William J. Metzler

2.1k citations

45 papers · 1.4k indexed · h-index 22

Co-authors: Luciano Mueller Thomas Lavoie Mark S. Friedrichs Keith L. Constantine Bennett T. Farmer Aneka Bell Eileen Ernst Michael Wittekind
Topics: Protein Structure and Dynamics (12 papers)Enzyme Structure and Function (11 papers)RNA and protein synthesis mechanisms (4 papers)
Cited by: Immunology and Allergy Spectroscopy Molecular Biology
Journals: Journal of the American Chemical Society Journal of Biological Chemistry The Journal of Immunology
Partner nations: United States Germany Japan

In The Last Decade

William J. Metzler

45 papers receiving 1.3k citations

Peers

Countries citing papers authored by William J. Metzler

Since Specialization

Citations

This map shows the geographic impact of William J. Metzler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William J. Metzler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William J. Metzler more than expected).

Fields of papers citing papers by William J. Metzler

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William J. Metzler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William J. Metzler. The network helps show where William J. Metzler may publish in the future.

Co-authorship network of co-authors of William J. Metzler

This figure shows the co-authorship network connecting the top 25 collaborators of William J. Metzler. A scholar is included among the top collaborators of William J. Metzler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William J. Metzler. William J. Metzler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	An improved protocol for amino acid type-selective isotope labeling in insect cells 2017 ·Journal of Biomolecular NMR ·Yaqun Zhang,Hui Wei,Dianlin Xie,(unknown),(unknown),Mian Gao,Frank Marsilio,William J. Metzler,(unknown),Ping Zhang,Mark R. Witmer,Luciano Mueller,(unknown)	7
2	Building homogeneous time-resolved fluorescence resonance energy transfer assays for characterization of bivalent inhibitors of an inhibitor of apoptosis protein target 2015 ·Analytical Biochemistry ·Charu Chaudhry,Jonathan H. Davis,Yong Zhang,Shana Posy,Ming Lei,Henry Shen,Chunhong Yan,Brigitte Devaux,Litao Zhang,Yuval Blat,William J. Metzler,R. M. Borzilleri,Randy Talbott	3
3	Cloning, purification, crystallization and preliminary X-ray analysis of the catalytic domain of human receptor-like protein tyrosine phosphatase γ in three different crystal forms 2011 ·Acta Crystallographica Section F Structural Biology and Crystallization Communications ·Kevin Kish,Patricia A. McDonnell,Valentina Goldfarb,Mian Gao,William J. Metzler,David R. Langley,James W. Bryson,Susan E. Kiefer,Brian Carpenter,Walter A. Kostich,Ryan S. Westphal,S. Sheriff	2
4	Involvement of DPP‐IV catalytic residues in enzyme–saxagliptin complex formation 2008 ·Protein Science ·William J. Metzler,Joseph Yanchunas,Carolyn A. Weigelt,Kevin Kish,Herbert E. Klei,Dianlin Xie,Yaqun Zhang,Martin J. Corbett,James Tamura,Bin He,Lawrence G. Hamann,Mark Kirby,Jovita Marcinkeviciene	103
5	Multiple and Single Binding Modes of Fragment-Like Kinase Inhibitors Revealed by Molecular Modeling, Residue Type-Selective Protonation, and Nuclear Overhauser Effects 2008 ·Journal of Medicinal Chemistry ·Keith L. Constantine,Luciano Mueller,William J. Metzler,Patricia A. McDonnell,Gordon Todderud,Valentina Goldfarb,Yi Fan,John A. Newitt,Susan E. Kiefer,Mian Gao,David R. Tortolani,Wayne Vaccaro,John S. Tokarski	11
6	NMR Structure of a Potent Small Molecule Inhibitor Bound to Human Keratinocyte Fatty Acid-Binding Protein 2006 ·Journal of Medicinal Chemistry ·Patricia A. McDonnell,Keith L. Constantine,Valentina Goldfarb,Stephen R. Johnson,Richard Sulsky,David R. Magnin,Jeffrey A. Robl,Thomas J. Caulfield,Rex A. Parker,David S. Taylor,Leonard P. Adam,William J. Metzler,Luciano Mueller,Bennett T. Farmer	4
7	Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13) 2005 ·Bioorganic & Medicinal Chemistry Letters ·Soong‐Hoon Kim,Andrew T. Pudzianowski,Kenneth J. Leavitt,Joseph Barbosa,Patricia A. McDonnell,William J. Metzler,Bruce Rankin,Richard Y. Liu,Wayne Vaccaro,William J. Pitts	80
8	Mechanism of Gly-Pro-pNA cleavage catalyzed by dipeptidyl peptidase-IV and its inhibition by saxagliptin (BMS-477118) 2005 ·Archives of Biochemistry and Biophysics ·Young B. Kim,Lisa M. Kopcho,Mark Kirby,Lawrence G. Hamann,Carolyn A. Weigelt,William J. Metzler,Jovita Marcinkeviciene	62
9	Kinetic Studies on β-Site Amyloid Precursor Protein-cleaving Enzyme (BACE) 2003 ·Journal of Biological Chemistry ·(unknown),William J. Metzler,Mark R. Witmer,Robert A. Copeland,Jovita Marcinkeviciene	37
10	Characterization of the Three-Dimensional Solution Structure of Human Profilin: 1H, 13C, and 15N NMR Assignments amd Global Folding Pattern 2001 ·Europe PMC (PubMed Central) ·William J. Metzler,Keith L. Constantine,Mark S. Friedrichs,Aneka Bell,Eileen Ernst,Thomas Lavoie,Luciano Mueller	74
11	Analysis of the three-dimensional antigenic structure of giant ragweed allergen, Amb t 5 1998 ·Molecular Immunology ·Þórunn Rafnar,Mary Brummet,Donna Bassolino‐Klimas,William J. Metzler,David G. Marsh	12
12	Simulated annealing with restrained molecular dynamics using a flexible restraint potential: Theory and evaluation with simulated NMR constraints 1996 ·Protein Science ·Donna Bassolino‐Klimas,Roberto Tejero,Stanley R. Krystek,William J. Metzler,G.T. Montelione,Robert E. Bruccoleri	26
13	Refined solution structure of human profilin I 1995 ·Protein Science ·William J. Metzler,Bennett T. Farmer,Keith L. Constantine,Mark S. Friedrichs,Luciano Mueller,Thomas Lavoie	35
14	The Ligand Binding Domain of the Human Retinoic Acid Receptor γ Is Predominantly α-Helical with a Trp Residue in the Ligand Binding Site 1995 ·Journal of Biological Chemistry ·John A. Lupisella,(unknown),William J. Metzler,Peter R. Reczek	13
15	A Simple Method for Methionyl ϵ-Methyl 1H and 13C Chemical-Shift Identification in 13C-Labeled Proteins 1995 ·Journal of Magnetic Resonance Series B ·B.T Farmer,Thomas Lavoie,Luciano Mueller,William J. Metzler	1
16	Solution structure of the calcium channel antagonist ω‐conotoxin GVIA 1993 ·Protein Science ·Jack J. Skalicky,Daniel Cieśla,Arthur Pardi,William J. Metzler,(unknown)	34
17	Relaxation study of the backbone dynamics of human profilin by two‐dimensional ¹H‐¹⁵N NMR 1993 ·FEBS Letters ·Keith L. Constantine,Mark S. Friedrichs,Aneka Bell,Thomas Lavoie,Luciano Mueller,William J. Metzler	4
18	Characterization of the three-dimensional solution structure of human profilin: proton, carbon-13, and nitrogen-15 NMR assignments and global folding pattern 1993 ·Biochemistry ·William J. Metzler,Keith L. Constantine,Mark S. Friedrichs,Aneka Bell,Eileen Ernst,Thomas Lavoie,Luciano Mueller	113
19	Determining local conformational variations in DNA 1990 ·Journal of Molecular Biology ·William J. Metzler,(unknown),Douglas B. Kitchen,Ronald M. Levy,Arthur Pardi	63
20	Limited sampling of conformational space by the distance geometry algorithm: implications for structures generated from NMR data 1989 ·Biochemistry ·William J. Metzler,Dennis R. Hare,Arthur Pardi	54

About William J. Metzler

William J. Metzler is a scholar working on Immunology and Allergy, Biophysics and Spectroscopy, having authored 45 papers that have together received 1.4k indexed citations. Recurring topics across this work include Protein Structure and Dynamics (12 papers), Enzyme Structure and Function (11 papers) and RNA and protein synthesis mechanisms (4 papers). The work is most often cited by research in Immunology and Allergy (136 citations), Spectroscopy (217 citations) and Molecular Biology (900 citations). William J. Metzler has collaborated with scholars based in United States, Germany and Japan. Frequent co-authors include Luciano Mueller, Thomas Lavoie, Mark S. Friedrichs, Keith L. Constantine, Bennett T. Farmer, Aneka Bell, Eileen Ernst, Michael Wittekind, Jovita Marcinkeviciene and Ponzy Lu. Their work appears in journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and The Journal of Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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