Alaric J. Dyckman

1.2k citations

21 papers · 612 indexed · h-index 12

Organic Chemistry top 5%
- Catalytic Alkyne Reactions 5
- Cyclopropane Reaction Mechanisms 5
- Synthesis and Catalytic Reactions 2
Pharmaceutical Science
Inorganic Chemistry
Molecular Biology
- Melanoma and MAPK Pathways 5
- Sphingolipid Metabolism and Signaling 4
Immunology
- interferon and immune responses 2
Computational Theory and Mathematics
- Computational Drug Discovery Methods 3
Oncology
- Cytokine Signaling Pathways and Interactions 3

Co-authors: Paul A. Wender Claudia M. Barzilay Craig O. Husfeld Marc J. C. Scanio Heiko Rieck Dieter Kadereit Jennifer A. Love Katerina Leftheris
Cited by: Organic Chemistry Pharmaceutical Science Inorganic Chemistry
Journals: Journal of the American Chemical Society (2 papers)Nature Communications (1 paper)Journal of Medicinal Chemistry (1 paper)
Partner nations: United States India Germany

In The Last Decade

Alaric J. Dyckman

21 papers receiving 599 citations

Peers

Countries citing papers authored by Alaric J. Dyckman

Since Specialization

Citations

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Fields of papers citing papers by Alaric J. Dyckman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alaric J. Dyckman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alaric J. Dyckman. The network helps show where Alaric J. Dyckman may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Alaric J. Dyckman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alaric J. Dyckman Line = papers co-authored together Alaric J. Dyckman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Orthosteric STING inhibition elucidates molecular correction of SAVI STING Nature Communications ·Tao Xie,Max Ruzanov,David Critton,Leidy Merselis,Joseph G. Naglich,John S. Sack,Ping Zhang,Chunshan Xie,Jeffrey Tredup,Laurel B. Stine,Cameron Messier,David L Hope,Janet Caceres‐Cortes,Luciano Mueller,Alaric J. Dyckman,John A. Newitt,Asmita Choudhury,Stephen C. Wilson	2025	2
2	AB0132 AFIMETORAN (BMS-986256), AN EQUIPOTENT TLR7/8 ANTAGONIST, DEMONSTRATES STEROID-SPARING EFFECTS IN A LUPUS MOUSE MODEL Annals of the Rheumatic Diseases ·Sujata Dudhgaonkar,Puneet Chopra,A Rudra,Suchitra Subramani,S. Palachandra,Nilesh Bhatt,V. Pabbala,Shatakshi Ranade,Durga Shiva Prasad Ega,Alaric J. Dyckman,Qihong Zhao	2023	2
3	Identification of 2-Pyridinylindole-Based Dual Antagonists of Toll-like Receptors 7 and 8 (TLR7/8) ACS Medicinal Chemistry Letters ·Ratna Kumar Sreekantha,Christopher P. Mussari,Dharmpal S. Dodd,Laxman Pasunoori,Subramanya Hegde,Shana Posy,David Critton,Stefan Ruepp,Murali Subramanian,Luisa Salter–Cid,Debarati M. Tagore,Sanket Sarodaya,Shailesh Dudhgaonkar,Michael A. Poss,Gary L. Schieven,Percy H. Carter,John E. Macor,Alaric J. Dyckman	2022	7
4	Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9) ACS Medicinal Chemistry Letters ·Christopher P. Mussari,Dharmpal S. Dodd,Ratna Kumar Sreekantha,Laxman Pasunoori,Honghe Wan,Shana Posy,David Critton,Stefan Ruepp,Murali Subramanian,Andrew J. Watson,Paul Davies,Gary L. Schieven,Luisa Salter–Cid,Ratika Srivastava,Debarati M. Tagore,Shailesh Dudhgaonkar,Michael A. Poss,Percy H. Carter,Alaric J. Dyckman	2020	30
5	Aryl Ether-Derived Sphingosine-1-Phosphate Receptor (S1P₁) Modulators: Optimization of the PK, PD, and Safety Profiles ACS Medicinal Chemistry Letters ·Zili Xiao,Michael G. Yang,T. G. Murali Dhar,Hai‐Yun Xiao,John L. Gilmore,David Marcoux,Kim W. McIntyre,Tracy L. Taylor,Hong Shi,Paul Lévesque,Anthony M. Marino,Georgia Cornelius,Arvind Mathur,Ding Ren Shen,Mary Ellen Cvijic,Lois D. Lehman‐McKeeman,Huadong Sun,Jenny Xie,Percy H. Carter,Alaric J. Dyckman	2020	4
6	Modulators of Sphingosine-1-phosphate Pathway Biology: Recent Advances of Sphingosine-1-phosphate Receptor 1 (S1P₁) Agonists and Future Perspectives Journal of Medicinal Chemistry ·Alaric J. Dyckman	2017	45
7	Regioselective Epoxide Ring Opening for the Stereospecific Scale-Up Synthesis of BMS-960, A Potent and Selective Isoxazole-Containing S1P₁ Receptor Agonist Organic Process Research & Development ·Xiaoping Hou,Huiping Zhang,Bang‐Chi Chen,Zhiwei Guo,Àmarjit Singh,Animesh Goswami,John L. Gilmore,James E. Sheppeck,Alaric J. Dyckman,Percy H. Carter,Arvind Mathur	2017	20
8	An Efficient Scale-Up Synthesis of BMS-520, a Potent and Selective Isoxazole-Containing S1P₁ Receptor Agonist Organic Process Research & Development ·Xiaoping Hou,Juliang Zhu,Bang‐Chi Chen,Scott H. Watterson,William J. Pitts,Alaric J. Dyckman,Percy H. Carter,Arvind Mathur,Huiping Zhang	2016	11
9	Integrating High-Content Analysis into a Multiplexed Screening Approach to Identify and Characterize GPCR Agonists SLAS DISCOVERY ·Ying‐Jie Zhu,John B. Watson,Mengjie Chen,Ding Ren Shen,Melissa Yarde,Michele Agler,Neil T. Burford,Andrew Alt,Sukhanya Jayachandra,Mary Ellen Cvijic,Litao Zhang,Alaric J. Dyckman,Jenny Xie,Jonathan C. O’Connell,Martyn Banks,Andrea D. Weston	2014	10
10	The identification of novel p38α isoform selective kinase inhibitors having an unprecedented p38α binding mode Bioorganic & Medicinal Chemistry Letters ·Stephen T. Wrobleski,Shuqun Lin,T. G. Murali Dhar,Alaric J. Dyckman,Tianle Li,Sidney Pitt,Rosemary Zhang,Yi Fan,Arthur M. Doweyko,John S. Tokarski,Kevin Kish,Susan E. Kiefer,John S. Sack,John A. Newitt,Mark R. Witmer,Murray McKinnon,Joel C. Barrish,John H. Dodd,Gary L. Schieven,Katerina Leftheris	2013	15
11	Development of a Practical Synthesis of a p38 Kinase Inhibitor via a Safe and Robust Amination Organic Process Research & Development ·Zhongping Shi,Susanne Kiau,Paul C. Lobben,John Hynes,Hong Wu,Luca Parlanti,Robert P. Discordia,Wendel W. Doubleday,Katerina Leftheris,Alaric J. Dyckman,Stephen T. Wrobleski,Konstantinos Dambalas,Srinivas Tummala,Simon Leung,Ehrlic Lo	2012	12
12	Discovery of pyrrolo[2,1-f][1,2,4]triazine C6-ketones as potent, orally active p38α MAP kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Alaric J. Dyckman,Tianle Li,Sidney Pitt,Rosemary Zhang,Ding Ren Shen,Kim W. McIntyre,Kathleen M. Gillooly,David J. Shuster,Arthur M. Doweyko,John S. Sack,Kevin Kish,Susan E. Kiefer,John A. Newitt,Hongjian Zhang,Punit H. Marathe,Murray McKinnon,Joel C. Barrish,John H. Dodd,Gary L. Schieven,Katerina Leftheris	2011	9
13	Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: Synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritis Bioorganic & Medicinal Chemistry Letters ·Alaric J. Dyckman,Charles M. Langevine,Claude Quesnelle,James Kempson,Junqing Guo,Patrice Gill,Steven H. Spergel,Scott H. Watterson,Tianle Li,David S. Nirschl,Kathleen M. Gillooly,Mark A. Pattoli,Kim W. McIntyre,Laishun Chen,Murray McKinnon,John H. Dodd,Joel C. Barrish,James R. Burke,William J. Pitts	2010	7
14	5-Amino-pyrazoles as potent and selective p38α inhibitors Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das,Robert V. Moquin,Alaric J. Dyckman,Tianle Li,Sidney Pitt,Rosemary Zhang,Ding Ren Shen,Kim W. McIntyre,Kathleen M. Gillooly,Arthur M. Doweyko,John A. Newitt,John S. Sack,Hongjian Zhang,Susan E. Kiefer,Kevin Kish,Murray McKinnon,Joel C. Barrish,John H. Dodd,Gary L. Schieven,Katerina Leftheris	2010	19
15	Synthesis, initial SAR and biological evaluation of 1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-amine derived inhibitors of IκB kinase Bioorganic & Medicinal Chemistry Letters ·James Kempson,Junqing Guo,Jagabandhu Das,Robert V. Moquin,Steven H. Spergel,Scott H. Watterson,Charles M. Langevine,Alaric J. Dyckman,Mark A. Pattoli,James R. Burke,Xiao-Xia Yang,Kathleen M. Gillooly,Kim W. McIntyre,Laishun Chen,John H. Dodd,Murray McKinnon,Joel C. Barrish,William J. Pitts	2009	16
16	N-Amination of Pyrrole and Indole Heterocycles with Monochloramine (NH₂Cl) The Journal of Organic Chemistry ·John Hynes,Wendel W. Doubleday,Alaric J. Dyckman,Jollie D. Godfrey,John A. Grosso,Susanne Kiau,Katerina Leftheris	2004	58
17	ChemInform Abstract: The First Intermolecular Transition Metal‐Catalyzed [5 + 2] Cycloadditions with Simple, Unactivated, Vinylcyclopropanes. ChemInform ·Paul A. Wender,Claudia M. Barzilay,Alaric J. Dyckman	2001	1
18	The First Intermolecular Transition Metal-Catalyzed [5+2] Cycloadditions with Simple, Unactivated, Vinylcyclopropanes Journal of the American Chemical Society ·Paul A. Wender,Claudia M. Barzilay,Alaric J. Dyckman	2000	136
19	A New and Practical Five-Carbon Component for Metal-Catalyzed [5 + 2] Cycloadditions: Preparative Scale Syntheses of Substituted Cycloheptenones Organic Letters ·Paul A. Wender,Alaric J. Dyckman,Craig O. Husfeld,Marc J. C. Scanio	2000	65
20	Transition Metal-Catalyzed [5 + 2] Cycloadditions of 2-Substituted-1-vinylcyclopropanes: Catalyst Control and Reversal of Regioselectivity Organic Letters ·Paul A. Wender,Alaric J. Dyckman	1999	63

About Alaric J. Dyckman

Alaric J. Dyckman is a scholar working on Organic Chemistry, Physiology and Computational Theory and Mathematics, having authored 21 papers that have together received 612 indexed citations. Recurring topics across this work include Catalytic Alkyne Reactions (5 papers), Melanoma and MAPK Pathways (5 papers), Cyclopropane Reaction Mechanisms (5 papers), Sphingolipid Metabolism and Signaling (4 papers), Computational Drug Discovery Methods (3 papers), Cytokine Signaling Pathways and Interactions (3 papers), interferon and immune responses (2 papers) and Synthesis and Catalytic Reactions (2 papers). The work is most often cited by research in Organic Chemistry (471 citations), Pharmaceutical Science (20 citations) and Inorganic Chemistry (43 citations). Alaric J. Dyckman has collaborated with scholars based in United States, India and Germany. Frequent co-authors include Paul A. Wender, Claudia M. Barzilay, Craig O. Husfeld, Marc J. C. Scanio, Heiko Rieck, Dieter Kadereit, Jennifer A. Love, Katerina Leftheris, Susanne Kiau and Wendel W. Doubleday. Their work appears in journals such as Journal of the American Chemical Society, Nature Communications and Journal of Medicinal Chemistry.

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