Alejandro Aruffo

29.7k total citations · 11 hit papers
196 papers, 25.3k citations indexed

About

Alejandro Aruffo is a scholar working on Immunology, Molecular Biology and Immunology and Allergy. According to data from OpenAlex, Alejandro Aruffo has authored 196 papers receiving a total of 25.3k indexed citations (citations by other indexed papers that have themselves been cited), including 105 papers in Immunology, 94 papers in Molecular Biology and 71 papers in Immunology and Allergy. Recurrent topics in Alejandro Aruffo's work include Cell Adhesion Molecules Research (71 papers), Glycosylation and Glycoproteins Research (57 papers) and Monoclonal and Polyclonal Antibodies Research (57 papers). Alejandro Aruffo is often cited by papers focused on Cell Adhesion Molecules Research (71 papers), Glycosylation and Glycoproteins Research (57 papers) and Monoclonal and Polyclonal Antibodies Research (57 papers). Alejandro Aruffo collaborates with scholars based in United States, Germany and Japan. Alejandro Aruffo's co-authors include Ivan Stamenkovic, Brian Seed, J A Ledbetter, Diane Hollenbaugh, Randolph J. Noelle, Nitin K. Damle, Michael Melnick, Charles B. Underhill, Jeffrey A. Ledbetter and Jürgen Bajorath and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Alejandro Aruffo

194 papers receiving 24.5k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CD44 is the principal cell surface receptor for hyaluronate

1990 2.1k citations Alejandro Aruffo, Ivan Stamenkovic et al. profile →
Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

1996 1.2k citations Alejandro Aruffo, Diane Hollenbaugh et al. profile →
Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

1991 1.0k citations P S Linsley, William Brady et al. The Journal of Experimental Medicine profile →
Recognition by Elam-1 of the Sialyl-Le ^x Determinant on Myeloid and Tumor Cells

1990 846 citations Alejandro Aruffo, M P Bevilacqua et al. profile →
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

1997 727 citations Alejandro Aruffo, Jeffrey A. Ledbetter et al. profile →
A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells.

1992 698 citations R J Noelle, Michael Roy et al. profile →
The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

1993 663 citations Alejandro Aruffo, Diane Hollenbaugh et al. profile →
4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses

1997 649 citations Deryk Loo, Anthony W. Siadak et al. The Journal of Experimental Medicine profile →
IMMUNE REGULATION BY CD40 AND ITS LIGAND GP39

1996 539 citations Teresa M. Foy, Alejandro Aruffo et al. profile →
The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells.

1991 515 citations Ivan Stamenkovic, Alejandro Aruffo et al. profile →
Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils.

1996 503 citations Peter A. Kiener, J A Ledbetter et al. The Journal of Experimental Medicine profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Alejandro Aruffo	14.0k	8.3k	5.3k	4.3k	4.1k	196	25.3k
Nancy Hogg	11.3k 0.8×	7.2k 0.9×	7.2k 1.3×	1.8k 0.4×	2.4k 0.6×	200	21.0k
Dietmar Vestweber	9.2k 0.7×	13.9k 1.7×	8.8k 1.7×	4.4k 1.0×	4.5k 1.1×	323	30.1k
Steven T. Pals	6.2k 0.4×	9.6k 1.1×	2.4k 0.5×	3.1k 0.7×	5.0k 1.2×	238	20.9k
Ian Clark‐Lewis	14.7k 1.0×	9.9k 1.2×	3.6k 0.7×	1.5k 0.4×	12.0k 2.9×	202	29.6k
Ivan Stamenkovic	5.6k 0.4×	12.6k 1.5×	4.5k 0.8×	6.3k 1.5×	5.1k 1.3×	157	24.7k
Clifford A. Lowell	11.8k 0.8×	6.5k 0.8×	4.1k 0.8×	1.4k 0.3×	2.7k 0.7×	227	20.7k
Rodger P. McEver	9.6k 0.7×	9.5k 1.1×	11.7k 2.2×	3.4k 0.8×	3.0k 0.7×	183	27.6k
Minoru Fukuda	6.7k 0.5×	13.8k 1.7×	1.9k 0.3×	3.3k 0.8×	2.7k 0.7×	547	22.1k
Steven Μ. Albelda	13.6k 1.0×	10.6k 1.3×	5.7k 1.1×	2.0k 0.5×	13.2k 3.2×	315	35.5k
R. Alon	7.9k 0.6×	5.1k 0.6×	6.6k 1.2×	2.9k 0.7×	3.6k 0.9×	188	17.2k

Countries citing papers authored by Alejandro Aruffo

Since Specialization

Citations

This map shows the geographic impact of Alejandro Aruffo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alejandro Aruffo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alejandro Aruffo more than expected).

Fields of papers citing papers by Alejandro Aruffo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alejandro Aruffo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alejandro Aruffo. The network helps show where Alejandro Aruffo may publish in the future.

Co-authorship network of co-authors of Alejandro Aruffo

This figure shows the co-authorship network connecting the top 25 collaborators of Alejandro Aruffo. A scholar is included among the top collaborators of Alejandro Aruffo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alejandro Aruffo. Alejandro Aruffo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Salih, Helmut R., Gary C. Starling, Deryk Loo, et al.. (2000). Constitutive Expression of Functional 4-1BB (CD137) Ligand on Carcinoma Cells. The Journal of Immunology. 165(5). 2903–2910. 70 indexed citations

Termeer, Christian, Kelly L. Bennett, Johannes M. Weiss, et al.. (1999). Colocalization of basic fibroblast growth factor and CD44 isoforms containing the variably spliced exon v3 (CD44v3) in normal skin and in epidermal skin cancers. British Journal of Dermatology. 141(5). 824–832. 28 indexed citations

Ledbetter, J A, J A Francisco, Clay B. Siegall, et al.. (1997). Agonistic activity of a CD40-specific single-chain Fv constructed from the variable regions of mAb G28-5.. PubMed. 17(5-6). 427–35. 5 indexed citations

Starling, Gary C., Jürgen Bajorath, John Emswiler, et al.. (1997). Identification of Amino Acid Residues Important for Ligand Binding to Fas. The Journal of Experimental Medicine. 185(8). 1487–1492. 64 indexed citations

Guo, Yao, et al.. (1996). Identification of a costimulatory molecule rapidly induced by CD40L as CD44H.. The Journal of Experimental Medicine. 184(3). 955–961. 100 indexed citations

Patel, Dhavalkumar D., S. Wee, Leona P. Whichard, et al.. (1995). Identification and characterization of a 100-kD ligand for CD6 on human thymic epithelial cells.. The Journal of Experimental Medicine. 181(4). 1563–1568. 127 indexed citations

Kahn, Steven E., et al.. (1995). Trypanosoma cruzi amastigote adhesion to macrophages is facilitated by the mannose receptor.. The Journal of Experimental Medicine. 182(5). 1243–1258. 67 indexed citations

Foy, Teresa M., Dawne M. Page, Thomas J. Waldschmidt, et al.. (1995). An essential role for gp39, the ligand for CD40, in thymic selection.. The Journal of Experimental Medicine. 182(5). 1377–1388. 126 indexed citations

Maresh, Grace A., John Marken, Michael Neubauer, et al.. (1994). Cloning and Expression of the Gene for the Melanoma-Associated ME20 Antigen. DNA and Cell Biology. 13(2). 87–95. 22 indexed citations

10.

Bartolazzi, Armando, et al.. (1994). Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development.. The Journal of Experimental Medicine. 180(1). 53–66. 301 indexed citations

11.

Foy, Teresa M., Jon D. Laman, J A Ledbetter, et al.. (1994). gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory.. The Journal of Experimental Medicine. 180(1). 157–163. 358 indexed citations

12.

Foy, Teresa M., David M. Shepherd, Fiona H. Durie, et al.. (1993). In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.. The Journal of Experimental Medicine. 178(5). 1567–1575. 308 indexed citations

13.

Eertwegh, Alfons J. van den, Randolph J. Noelle, Michael Roy, et al.. (1993). In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions.. The Journal of Experimental Medicine. 178(5). 1555–1565. 218 indexed citations

14.

Nonoyama, Shigeaki, Diane Hollenbaugh, Alejandro Aruffo, J A Ledbetter, & HD Ochs. (1993). B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells.. The Journal of Experimental Medicine. 178(3). 1097–1102. 129 indexed citations

15.

Aruffo, Alejandro. (1992). Selectins: Adhesion Molecules with Multiple Carbohydrate Ligands.. Trends in Glycoscience and Glycotechnology. 4(16). 146–151. 9 indexed citations

16.

Liu, Yang, Barry Jones, Alejandro Aruffo, et al.. (1992). Heat-stable antigen is a costimulatory molecule for CD4 T cell growth.. The Journal of Experimental Medicine. 175(2). 437–445. 224 indexed citations

17.

Farr, Andrew G., et al.. (1992). Characterization and cloning of a novel glycoprotein expressed by stromal cells in T-dependent areas of peripheral lymphoid tissues.. The Journal of Experimental Medicine. 176(5). 1477–1482. 142 indexed citations

18.

Aruffo, Alejandro & Ivan Stamenkovic. (1991). The Hyaluronate Receptor (CD44).. Trends in Glycoscience and Glycotechnology. 3(13). 334–342. 3 indexed citations

19.

Linsley, P S, William Brady, Laura S. Grosmaire, et al.. (1991). Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.. The Journal of Experimental Medicine. 173(3). 721–730. 1003 indexed citations breakdown →

20.

Taichman, Darren B., Myron I. Cybulsky, Isabelle Djaffar, et al.. (1991). Tumor cell surface alpha 4 beta 1 integrin mediates adhesion to vascular endothelium: demonstration of an interaction with the N-terminal domains of INCAM-110/VCAM-1.. PubMed. 2(5). 347–355. 118 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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