Hideyuki Saya

32.4k citations

458 papers · 23.7k indexed · 3 hit papers · h-index 81

Impact in

Cell Biology top 0.05%
- Microtubule and mitosis dynamics
- Proteoglycans and glycosaminoglycans research
Cancer Research top 0.1%
- Cancer, Hypoxia, and Metabolism

Papers in

Cell Biology 120
- Microtubule and mitosis dynamics 51
- Proteoglycans and glycosaminoglycans research 38
Oncology 181
- Cancer Cells and Metastasis 74
- Cancer-related Molecular Pathways 59

Co-authors: Osamu Nagano Tomotoshi Marumoto Dongwei Zhang Yoshimi Arima Toru Hirota Masayuki Nitta Eiji Sugihara Mitsuyoshi Nakao
Journals: Oncogene (29 papers)Cancer Science (27 papers)Cancer Research (26 papers)Journal of Biological Chemistry (18 papers)PLoS ONE (16 papers)
Partner nations: Japan United States Thailand

In The Last Decade

Hideyuki Saya

452 papers receiving 23.4k citations

Hit Papers

align trajectories log scale

Aurora-A — A guardian of poles 2005 · 584 citations

Peers

Countries citing papers authored by Hideyuki Saya

Since Specialization

Citations

This map shows the geographic impact of Hideyuki Saya's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hideyuki Saya with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hideyuki Saya more than expected).

Fields of papers citing papers by Hideyuki Saya

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hideyuki Saya. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hideyuki Saya. The network helps show where Hideyuki Saya may publish in the future.

Co-authors

The 25 scholars most cited alongside Hideyuki Saya, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hideyuki Saya Line = papers co-authored together Hideyuki Saya links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Benzaldehyde suppresses epithelial-mesenchymal plasticity and overcomes treatment resistance in cancer by targeting the interaction of 14-3-3ζ with H3S28ph British Journal of Cancer ·Jun Saito, Nobuyuki Onishi, Juntaro Yamasaki, Naoyoshi Koike, Yukie Hata, Kiyomi Kimura, Yuji Otsuki, Hiroyuki Nobusue, Oltea Sampetrean, Takatsune Shimizu, Shogo Okazaki, Eiji Sugihara, Hideyuki Saya	2025	4
2	TGFβ Signaling Activated by Cancer-Associated Fibroblasts Determines the Histological Signature of Lung Adenocarcinoma Cancer Research ·Ryo Sato, Kosuke Imamura, Takashi Semba, Yusuke Tomita, Sho Saeki, Koei Ikeda, Yoshihiro Komohara, Makoto Suzuki, Takuro Sakagami, Hideyuki Saya, Yoshimi Arima	2021	42
3	The Inhibitor of Apoptosis Protein Livin Confers Resistance to Fas-Mediated Immune Cytotoxicity in Refractory Lymphoma Cancer Research ·Eiji Sugihara, Norisato Hashimoto, Satoru Osuka, Takatsune Shimizu, Sayaka Ueno, Shogo Okazaki, Tomonori Yaguchi, Yutaka Kawakami, Kenjiro Kosaki, Taka-Aki Sato, Shinichiro Okamoto, Hideyuki Saya	2020	10
4	Identification of kit-ligand a as the Gene Responsible for the Medaka Pigment Cell Mutant few melanophore G3 Genes Genomes Genetics ·Yuji Otsuki, Yuki Okuda, Kiyoshi Naruse, Hideyuki Saya	2019	4
5	Myeloid Differentiation Factor 88 Signaling in Bone Marrow–Derived Cells Promotes Gastric Tumorigenesis by Generation of Inflammatory Microenvironment Cancer Prevention Research ·Yusuke Maeda, Kanae Echizen, Hiroko Oshima, Liang Yu, Natthiya Sakulsak, Osamu Hirose, Yoichi Yamada, Tadatsugu Taniguchi, Brendan J. Jenkins, Hideyuki Saya, Masanobu Oshima	2016	22
6	Simvastatin-Induced Apoptosis in Osteosarcoma Cells: A Key Role of RhoA-AMPK/p38 MAPK Signaling in Antitumor Activity Molecular Cancer Therapeutics ·Walied Kamel, Eiji Sugihara, Hiroyuki Nobusue, Sayaka Yamaguchi‐Iwai, Nobuyuki Onishi, Kenta Maki, Yumi Fukuchi, Koichi Matsuo, Akihiro Muto, Hideyuki Saya, Takatsune Shimizu	2016	78
7	MIF Maintains the Tumorigenic Capacity of Brain Tumor–Initiating Cells by Directly Inhibiting p53 Cancer Research ·Raita Fukaya, Shigeki Ohta, Tomonori Yaguchi, Yumi Matsuzaki, Eiji Sugihara, Hideyuki Okano, Hideyuki Saya, Yutaka Kawakami, Takeshi Kawase, Kazunari Yoshida, Masahiro Toda	2016	56
8	Ink4a/Arf -Dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-Dependent Gastric Tumorigenesis Cancer Prevention Research ·Ryo Seishima, T. Wada, Kenji Tsuchihashi, Shogo Okazaki, Momoko Yoshikawa, Hiroko Oshima, Masanobu Oshima, Toshiro Sato, Hirotoshi Hasegawa, Yuko Kitagawa, James R. Goldenring, Hideyuki Saya, Osamu Nagano	2015	14
9	Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases Molecular Cancer Therapeutics ·Kazuharu Kai, Kimie Kondo, Xiaoping Wang, Xuemei Xie, Mary Kathryn Pitner, Monica E. Reyes, Angie M. Torres-Adorno, Hiroko Masuda, Gabriel N. Hortobágyi, Chandra Bartholomeusz, Hideyuki Saya, Debu Tripathy, Subrata Sen, Naoto T. Ueno	2015	17
10	IGF2 Preserves Osteosarcoma Cell Survival by Creating an Autophagic State of Dormancy That Protects Cells against Chemotherapeutic Stress Cancer Research ·Takatsune Shimizu, Eiji Sugihara, Sayaka Yamaguchi‐Iwai, Sakura Tamaki, Yuko Koyama, Walied Kamel, Arisa Ueki, T. Ishikawa, Tatsuyuki Chiyoda, Satoru Osuka, Nobuyuki Onishi, Hiroko Ikeda, Junzo Kamei, Koichi Matsuo, Yumi Fukuchi, Toshihiro Nagai, Junya Toguchida, Yoshiaki Toyama, Akihiro Muto, Hideyuki Saya	2014	70
11	Energy Management by Enhanced Glycolysis in G1-phase in Human Colon Cancer Cells In Vitro and In Vivo Molecular Cancer Research ·Yan Bao, Kuniaki Mukai, Takako Hishiki, Akiko Kubo, Mitsuyo Ohmura, Yuki Sugiura, Tomomi Matsuura, Yoshiko Nagahata, Noriyo Hayakawa, Takehiro Yamamoto, Ryo Fukuda, Hideyuki Saya, Makoto Suematsu, Yoji Andrew Minamishima	2013	52
12	Acquired Expression of NFATc1 Downregulates E-Cadherin and Promotes Cancer Cell Invasion Cancer Research ·Tsukasa Oikawa, Atsuko Nakamura, Nobuyuki Onishi, Taketo Yamada, Koichi Matsuo, Hideyuki Saya	2013	26
13	xCT Inhibition Depletes CD44v-Expressing Tumor Cells That Are Resistant to EGFR-Targeted Therapy in Head and Neck Squamous Cell Carcinoma Cancer Research ·Momoko Yoshikawa, Kenji Tsuchihashi, Takatsugu Ishimoto, Toshifumi Yae, Takeshi Motohara, Eiji Sugihara, Nobuyuki Onishi, Takashi Masuko, Kunio Yoshizawa, Shuichi Kawashiri, Makio Mukai, Seiji Asoda, Hiromasa Kawana, Taneaki Nakagawa, Hideyuki Saya, Osamu Nagano	2013	168
14	CD44s Regulates the TGF-β–Mediated Mesenchymal Phenotype and Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma Cancer Research ·Kosuke Mima, Hirohisa Okabe, Takatsugu Ishimoto, Hiromitsu Hayashi, Shigeki Nakagawa, Hideyuki Kuroki, Masayuki Watanabe, Toru Beppu, Mayumi Tamada, Osamu Nagano, Hideyuki Saya, Hideo Baba	2012	181
15	Fibroblast Growth Factor-2 Is an Important Factor that Maintains Cellular Immaturity and Contributes to Aggressiveness of Osteosarcoma Molecular Cancer Research ·Takatsune Shimizu, T. Ishikawa, Sayaka Iwai, Arisa Ueki, Eiji Sugihara, Nobuyuki Onishi, Shinji Kuninaka, Takeshi Miyamoto, Yoshiaki Toyama, Hiroshi Ijiri, Hajime Mori, Yumi Matsuzaki, Tomonori Yaguchi, Hiroshi Nishio, Yutaka Kawakami, Yasuo Ikeda, Hideyuki Saya	2012	30
16	Modulation of Glucose Metabolism by CD44 Contributes to Antioxidant Status and Drug Resistance in Cancer Cells Cancer Research ·Mayumi Tamada, Osamu Nagano, Seiji Tateyama, Mitsuyo Ohmura, Toshifumi Yae, Takatsugu Ishimoto, Eiji Sugihara, Nobuyuki Onishi, Takehiro Yamamoto, Hiroshi Yanagawa, Makoto Suematsu, Hideyuki Saya	2012	213
17	PSF1, a DNA Replication Factor Expressed Widely in Stem and Progenitor Cells, Drives Tumorigenic and Metastatic Properties Cancer Research ·Yumi Nagahama, Masaya Ueno, S. Miyamoto, Eiichi Morii, Takashi Minami, Naoki Mochizuki, Hideyuki Saya, Nobuyuki Takakura	2010	57
18	NKX2.2 Suppresses Self-Renewal of Glioma-Initiating Cells Cancer Research ·Teruyuki Muraguchi, Shingo Tanaka, Daisuke Yamada, Akira Tamase, Mitsutoshi Nakada, Hideo Nakamura, Takayuki Hoshii, Takako Ooshio, Yuko Tadokoro, Kazuhito Naka, Yasushi Ino, Tomoki Todo, Jun‐ichi Kuratsu, Hideyuki Saya, Jun-ichiro Hamada, Atsushi Hirao	2010	21
19	M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis The Journal of Experimental Medicine ·Yoshiaki Kubota, Keiyo Takubo, Takatsune Shimizu, Hiroaki Ohno, Kazuo Kishi, Masabumi Shibuya, Hideyuki Saya, Toshio Suda	2009	317
20	Rb Depletion Results in Deregulation of E-Cadherin and Induction of Cellular Phenotypic Changes that Are Characteristic of the Epithelial-to-Mesenchymal Transition Cancer Research ·Yoshimi Arima, Yasumichi Inoue, Tatsuhiro Shibata, Hidemi Hayashi, Osamu Nagano, Hideyuki Saya, Yoichi Taya	2008	131

About Hideyuki Saya

Hideyuki Saya is a scholar working on Cell Biology, Oncology, Cancer Research, Molecular Biology and Genetics, having authored 458 papers that have together received 23.7k indexed citations. Recurring topics across this work include Cancer Cells and Metastasis (74 papers), Cancer-related Molecular Pathways (59 papers), Microtubule and mitosis dynamics (51 papers), Proteoglycans and glycosaminoglycans research (38 papers), Epigenetics and DNA Methylation (37 papers), Glioma Diagnosis and Treatment (32 papers), Cancer, Hypoxia, and Metabolism (30 papers) and Ubiquitin and proteasome pathways (23 papers). The work is most often cited by research in Cell Biology (6.6k citations), Cancer Research (4.4k citations), Oncology (7.2k citations), Molecular Biology (14.2k citations) and Immunology and Allergy (1.0k citations). Hideyuki Saya has collaborated with scholars based in Japan, United States and Thailand. Frequent co-authors include Osamu Nagano, Tomotoshi Marumoto, Dongwei Zhang, Yoshimi Arima, Toru Hirota, Masayuki Nitta, Eiji Sugihara, Mitsuyoshi Nakao, Go J. Yoshida and Takashi Sasayama. Their work appears in journals such as Oncogene, Cancer Science, Cancer Research, Journal of Biological Chemistry and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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