C.H. Arrowsmith

42.8k total citations · 7 hit papers
363 papers, 23.7k citations indexed

About

C.H. Arrowsmith is a scholar working on Molecular Biology, Materials Chemistry and Oncology. According to data from OpenAlex, C.H. Arrowsmith has authored 363 papers receiving a total of 23.7k indexed citations (citations by other indexed papers that have themselves been cited), including 326 papers in Molecular Biology, 74 papers in Materials Chemistry and 55 papers in Oncology. Recurrent topics in C.H. Arrowsmith's work include Epigenetics and DNA Methylation (91 papers), Protein Structure and Dynamics (82 papers) and Cancer-related gene regulation (76 papers). C.H. Arrowsmith is often cited by papers focused on Epigenetics and DNA Methylation (91 papers), Protein Structure and Dynamics (82 papers) and Cancer-related gene regulation (76 papers). C.H. Arrowsmith collaborates with scholars based in Canada, United States and United Kingdom. C.H. Arrowsmith's co-authors include Matthieu Schapira, A.M. Edwards, Masoud Vedadi, Dalia Baršytė-Lovejoy, C. Bountra, Kevin Lee, Paul V. Fish, Alexander Lemak, Shili Duan and Weontae Lee and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

C.H. Arrowsmith

355 papers receiving 23.3k citations

Hit Papers

Histone Recognition and Large-Scale Structural Analysis o... 2008 2026 2014 2020 2012 2012 2008 2017 2021 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
    2012 1.2k citations Dalia Baršytė-Lovejoy, C.H. Arrowsmith et al. profile →
  2. Epigenetic protein families: a new frontier for drug discovery
    2012 1.0k citations C.H. Arrowsmith, Matthieu Schapira et al. profile →
  3. Consistent blind protein structure generation from NMR chemical shift data
    2008 669 citations Yang Shen, Oliver F. Lange et al. Proceedings of the National Academy of Sciences profile →
  4. Global analysis of protein folding using massively parallel design, synthesis, and testing
    2017 305 citations Sugyan M. Dixit, Tamuka M. Chidyausiku et al. Science profile →
  5. Protein arginine methylation: from enigmatic functions to therapeutic targeting
    2021 274 citations Matthieu Schapira, C.H. Arrowsmith et al. profile →
  6. MYC protein interactors in gene transcription and cancer
    2021 209 citations C.H. Arrowsmith, Linda Z. Penn et al. profile →
  7. Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation
    2022 134 citations Ashley Hutchinson, Yanjun Li et al. profile →

Peers

C.H. Arrowsmith
John D. Pfeifer United States
Stefan Knapp Germany
Shaomeng Wang United States
Stephen W. Fesik United States
S.K. Burley United States
J. Deisenhofer United States
Susan S. Taylor United States
Andrew G. W. Leslie United Kingdom
Antony W. Burgess Australia
Robert M. Stroud United States
John D. Pfeifer United States
C.H. Arrowsmith
Citations per year, relative to C.H. Arrowsmith C.H. Arrowsmith (= 1×) peers John D. Pfeifer

Countries citing papers authored by C.H. Arrowsmith

Since Specialization
Citations

This map shows the geographic impact of C.H. Arrowsmith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by C.H. Arrowsmith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites C.H. Arrowsmith more than expected).

Fields of papers citing papers by C.H. Arrowsmith

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by C.H. Arrowsmith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by C.H. Arrowsmith. The network helps show where C.H. Arrowsmith may publish in the future.

Co-authorship network of co-authors of C.H. Arrowsmith

This figure shows the co-authorship network connecting the top 25 collaborators of C.H. Arrowsmith. A scholar is included among the top collaborators of C.H. Arrowsmith based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with C.H. Arrowsmith. C.H. Arrowsmith is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Pérez‐Vargas, Jimena, Antoine Désilets, Malihe Hassanzadeh, et al.. (2025). From N-0385 to N-0920: Unveiling a Host-Directed Protease Inhibitor with Picomolar Antiviral Efficacy against Prevalent SARS-CoV-2 Variants. Journal of Medicinal Chemistry. 68(7). 7119–7136. 2 indexed citations
2.
Maitland, Matthew E. R., Dominic D. G. Owens, Xu Wang, et al.. (2024). Interplay between β-propeller subunits WDR26 and muskelin regulates the CTLH E3 ligase supramolecular complex. Communications Biology. 7(1). 1668–1668. 5 indexed citations
3.
Medina, Tiago da Silva, Alex Murison, Michelle I. Smith, et al.. (2023). The chromatin and single-cell transcriptional landscapes of CD4 T cells in inflammatory bowel disease link risk loci with a proinflammatory Th17 cell population. Frontiers in Immunology. 14. 1161901–1161901. 7 indexed citations
4.
Harding, Rachel, Ivan Franzoni, Mandeep Mann, et al.. (2023). Discovery and characterization of a chemical probe targeting the zinc-finger ubiquitin-binding domain of HDAC6. Figshare. 1 indexed citations
5.
Hanley, Ronan P., Yan Nie, Fengling Li, et al.. (2023). Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2. Journal of the American Chemical Society. 145(14). 8176–8188. 32 indexed citations
6.
Kimani, Serah, Sumera Perveen, Hong Zeng, et al.. (2023). The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition. Communications Biology. 6(1). 1272–1272. 12 indexed citations
7.
Wang, Zifeng, Jessica Petricca, Sujun Chen, et al.. (2023). SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1. Proceedings of the National Academy of Sciences. 120(33). e2220472120–e2220472120. 9 indexed citations
8.
Arrowsmith, C.H., et al.. (2022). A conversation on using chemical probes to study protein function in cells and organisms. Nature Communications. 13(1). 3757–3757. 7 indexed citations
9.
Harding, Rachel, Justin C. Deme, Johannes F. Hevler, et al.. (2021). Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1. Communications Biology. 4(1). 1374–1374. 26 indexed citations
10.
Mann, Mandeep, Carlos Zepeda‐Velázquez, Aiping Dong, et al.. (2021). Structure–Activity Relationship of USP5 Inhibitors. Journal of Medicinal Chemistry. 64(20). 15017–15036. 13 indexed citations
11.
Han, Zhen, Levon Halabelian, Xiangkun Yang, et al.. (2020). Identification of lysine isobutyrylation as a new histone modification mark. Nucleic Acids Research. 49(1). 177–189. 48 indexed citations
12.
Harding, Rachel, Renato Ferreira de Freitas, P.M. Collins, et al.. (2017). Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin. Journal of Medicinal Chemistry. 60(21). 9090–9096. 29 indexed citations
13.
Dixit, Sugyan M., Tamuka M. Chidyausiku, Inna Goreshnik, et al.. (2017). Global analysis of protein folding using massively parallel design, synthesis, and testing. Science. 357(6347). 168–175. 305 indexed citations breakdown →
14.
Harrison, Joseph S., Evan M. Cornett, Dennis Goldfarb, et al.. (2016). Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1. eLife. 5. 98 indexed citations
15.
Das, Rhiju, Ingemar André, Yang Shen, et al.. (2009). Simultaneous prediction of protein folding and docking at high resolution. Proceedings of the National Academy of Sciences. 106(45). 18978–18983. 123 indexed citations
16.
Shen, Yang, Oliver F. Lange, Frank Delaglio, et al.. (2008). Consistent blind protein structure generation from NMR chemical shift data. Proceedings of the National Academy of Sciences. 105(12). 4685–4690. 669 indexed citations breakdown →
17.
Shago, Mary, Lilia Kaustov, Paul C. Boutros, et al.. (2007). CUL7 Is a Novel Antiapoptotic Oncogene. Cancer Research. 67(20). 9616–9622. 50 indexed citations
18.
Vedadi, Masoud, F. Niesen, Abdellah Allali‐Hassani, et al.. (2006). Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination. Proceedings of the National Academy of Sciences. 103(43). 15835–15840. 471 indexed citations
19.
Bochkareva, Elena, Lilia Kaustov, Ayeda Ayed, et al.. (2005). Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A. Proceedings of the National Academy of Sciences. 102(43). 15412–15417. 230 indexed citations
20.
Liu, Gaohua, Yang Shen, Hanudatta S. Atreya, et al.. (2005). NMR data collection and analysis protocol for high-throughput protein structure determination. Proceedings of the National Academy of Sciences. 102(30). 10487–10492. 90 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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