William J. Pitts

5.7k total citations · 2 hit papers
34 papers, 4.4k citations indexed

About

William J. Pitts is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, William J. Pitts has authored 34 papers receiving a total of 4.4k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 12 papers in Organic Chemistry and 6 papers in Oncology. Recurrent topics in William J. Pitts's work include Biochemical and Molecular Research (11 papers), Adenosine and Purinergic Signaling (5 papers) and Cytokine Signaling Pathways and Interactions (5 papers). William J. Pitts is often cited by papers focused on Biochemical and Molecular Research (11 papers), Adenosine and Purinergic Signaling (5 papers) and Cytokine Signaling Pathways and Interactions (5 papers). William J. Pitts collaborates with scholars based in United States, Sweden and Germany. William J. Pitts's co-authors include Ronald L. Magolda, Robert A. Copeland, James M. Trzăskos, Richard A. Earl, Peggy Scherle, Kurumi Y. Horiuchi, Drew E. Van Dyk, Elizabeth J. Manos, Margaret Favata and Frank W. Hobbs and has published in prestigious journals such as Science, Journal of Biological Chemistry and The Journal of Immunology.

In The Last Decade

William J. Pitts

34 papers receiving 4.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

1998 2.8k citations Margaret Favata, Kurumi Y. Horiuchi et al. Journal of Biological Chemistry profile →
Practical olefin hydroamination with nitroarenes

2015 452 citations Jinghan Gui, Ying Jin et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
William J. Pitts United States	20	2.4k	965	673	543	385	34	4.4k
Shripad S. Bhagwat United States	22	2.1k 0.9×	675 0.7×	611 0.9×	529 1.0×	290 0.8×	53	4.0k
Ronald L. Magolda United States	29	3.0k 1.3×	687 0.7×	950 1.4×	728 1.3×	480 1.2×	69	5.6k
Hervé Coste France	16	3.5k 1.5×	391 0.4×	465 0.7×	527 1.0×	494 1.3×	17	4.8k
Michiaki Kohno Japan	35	3.1k 1.3×	309 0.3×	846 1.3×	393 0.7×	340 0.9×	92	4.5k
Morten Frödin Denmark	28	3.9k 1.6×	364 0.4×	632 0.9×	323 0.6×	428 1.1×	42	4.8k
James F. Callahan United States	22	2.7k 1.1×	559 0.6×	691 1.0×	325 0.6×	150 0.4×	54	4.0k
Hilary McLauchlan United Kingdom	13	3.2k 1.3×	303 0.3×	775 1.2×	431 0.8×	537 1.4×	16	4.6k
Chikara Murakata Japan	25	1.7k 0.7×	478 0.5×	349 0.5×	243 0.4×	454 1.2×	43	2.7k
William F. Matter United States	14	3.1k 1.3×	222 0.2×	689 1.0×	749 1.4×	403 1.0×	19	4.5k
Christian A. Hassig United States	19	5.2k 2.2×	364 0.4×	977 1.5×	343 0.6×	298 0.8×	40	5.9k

Countries citing papers authored by William J. Pitts

Since Specialization

Citations

This map shows the geographic impact of William J. Pitts's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William J. Pitts with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William J. Pitts more than expected).

Fields of papers citing papers by William J. Pitts

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William J. Pitts. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William J. Pitts. The network helps show where William J. Pitts may publish in the future.

Co-authorship network of co-authors of William J. Pitts

This figure shows the co-authorship network connecting the top 25 collaborators of William J. Pitts. A scholar is included among the top collaborators of William J. Pitts based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William J. Pitts. William J. Pitts is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bhide, Rajeev S., Carolyn A. Weigelt, John S. Sack, et al.. (2017). Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors. Bioorganic & Medicinal Chemistry Letters. 27(21). 4908–4913. 17 indexed citations

Gui, Jinghan, Ying Jin, Tian Qin, et al.. (2015). Practical olefin hydroamination with nitroarenes. Science. 348(6237). 886–891. 452 indexed citations breakdown →

Tokarski, John S., Adriana Zupa-Fernandez, Jeffrey Tredup, et al.. (2015). Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain. Journal of Biological Chemistry. 290(17). 11061–11074. 84 indexed citations

Spergel, Steven H., et al.. (2010). One-Pot Synthesis of Azaindoles via Palladium-Catalyzed α-Heteroarylation of Ketone Enolates. The Journal of Organic Chemistry. 75(15). 5316–5319. 27 indexed citations

Kempson, James, Junqing Guo, Jagabandhu Das, et al.. (2009). Synthesis, initial SAR and biological evaluation of 1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-amine derived inhibitors of IκB kinase. Bioorganic & Medicinal Chemistry Letters. 19(10). 2646–2649. 16 indexed citations

Duan, James J.‐W., Lihua Chen, Zhonghui Lu, et al.. (2006). Discovery of low nanomolar non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE). Bioorganic & Medicinal Chemistry Letters. 17(1). 266–271. 45 indexed citations

Kim, Soong‐Hoon, Andrew T. Pudzianowski, Kenneth J. Leavitt, et al.. (2005). Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13). Bioorganic & Medicinal Chemistry Letters. 15(4). 1101–1106. 80 indexed citations

Pitts, William J., Wayne Vaccaro, Tram Huynh, et al.. (2004). Identification of purine inhibitors of phosphodiesterase 7 (PDE7). Bioorganic & Medicinal Chemistry Letters. 14(11). 2955–2958. 38 indexed citations

McIntyre, Kim W., Henry Shen, William J. Pitts, et al.. (2003). Phosphodiesterase 7A-Deficient Mice Have Functional T Cells. The Journal of Immunology. 171(12). 6414–6420. 79 indexed citations

10.

Chen, Ping, Derek Norris, T. G. Murali Dhar, et al.. (2003). Identification of novel and potent isoquinoline aminooxazole-Based IMPDH inhibitors. Bioorganic & Medicinal Chemistry Letters. 13(7). 1345–1348. 21 indexed citations

11.

Watterson, Scott H., T. G. Murali Dhar, Zhongqi Shen, et al.. (2003). Novel inhibitors of IMPDH. Bioorganic & Medicinal Chemistry Letters. 13(3). 543–546. 23 indexed citations

12.

Dhar, T. G. Murali, Scott H. Watterson, Ping Chen, et al.. (2003). Quinolone-Based IMPDH inhibitors: introduction of basic residues on ring D and SAR of the corresponding mono, di and benzofused analogues. Bioorganic & Medicinal Chemistry Letters. 13(3). 547–551. 7 indexed citations

13.

Iwanowicz, Edwin J., Scott H. Watterson, Junqing Guo, et al.. (2003). Inhibitors of inosine monophosphate dehydrogenase: SARs about the N-[3-Methoxy-4-(5-oxazolyl)phenyl moiety. Bioorganic & Medicinal Chemistry Letters. 13(12). 2059–2063. 18 indexed citations

14.

Pitts, William J., Junqing Guo, T. G. Murali Dhar, et al.. (2002). Rapid synthesis of triazine inhibitors of inosine monophosphate dehydrogenase. Bioorganic & Medicinal Chemistry Letters. 12(16). 2137–2140. 31 indexed citations

15.

Watterson, Scott H., Chunjian Liu, T. G. Murali Dhar, et al.. (2002). Novel amide-based inhibitors of inosine 5′-monophosphate dehydrogenase. Bioorganic & Medicinal Chemistry Letters. 12(20). 2879–2882. 11 indexed citations

16.

Salih, Helmut R., Gary C. Starling, Markus Knauff, et al.. (2001). Retinoic Acid and Vitamin E Modulate Expression and Release of CD178 in Carcinoma Cells: Consequences for Induction of Apoptosis in CD95-Sensitive Cells. Experimental Cell Research. 270(2). 248–258. 9 indexed citations

17.

Rockwell, Arlene L., Maria Rafalski, William J. Pitts, et al.. (1999). Rapid synthesis of RGD mimetics with isoxazoline scaffolds on solid phase: Identification of αvβ3 antagonists lead compounds. Bioorganic & Medicinal Chemistry Letters. 9(7). 937–942. 22 indexed citations

18.

Pinto, Donald, Douglas G. Batt, William J. Pitts, et al.. (1999). Terphenyl cyclooxygenase-2 (COX-2) inhibitors: Optimization of the central ring and o-biphenyl analogs. Bioorganic & Medicinal Chemistry Letters. 9(7). 919–924. 17 indexed citations

19.

Favata, Margaret, Kurumi Y. Horiuchi, Elizabeth J. Manos, et al.. (1998). Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase. Journal of Biological Chemistry. 273(29). 18623–18632. 2750 indexed citations breakdown →

20.

Pitts, William J., James W. Jetter, Donald Pinto, et al.. (1998). Structure-activity relationships (SAR) of some tetracyclic heterocycles related to the immunosuppressive agent brequinar sodium. Bioorganic & Medicinal Chemistry Letters. 8(3). 307–312. 15 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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