Walter W. Chen

9.5k citations

31 papers · 5.1k indexed · 5 hit papers · h-index 22

Impact in

Cancer Research top 1%
- Cancer, Hypoxia, and Metabolism
Molecular Biology top 2%
- Mitochondrial Function and Pathology
- Epigenetics and DNA Methylation
- Metabolism, Diabetes, and Cancer
- ATP Synthase and ATPases Research
- Metabolomics and Mass Spectrometry Studies
- RNA modifications and cancer

Papers in

Clinical Biochemistry 4
- Metabolism and Genetic Disorders 4
Aging 1

Co-authors: David M. Sabatini Timothy C. Wang Kıvanç Birsoy Elizaveta Freinkman Monther Abu-Remaileh Richard Possemato Sergei Musatov Donald W. Pfaff
Journals: Cell (5 papers)Proceedings of the National Academy of Sciences (3 papers)Platelets (2 papers)Nature (2 papers)Pathology (2 papers)
Partner nations: United States Australia Japan

In The Last Decade

Walter W. Chen

31 papers receiving 5.1k citations

Hit Papers

5 papers align trajectories log scale

mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient 2017 · 344 citations

Peers

Countries citing papers authored by Walter W. Chen

Since Specialization

Citations

This map shows the geographic impact of Walter W. Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Walter W. Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Walter W. Chen more than expected).

Fields of papers citing papers by Walter W. Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Walter W. Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Walter W. Chen. The network helps show where Walter W. Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside Walter W. Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Walter W. Chen Line = papers co-authored together Walter W. Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Technologies for Decoding Cancer Metabolism with Spatial Resolution Cold Spring Harbor Perspectives in Medicine ·Walter W. Chen, Michael E. Pacold, David M. Sabatini, Naama Kanarek	2024	2
2	MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme Nature Communications ·Yingzhong Li, Nikola A. Ivica, Ting Dong, Dimitrios Papageorgiou, Yanpu He, Douglas Brown, Marianna Kleyman, Guangan Hu, Walter W. Chen, Lucas B. Sullivan, Amanda Del Rosario, Paula T. Hammond, Matthew G. Vander Heiden, Jianzhu Chen	2020	32
3	A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human Cells iScience ·Graham J. Ray, Elizabeth A. Boydston, E. Z. Jan, Gregory A. Wyant, Sebastian Lourido, Walter W. Chen, David M. Sabatini	2020	29
4	An integrated approach to inherited platelet disorders: results from a research collaborative, the Sydney Platelet Group Pathology ·David J. Rabbolini, David Connor, Marie‐Christine Morel‐Kopp, Hannah Mitchell, Mayuko Kondo, Walter W. Chen, Marie‐Christine Alessi, William Stevenson, Vivien Chen, Joanne Joseph, Timothy Brighton, Christopher Wård	2020	15
5	MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo Proceedings of the National Academy of Sciences ·Erol C. Bayraktar, Lou Baudrier, A. Alsalmawy, Caroline A. Lewis, Sze Ham Chan, Tenzin Kunchok, Monther Abu-Remaileh, Andrew L. Cangelosi, David M. Sabatini, Kıvanç Birsoy, Walter W. Chen	2018	73
6	mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient Cell ·Gregory A. Wyant, Monther Abu-Remaileh, Rachel L. Wolfson, Walter W. Chen, Elizaveta Freinkman, Laura V. Danai, Matthew G. Vander Heiden, David M. Sabatini Hit paper breakdown →	2017	344
7	Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras Cell ·Timothy C. Wang, Haiyan Yu, Nicholas W. Hughes, Bingxu Liu, Arek Kendirli, Klara R. Klein, Walter W. Chen, Eric S. Lander, David M. Sabatini Hit paper breakdown →	2017	413
8	Rapid immunopurification of mitochondria for metabolite profiling and absolute quantification of matrix metabolites Nature Protocols ·Walter W. Chen, Elizaveta Freinkman, David M. Sabatini	2017	77
9	Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism Cell ·Walter W. Chen, Elizaveta Freinkman, Timothy C. Wang, Kıvanç Birsoy, David M. Sabatini Hit paper breakdown →	2016	337
10	Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness Science ·Pekka Katajisto, Morteza Fanoudi, Christine L. Chaffer, Nalle Pentinmikko, Nemanja D. Marjanovic, Sharif Iqbal, Roberto Zoncu, Walter W. Chen, Robert A. Weinberg, David M. Sabatini	2015	390
11	Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness PMC ·Pekka Katajisto, Morteza Fanoudi, Christine L. Chaffer, Nalle Pentinmikko, Nemanja D. Marjanovic, Sharif Iqbal, Roberto Zoncu, Walter W. Chen, Robert A. Weinberg, David M. Sabatini	2015	1
12	An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis Cell ·Kıvanç Birsoy, Timothy C. Wang, Walter W. Chen, Elizaveta Freinkman, Monther Abu-Remaileh, David M. Sabatini Hit paper breakdown →	2015	956
13	SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance Nature ·Do‐Hoon Kim, Brian P. Fiske, Kıvanç Birsoy, Elizaveta Freinkman, Kenjiro Kami, Richard Possemato, Yakov Chudnovsky, Michael E. Pacold, Walter W. Chen, Jason R. Cantor, Laura M. Shelton, Dan Y. Gui, Manjae Kwon, Shakti Ramkissoon, Keith L. Ligon, Seong Woo Kang, Matija Snuderl, Matthew G. Vander Heiden, David M. Sabatini	2015	273
14	Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides Nature ·Kıvanç Birsoy, Richard Possemato, Franziska K. Lorbeer, Erol C. Bayraktar, Prathapan Thiru, Burcu Yücel, Timothy C. Wang, Walter W. Chen, Clary B. Clish, David M. Sabatini Hit paper breakdown →	2014	558
15	Inhibition of ATPIF1 Ameliorates Severe Mitochondrial Respiratory Chain Dysfunction in Mammalian Cells Cell Reports ·Walter W. Chen, Kıvanç Birsoy, Maria M. Mihaylova, Ramya HN, Chrysavgi Th. Kosolia, Burcu Yücel, Erol C. Bayraktar, Jan E. Carette, Clary B. Clish, Thijn R. Brummelkamp, David D. Sabatini, David M. Sabatini	2014	58
16	Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition Cell ·Yoav D. Shaul, Elizaveta Freinkman, William C. Comb, Jason R. Cantor, Wai Leong Tam, Prathapan Thiru, Do‐Hoon Kim, Naama Kanarek, Michael E. Pacold, Walter W. Chen, Brian Bierie, Richard Possemato, Ferenc Reinhardt, Robert A. Weinberg, Michael B. Yaffe, David M. Sabatini	2014	172
17	BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles Molecular Therapy — Nucleic Acids ·Walter W. Chen, Leonora Balaj, Linda M. Liau, Michael L. Samuels, Steve K. Kotsopoulos, Casey A. Maguire, 洋西井上, Horacio Soto, Matthew C. Garrett, Lin Zhu, Sarada Sivaraman, Clark Chen, Eric T. Wong, Bob S. Carter, Fred H. Hochberg, Xandra O. Breakefield, Johan Skog	2013	283
18	MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors Nature Genetics ·Kıvanç Birsoy, Timothy C. Wang, Richard Possemato, Ömer Yılmaz, Catherine Koch, Walter W. Chen, Xu Jinmei, Yetiş Gültekin, Timothy R. Peterson, Jan E. Carette, Thijn R. Brummelkamp, Clary B. Clish, David M. Sabatini	2012	191
19	Enhanced Phosphatase Activity Attenuates α-Synucleinopathy in a Mouse Model Journal of Neuroscience ·Kang-Woo Lee, Walter W. Chen, Eunsung Junn, Joo-Young Im, Hilary Grosso Jasutkar, Patricia K. Sonsalla, 黄会林, Neelanjana Ray, José R. Fernández, Chao Yang, Eliezer Masliah, Michael Voronkov, Steven P. Braithwaite, Jeffry B. Stock, M. Maral Mouradian	2011	148
20	RNAi-mediated silencing of estrogen receptor α in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors Proceedings of the National Academy of Sciences ·Sergei Musatov, Walter W. Chen, Donald W. Pfaff, Michael G. Kaplitt, Sonoko Ogawa	2006	178

About Walter W. Chen

Walter W. Chen is a scholar working on Clinical Biochemistry, Aging, Hematology, Cancer Research and Behavioral Neuroscience, having authored 31 papers that have together received 5.1k indexed citations. Recurring topics across this work include Mitochondrial Function and Pathology (9 papers), Cancer, Hypoxia, and Metabolism (5 papers), Platelet Disorders and Treatments (5 papers), Metabolomics and Mass Spectrometry Studies (4 papers), Metabolism and Genetic Disorders (4 papers), ATP Synthase and ATPases Research (3 papers), Epigenetics and DNA Methylation (3 papers) and Blood groups and transfusion (3 papers). The work is most often cited by research in Cancer Research (1.6k citations), Molecular Biology (3.4k citations), Aging (81 citations), Endocrine and Autonomic Systems (268 citations) and Biochemistry (278 citations). Walter W. Chen has collaborated with scholars based in United States, Australia and Japan. Frequent co-authors include David M. Sabatini, Timothy C. Wang, Kıvanç Birsoy, Elizaveta Freinkman, Monther Abu-Remaileh, Richard Possemato, Sergei Musatov, Donald W. Pfaff, Sonoko Ogawa and Michael G. Kaplitt. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences, Platelets, Nature and Pathology.

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