James R. Burke

4.2k citations

55 papers · 2.3k indexed · h-index 24

Cancer Research top 2%
- NF-κB Signaling Pathways 16
Immunology top 5%
- Immune Response and Inflammation 10
Oncology top 5%
- Cytokine Signaling Pathways and Interactions 11
Molecular Biology top 10%
- Protein Kinase Regulation and GTPase Signaling 10
- PI3K/AKT/mTOR signaling in cancer 4
- Lipid Membrane Structure and Behavior 3
Toxicology top 5%
Genetics
- Chronic Lymphocytic Leukemia Research 8
Cell Biology
- Cellular transport and secretion 6

Co-authors: Joann Strnad Kurt R. Gregor Mark A. Pattoli Yuping Qiu F. Christopher Zusi Kim W. McIntyre John F. MacMaster Patrick Brassil
Cited by: Cancer Research Immunology Oncology
Journals: Journal of the American Chemical Society (1 paper)Journal of Biological Chemistry (6 papers)Nature Medicine (1 paper)
Partner nations: United States Germany Australia

In The Last Decade

James R. Burke

54 papers receiving 2.3k citations

Peers

Countries citing papers authored by James R. Burke

Since Specialization

Citations

This map shows the geographic impact of James R. Burke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James R. Burke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James R. Burke more than expected).

Fields of papers citing papers by James R. Burke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James R. Burke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James R. Burke. The network helps show where James R. Burke may publish in the future.

Co-authorship network

The 25 scholars most cited alongside James R. Burke, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James R. Burke Line = papers co-authored together James R. Burke links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A High-Throughput BRET Cellular Target Engagement Assay Links Biochemical to Cellular Activity for Bruton’s Tyrosine Kinase SLAS DISCOVERY ·Lianne Ong,James D. Vasta,Laura Monereau,Gregory Locke,Humberto Ribeiro,Mark A. Pattoli,Stacey Skala,James R. Burke,Scott H. Watterson,Joseph A. Tino,Poncho Meisenheimer,Brian J. Arey,Jonathan Lippy,L. Zhang,Matthew B. Robers,Andrew J. Tebben,Charu Chaudhry	2019	9
2	Bruton's tyrosine kinase inhibitor BMS-986142 in experimental models of rheumatoid arthritis enhances efficacy of agents representing clinical standard-of-care PLoS ONE ·Kathleen M. Gillooly,Claudine Pulicicchio,Mark A. Pattoli,Lihong Cheng,Stacey Skala,Elizabeth Heimrich,Kim W. McIntyre,Tracy Taylor,Daniel Kukral,Shailesh Dudhgaonkar,Jignesh Nagar,Dana Banas,Scott H. Watterson,Joseph A. Tino,Aberra Fura,James R. Burke	2017	47
3	Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain Journal of Biological Chemistry ·John S. Tokarski,Adriana Zupa-Fernandez,Jeffrey Tredup,Kristen Pike,ChiehYing Y. Chang,Dianlin Xie,Lihong Cheng,Donna L. Pedicord,J.K. Muckelbauer,Stephen R. Johnson,Sophie Wu,Suzanne C. Edavettal,Hong Yang,Mark R. Witmer,Lisa Elkin,Yuval Blat,William J. Pitts,David S. Weinstein,James R. Burke	2015	84
4	ASSESSMENT OF THE DIFFERENCES IN PHARMACOKINETICS AND PHARMACODYNAMICS BETWEEN FOUR DISTINCT FORMULATIONS OF TRIAMCINOLONE ACETONIDE Retina ·Leandro Cabral Zacharias,Ton Lin,Rafael Migon,Corine Ghosn,Werhner Orilla,Barbara Feldmann,Guadalupe Ruíz,Yong Li,James R. Burke,Baruch D. Kuppermann	2012	34
5	Caspase-2-Mediated Cleavage of Mdm2 Creates a p53-Induced Positive Feedback Loop Molecular Cell ·Trudy G. Oliver,Etienne Meylan,Gregory P. Chang,Wen Xue,James R. Burke,Timothy J. Humpton,Diana Hubbard,Arjun Bhutkar,Tyler Jacks	2011	120
6	Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer Genes & Development ·Trudy G. Oliver,Kim L. Mercer,Leanne C. Sayles,James R. Burke,Diana Mendus,Katherine S. Lovejoy,Mei-Hsin Cheng,Aravind Subramanian,David Mu,Scott Powers,Denise Crowley,Roderick T. Bronson,Charles A. Whittaker,Arjun Bhutkar,Stephen J. Lippard,Todd R. Golub,Jüergen Thomale,Tyler Jacks,E. Alejandro Sweet‐Cordero	2010	7
7	IκB kinase inhibitors for treating autoimmune and inflammatory disorders: potential and challenges Trends in Pharmacological Sciences ·Joann Strnad,James R. Burke	2007	73
8	Synthesis and structure–activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-β inhibitors Bioorganic & Medicinal Chemistry Letters ·Makonen Belema,Amy Bunker,Van N. Nguyen,Françis Beaulieu,Carl Ouellet,Yuping Qiu,Yunhui Zhang,Alain Martel,James R. Burke,Kim W. McIntyre,Mark A. Pattoli,Connie Daloisio,Kathleen M. Gillooly,Wendy Clarke,Patrick Brassil,F. Chris Zusi,Dolatrai M. Vyas	2007	26
9	Duration and Intensity of NF-κB Activity Determine the Severity of Endotoxin-Induced Acute Lung Injury The Journal of Immunology ·M. Brett Everhart,Wei Han,Taylor P. Sherrill,Melissa Arutiunov,Vasiliy V. Polosukhin,James R. Burke,Ruxana T. Sadikot,John W. Christman,Fiona E. Yull,Timothy S. Blackwell	2006	199
10	Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors Bioorganic & Medicinal Chemistry Letters ·Françis Beaulieu,Carl Ouellet,Edward H. Ruediger,Makonen Belema,Yuping Qiu,Xuejie Yang,Jacques Banville,James R. Burke,Kurt R. Gregor,John F. MacMaster,Alain Martel,Kim W. McIntyre,Mark A. Pattoli,F. Christopher Zusi,Dolatrai M. Vyas	2006	45
11	NEMO binding domain of IKK‐2 encompasses amino acids 735–745 Journal of Molecular Recognition ·Joann Strnad,Patricia A. McDonnell,Douglas J. Riexinger,Claudio Mapelli,Lihong Cheng,Hilary Gray,Rolf Ryseck,James R. Burke	2006	10
12	A HIGHLY SELECTIVE INHIBITOR OF IκB KINASE, BMS-345541, AUGMENTS GRAFT SURVIVAL MEDIATED BY SUBOPTIMAL IMMUNOSUPPRESSION IN A MURINE MODEL OF CARDIAC GRAFT REJECTION Transplantation ·Robert M. Townsend,Jennifer Postelnek,Vojkan Susulic,Kim W. McIntyre,David J. Shuster,Yuping Qiu,F. Christopher Zusi,James R. Burke	2004	20
13	The catalytic subunits of IκB kinase, IKK-1 and IKK-2, contain non-equivalent active sites when expressed as homodimers Biochemical and Biophysical Research Communications ·James R. Burke,Joann Strnad	2002	6
14	Cytosolic Phospholipase A2 Shows Burst Kinetics Consistent with the Slow, Reversible Formation of a Dead-End Complex Archives of Biochemistry and Biophysics ·Matthew G. Guenther,Mark R. Witmer,James R. Burke	2002	3
15	The Size and Curvature of Anionic Covesicle Substrate Affects the Catalytic Action of Cytosolic Phospholipase A2 Archives of Biochemistry and Biophysics ·James R. Burke,Mark R. Witmer,Jeffrey Tredup	1999	13
16	Differentiation of U937 Cells Enables a Phospholipase D-Dependent Pathway of Cytosolic Phospholipase A2 Activation Biochemical and Biophysical Research Communications ·James R. Burke,Lynda B. Davern,Kurt R. Gregor,Lisa M. Owczarczak	1999	13
17	Peptides Corresponding to the N and C Termini of IκB-α, -β, and -ε as Probes of the Two Catalytic Subunits of IκB Kinase, IKK-1 and IKK-2 Journal of Biological Chemistry ·James R. Burke,Marcia K. Wood,Rolf-Peter Ryseck,Susan Walther,Chester A. Meyers	1999	13
18	A β-Lactam Inhibitor of Cytosolic Phospholipase A₂which Acts in a Competitive, Reversible Manner at the Lipid/Water Interface Journal of enzyme inhibition ·James R. Burke,Kurt R. Gregor,Ramesh Padmanabha,Jacques Banville,Mark R. Witmer,Lynda B. Davern,Susan P. Manly,Kenneth M. Tramposch	1998	2
19	The Multisubunit IκB Kinase Complex Shows Random Sequential Kinetics and Is Activated by the C-terminal Domain of IκBα Journal of Biological Chemistry ·James R. Burke,Kenneth R. Miller,Marcia K. Wood,Chester A. Meyers	1998	30
20	4-(Oxoalkyl)-Substituted Gaba Analogues as Inactivators and Substrates of Gaba Aminotransferase Journal of enzyme inhibition ·James R. Burke,Richard B. Silverman	1991	2

About James R. Burke

James R. Burke is a scholar working on Cancer Research, Genetics and Immunology, having authored 55 papers that have together received 2.3k indexed citations. Recurring topics across this work include NF-κB Signaling Pathways (16 papers), Cytokine Signaling Pathways and Interactions (11 papers), Protein Kinase Regulation and GTPase Signaling (10 papers), Immune Response and Inflammation (10 papers), Chronic Lymphocytic Leukemia Research (8 papers), Cellular transport and secretion (6 papers), PI3K/AKT/mTOR signaling in cancer (4 papers) and Lipid Membrane Structure and Behavior (3 papers). The work is most often cited by research in Cancer Research (740 citations), Immunology (738 citations) and Oncology (538 citations). James R. Burke has collaborated with scholars based in United States, Germany and Australia. Frequent co-authors include Joann Strnad, Kurt R. Gregor, Mark A. Pattoli, Yuping Qiu, F. Christopher Zusi, Kim W. McIntyre, John F. MacMaster, Patrick Brassil, Wendy Clarke and Xiaoxia Yang. Their work appears in journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and Nature Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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