Wayne Vaccaro

1.7k citations

37 papers · 1.2k indexed · h-index 23

Impact in

Organic Chemistry top 5%
- Synthesis of β-Lactam Compounds
- Synthesis and Catalytic Reactions
- Asymmetric Synthesis and Catalysis
- Synthesis and biological activity
- Synthesis and Biological Evaluation
Molecular Biology
- Epigenetics and DNA Methylation
- Cancer-related gene regulation
- Chemical Synthesis and Analysis

Papers in

Cancer Research 11
- Synthesis and Biological Activity 4
Organic Chemistry 16
- Synthesis of β-Lactam Compounds 6
- Asymmetric Synthesis and Catalysis 3

Co-authors: Harry R. Davis Rosy Sher Michael A. Poss Tram Huynh Ashok V. Purandare Bret E. Huff Bruce H. Lipshutz John W. Clader
Journals: Bioorganic & Medicinal Chemistry Letters (21 papers)Journal of Medicinal Chemistry (7 papers)Tetrahedron Letters (4 papers)SLAS DISCOVERY (1 paper)Bioorganic & Medicinal Chemistry (1 paper)
Partner nations: United States Germany Japan

In The Last Decade

Wayne Vaccaro

37 papers receiving 1.1k citations

Peers

Countries citing papers authored by Wayne Vaccaro

Since Specialization

Citations

This map shows the geographic impact of Wayne Vaccaro's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wayne Vaccaro with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wayne Vaccaro more than expected).

Fields of papers citing papers by Wayne Vaccaro

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wayne Vaccaro. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wayne Vaccaro. The network helps show where Wayne Vaccaro may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Wayne Vaccaro, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Wayne Vaccaro Line = papers co-authored together Wayne Vaccaro links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)—Hit to Lead studies Bioorganic & Medicinal Chemistry Letters ·Honghe Wan, Tram Huynh, Suhong Pang, Jieping Geng, Wayne Vaccaro, Michael A. Poss, George L. Trainor, Matthew V. Lorenzi, Marco M. Gottardis, Lata Jayaraman, Ashok V. Purandare	2009	45
2	Discovery of novel dihydro-9,10-ethano-anthracene carboxamides as glucocorticoid receptor modulators Bioorganic & Medicinal Chemistry Letters ·Bingwei Yang, Wayne Vaccaro, Arthur M. Doweyko, P.B. Gibson, Tram Huynh, David R. Tortolani, Steven G. Nadler, Lorraine I. McKay, John E. Somerville, P.. Domia, E. SIEVERS, David S. Weinstein, Joel C. Barrish	2009	16
3	Dihydropyrazolopyrimidines containing benzimidazoles as KV1.5 potassium channel antagonists Bioorganic & Medicinal Chemistry Letters ·John Lloyd, Heather J. Finlay, Karnail S. Atwal, Zheng‐Fei Cai, Zarema Magomedovna Musayeva, Lin Yan, Sanda Bubanović, Wayne Vaccaro, Tram Huynh, Christine Huang, Vanessa Batista do. Nascimento, Tonya Jenkins-West, Huabin Sun, Danshi Li, Paul Lévesque	2009	35
4	Optimization of pyrazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1) Bioorganic & Medicinal Chemistry Letters ·Tram Huynh, Zhong Chen, Suhong Pang, Jieping Geng, Tiziano Bandiera, Simona Bindi, Paola Vianello, Fulvia Roletto, Sandrine Thieffine, Arturo Galvani, Wayne Vaccaro, Michael A. Poss, George L. Trainor, Matthew V. Lorenzi, Marco M. Gottardis, Lata Jayaraman, Ashok V. Purandare	2009	62
5	Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1) Bioorganic & Medicinal Chemistry Letters ·Ashok V. Purandare, Zhong Chen, Tram Huynh, Suhong Pang, Jieping Geng, Wayne Vaccaro, Michael A. Poss, Jonathan C. O’Connell, Kazi Sanjida Tahrim, Lata Jayaraman	2008	69
6	Dihydropyrazolopyrimidine Inhibitors of KV1.5 (IKur) Bioorganic & Medicinal Chemistry Letters ·Wayne Vaccaro, Tram Huynh, John Lloyd, Karnail S. Atwal, Heather J. Finlay, Paul Lévesque, Mary Lee Conder, Tonya Jenkins-West, Hong Shi, Lucy Sun	2008	24
7	Multiple and Single Binding Modes of Fragment-Like Kinase Inhibitors Revealed by Molecular Modeling, Residue Type-Selective Protonation, and Nuclear Overhauser Effects Journal of Medicinal Chemistry ·Keith L. Constantine, Luciano Mueller, William J. Metzler, Patricia A. McDonnell, Gordon Todderud, Valentina Goldfarb, Yi Fan, John A. Newitt, Susan E. Kiefer, Mian Gao, David R. Tortolani, Wayne Vaccaro, John S. Tokarski	2008	11
8	Benzopyran sulfonamides as KV1.5 potassium channel blockers Bioorganic & Medicinal Chemistry Letters ·John Lloyd, Karnail S. Atwal, Heather J. Finlay, 钱琦, Tram Huynh, Sanda Bubanović, Zheng‐Fei Cai, F.P.G. Potgens, Wayne Vaccaro, Mary Lee Conder, Tonya Jenkins-West, Paul Lévesque	2007	27
9	A Simple Strategy for Mitigating the Effect of Data Variability on the Identification of Active Chemotypes from High-Throughput Screening Data SLAS DISCOVERY ·Stephen R. Johnson, Ramesh Padmanabha, Wayne Vaccaro, Mark A. Hermsmeier, Angela Cacace, Robert Lawrence, J. ETTINGER, KalenahalliJagadish Kumar, Kristen Pike, Victoria Wong, Michaël Poss, Deborah A. Loughney, Andrew J. Tebben	2007	2
10	Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold Bioorganic & Medicinal Chemistry Letters ·Wayne Vaccaro, Rosy Sher, Michael Berlin, Neng‐Yang Shih, Robert Aslanian, Ye.N. Rosenvasser, Kevin D. McCormick, John J. Piwinski, Robert E. West, John C. Anthes, Shirley M. Williams, Renlong Wu, Hoyan S. She, Maria A. Rivelli, Carme Miranda, Michel R. Corboz, John A. Hey, Leonard Favreau	2005	4
11	Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13) Bioorganic & Medicinal Chemistry Letters ·Soong‐Hoon Kim, Andrew T. Pudzianowski, Kenneth J. Leavitt, Joseph Barbosa, Patricia A. McDonnell, William J. Metzler, Bruce Rankin, Richard Y. Liu, Wayne Vaccaro, William J. Pitts	2005	80
12	Pyrrolopyridazine MEK inhibitors Bioorganic & Medicinal Chemistry Letters ·Zhong Chen, Soong‐Hoon Kim, M. Myre, Tram Huynh, David R. Tortolani, Kenneth J. Leavitt, Donna Wei, Veeraswamy Manne, 陈子庆, Johnni Gullo-Brown, Michael A. Poss, Wayne Vaccaro, M. Greklek	2005	14
13	Identification of chemokine receptor CCR4 antagonist Bioorganic & Medicinal Chemistry Letters ·Ashok V. Purandare, 美広柳原, Honghe Wan, John E. Somerville, Christine Burke, Carrie L. Seachord, Wayne Vaccaro, John Wityak, Michael A. Poss	2005	54
14	Identification of a potent and rapidly reversible inhibitor of the 20S-proteasome Bioorganic & Medicinal Chemistry Letters ·Ashok V. Purandare, Honghe Wan, Naomi Laing, Khalid Benbatoul, Wayne Vaccaro, Michael A. Poss	2004	15
15	Identification of purine inhibitors of phosphodiesterase 7 (PDE7) Bioorganic & Medicinal Chemistry Letters ·William J. Pitts, Wayne Vaccaro, Tram Huynh, Katerina Leftheris, Jacques Y. Roberge, Joseph Barbosa, Junqing Guo, Gwamushi Gomari, Andrew J. Watson, Karen Donaldson, Gary C. Starling, Peter A. Kiener, Michael A. Poss, John H. Dodd, Joel C. Barrish	2004	38
16	Sugar-substituted 2-azetidinones as cholesterol absorption inhibitors Bioorganic & Medicinal Chemistry Letters ·Wayne Vaccaro, Rosy Sher, Harry R. Davis	1998	42
17	2-Azetidinone cholesterol absorption inhibitors: increased potency by substitution of the C-4 phenyl ring Bioorganic & Medicinal Chemistry ·Wayne Vaccaro, Rosy Sher, Harry R. Davis	1998	20
18	Sugar-substituted 2-azetidinone cholesterol absorption inhibitors: Enhanced potency by modification of the sugar Bioorganic & Medicinal Chemistry Letters ·Wayne Vaccaro, Harry R. Davis	1998	62
19	Carboxy-substituted 2-azetidinones as cholesterol absorption inhibitors Bioorganic & Medicinal Chemistry Letters ·Wayne Vaccaro, Rosy Sher, Harry R. Davis	1998	8
20	Substituted (1,2-Diarylethyl)amide Acyl-CoA:Cholesterol Acyltransferase Inhibitors: Effect of Polar Groups on in Vitro and in Vivo Activity Journal of Medicinal Chemistry ·John W. Clader, Joel G. Berger, Robert E. Burrier, Harry R. Davis, Martin S. Domalski, Sundeep Dugar, Timothy P. Kogan, Brian Salisbury, Wayne Vaccaro	1995	22

About Wayne Vaccaro

Wayne Vaccaro is a scholar working on Cancer Research, Organic Chemistry, Molecular Biology, Immunology and Cardiology and Cardiovascular Medicine, having authored 37 papers that have together received 1.2k indexed citations. Recurring topics across this work include Synthesis of β-Lactam Compounds (6 papers), Synthesis and Biological Activity (4 papers), Cardiac electrophysiology and arrhythmias (4 papers), Melanoma and MAPK Pathways (3 papers), Cholesterol and Lipid Metabolism (3 papers), Asymmetric Synthesis and Catalysis (3 papers), Cancer-related gene regulation (3 papers) and Epigenetics and DNA Methylation (3 papers). The work is most often cited by research in Organic Chemistry (648 citations), Molecular Biology (565 citations), Cancer Research (100 citations), Pharmaceutical Science (36 citations) and Oncology (144 citations). Wayne Vaccaro has collaborated with scholars based in United States, Germany and Japan. Frequent co-authors include Harry R. Davis, Rosy Sher, Michael A. Poss, Tram Huynh, Ashok V. Purandare, Bret E. Huff, Bruce H. Lipshutz, John W. Clader, Honghe Wan and Martin S. Domalski. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Tetrahedron Letters, SLAS DISCOVERY and Bioorganic & Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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