Vanessa C. Wheeler

6.0k citations

54 papers · 3.6k indexed · h-index 27

Molecular Biology top 2%
Cellular and Molecular Neuroscience top 0.5%
Neurology top 1%
Genetics top 5%
Cell Biology top 10%

Co-authors: Marcy E. MacDonald Tammy Gillis James F. Gusella Richard H. Myers Audrey E. Hendricks Jayalakshmi Srinidhi Mysore Ella Dragileva Edith Lopez
Topics: Genetic Neurodegenerative Diseases (46 papers)Mitochondrial Function and Pathology (36 papers)Muscle Physiology and Disorders (11 papers)
Cited by: Cellular and Molecular Neuroscience Neurology Molecular Biology
Journals: Nucleic Acids Research Journal of Biological Chemistry Neuron
Partner nations: United States United Kingdom Germany

In The Last Decade

Vanessa C. Wheeler

54 papers receiving 3.6k citations

Peers

Countries citing papers authored by Vanessa C. Wheeler

Since Specialization

Citations

This map shows the geographic impact of Vanessa C. Wheeler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Vanessa C. Wheeler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Vanessa C. Wheeler more than expected).

Fields of papers citing papers by Vanessa C. Wheeler

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Vanessa C. Wheeler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Vanessa C. Wheeler. The network helps show where Vanessa C. Wheeler may publish in the future.

Co-authorship network of co-authors of Vanessa C. Wheeler

This figure shows the co-authorship network connecting the top 25 collaborators of Vanessa C. Wheeler. A scholar is included among the top collaborators of Vanessa C. Wheeler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Vanessa C. Wheeler. Vanessa C. Wheeler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington’s disease 2024 ·eLife ·(unknown),Jun Wan Shin,(unknown),Eun Pyo Hong,(unknown),Jacob M. Loupe,Vanessa C. Wheeler,(unknown),(unknown),Jong‐Min Lee	4
2	Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington’s disease 2023 ·eLife ·(unknown),Jun Wan Shin,(unknown),Eun Pyo Hong,(unknown),Jacob M. Loupe,Vanessa C. Wheeler,(unknown),(unknown),Jong‐Min Lee	6
3	CAG repeat expansion in the Huntington’s disease gene shapes linear and circular RNAs biogenesis 2023 ·PLoS Genetics ·(unknown),(unknown),(unknown),Takshashila Tripathi,Jessica Döring,Emanuela Kerschbamer,Francesca Di Leva,(unknown),(unknown),Marina Kovalenko,Jacopo Zasso,Luciano Conti,Vanessa C. Wheeler,Christoph Dieterich,Silvano Piazza,Erik Dassi,Marta Biagioli	13
4	Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via splice redirection 2021 ·Nucleic Acids Research ·Jennie C. L. Roy,Antonia Vitalo,(unknown),(unknown),Marina Kovalenko,(unknown),(unknown),Paula E. Cohen,Ed Grabczyk,Vanessa C. Wheeler,Ricardo Mouro Pinto	19
5	Special Issue: DNA Repair and Somatic Repeat Expansion in Huntington’s Disease 2021 ·Journal of Huntington s Disease ·Lesley Jones,Vanessa C. Wheeler,Christopher E. Pearson	4
6	Approaches to Sequence the HTT CAG Repeat Expansion and Quantify Repeat Length Variation 2021 ·Journal of Huntington s Disease ·Marc Ciosi,Sarah A. Cumming,Afroditi Chatzi,(unknown),William Tottey,(unknown),Graham Hamilton,Vanessa C. Wheeler,Ricardo Mouro Pinto,Seung Kwak,A. Jennifer Morton,Darren G. Monckton	18
7	Huntington’s Disease Pathogenesis: Two Sequential Components 2021 ·Journal of Huntington s Disease ·Eun Pyo Hong,Marcy E. MacDonald,Vanessa C. Wheeler,Lesley Jones,Peter Holmans,Michael Orth,Darren G. Monckton,Jeffrey D. Long,Seung Kwak,James F. Gusella,Jong‐Min Lee	54
8	Modifiers of CAG/CTG Repeat Instability: Insights from Mammalian Models 2021 ·Journal of Huntington s Disease ·Vanessa C. Wheeler,Vincent Dion	47
9	Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington’s disease knock-in mice is blocked by Mlh1 knock-out 2020 ·Human Molecular Genetics ·Jacob M. Loupe,Ricardo Mouro Pinto,Kyung‐Hee Kim,Tammy Gillis,Jayalakshmi Srinidhi Mysore,(unknown),Marina Kovalenko,Ryan Murtha,(unknown),James F. Gusella,Seung Kwak,David Howland,(unknown),Jong‐Min Lee,Vanessa C. Wheeler,Marcy E. MacDonald	50
10	Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice 2020 ·eLife ·Marina Kovalenko,Serkan Erdin,(unknown),Jason St. Claire,(unknown),Leroy Hubert,(unknown),Alexei Stortchevoi,Daniel M. Fass,Ricardo Mouro Pinto,Stephen J. Haggarty,John H. Wilson,Michael E. Talkowski,Vanessa C. Wheeler	8
11	HttQ111/+ Huntington’s Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction 2018 ·Journal of Huntington s Disease ·Marina Kovalenko,Austen J. Milnerwood,(unknown),Jason St. Claire,Jolene R. Guide,(unknown),Tammy Gillis,Ellen Sapp,Marian DiFiglia,Marcy E. MacDonald,Jeffrey B. Carroll,Jong‐Min Lee,Susan Tappan,Lynn A. Raymond,Vanessa C. Wheeler	25
12	Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport 2017 ·Neuron ·F. Gasset-Rosa,Carlos Chillón-Marinas,Alexander Goginashvili,Ranjit Singh Atwal,Jonathan W. Artates,Ricardos Tabet,Vanessa C. Wheeler,Anne G. Bang,Don W. Cleveland,Clotilde Lagier‐Tourenne	171
13	Differential effects of the Huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative 2011 ·Human Molecular Genetics ·Elisa Fossale,Ihn Sik Seong,Kathryn R. Coser,Toshi Shioda,Isaac S. Kohane,Vanessa C. Wheeler,James F. Gusella,Marcy E. MacDonald,Jong‐Min Lee	18
14	Stoichiometry of Base Excision Repair Proteins Correlates with Increased Somatic CAG Instability in Striatum over Cerebellum in Huntington's Disease Transgenic Mice 2009 ·PLoS Genetics ·(unknown),Brian R. Berquist,David M. Wilson,Vanessa C. Wheeler,Yvon Trottier,Karine Mérienne	109
15	Neocortical neurons cultured from mice with expanded cag repeats in the huntingtin gene: unaltered vulnerability to excitotoxins and other insults 2003 ·Neuroscience ·B. Joy Snider,Joel Moss,Fredy J. Revilla,(unknown),Vanessa C. Wheeler,Marcy E. MacDonald,Dennis W. Choi	24
16	Huntington's Disease 2003 ·NeuroMolecular Medicine ·Marcy E. MacDonald,Sílvia Ginés,James F. Gusella,Vanessa C. Wheeler	75
17	The HD Mutation Does Not Alter Neuronal Death in the Striatum of HdhQ92 Knock-in Mice after Mild Focal Ischemia 2002 ·Neurobiology of Disease ·Shobu Namura,Lorenz Hirt,Vanessa C. Wheeler,Kim McGinnis,(unknown),Michael A. Moskowitz,Marcy E. MacDonald,Francesca Persichetti	7
18	Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse 1999 ·Human Molecular Genetics ·Vanessa C. Wheeler	297
19	Synthesis of a modified gene encoding human ornithine transcarbamylase for expression in mammalian mitochondrial and universal translation systems: a novel approach towards correction of a genetic defect 1996 ·Gene ·Vanessa C. Wheeler,Chrisostomos Prodromou,Laurence H. Pearl,Robert Williamson,Charles Coutelle	15
20	Use of an operon fusion to induce expression and crystallisation of a Bacillus thuringiensis δ-endotoxin encoded by a cryptic gene 1994 ·Molecular and General Genetics MGG ·Neil Crickmore,Vanessa C. Wheeler,David J. Ellar	25

About Vanessa C. Wheeler

Vanessa C. Wheeler is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Neurology, having authored 54 papers that have together received 3.6k indexed citations. Recurring topics across this work include Genetic Neurodegenerative Diseases (46 papers), Mitochondrial Function and Pathology (36 papers) and Muscle Physiology and Disorders (11 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (2.7k citations), Neurology (923 citations) and Molecular Biology (3.1k citations). Vanessa C. Wheeler has collaborated with scholars based in United States, United Kingdom and Germany. Frequent co-authors include Marcy E. MacDonald, Tammy Gillis, James F. Gusella, Richard H. Myers, Audrey E. Hendricks, Jayalakshmi Srinidhi Mysore, Ella Dragileva, Edith Lopez, Jong‐Min Lee and Charles Coutelle. Their work appears in journals such as Nucleic Acids Research, Journal of Biological Chemistry and Neuron.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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