Steven H. Spergel

2.2k citations

26 papers · 1.0k indexed · 1 hit paper · h-index 16

Co-authors: William J. Pitts Joel C. Barrish Thomas E. La Cruz Tian Qin Ying Jin Michael Mertzman S. Natarajan Michael A. Schmidt
Topics: Quinazolinone synthesis and applications (3 papers)Melanoma and MAPK Pathways (3 papers)HIV/AIDS drug development and treatment (3 papers)
Cited by: Organic Chemistry Inorganic Chemistry Toxicology
Journals: Science Journal of Medicinal Chemistry The Journal of Organic Chemistry
Partner nations: United States Germany Sweden

In The Last Decade

Steven H. Spergel

26 papers receiving 1.0k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Practical olefin hydroamination with nitroarenes

2015 452 citations Jinghan Gui, Ying Jin et al. Science profile →

Peers

Countries citing papers authored by Steven H. Spergel

Since Specialization

Citations

This map shows the geographic impact of Steven H. Spergel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven H. Spergel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven H. Spergel more than expected).

Fields of papers citing papers by Steven H. Spergel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven H. Spergel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven H. Spergel. The network helps show where Steven H. Spergel may publish in the future.

Co-authorship network of co-authors of Steven H. Spergel

This figure shows the co-authorship network connecting the top 25 collaborators of Steven H. Spergel. A scholar is included among the top collaborators of Steven H. Spergel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Steven H. Spergel. Steven H. Spergel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors 2017 ·Bioorganic & Medicinal Chemistry Letters ·Rajeev S. Bhide,(unknown),Carolyn A. Weigelt,John S. Sack,Robert J. Schmidt,Shuqun Lin,Hai‐Yun Xiao,Steven H. Spergel,James Kempson,William J. Pitts,Julie Carman,Michael A. Poss	17
2	Practical olefin hydroamination with nitroarenesbreakdown → 2015 ·Science ·Jinghan Gui,(unknown),Ying Jin,Tian Qin,Julian C. Lo,(unknown),Steven H. Spergel,Michael Mertzman,William J. Pitts,Thomas E. La Cruz,Michael A. Schmidt,Nitin B. Darvatkar,S. Natarajan,Phil S. Baran	452
3	One-Pot Synthesis of Azaindoles via Palladium-Catalyzed α-Heteroarylation of Ketone Enolates 2010 ·The Journal of Organic Chemistry ·Steven H. Spergel,(unknown),William J. Pitts	27
4	Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: Synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritis 2010 ·Bioorganic & Medicinal Chemistry Letters ·Alaric J. Dyckman,Charles M. Langevine,Claude Quesnelle,James Kempson,Junqing Guo,Patrice Gill,Steven H. Spergel,Scott H. Watterson,Tianle Li,David S. Nirschl,Kathleen M. Gillooly,Mark A. Pattoli,Kim W. McIntyre,(unknown),Murray McKinnon,John H. Dodd,Joel C. Barrish,James R. Burke,William J. Pitts	7
5	Synthesis, initial SAR and biological evaluation of 1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-amine derived inhibitors of IκB kinase 2009 ·Bioorganic & Medicinal Chemistry Letters ·James Kempson,Junqing Guo,Jagabandhu Das,Robert V. Moquin,Steven H. Spergel,Scott H. Watterson,Charles M. Langevine,Alaric J. Dyckman,Mark A. Pattoli,James R. Burke,Xiao-Xia Yang,Kathleen M. Gillooly,Kim W. McIntyre,(unknown),John H. Dodd,Murray McKinnon,Joel C. Barrish,William J. Pitts	16
6	Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors 2006 ·Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das,(unknown),Chunjian Liu,Robert V. Moquin,James C. Lin,Steven H. Spergel,Kim W. McIntyre,David J. Shuster,Kathleen O'Day,Becky Penhallow,(unknown),Arthur M. Doweyko,Amrita V. Kamath,Hongjian Zhang,Punit Marathe,Steven B. Kanner,Tai-An Lin,John H. Dodd,Joel C. Barrish,John Wityak	64
7	Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors 2006 ·Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das,Chunjian Liu,Robert V. Moquin,James C. Lin,(unknown),Steven H. Spergel,Kim W. McIntyre,David J. Shuster,Kathleen O'Day,Becky Penhallow,(unknown),Steven B. Kanner,Tai-An Lin,John H. Dodd,Joel C. Barrish,John Wityak	31
8	Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56Lck inhibitors 2004 ·Bioorganic & Medicinal Chemistry Letters ·Ping Chen,Derek Norris,Jagabandhu Das,Steven H. Spergel,John Wityak,Leslie Leith,Rui-Lin Zhao,Bang‐Chi Chen,Sidney Pitt,Suhong Pang,Ding Ren Shen,Rosemary Zhang,H. Fex,Arthur M. Doweyko,Kim W. McIntyre,David J. Shuster,Kamelia Behnia,Gary L. Schieven,Joel C. Barrish	22
9	Molecular design, synthesis, and structure–Activity relationships leading to the potent and selective p56lck inhibitor BMS-243117 2003 ·Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das,James C. Lin,Robert V. Moquin,Zhongqi Shen,Steven H. Spergel,John Wityak,Arthur M. Doweyko,(unknown),Qiong Fang,Suhong Pang,Sidney Pitt,Ding Ren Shen,Gary L. Schieven,Joel C. Barrish	47
10	Rational Design and Synthesis of an Orally Active Indolopyridone as a Novel Conformationally Constrained Cannabinoid Ligand Possessing Antiinflammatory Properties 2003 ·Journal of Medicinal Chemistry ·Stephen T. Wrobleski,Ping Chen,John Hynes,Shuqun Lin,Derek Norris,Chennagiri R. Pandit,Steven H. Spergel,Wu Hong,John S. Tokarski,Xiaorong Chen,Kathleen M. Gillooly,Peter A. Kiener,Kim W. McIntyre,(unknown),David J. Shuster,(unknown),(unknown),Katerina Leftheris	52
11	Biphenylsulfonamide Endothelin Receptor Antagonists. Part 3: Structure–Activity Relationship of 4′-Heterocyclic Biphenylsulfonamides 2002 ·Bioorganic & Medicinal Chemistry Letters ·Natesan Murugesan,Zhengxiang Gu,Philip D. Stein,Steven H. Spergel,(unknown),Eddie C.‐K. Liu,Rongan Zhang,Maria L. Webb,Suzanne Moreland,Joel C. Barrish	3
12	Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56Lck 2002 ·Bioorganic & Medicinal Chemistry Letters ·Ping Chen,Derek Norris,Edwin J. Iwanowicz,Steven H. Spergel,James C. Lin,Henry H. Gu,Zhongqi Shen,John Wityak,Tai-An Lin,Suhong Pang,H. Fex,Sidney Pitt,Ding Ren Shen,Arthur M. Doweyko,Donna A. Bassolino,Jacques Y. Roberge,Michael A. Poss,Bang‐Chi Chen,Gary L. Schieven,Joel C. Barrish	28
13	Synthesis and SAR of novel imidazoquinoxaline-Based Lck inhibitors: improvement of cell potency 2002 ·Bioorganic & Medicinal Chemistry Letters ·Ping Chen,Edwin J. Iwanowicz,Derek Norris,Henry H. Gu,James C. Lin,Robert V. Moquin,Jagabandhu Das,John Wityak,Steven H. Spergel,(unknown),Suhong Pang,(unknown),Ding Ren Shen,Gary L. Schieven,Joel C. Barrish	13
14	Biphenylsulfonamide Endothelin Receptor Antagonists. 2. Discovery of 4‘-Oxazolyl Biphenylsulfonamides as a New Class of Potent, Highly Selective ET_A Antagonists 2000 ·Journal of Medicinal Chemistry ·Natesan Murugesan,Zhengxiang Gu,Philip D. Stein,Steven H. Spergel,Arvind Mathur,Leslie Leith,Eddie C.‐K. Liu,Rongan Zhang,(unknown),(unknown),Anthony M. Marino,Richard A. Morrison,Maria L. Webb,Suzanne Moreland,Joel C. Barrish	24
15	A practical method for the preparation of α′-chloroketones of N-carbamate protected-α-aminoacids 1997 ·Tetrahedron Letters ·(unknown),Peter T. W. Cheng,Steven H. Spergel,Robert Zahler,Xuebao Wang,John K. Thottathil,Joel C. Barrish,Richard P. Polniaszek	38
16	α-hydroxyamide derived aminodiols as potent inhibitors of hiv protease 1995 ·Bioorganic & Medicinal Chemistry Letters ·Saleem Ahmad,(unknown),Masud Alam,Gregory S. Bisacchi,Ping Chen,Peter T. W. Cheng,(unknown),Mark A. Hermsmeier,Pin-Fang Lin,(unknown),(unknown),Toomas Mitt,Mark T. Skoog,Steven H. Spergel,Joseph A. Tino,Gregory D. Vite,Richard J. Colonno,Robert Zahler,Joel C. Barrish	9
17	Synthesis and antiviral activity of novel isonucleoside analogs 1993 ·Journal of Medicinal Chemistry ·Joseph A. Tino,Junius M. Clark,Anjalie Field,G. A. JACOBS,(unknown),(unknown),(unknown),William A. Slusarchyk,Steven H. Spergel	46
18	1-benzazepin-2-one calcium channel blockers—VI. Receptor-binding model and possible relationship to desmethoxyverapamil. 1993 ·Bioorganic & Medicinal Chemistry ·S. David Kimball,John T. Hunt,Joel C. Barrish,Jagabandhu Das,David Floyd,Michael W. Lago,Ving G. Lee,Steven H. Spergel,Suzanne Moreland,(unknown),Jack Z. Gougoutas,Mary F. Malley,(unknown)	11
19	Conformationally constrained calcium channel blockers: Novel mimics of 1-benzazepin-2-ones 1993 ·Bioorganic & Medicinal Chemistry ·Joel C. Barrish,Steven H. Spergel,Suzanne Moreland,Gary J. Grover,(unknown),Andrew T. Pudzianowski,Jack Z. Gougoutas,Mary F. Malley	6
20	Stereoelectronic effects in nucleophilic addition to a bicyclic ketone: an interpretation 1992 ·Tetrahedron Letters ·Andrew T. Pudzianowski,Joel C. Barrish,Steven H. Spergel	16

About Steven H. Spergel

Steven H. Spergel is a scholar working on Organic Chemistry, Toxicology and Virology, having authored 26 papers that have together received 1.0k indexed citations. Recurring topics across this work include Quinazolinone synthesis and applications (3 papers), Melanoma and MAPK Pathways (3 papers) and HIV/AIDS drug development and treatment (3 papers). The work is most often cited by research in Organic Chemistry (787 citations), Inorganic Chemistry (188 citations) and Toxicology (26 citations). Steven H. Spergel has collaborated with scholars based in United States, Germany and Sweden. Frequent co-authors include William J. Pitts, Joel C. Barrish, Thomas E. La Cruz, Tian Qin, Ying Jin, Michael Mertzman, S. Natarajan, Michael A. Schmidt, Phil S. Baran and Nitin B. Darvatkar. Their work appears in journals such as Science, Journal of Medicinal Chemistry and The Journal of Organic Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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