Toshiro Sato

43.2k total citations · 16 hit papers
245 papers, 28.3k citations indexed

About

Toshiro Sato is a scholar working on Oncology, Molecular Biology and Genetics. According to data from OpenAlex, Toshiro Sato has authored 245 papers receiving a total of 28.3k indexed citations (citations by other indexed papers that have themselves been cited), including 63 papers in Oncology, 56 papers in Molecular Biology and 56 papers in Genetics. Recurrent topics in Toshiro Sato's work include Cancer Cells and Metastasis (51 papers), Digestive system and related health (34 papers) and Immune Cell Function and Interaction (18 papers). Toshiro Sato is often cited by papers focused on Cancer Cells and Metastasis (51 papers), Digestive system and related health (34 papers) and Immune Cell Function and Interaction (18 papers). Toshiro Sato collaborates with scholars based in Japan, United States and Netherlands. Toshiro Sato's co-authors include Hans Clevers, Johan H. van Es, Daniel E. Stange, Nick Barker, Marc van de Wetering, Hugo J.G. Snippert, Robert G.J. Vries, Arie Abo, Peter J. Peters and Pekka Kujala and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Toshiro Sato

232 papers receiving 27.9k citations

Hit Papers

Single Lgr5 stem cells build crypt-villus structures in v... 2009 2026 2014 2020 2009 2011 2010 2010 2010 1000 2.0k 3.0k 4.0k 5.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
    2009 5.1k citations Toshiro Sato, Hans Clevers et al. Nature profile →
  2. Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
    2011 2.6k citations Toshiro Sato, Hans Clevers et al. profile →
  3. Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
    2010 1.9k citations Toshiro Sato, Hans Clevers et al. Nature profile →
  4. Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells
    2010 1.4k citations Toshiro Sato, Hans Clevers et al. profile →
  5. Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro
    2010 1.2k citations Toshiro Sato, Hans Clevers et al. profile →
  6. In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
    2013 1.1k citations Toshiro Sato, Hans Clevers et al. Nature profile →
  7. Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications
    2013 870 citations Toshiro Sato, Hans Clevers profile →
  8. Modeling colorectal cancer using CRISPR-Cas9–mediated engineering of human intestinal organoids
    2015 848 citations Mami Matano, Masayuki Fujii et al. Nature Medicine profile →
  9. Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell
    2012 627 citations Shiro Yui, Tetsuya Nakamura et al. Nature Medicine profile →
  10. A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis
    2016 599 citations Masayuki Fujii, Mami Matano et al. profile →
  11. Dll1+ secretory progenitor cells revert to stem cells upon crypt damage
    2012 584 citations Toshiro Sato, Hans Clevers et al. Nature Cell Biology profile →
  12. Isolation and in vitro expansion of human colonic stem cells
    2011 550 citations Toshiro Sato, Hans Clevers et al. Nature Medicine profile →
  13. Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis
    2013 535 citations Toshiro Sato, Hans Clevers et al. profile →
  14. Visualization and targeting of LGR5+ human colon cancer stem cells
    2017 525 citations Yuki Ohta, Mami Matano et al. Nature profile →
  15. Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression
    2018 452 citations Kohta Toshimitsu, Masayuki Fujii et al. profile →
  16. Human Intestinal Organoids Maintain Self-Renewal Capacity and Cellular Diversity in Niche-Inspired Culture Condition
    2018 358 citations Masayuki Fujii, Mami Matano et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Toshiro Sato Japan 61 12.3k 12.1k 5.5k 5.3k 4.2k 245 28.3k
Nick Barker Singapore 62 15.2k 1.2× 23.9k 2.0× 6.9k 1.2× 3.5k 0.6× 4.5k 1.1× 119 38.8k
Peter J. Peters Netherlands 70 8.3k 0.7× 13.6k 1.1× 3.8k 0.7× 3.3k 0.6× 3.3k 0.8× 247 28.4k
Johan H. van Es Netherlands 72 17.7k 1.4× 23.1k 1.9× 8.0k 1.4× 4.5k 0.8× 5.8k 1.4× 131 41.4k
Pekka Kujala Netherlands 32 7.0k 0.6× 8.0k 0.7× 3.1k 0.6× 2.4k 0.4× 2.3k 0.6× 44 16.1k
Robert J. Coffey United States 98 7.8k 0.6× 16.7k 1.4× 3.3k 0.6× 1.0k 0.2× 5.9k 1.4× 416 34.1k
Steven Μ. Albelda United States 96 13.2k 1.1× 10.6k 0.9× 4.1k 0.7× 3.6k 0.7× 2.0k 0.5× 315 35.5k
Paul D. Robbins United States 105 5.6k 0.5× 18.6k 1.5× 7.1k 1.3× 1.9k 0.4× 5.6k 1.3× 530 38.1k
Klaus Ley United States 122 6.6k 0.5× 16.3k 1.3× 3.5k 0.6× 3.1k 0.6× 4.6k 1.1× 457 55.9k
Frédéric J. de Sauvage United States 86 8.0k 0.6× 17.7k 1.5× 4.7k 0.8× 947 0.2× 1.9k 0.5× 148 31.0k
Leonard D. Shultz United States 92 7.9k 0.6× 10.5k 0.9× 5.4k 1.0× 1.0k 0.2× 3.6k 0.9× 452 32.2k

Countries citing papers authored by Toshiro Sato

Since Specialization
Citations

This map shows the geographic impact of Toshiro Sato's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Toshiro Sato with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Toshiro Sato more than expected).

Fields of papers citing papers by Toshiro Sato

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Toshiro Sato. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Toshiro Sato. The network helps show where Toshiro Sato may publish in the future.

Co-authorship network of co-authors of Toshiro Sato

This figure shows the co-authorship network connecting the top 25 collaborators of Toshiro Sato. A scholar is included among the top collaborators of Toshiro Sato based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Toshiro Sato. Toshiro Sato is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Sonehara, Makoto, et al.. (2025). Ultra‐Minimally Invasive Current Measurement in Fast Switching GaN Devices Using Optical Probe Current Sensor. Electronics and Communications in Japan. 108(2).
2.
Sato, Toshiro, et al.. (2024). Organoids as regenerative medicine for inflammatory bowel disease. iScience. 27(6). 110118–110118. 9 indexed citations
3.
Hansen, Stine L., Lauge Kellermann, Svetlana Ulyanchenko, et al.. (2024). JAK/STAT signaling promotes the emergence of unique cell states in ulcerative colitis. Stem Cell Reports. 19(8). 1172–1188. 10 indexed citations
4.
Nagano, Yuji, Satoru Morita, Takeshi Tanoue, et al.. (2023). Diet-mediated constitutive induction of novel IL-4+ ILC2 cells maintains intestinal homeostasis in mice. The Journal of Experimental Medicine. 220(8). 14 indexed citations
5.
Okita, Yasutaka, Akinobu Matsumoto, Shoichiro Takeishi, et al.. (2022). Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium. Nature Communications. 13(1). 1500–1500. 30 indexed citations
6.
Sugimoto, Shinya, Eiji Kobayashi, Masayuki Fujii, et al.. (2021). An organoid-based organ-repurposing approach to treat short bowel syndrome. Nature. 592(7852). 99–104. 113 indexed citations
7.
Wang, Jingzhou, et al.. (2021). Covid-19 Reinfection: A Rapid Systematic Review of Case Reports and Case Series. Journal of Investigative Medicine. 69(6). 1253–1255. 76 indexed citations
8.
Pedersen, Marianne Terndrup, Yuki Ohta, Alberto Díez-Sánchez, et al.. (2020). LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium. Science Advances. 6(37). 21 indexed citations
9.
Sato, Taku, Jumpei Asano, Masayuki Fujii, et al.. (2020). Regulated IFN signalling preserves the stemness of intestinal stem cells by restricting differentiation into secretory-cell lineages. Nature Cell Biology. 22(8). 919–926. 25 indexed citations
10.
Yamashita, Takatoshi, et al.. (2018). Soyasapogenols reduce cellular triglyceride levels in 3T3-L1 mouse adipocyte cells by accelerating triglyceride lipolysis. Biochemistry and Biophysics Reports. 16. 44–49. 14 indexed citations
11.
Seishima, Ryo, T. Wada, Kenji Tsuchihashi, et al.. (2015). Ink4a/Arf -Dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-Dependent Gastric Tumorigenesis. Cancer Prevention Research. 8(6). 492–501. 14 indexed citations
12.
Oshima, Hiroko, Mizuho Nakayama, Tae-Su Han, et al.. (2015). Suppressing TGFβ Signaling in Regenerating Epithelia in an Inflammatory Microenvironment Is Sufficient to Cause Invasive Intestinal Cancer. Cancer Research. 75(4). 766–776. 78 indexed citations
13.
Nakaya, Takeo, Seishi Ogawa, Ichiro Manabe, et al.. (2014). KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells. Cancer Research. 74(10). 2882–2891. 57 indexed citations
14.
Hayashi, Atsushi, Toshiro Sato, Nobuhiko Kamada, et al.. (2013). A Single Strain of Clostridium butyricum Induces Intestinal IL-10-Producing Macrophages to Suppress Acute Experimental Colitis in Mice. Cell Host & Microbe. 13(6). 711–722. 258 indexed citations
15.
Yui, Shiro, Tetsuya Nakamura, Toshiro Sato, et al.. (2012). Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell. Nature Medicine. 18(4). 618–623. 627 indexed citations breakdown →
16.
Ikeda, Kenji, et al.. (2010). Double spiral inductors using CoFeSiO/SiO2 multilayer granular films with very narrow ferromagnetic resonance bandwidth. Journal of the Magnetics Society of Japan. 34(2). 123–130. 4 indexed citations
17.
Matsushita, Nobuhiro, Masanori Abe, Koichi Kondo, et al.. (2010). . Journal of The Surface Finishing Society of Japan. 61(6). 425–431. 1 indexed citations
18.
Kamada, Nobuhiko, Tadakazu Hisamatsu, Susumu Okamoto, et al.. (2005). Abnormally Differentiated Subsets of Intestinal Macrophage Play a Key Role in Th1-Dominant Chronic Colitis through Excess Production of IL-12 and IL-23 in Response to Bacteria. The Journal of Immunology. 175(10). 6900–6908. 187 indexed citations
19.
Sonehara, Makoto, et al.. (2004). FeSi/IrMn Exchange Coupled Multilayer Film with Plural FMR Absorption. SOAR (Shinshu University). 29(4). 1735–1738. 5 indexed citations
20.
Sato, Toshiro, et al.. (2001). FeCoBN Magnetic Thin Film Inductor for MHz Switching Micro DC-DC Converters. IEEJ Transactions on Industry Applications. 121(1). 84–89. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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