Makoto M. Taketo

52.0k total citations · 10 hit papers
392 papers, 39.1k citations indexed

About

Makoto M. Taketo is a scholar working on Molecular Biology, Genetics and Oncology. According to data from OpenAlex, Makoto M. Taketo has authored 392 papers receiving a total of 39.1k indexed citations (citations by other indexed papers that have themselves been cited), including 294 papers in Molecular Biology, 88 papers in Genetics and 60 papers in Oncology. Recurrent topics in Makoto M. Taketo's work include Wnt/β-catenin signaling in development and cancer (121 papers), Cancer-related gene regulation (64 papers) and Genetic factors in colorectal cancer (28 papers). Makoto M. Taketo is often cited by papers focused on Wnt/β-catenin signaling in development and cancer (121 papers), Cancer-related gene regulation (64 papers) and Genetic factors in colorectal cancer (28 papers). Makoto M. Taketo collaborates with scholars based in Japan, United States and Germany. Makoto M. Taketo's co-authors include Masanobu Oshima, Hiroko Oshima, Kazuaki Takaku, Walter Birchmeier, Hiroyuki Miyoshi, Koji Aoki, Stacia Kargman, Jilly F. Evans, Masahiro Sonoshita and James M. Trzăskos and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Makoto M. Taketo

389 papers receiving 38.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

1996 2.0k citations Masanobu Oshima, Hiroko Oshima et al. profile →
Canonical Wnt/β-Catenin Signaling Prevents Osteoblasts from Differentiating into Chondrocytes

2005 882 citations Makoto M. Taketo, Walter Birchmeier et al. profile →
Cyclooxygenase-2 Inhibitors in Tumorigenesis (Part I)

1998 671 citations Makoto M. Taketo profile →
Interactions between Sox9 and β-catenin control chondrocyte differentiation

2004 631 citations Makoto M. Taketo et al. profile →
Wnt/β-catenin signaling controls development of the blood–brain barrier

2008 622 citations Stefan Liebner, Marcus Fruttiger et al. The Journal of Cell Biology profile →
Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche

2011 575 citations Hiroyuki Miyoshi, Makoto M. Taketo et al. profile →
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene

2002 556 citations Makoto M. Taketo et al. profile →
TGF-β Receptor Type II Deficiency Results in Defects of Yolk Sac Hematopoiesis and Vasculogenesis

1996 540 citations Masanobu Oshima, Hiroko Oshima et al. Developmental Biology profile →
Wnt signalling induces maturation of Paneth cells in intestinal crypts

2005 518 citations Makoto M. Taketo et al. profile →
Acceleration of intestinal polyposis through prostaglandin receptor EP2 in ApcΔ716 knockout mice

2001 493 citations Masanobu Oshima, Makoto M. Taketo et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Makoto M. Taketo Japan	111	24.0k	7.9k	6.5k	4.6k	4.4k	392	39.1k
James R. Woodgett Canada	108	35.7k 1.5×	4.3k 0.5×	5.8k 0.9×	1.8k 0.4×	2.8k 0.6×	293	47.6k
Erwin F. Wagner Austria	115	33.7k 1.4×	5.7k 0.7×	14.2k 2.2×	1.6k 0.3×	2.9k 0.7×	364	50.7k
Keiji Tanaka Japan	112	37.9k 1.6×	3.7k 0.5×	7.5k 1.1×	2.1k 0.5×	2.4k 0.5×	428	55.1k
Shuh Narumiya Japan	125	28.8k 1.2×	6.5k 0.8×	6.0k 0.9×	14.4k 3.1×	3.6k 0.8×	556	60.6k
Marc Montminy United States	95	26.6k 1.1×	6.7k 0.9×	3.8k 0.6×	987 0.2×	6.9k 1.6×	162	39.9k
Toshio Suda Japan	120	32.9k 1.4×	4.1k 0.5×	17.0k 2.6×	2.0k 0.4×	4.2k 0.9×	730	59.1k
Nancy A. Jenkins United States	120	35.3k 1.5×	10.1k 1.3×	6.3k 1.0×	1.5k 0.3×	2.4k 0.6×	508	60.6k
Dario R. Alessi United Kingdom	124	50.6k 2.1×	2.8k 0.4×	7.7k 1.2×	1.7k 0.4×	6.2k 1.4×	313	65.6k
Chu‐Xia Deng United States	119	31.1k 1.3×	7.8k 1.0×	9.0k 1.4×	635 0.1×	3.0k 0.7×	414	47.2k
Hironobu Sasano Japan	87	11.1k 0.5×	8.7k 1.1×	8.2k 1.3×	934 0.2×	7.3k 1.7×	1.2k	36.3k

Countries citing papers authored by Makoto M. Taketo

Since Specialization

Citations

This map shows the geographic impact of Makoto M. Taketo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Makoto M. Taketo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Makoto M. Taketo more than expected).

Fields of papers citing papers by Makoto M. Taketo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Makoto M. Taketo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Makoto M. Taketo. The network helps show where Makoto M. Taketo may publish in the future.

Co-authorship network of co-authors of Makoto M. Taketo

This figure shows the co-authorship network connecting the top 25 collaborators of Makoto M. Taketo. A scholar is included among the top collaborators of Makoto M. Taketo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Makoto M. Taketo. Makoto M. Taketo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Macas, Jadranka, Eliza Wiercinska, Patrick N. Harter, et al.. (2023). Wnt/β-Catenin-Signaling Modulates Megakaryopoiesis at the Megakaryocyte-Erythrocyte Progenitor Stage in the Hematopoietic System. Cells. 12(23). 2765–2765. 4 indexed citations

Matsubara, Hiroyuki, Hiroyuki Miyoshi, Fumihiko Kakizaki, et al.. (2023). Efficacious Combination Drug Treatment for Colorectal Cancer That Overcomes Resistance to KRAS G12C Inhibitors. Molecular Cancer Therapeutics. 22(4). 529–538. 4 indexed citations

Li, Yu, Teruaki Fujishita, Emi Mishiro‐Sato, et al.. (2023). TGF‐β signaling promotes desmoid tumor formation via CSRP2 upregulation. Cancer Science. 115(2). 401–411. 3 indexed citations

Khodo, Stellor Nlandu, Marika Manolopoulou, Gautam Bhave, et al.. (2017). Blocking TGF-β and β-Catenin Epithelial Crosstalk Exacerbates CKD. Journal of the American Society of Nephrology. 28(12). 3490–3503. 48 indexed citations

Goto, Norihiro, Taro Ueo, Akihisa Fukuda, et al.. (2017). Distinct Roles of HES1 in Normal Stem Cells and Tumor Stem-like Cells of the Intestine. Cancer Research. 77(13). 3442–3454. 22 indexed citations

Yamamoto, Takamasa, Kenji Kawada, Yoshiro Itatani, et al.. (2016). Loss of SMAD4 Promotes Lung Metastasis of Colorectal Cancer by Accumulation of CCR1+ Tumor-Associated Neutrophils through CCL15-CCR1 Axis. Clinical Cancer Research. 23(3). 833–844. 75 indexed citations

Oshima, Hiroko, Mizuho Nakayama, Tae-Su Han, et al.. (2015). Suppressing TGFβ Signaling in Regenerating Epithelia in an Inflammatory Microenvironment Is Sufficient to Cause Invasive Intestinal Cancer. Cancer Research. 75(4). 766–776. 78 indexed citations

Inamoto, Susumu, Yoshiro Itatani, Takamasa Yamamoto, et al.. (2015). Loss of SMAD4 Promotes Colorectal Cancer Progression by Accumulation of Myeloid-Derived Suppressor Cells through the CCL15–CCR1 Chemokine Axis. Clinical Cancer Research. 22(2). 492–501. 106 indexed citations

Akiyama, Ryutaro, Hiroko Kawakami, Makoto M. Taketo, et al.. (2014). Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathway. Developmental Biology. 387(1). 37–48. 12 indexed citations

10.

Sakamori, Ryotaro, Shiyan Yu, Xiao Zhang, et al.. (2014). CDC42 Inhibition Suppresses Progression of Incipient Intestinal Tumors. Cancer Research. 74(19). 5480–5492. 44 indexed citations

11.

Gaston‐Massuet, Carles, Cynthia L. Andoniadou, Massimo Signore, et al.. (2011). Increased Wingless ( Wnt ) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans. Proceedings of the National Academy of Sciences. 108(28). 11482–11487. 204 indexed citations

12.

Chassot, Anne‐Amandine, Elodie P. Gregoire, Rowena Lavery, et al.. (2011). RSPO1/β-Catenin Signaling Pathway Regulates Oogonia Differentiation and Entry into Meiosis in the Mouse Fetal Ovary. PLoS ONE. 6(10). e25641–e25641. 101 indexed citations

13.

Hai, Bo, Zhenhua Yang, Sarah E. Millar, et al.. (2010). Wnt/β-Catenin Signaling Regulates Postnatal Development and Regeneration of the Salivary Gland. Stem Cells and Development. 19(11). 1793–1801. 73 indexed citations

14.

Oshima, Hiroko, Hiraku Itadani, Hidehito Kotani, Makoto M. Taketo, & Masanobu Oshima. (2009). Induction of Prostaglandin E2 Pathway Promotes Gastric Hamartoma Development with Suppression of Bone Morphogenetic Protein Signaling. Cancer Research. 69(7). 2729–2733. 25 indexed citations

15.

Dunty, William C., Kristin K. Biris, Ravindra B. Chalamalasetty, et al.. (2007). Wnt3a/β-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development. 135(1). 85–94. 164 indexed citations

16.

Klaus‐Bergmann, Alexandra, Yumiko Saga, Makoto M. Taketo, Eldad Tzahor, & Walter Birchmeier. (2007). Distinct roles of Wnt/β-catenin and Bmp signaling during early cardiogenesis. Proceedings of the National Academy of Sciences. 104(47). 18531–18536. 213 indexed citations

17.

Zechner, Dietmar, Thomas Müller, Hagen Wende, et al.. (2006). Bmp and Wnt/β-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons. Developmental Biology. 303(1). 181–190. 76 indexed citations

18.

Ohyama, Takahiro, Othman A. Mohamed, Makoto M. Taketo, Daniel Dufort, & Andrew K. Groves. (2006). Wnt signals mediate a fate decision between otic placode and epidermis. Development. 133(5). 865–875. 193 indexed citations

19.

Shimizu, Yoshihiko, Dean Thumkeo, Toshimasa Ishizaki, et al.. (2005). ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles. The Journal of Cell Biology. 168(6). 941–953. 258 indexed citations

20.

Brault, Véronique, et al.. (2004). Instructive Role of Wnt/ß-Catenin in Sensory Fate Specification in Neural Crest Stem Cells. Science. 303(5660). 1020–1023. 336 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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