Akihiko Yoshimura

27.9k total citations · 9 hit papers
191 papers, 22.8k citations indexed

About

Akihiko Yoshimura is a scholar working on Oncology, Immunology and Molecular Biology. According to data from OpenAlex, Akihiko Yoshimura has authored 191 papers receiving a total of 22.8k indexed citations (citations by other indexed papers that have themselves been cited), including 147 papers in Oncology, 94 papers in Immunology and 53 papers in Molecular Biology. Recurrent topics in Akihiko Yoshimura's work include Cytokine Signaling Pathways and Interactions (135 papers), interferon and immune responses (42 papers) and Pharmacological Effects of Natural Compounds (24 papers). Akihiko Yoshimura is often cited by papers focused on Cytokine Signaling Pathways and Interactions (135 papers), interferon and immune responses (42 papers) and Pharmacological Effects of Natural Compounds (24 papers). Akihiko Yoshimura collaborates with scholars based in Japan, United States and Canada. Akihiko Yoshimura's co-authors include Toshikatsu Hanada, Hideo Yasukawa, Tetsuji Naka, Masato Kubo, Atsuo T. Sasaki, Masato Kubo, Ichiko Kinjyo, Akira Matsumoto, Hiroyuki Mori and Masaaki Masuhara and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Akihiko Yoshimura

190 papers receiving 22.4k citations

Hit Papers

SOCS proteins, cytokine s... 1997 2026 2006 2016 2007 1997 2003 2002 2002 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. SOCS proteins, cytokine signalling and immune regulation
    2007 1.3k citations Akihiko Yoshimura et al. profile →
  2. A new protein containing an SH2 domain that inhibits JAK kinases
    1997 1.2k citations Akihiko Yoshimura et al. profile →
  3. IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
    2003 647 citations Hideo Yasukawa, Toshikatsu Hanada et al. profile →
  4. Regulation of cytokine signaling and inflammation
    2002 612 citations Akihiko Yoshimura et al. profile →
  5. SOCS1/JAB Is a Negative Regulator of LPS-Induced Macrophage Activation
    2002 540 citations Ichiko Kinjyo, Toshikatsu Hanada et al. profile →
  6. Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells
    2006 539 citations Yuka Kanno, Akihiko Yoshimura et al. profile →
  7. Suppressors of cytokine signaling and immunity
    2003 538 citations Masato Kubo, Toshikatsu Hanada et al. profile →
  8. Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
    2004 517 citations Toshikatsu Hanada, Takehiro Torisu et al. profile →
  9. Negative Regulation of Cytokine Signaling Pathways
    2000 513 citations Hideo Yasukawa, Akihiko Yoshimura et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Akihiko Yoshimura Japan 79 11.2k 11.0k 7.1k 2.7k 2.4k 191 22.8k
Douglas J. Hilton Australia 82 12.4k 1.1× 10.7k 1.0× 10.3k 1.5× 2.4k 0.9× 2.3k 0.9× 218 25.5k
Warren S. Alexander Australia 71 9.1k 0.8× 8.8k 0.8× 9.1k 1.3× 2.1k 0.8× 1.6k 0.7× 228 21.7k
Peter C. Heinrich Germany 75 11.9k 1.1× 9.6k 0.9× 9.4k 1.3× 3.1k 1.2× 1.9k 0.8× 368 27.7k
Nicos A. Nicola Australia 88 12.2k 1.1× 13.4k 1.2× 10.5k 1.5× 2.1k 0.8× 1.9k 0.8× 333 29.2k
Donald Metcalf Australia 89 8.7k 0.8× 13.6k 1.2× 12.5k 1.8× 2.2k 0.8× 1.2k 0.5× 305 30.6k
Akihiko Yoshimura Japan 82 7.0k 0.6× 11.3k 1.0× 10.6k 1.5× 3.1k 1.1× 575 0.2× 349 27.4k
Sergei I. Grivennikov United States 47 10.0k 0.9× 8.6k 0.8× 8.2k 1.2× 4.7k 1.8× 612 0.3× 73 24.3k
James N. Ihle United States 100 16.8k 1.5× 17.9k 1.6× 14.4k 2.0× 3.7k 1.4× 2.4k 1.0× 286 37.5k
Gennaro Ciliberto Italy 73 7.2k 0.6× 5.9k 0.5× 9.5k 1.3× 2.7k 1.0× 646 0.3× 435 22.3k
Valeria Poli Italy 66 5.1k 0.5× 5.0k 0.5× 6.1k 0.9× 2.1k 0.8× 597 0.2× 148 16.0k

Countries citing papers authored by Akihiko Yoshimura

Since Specialization
Citations

This map shows the geographic impact of Akihiko Yoshimura's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Akihiko Yoshimura with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Akihiko Yoshimura more than expected).

Fields of papers citing papers by Akihiko Yoshimura

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Akihiko Yoshimura. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Akihiko Yoshimura. The network helps show where Akihiko Yoshimura may publish in the future.

Co-authorship network of co-authors of Akihiko Yoshimura

This figure shows the co-authorship network connecting the top 25 collaborators of Akihiko Yoshimura. A scholar is included among the top collaborators of Akihiko Yoshimura based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Akihiko Yoshimura. Akihiko Yoshimura is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Khan, Md Gulam Musawwir, Nadia Boufaied, Mehdi Yeganeh, et al.. (2023). SOCS1 Deficiency Promotes Hepatocellular Carcinoma via SOCS3-Dependent CDKN1A Induction and NRF2 Activation. Cancers. 15(3). 905–905. 12 indexed citations
2.
Takahashi, Hayato, Hiroyuki Nomura, Akiko Kubo, et al.. (2021). Cholesterol 25-hydroxylase is a metabolic switch to constrain T cell–mediated inflammation in the skin. Science Immunology. 6(64). eabb6444–eabb6444. 15 indexed citations
3.
Nakamura, Koji, Kenjiro Sawada, Yasuto Kinose, et al.. (2016). Exosomes Promote Ovarian Cancer Cell Invasion through Transfer of CD44 to Peritoneal Mesothelial Cells. Molecular Cancer Research. 15(1). 78–92. 183 indexed citations
4.
Tando, Toshimi, Akiyoshi Hirayama, Mitsuru Furukawa, et al.. (2016). Smad2/3 Proteins Are Required for Immobilization-induced Skeletal Muscle Atrophy. Journal of Biological Chemistry. 291(23). 12184–12194. 48 indexed citations
5.
Miyahara, Nobuaki, Akihiko Taniguchi, Koichi Waseda, et al.. (2016). IL-23 Is Essential for the Development of Elastase-Induced Pulmonary Inflammation and Emphysema. American Journal of Respiratory Cell and Molecular Biology. 55(5). 697–707. 29 indexed citations
6.
Hayashi, Atsushi, Toshiro Sato, Nobuhiko Kamada, et al.. (2013). A Single Strain of Clostridium butyricum Induces Intestinal IL-10-Producing Macrophages to Suppress Acute Experimental Colitis in Mice. Cell Host & Microbe. 13(6). 711–722. 258 indexed citations
7.
Kawano, Yoshinaga, Jun Nakae, Nobuyuki Watanabe, et al.. (2012). Loss of Pdk1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance. Diabetes. 61(8). 1935–1948. 53 indexed citations
8.
Nakaya, Mako, Masayuki Hashimoto, Ryusuke Nakagawa, et al.. (2009). SOCS3 in T and NKT Cells Negatively Regulates Cytokine Production and Ameliorates ConA-Induced Hepatitis. The Journal of Immunology. 183(11). 7047–7053. 37 indexed citations
9.
Miyamoto, Kana, Takeshi Miyamoto, Reiko Kato, et al.. (2008). FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging. Blood. 112(12). 4485–4493. 66 indexed citations
10.
Tanaka, Kentaro, Kenji Ichiyama, Masayuki Hashimoto, et al.. (2008). Loss of Suppressor of Cytokine Signaling 1 in Helper T Cells Leads to Defective Th17 Differentiation by Enhancing Antagonistic Effects of IFN-γ on STAT3 and Smads. The Journal of Immunology. 180(6). 3746–3756. 154 indexed citations
11.
Kinjyo, Ichiko, Hiromasa Inoue, Shinjiro Hamano, et al.. (2006). Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor–β1. The Journal of Experimental Medicine. 203(4). 1021–1031. 196 indexed citations
12.
Tokumaru, Sho, Koji Sayama, Yuji Shirakata, et al.. (2005). Induction of Keratinocyte Migration via Transactivation of the Epidermal Growth Factor Receptor by the Antimicrobial Peptide LL-37. The Journal of Immunology. 175(7). 4662–4668. 284 indexed citations
13.
Ming‐Lum, Andrew, Christopher J. Ong, Michael Cox, et al.. (2005). Divergent Mechanisms Utilized by SOCS3 to Mediate Interleukin-10 Inhibition of Tumor Necrosis Factor α and Nitric Oxide Production by Macrophages. Journal of Biological Chemistry. 281(10). 6316–6324. 82 indexed citations
14.
Takatori, Hiroaki, Hiroshi Nakajima, Koichi Hirose, et al.. (2005). Stat5a Inhibits IL-12-Induced Th1 Cell Differentiation through the Induction of Suppressor of Cytokine Signaling 3 Expression. The Journal of Immunology. 174(7). 4105–4112. 47 indexed citations
15.
Miyazaki, Yoshiyuki, Hiroshi Inoue, Mikiko Matsumura, et al.. (2005). Exacerbation of Experimental Allergic Asthma by Augmented Th2 Responses in WSX-1-Deficient Mice. The Journal of Immunology. 175(4). 2401–2407. 100 indexed citations
16.
Takeda, Atsunobu, Shinjiro Hamano, Atsushi Yamanaka, et al.. (2003). Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment. The Journal of Immunology. 170(10). 4886–4890. 458 indexed citations
17.
Cohen, Yaël, et al.. (2002). Recombinant human CIS2 (SOCS2) protein: subcloning, expression, purification, and characterization. Protein Expression and Purification. 25(2). 305–312. 1 indexed citations
18.
Berlato, Chiara, et al.. (2002). Involvement of Suppressor of Cytokine Signaling-3 as a Mediator of the Inhibitory Effects of IL-10 on Lipopolysaccharide-Induced Macrophage Activation. The Journal of Immunology. 168(12). 6404–6411. 229 indexed citations
19.
Yoshida, Takafumi, Toshikatsu Hanada, Toru Wakioka, et al.. (2001). Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis. Journal of Clinical Investigation. 108(12). 1781–1788. 331 indexed citations
20.
Cohney, S., Nicholas A. Cacalano, Akihiko Yoshimura, et al.. (1999). SOCS-3 Is Tyrosine Phosphorylated in Response to Interleukin-2 and Suppresses STAT5 Phosphorylation and Lymphocyte Proliferation. Molecular and Cellular Biology. 19(7). 4980–4988. 213 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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