	2018	167
4	The role of cytochrome c in caspase activation in Drosophila melanogaster cells The Journal of Cell Biology ·Loretta Dorstyn, Stuart H. Read, Dimitrios Cakouros, Jun R. Huh, Bruce A. Hay, Sharad Kumar	2002	161
5	A tumor suppressor function for caspase-2 Proceedings of the National Academy of Sciences ·Lien H. Ho, Robyn Taylor, Loretta Dorstyn, Dimitrios Cakouros, Philippe Bouillet, Sharad Kumar	2009	135
6	An Essential Role for the Caspase Dronc in Developmentally Programmed Cell Death in Drosophila Journal of Biological Chemistry ·Leonie M. Quinn, Loretta Dorstyn, Kathryn Mills, Paul A. Colussi, Po Chen, Michelle Coombe, John Abrams, Sharad Kumar, Helena E. Richardson	2000	130
7	Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2 Blood ·Natalie J. Foot, Hazel Dalton, Linda Shearwin‐Whyatt, Loretta Dorstyn, Seong‐Seng Tan, Baoli Yang, Sharad Kumar	2008	115
8	DECAY, a Novel Drosophila Caspase Related to Mammalian Caspase-3 and Caspase-7 Journal of Biological Chemistry ·Loretta Dorstyn, Stuart H. Read, Leonie M. Quinn, Helena E. Richardson, Sharad Kumar	1999	109
9	Caspase-2 is required for cell death induced by cytoskeletal disruption Oncogene ·Lien H. Ho, Stuart H. Read, Loretta Dorstyn, Lidia Lambrusco, Sharad Kumar	2008	108
10	The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells The Journal of Cell Biology ·Loretta Dorstyn, Kathryn Mills, Yuri Lazebnik, Sharad Kumar	2004	100
11	Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons Proceedings of the National Academy of Sciences ·Jason Howitt, Ulrich Putz, Jenny Lackovic, Anh Doan, Loretta Dorstyn, Hong Cheng, Baoli Yang, Tailoi Chan‐Ling, John Silke, Sharad Kumar, Seong‐Seng Tan	2009	97
12	Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability Cell Death and Differentiation ·Loretta Dorstyn, Joseph Puccini, C H Wilson, Sonia Shalini, Mario Nicola, Stephen P.G. Moore, Sharad Kumar	2012	83
13	Caspase-2 as a tumour suppressor Cell Death and Differentiation ·Joseph Puccini, Loretta Dorstyn, Sharad Kumar	2013	82
14	Characterization of the DrosophilaCaspase, DAMM Journal of Biological Chemistry ·Natasha L. Harvey, Tasman Daish, Kathryn Mills, Loretta Dorstyn, Leonie M. Quinn, Stuart H. Read, Helena E. Richardson, Sharad Kumar	2001	70
15	Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice Cell Death and Differentiation ·Sonia Shalini, Loretta Dorstyn, Christopher M. Wilson, Joseph Puccini, Lien H. Ho, Sharad Kumar	2012	70
16	Structure of the Drosophila Apoptosome at 6.9 Å Resolution Structure ·Shujun Yuan, Xinchao Yu, Maya Topf, Loretta Dorstyn, Sharad Kumar, Steven J. Ludtke, Christopher W. Akey	2011	63
17	Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm -deficient mice Proceedings of the National Academy of Sciences ·Joseph Puccini, Sonia Shalini, Anne K. Voss, Magtouf Gatei, Claire H. Wilson, Devendra Hiwase, Martin F. Lavin, Loretta Dorstyn, Sharad Kumar	2013	54
18	Caspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity Cell Death and Disease ·Claire H. Wilson, Andrej Nikolic, Stephen J. Kentish, Marianne Keller, George Hatzinikolas, Loretta Dorstyn, Amanda J. Page, Sharad Kumar	2017	50
19	Caspase-2-mediated cell death is required for deleting aneuploid cells Oncogene ·Swati Dawar, Yoon Lim, Joseph Puccini, Melissa White, Philip Thomas, Lisa Bouchier‐Hayes, Douglas R. Green, Loretta Dorstyn, Sharad Kumar	2016	49
20	ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis Cell Death and Differentiation ·Jarrod J. Sandow, Loretta Dorstyn, Lorraine A. O’Reilly, Maximilien Tailler, Sharad Kumar, Andreas Strasser, Paul G. Ekert	2013	48

About Loretta Dorstyn

Loretta Dorstyn is a scholar working on Aging, Molecular Biology, Cell Biology, Immunology and Hematology, having authored 46 papers that have together received 3.5k indexed citations. Recurring topics across this work include Cell death mechanisms and regulation (33 papers), Autophagy in Disease and Therapy (9 papers), interferon and immune responses (6 papers), Hippo pathway signaling and YAP/TAZ (5 papers), Trace Elements in Health (5 papers), Mitochondrial Function and Pathology (5 papers), PARP inhibition in cancer therapy (4 papers) and Cancer-related Molecular Pathways (4 papers). The work is most often cited by research in Aging (68 citations), Molecular Biology (2.5k citations), Immunology (748 citations), Cell Biology (515 citations) and Epidemiology (623 citations). Loretta Dorstyn has collaborated with scholars based in Australia, United States and United Kingdom. Frequent co-authors include Sharad Kumar, Sonia Shalini, Swati Dawar, Helena E. Richardson, Leonie M. Quinn, Stuart H. Read, Joseph Puccini, Christopher W. Akey, Paul A. Colussi and Lien H. Ho. Their work appears in journals such as Cell Death and Differentiation, Cell Death and Disease, Journal of Biological Chemistry, Proceedings of the National Academy of Sciences and Oncogene.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact