Chrisostomos Prodromou

16.7k citations

111 papers · 12.1k indexed · 4 hit papers · h-index 51

Molecular Biology top 0.2%
Materials Chemistry top 2%
Immunology top 1%
Computational Theory and Mathematics top 0.2%
Cell Biology top 0.5%

Co-authors: Laurence H. Pearl Peter W. Piper S. Mark Roe Barry Panaretou John E. Ladbury Ronan O’Brien Cara K. Vaughan Paul Workman
Topics: Heat shock proteins research (94 papers)Enzyme Structure and Function (36 papers)Protein Structure and Dynamics (33 papers)
Cited by: Aging Physical and Theoretical Chemistry Molecular Biology
Journals: Nature Cell Proceedings of the National Academy of Sciences
Partner nations: United Kingdom United States Germany

In The Last Decade

Chrisostomos Prodromou

111 papers receiving 11.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperone

1997 1.1k citations Chrisostomos Prodromou, S. Mark Roe et al. Cell profile →
Structure and Mechanism of the Hsp90 Molecular Chaperone Machinery

2006 879 citations Laurence H. Pearl, Chrisostomos Prodromou profile →
Structural Basis for Inhibition of the Hsp90 Molecular Chaperone by the Antitumor Antibiotics Radicicol and Geldanamycin

1999 823 citations S. Mark Roe, Chrisostomos Prodromou et al. profile →
Crystal structure of an Hsp90–nucleotide–p23/Sba1 closed chaperone complex

2006 758 citations S. Mark Roe, Cara K. Vaughan et al. profile →

Peers

Countries citing papers authored by Chrisostomos Prodromou

Since Specialization

Citations

This map shows the geographic impact of Chrisostomos Prodromou's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Chrisostomos Prodromou with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Chrisostomos Prodromou more than expected).

Fields of papers citing papers by Chrisostomos Prodromou

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Chrisostomos Prodromou. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Chrisostomos Prodromou. The network helps show where Chrisostomos Prodromou may publish in the future.

Co-authorship network of co-authors of Chrisostomos Prodromou

This figure shows the co-authorship network connecting the top 25 collaborators of Chrisostomos Prodromou. A scholar is included among the top collaborators of Chrisostomos Prodromou based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Chrisostomos Prodromou. Chrisostomos Prodromou is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The Crystal Structure of the Hsp90-LA1011 Complex and the Mechanism by Which LA1011 May Improve the Prognosis of Alzheimer’s Disease 2023 ·Biomolecules ·S. Mark Roe,Zsolt Török,Andrew McGown,Ibolya Horváth,John Spencer,(unknown),László Vı́gh,Chrisostomos Prodromou	7
2	Malachite Green Assay for the Discovery of Heat-Shock Protein 90 Inhibitors 2023 ·Journal of Visualized Experiments ·Sayan Dutta Gupta,Dae‐Geun Song,(unknown),Jae Wook Lee,Jin‐Soo Park,Chrisostomos Prodromou,Cheol‐Ho Pan	1
3	Two-colour single-molecule photoinduced electron transfer fluorescence imaging microscopy of chaperone dynamics 2021 ·Nature Communications ·(unknown),Andrea Schulze,Chrisostomos Prodromou,Hannes Neuweiler	24
4	Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone 2021 ·Cell Reports ·Mohinder Pal,Hugo Muñoz-Hernández,(unknown),Lihong Zhou,Gianluca Degliesposti,Mark Skehel,Emma L. Hesketh,Rebecca F. Thompson,Laurence H. Pearl,Óscar Llorca,Chrisostomos Prodromou	24
5	Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1 2019 ·Nature Communications ·Wanping Xu,Kristin Beebe,Juan D. Chavez,(unknown),Yinying Lu,Abbey D. Zuehlke,Dimitra Keramisanou,Jane B. Trepel,Chrisostomos Prodromou,Matthias P. Mayer,James E. Bruce,Ioannis Gelis,Len Neckers	47
6	In vivo bioassay to test the pathogenicity of missense human AIP variants 2018 ·Journal of Medical Genetics ·Elena Daniela Aflorei,Benjamin Klapholz,Chenghao Chen,Serban Radian,(unknown),(unknown),Chrisostomos Prodromou,Paulo S. Ribeiro,Ralf Stanewsky,Márta Korbonits	14
7	RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex 2018 ·Nature Communications ·Fabrizio Martino,Mohinder Pal,Hugo Muñoz-Hernández,(unknown),Rafael Núñez‐Ramírez,David Gil‐Carton,Gianluca Degliesposti,Mark Skehel,S. Mark Roe,Chrisostomos Prodromou,Laurence H. Pearl,Óscar Llorca	53
8	Dihydropyridines Allosterically Modulate Hsp90 Providing a Novel Mechanism for Heat Shock Protein Co-induction and Neuroprotection 2018 ·Frontiers in Molecular Biosciences ·S. Mark Roe,(unknown),Zsolt Török,Ibolya Horváth,László Vı́gh,Chrisostomos Prodromou	25
9	The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90 2017 ·PLoS ONE ·(unknown),Mohinder Pal,S. Mark Roe,Laurence H. Pearl,Chrisostomos Prodromou	28
10	Co-Crystalization and In Vitro Biological Characterization of 5-Aryl-4-(5-Substituted-2-4-Dihydroxyphenyl)-1,2,3-Thiadiazole Hsp90 Inhibitors 2012 ·PLoS ONE ·Swee Y. Sharp,S. Mark Roe,Egidijus Kazlauskas,Inga Čikotienė,Paul Workman,Daumantas Matulis,Chrisostomos Prodromou	18
11	Dynamic Tyrosine Phosphorylation Modulates Cycling of the HSP90-P50CDC37-AHA1 Chaperone Machine 2012 ·Molecular Cell ·Wanping Xu,Mehdi Mollapour,Chrisostomos Prodromou,(unknown),Bradley T. Scroggins,(unknown),Kristin Beebe,Marco Siderius,Min-Jung Lee,Anthony D. Couvillon,Jane B. Trepel,Yoshihiko Miyata,Robert L. Matts,Len Neckers	102
12	A simple yeast-based system for analyzing inhibitor resistance in the human cancer drug targets Hsp90α/β 2010 ·Biochemical Pharmacology ·Stefan H. Millson,Chrisostomos Prodromou,Peter W. Piper	19
13	Hsp90-Dependent Activation of Protein Kinases Is Regulated by Chaperone-Targeted Dephosphorylation of Cdc37 2008 ·Molecular Cell ·Cara K. Vaughan,Mehdi Mollapour,Jennifer R. Smith,Andrew W. Truman,Bin Hu,Valerie M. Good,Barry Panaretou,Len Neckers,Paul A. Clarke,Paul Workman,Peter W. Piper,Chrisostomos Prodromou,Laurence H. Pearl	166
14	Combinatorial Domain Hunting: An effective approach for the identification of soluble protein domains adaptable to high‐throughput applications 2006 ·Protein Science ·Stefanie Reich,L. Puckey,(unknown),Richard Harris,A. Ali,(unknown),Kate Maclagan,Keith A. Powell,Chrisostomos Prodromou,Laurence H. Pearl,Paul C. Driscoll,Renos Savva	28
15	Investigating the protein-protein interactions of the yeast Hsp90 chaperone system by two-hybrid analysis: potential uses and limitations of this approach 2004 ·Cell Stress and Chaperones ·Stefan H. Millson,Andrew W. Truman,(unknown),(unknown),Barry Panaretou,Chrisostomos Prodromou,Laurence H. Pearl,Peter W. Piper	39
16	Crystal structure and functional analysis of the middle segment of Hsp90: Implications for ATP hydrolysis and co-chaperone interactions. 2003 ·UCL Discovery (University College London) ·Philippe Meyer,Chrisostomos Prodromou,(unknown)	2
17	Activation of the ATPase Activity of Hsp90 by the Stress-Regulated Cochaperone Aha1 2002 ·Molecular Cell ·Barry Panaretou,Giuliano Siligardi,Philippe Meyer,Alison Maloney,(unknown),Shradha Singh,Stefan H. Millson,Paul A. Clarke,Søren Naaby‐Hansen,Robert C. Stein,Rainer Cramer,Mehdi Mollapour,Paul Workman,Peter W. Piper,Laurence H. Pearl,Chrisostomos Prodromou	415
18	Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones 1999 ·The EMBO Journal ·Chrisostomos Prodromou	352
19	Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperonebreakdown → 1997 ·Cell ·Chrisostomos Prodromou,S. Mark Roe,Ronan O’Brien,John E. Ladbury,Peter W. Piper,Laurence H. Pearl	1058
20	Synthesis of a modified gene encoding human ornithine transcarbamylase for expression in mammalian mitochondrial and universal translation systems: a novel approach towards correction of a genetic defect 1996 ·Gene ·Vanessa C. Wheeler,Chrisostomos Prodromou,Laurence H. Pearl,Robert Williamson,Charles Coutelle	15

About Chrisostomos Prodromou

Chrisostomos Prodromou is a scholar working on Physical and Theoretical Chemistry, Molecular Biology and Aging, having authored 111 papers that have together received 12.1k indexed citations. Recurring topics across this work include Heat shock proteins research (94 papers), Enzyme Structure and Function (36 papers) and Protein Structure and Dynamics (33 papers). The work is most often cited by research in Aging (312 citations), Physical and Theoretical Chemistry (1.4k citations) and Molecular Biology (11.0k citations). Chrisostomos Prodromou has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Laurence H. Pearl, Peter W. Piper, S. Mark Roe, Barry Panaretou, John E. Ladbury, Ronan O’Brien, Cara K. Vaughan, Paul Workman, Philippe Meyer and Maruf M. U. Ali. Their work appears in journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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