Christopher E. Pearson

11.3k total citations · 2 hit papers
110 papers, 7.3k citations indexed

About

Christopher E. Pearson is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Genetics. According to data from OpenAlex, Christopher E. Pearson has authored 110 papers receiving a total of 7.3k indexed citations (citations by other indexed papers that have themselves been cited), including 94 papers in Molecular Biology, 66 papers in Cellular and Molecular Neuroscience and 28 papers in Genetics. Recurrent topics in Christopher E. Pearson's work include Genetic Neurodegenerative Diseases (65 papers), DNA Repair Mechanisms (54 papers) and Mitochondrial Function and Pathology (33 papers). Christopher E. Pearson is often cited by papers focused on Genetic Neurodegenerative Diseases (65 papers), DNA Repair Mechanisms (54 papers) and Mitochondrial Function and Pathology (33 papers). Christopher E. Pearson collaborates with scholars based in Canada, United States and United Kingdom. Christopher E. Pearson's co-authors include John D. Cleary, Kerrie Nichol Edamura, Richard R. Sinden, Arturo López Castel, Kaalak Reddy, Bita Zamiri, Robert B. Macgregor, Gagan B. Panigrahi, Maria Zannis‐Hadjopoulos and Yuh‐Hwa Wang and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nucleic Acids Research and Journal of Biological Chemistry.

In The Last Decade

Christopher E. Pearson

109 papers receiving 7.2k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Repeat instability: mechanisms of dynamic mutations

2005 653 citations Christopher E. Pearson, Kerrie Nichol Edamura et al. profile →
Repeat instability : mechanisms of dynamic mutations

2005 604 citations Christopher E. Pearson profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Christopher E. Pearson	6.2k	3.6k	1.7k	793	433	110	7.3k
Maurice S. Swanson	12.5k 2.0×	4.4k 1.2×	887 0.5×	963 1.2×	784 1.8×	126	13.8k
Rashmi Kothary	5.1k 0.8×	1.1k 0.3×	1.1k 0.7×	512 0.6×	2.0k 4.7×	195	7.3k
Leeju C. Wu	4.9k 0.8×	453 0.1×	745 0.4×	924 1.2×	566 1.3×	20	6.2k
Włodzimierz J. Krzyżosiak	5.0k 0.8×	1.8k 0.5×	577 0.3×	357 0.5×	310 0.7×	121	5.8k
Laurent Schaeffer	4.5k 0.7×	623 0.2×	552 0.3×	521 0.7×	258 0.6×	105	5.5k
Alan Y. Sakaguchi	2.0k 0.3×	891 0.3×	915 0.6×	629 0.8×	101 0.2×	39	3.5k
Jon W. Gordon	3.0k 0.5×	670 0.2×	2.1k 1.3×	973 1.2×	572 1.3×	102	5.2k
Rik Gijsbers	3.1k 0.5×	395 0.1×	1.1k 0.7×	285 0.4×	231 0.5×	147	5.3k
Harald Jockusch	2.9k 0.5×	958 0.3×	281 0.2×	332 0.4×	479 1.1×	141	4.1k
Hong Joo Kim	5.5k 0.9×	551 0.2×	487 0.3×	1.6k 2.0×	968 2.2×	29	6.6k

Countries citing papers authored by Christopher E. Pearson

Since Specialization

Citations

This map shows the geographic impact of Christopher E. Pearson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher E. Pearson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher E. Pearson more than expected).

Fields of papers citing papers by Christopher E. Pearson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher E. Pearson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher E. Pearson. The network helps show where Christopher E. Pearson may publish in the future.

Co-authorship network of co-authors of Christopher E. Pearson

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher E. Pearson. A scholar is included among the top collaborators of Christopher E. Pearson based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher E. Pearson. Christopher E. Pearson is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Roos, Wynand P., Christopher E. Pearson, Sherry Leonard, et al.. (2025). DNA polymerase beta expression in head & neck cancer modulates the poly(ADP-ribose)-mediated replication checkpoint. DNA repair. 150. 103853–103853. 1 indexed citations

Sznajder, Łukasz J., Curtis A. Nutter, Katarzyna Taylor, et al.. (2025). Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes. Nature Neuroscience. 28(6). 1199–1212. 3 indexed citations

Schaake, Susen, Björn‐Hergen Laabs, Roland Dominic G. Jamora, et al.. (2024). Stability of Mosaic Divergent Repeat Interruptions in X‐Linked Dystonia‐Parkinsonism. Movement Disorders. 39(7). 1145–1153. 2 indexed citations

Mätlik, Kärt, Laura Kus, Amit Laxmikant Deshmukh, et al.. (2024). Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum. Nature Genetics. 56(3). 383–394. 49 indexed citations

Trinh, Joanne, Susen Schaake, Björn‐Hergen Laabs, et al.. (2022). Mosaic divergent repeat interruptions in XDP influence repeat stability and disease onset. Brain. 146(3). 1075–1082. 15 indexed citations

Mojarad, Bahareh A., Worrawat Engchuan, Brett Trost, et al.. (2022). Genome-wide tandem repeat expansions contribute to schizophrenia risk. Molecular Psychiatry. 27(9). 3692–3698. 22 indexed citations

Sadoway, Tara, Yue Yin, Quratulain Zulfiqar Ali, et al.. (2021). Genome sequencing identifies rare tandem repeat expansions and copy number variants in Lennox–Gastaut syndrome. Brain Communications. 3(3). fcab207–fcab207. 8 indexed citations

Deshmukh, Amit Laxmikant, Antônio Porro, Mohiuddin Mohiuddin, et al.. (2021). FAN1, a DNA Repair Nuclease, as a Modifier of Repeat Expansion Disorders. Journal of Huntington s Disease. 10(1). 95–122. 37 indexed citations

Jones, Lesley, Vanessa C. Wheeler, & Christopher E. Pearson. (2021). Special Issue: DNA Repair and Somatic Repeat Expansion in Huntington’s Disease. Journal of Huntington s Disease. 10(1). 3–5. 4 indexed citations

10.

Gall-Duncan, Terence, Nozomu Sato, Ryan K. C. Yuen, & Christopher E. Pearson. (2021). Advancing genomic technologies and clinical awareness accelerates discovery of disease-associated tandem repeat sequences. Genome Research. 32(1). 1–27. 37 indexed citations

11.

Zamiri, Bita, Mila Mirceta, Karol Bomsztyk, Robert B. Macgregor, & Christopher E. Pearson. (2015). Quadruplex formation by both G-rich and C-rich DNA strands of theC9orf72(GGGGCC)8•(GGCCCC)8 repeat: effect of CpG methylation. Nucleic Acids Research. 43(20). gkv1008–gkv1008. 63 indexed citations

12.

Reddy, Kaalak, et al.. (2014). Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability. Nucleic Acids Research. 42(16). 10473–10487. 81 indexed citations

13.

Tomé, Stéphanie, Jodie P. Simard, Randell T. Libby, et al.. (2013). Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age. Human Molecular Genetics. 23(6). 1606–1618. 41 indexed citations

14.

Axford, Michelle M., Yuh‐Hwa Wang, Masayuki Nakamori, et al.. (2013). Detection of Slipped-DNAs at the Trinucleotide Repeats of the Myotonic Dystrophy Type I Disease Locus in Patient Tissues. PLoS Genetics. 9(12). e1003866–e1003866. 48 indexed citations

15.

Tomé, Santiago, Gagan B. Panigrahi, Arturo López Castel, et al.. (2011). Maternal germline-specific effect of DNA ligase I on CTG/CAG instability. Human Molecular Genetics. 20(11). 2131–2143. 28 indexed citations

16.

Cleary, John D., Christopher E. Pearson, & Albert R. La Spada. (2006). 23 DNA Replication, Repeat Instability, and Human Disease. Cold Spring Harbor Monograph Archive. 47. 461–480. 1 indexed citations

17.

Edamura, Kerrie Nichol, et al.. (2005). Role of Replication and CpG Methylation in Fragile X Syndrome CGG Deletions in Primate Cells. The American Journal of Human Genetics. 76(2). 302–311. 39 indexed citations

18.

Matsuura, Tohru, Ping Fang, Christopher E. Pearson, et al.. (2005). Interruptions in the Expanded ATTCT Repeat of Spinocerebellar Ataxia Type 10: Repeat Purity as a Disease Modifier?. The American Journal of Human Genetics. 78(1). 125–129. 78 indexed citations

19.

Jin, Peng, Daniela C. Zarnescu, Fuping Zhang, et al.. (2003). RNA-Mediated Neurodegeneration Caused by the Fragile X Premutation rCGG Repeats in Drosophila. Neuron. 39(5). 739–747. 278 indexed citations

20.

Nichol, K. & Christopher E. Pearson. (2002). CpG Methylation Modifies the Genetic Stability of Cloned Repeat Sequences. Genome Research. 12(8). 1246–1256. 46 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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