Steven H. Spergel

2.2k citations

26 papers · 1.0k indexed · 1 hit paper · h-index 16

Organic Chemistry top 2%
- Quinazolinone synthesis and applications 3
- Chemical synthesis and alkaloids 3
- Synthesis and Biological Evaluation 3
- Click Chemistry and Applications 2
Inorganic Chemistry top 10%
Toxicology top 10%
Process Chemistry and Technology
Pharmaceutical Science
Molecular Biology
- Melanoma and MAPK Pathways 3
Infectious Diseases
- HIV/AIDS drug development and treatment 3
Cancer Research
- NF-κB Signaling Pathways 3
Physiology
- Nitric Oxide and Endothelin Effects 2

Co-authors: William J. Pitts Joel C. Barrish Thomas E. La Cruz Tian Qin Ying Jin Michael Mertzman S. Natarajan Michael A. Schmidt
Cited by: Organic Chemistry Inorganic Chemistry Toxicology
Journals: Science (1 paper)Journal of Medicinal Chemistry (3 papers)The Journal of Organic Chemistry (3 papers)
Partner nations: United States Germany Sweden

In The Last Decade

Steven H. Spergel

26 papers receiving 1.0k citations

Hit Papers

align trajectories log scale

Peers

Countries citing papers authored by Steven H. Spergel

Since Specialization

Citations

This map shows the geographic impact of Steven H. Spergel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven H. Spergel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven H. Spergel more than expected).

Fields of papers citing papers by Steven H. Spergel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven H. Spergel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven H. Spergel. The network helps show where Steven H. Spergel may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Steven H. Spergel, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Steven H. Spergel Line = papers co-authored together Steven H. Spergel links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors Bioorganic & Medicinal Chemistry Letters ·Rajeev S. Bhide,Alec E. Keon,Carolyn A. Weigelt,John S. Sack,Robert J. Schmidt,Shuqun Lin,Hai‐Yun Xiao,Steven H. Spergel,James Kempson,William J. Pitts,Julie Carman,Michael A. Poss	2017	17
2	Practical olefin hydroamination with nitroarenesbreakdown → Science ·Jinghan Gui,Chung-Mao Pan,Ying Jin,Tian Qin,Julian C. Lo,Bryan J. Lee,Steven H. Spergel,Michael Mertzman,William J. Pitts,Thomas E. La Cruz,Michael A. Schmidt,Nitin B. Darvatkar,S. Natarajan,Phil S. Baran	2015	452
3	One-Pot Synthesis of Azaindoles via Palladium-Catalyzed α-Heteroarylation of Ketone Enolates The Journal of Organic Chemistry ·Steven H. Spergel,Danielle R. Okoro,William J. Pitts	2010	27
4	Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: Synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritis Bioorganic & Medicinal Chemistry Letters ·Alaric J. Dyckman,Charles M. Langevine,Claude Quesnelle,James Kempson,Junqing Guo,Patrice Gill,Steven H. Spergel,Scott H. Watterson,Tianle Li,David S. Nirschl,Kathleen M. Gillooly,Mark A. Pattoli,Kim W. McIntyre,Laishun Chen,Murray McKinnon,John H. Dodd,Joel C. Barrish,James R. Burke,William J. Pitts	2010	7
5	Synthesis, initial SAR and biological evaluation of 1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-amine derived inhibitors of IκB kinase Bioorganic & Medicinal Chemistry Letters ·James Kempson,Junqing Guo,Jagabandhu Das,Robert V. Moquin,Steven H. Spergel,Scott H. Watterson,Charles M. Langevine,Alaric J. Dyckman,Mark A. Pattoli,James R. Burke,Xiao-Xia Yang,Kathleen M. Gillooly,Kim W. McIntyre,Laishun Chen,John H. Dodd,Murray McKinnon,Joel C. Barrish,William J. Pitts	2009	16
6	Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das,Joseph A. Furch,Chunjian Liu,Robert V. Moquin,James C. Lin,Steven H. Spergel,Kim W. McIntyre,David J. Shuster,Kathleen O'Day,Becky Penhallow,Chen-Yi Hung,Arthur M. Doweyko,Amrita V. Kamath,Hongjian Zhang,Punit Marathe,Steven B. Kanner,Tai-An Lin,John H. Dodd,Joel C. Barrish,John Wityak	2006	64
7	Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das,Chunjian Liu,Robert V. Moquin,James C. Lin,Joseph A. Furch,Steven H. Spergel,Kim W. McIntyre,David J. Shuster,Kathleen O'Day,Becky Penhallow,Chen-Yi Hung,Steven B. Kanner,Tai-An Lin,John H. Dodd,Joel C. Barrish,John Wityak	2006	31
8	Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56Lck inhibitors Bioorganic & Medicinal Chemistry Letters ·Ping Chen,Derek Norris,Jagabandhu Das,Steven H. Spergel,John Wityak,Leslie Leith,Rui-Lin Zhao,Bang‐Chi Chen,Sidney Pitt,Suhong Pang,Ding Ren Shen,Rosemary Zhang,H. Fex,Arthur M. Doweyko,Kim W. McIntyre,David J. Shuster,Kamelia Behnia,Gary L. Schieven,Joel C. Barrish	2004	22
9	Molecular design, synthesis, and structure–Activity relationships leading to the potent and selective p56lck inhibitor BMS-243117 Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das,James C. Lin,Robert V. Moquin,Zhongqi Shen,Steven H. Spergel,John Wityak,Arthur M. Doweyko,Henry F. DeFex,Qiong Fang,Suhong Pang,Sidney Pitt,Ding Ren Shen,Gary L. Schieven,Joel C. Barrish	2003	47
10	Rational Design and Synthesis of an Orally Active Indolopyridone as a Novel Conformationally Constrained Cannabinoid Ligand Possessing Antiinflammatory Properties Journal of Medicinal Chemistry ·Stephen T. Wrobleski,Ping Chen,John Hynes,Shuqun Lin,Derek Norris,Chennagiri R. Pandit,Steven H. Spergel,Wu Hong,John S. Tokarski,Xiaorong Chen,Kathleen M. Gillooly,Peter A. Kiener,Kim W. McIntyre,Vina Patil-koota,David J. Shuster,Lori A. Turk,Guchen Yang,Katerina Leftheris	2003	52
11	Biphenylsulfonamide Endothelin Receptor Antagonists. Part 3: Structure–Activity Relationship of 4′-Heterocyclic Biphenylsulfonamides Bioorganic & Medicinal Chemistry Letters ·Natesan Murugesan,Zhengxiang Gu,Philip D. Stein,Steven H. Spergel,Sharon N. Bisaha,Eddie C.‐K. Liu,Rongan Zhang,Maria L. Webb,Suzanne Moreland,Joel C. Barrish	2002	3
12	Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56Lck Bioorganic & Medicinal Chemistry Letters ·Ping Chen,Derek Norris,Edwin J. Iwanowicz,Steven H. Spergel,James C. Lin,Henry H. Gu,Zhongqi Shen,John Wityak,Tai-An Lin,Suhong Pang,H. Fex,Sidney Pitt,Ding Ren Shen,Arthur M. Doweyko,Donna A. Bassolino,Jacques Y. Roberge,Michael A. Poss,Bang‐Chi Chen,Gary L. Schieven,Joel C. Barrish	2002	28
13	Synthesis and SAR of novel imidazoquinoxaline-Based Lck inhibitors: improvement of cell potency Bioorganic & Medicinal Chemistry Letters ·Ping Chen,Edwin J. Iwanowicz,Derek Norris,Henry H. Gu,James C. Lin,Robert V. Moquin,Jagabandhu Das,John Wityak,Steven H. Spergel,Henry de Fex,Suhong Pang,Sydney Pitt,Ding Ren Shen,Gary L. Schieven,Joel C. Barrish	2002	13
14	Biphenylsulfonamide Endothelin Receptor Antagonists. 2. Discovery of 4‘-Oxazolyl Biphenylsulfonamides as a New Class of Potent, Highly Selective ET_A Antagonists Journal of Medicinal Chemistry ·Natesan Murugesan,Zhengxiang Gu,Philip D. Stein,Steven H. Spergel,Arvind Mathur,Leslie Leith,Eddie C.‐K. Liu,Rongan Zhang,Eileen Bird,Tom Waldron,Anthony M. Marino,Richard A. Morrison,Maria L. Webb,Suzanne Moreland,Joel C. Barrish	2000	24
15	A practical method for the preparation of α′-chloroketones of N-carbamate protected-α-aminoacids Tetrahedron Letters ·Ping Chen,Peter T. W. Cheng,Steven H. Spergel,Robert Zahler,Xuebao Wang,John K. Thottathil,Joel C. Barrish,Richard P. Polniaszek	1997	38
16	α-hydroxyamide derived aminodiols as potent inhibitors of hiv protease Bioorganic & Medicinal Chemistry Letters ·Saleem Ahmad,Aaila Ashfaq,Masud Alam,Gregory S. Bisacchi,Ping Chen,Peter T. W. Cheng,Jill A. Greytok,Mark A. Hermsmeier,Pin-Fang Lin,Karen A. Lis,Z. Merchant,Toomas Mitt,Mark T. Skoog,Steven H. Spergel,Joseph A. Tino,Gregory D. Vite,Richard J. Colonno,Robert Zahler,Joel C. Barrish	1995	9
17	Synthesis and antiviral activity of novel isonucleoside analogs Journal of Medicinal Chemistry ·Joseph A. Tino,Junius M. Clark,Anjalie Field,G. A. JACOBS,Karen A. Lis,T Michalik,B. McGeever-Rubin,William A. Slusarchyk,Steven H. Spergel	1993	46
18	1-benzazepin-2-one calcium channel blockers—VI. Receptor-binding model and possible relationship to desmethoxyverapamil. Bioorganic & Medicinal Chemistry ·S. David Kimball,John T. Hunt,Joel C. Barrish,Jagabandhu Das,David Floyd,Michael W. Lago,Ving G. Lee,Steven H. Spergel,Suzanne Moreland,S.Anders Hedberg,Jack Z. Gougoutas,Mary F. Malley,Wan F. Lau	1993	11
19	Conformationally constrained calcium channel blockers: Novel mimics of 1-benzazepin-2-ones Bioorganic & Medicinal Chemistry ·Joel C. Barrish,Steven H. Spergel,Suzanne Moreland,Gary J. Grover,S.Anders Hedberg,Andrew T. Pudzianowski,Jack Z. Gougoutas,Mary F. Malley	1993	6
20	Stereoelectronic effects in nucleophilic addition to a bicyclic ketone: an interpretation Tetrahedron Letters ·Andrew T. Pudzianowski,Joel C. Barrish,Steven H. Spergel	1992	16

About Steven H. Spergel

Steven H. Spergel is a scholar working on Organic Chemistry, Toxicology and Virology, having authored 26 papers that have together received 1.0k indexed citations. Recurring topics across this work include Quinazolinone synthesis and applications (3 papers), Melanoma and MAPK Pathways (3 papers), HIV/AIDS drug development and treatment (3 papers), Chemical synthesis and alkaloids (3 papers), NF-κB Signaling Pathways (3 papers), Synthesis and Biological Evaluation (3 papers), Nitric Oxide and Endothelin Effects (2 papers) and Click Chemistry and Applications (2 papers). The work is most often cited by research in Organic Chemistry (787 citations), Inorganic Chemistry (188 citations) and Toxicology (26 citations). Steven H. Spergel has collaborated with scholars based in United States, Germany and Sweden. Frequent co-authors include William J. Pitts, Joel C. Barrish, Thomas E. La Cruz, Tian Qin, Ying Jin, Michael Mertzman, S. Natarajan, Michael A. Schmidt, Phil S. Baran and Nitin B. Darvatkar. Their work appears in journals such as Science, Journal of Medicinal Chemistry and The Journal of Organic Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact