Seth L. Masters

28.4k citations

99 papers · 10.4k indexed · 6 hit papers · h-index 50

Impact in

Immunology top 0.2%
- interferon and immune responses
- Immune Response and Inflammation
- IL-33, ST2, and ILC Pathways
- Immune Cell Function and Interaction
Nephrology top 0.5%
- Gout, Hyperuricemia, Uric Acid

Papers in

Immunology 72
- interferon and immune responses 29
- Immune Response and Inflammation 16
- IL-33, ST2, and ILC Pathways 12
- Immune Cell Function and Interaction 11
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms 8
Biological Psychiatry 3

Co-authors: Daniel L. Kastner Luke O'neill Ivona Aksentijevich Anna Simon Motti Gerlic Adrian Liston Moritz Haneklaus Kate Schroder
Journals: The Journal of Immunology (5 papers)Journal of Biological Chemistry (5 papers)Cell Reports (4 papers)The Journal of Experimental Medicine (4 papers)Nature Communications (3 papers)
Partner nations: Australia United States Germany

In The Last Decade

Seth L. Masters

98 papers receiving 10.3k citations

Hit Papers

6 papers align trajectories log scale

Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants 2025 · 24 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2025 Nature Immunology
2020 Cell Reports
2017 Proceedings of the National Academy of Sciences
2017 Journal of Hepatology
2015 Nature Communications
2009 Annual Review of Immunology

Peers

Countries citing papers authored by Seth L. Masters

Since Specialization

Citations

This map shows the geographic impact of Seth L. Masters's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Seth L. Masters with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Seth L. Masters more than expected).

Fields of papers citing papers by Seth L. Masters

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Seth L. Masters. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Seth L. Masters. The network helps show where Seth L. Masters may publish in the future.

Co-authors

The 25 scholars most cited alongside Seth L. Masters, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Seth L. Masters Line = papers co-authored together Seth L. Masters links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	NLRP3 inflammasome–driven hemophagocytic lymphohistiocytosis occurs independent of IL-1β and IL-18 and is targetable by BET inhibitors Science Advances ·Kevin Meisner, Muhamad Kusuma Minarta, Anupriya Jain, Xiuquan Ma, James Rickard, Barbara Leonard Gibson, Catherine N. Hall, Andrew J. Kueh, Seth L. Masters, Inmaculada Rioja, Rab K. Prinjha, Marcel Doerflinger, Kate E. Lawlor, Maryam Rashidi, James E. Vince	2025	0
2	Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants Nature Immunology ·Shouya Feng, 憲彦柴田, Katja Hrovat-Schaale, 永野幸四郎, Yaoyuan Zhang, Alyxandra Carla de Medeiros Batista, Paul J. Baker, А. В. Бойко, Annemarie Steiner, Dominic De Nardo, Dhanya Lakshmi Narayanan, Florian Milhavet, Alberto Pinzón‐Charry, Juan I. Aróstegui, Raju Khubchandani, Matthias Geyer, Guilaine Boursier, Seth L. Masters Hit paper breakdown →	2025	24
3	Heterozygous de novo dominant negative mutation of REXO2 results in interferonopathy Nature Communications ·Elina Idiiatullina, Mahmoud Al‐Azab, Zuliani Mahmood, Katja Hrovat-Schaale, Ziyang Liu, Xiaotian Li, I. Lundströam, 裕俊石渡, В.И. Кузьмин, Song Gao, Jun Cui, Wenhao Zhou, Li Liu, Yuxia Zhang, Seth L. Masters	2024	1
4	G-CSF drives autoinflammation in APLAID Nature Immunology ·John-Roger, Bruce M. Pringle, Juan I. Aróstegui, Ashley P. Ng, Jordanna S. VERAS, Waruni Abeysekera, Alexandra L. Garnham, Sze‐Ling Ng, Paul J. Baker, Jacob T. Jackson, John D. Lich, Margaret L. Hibbs, Ian P. Wicks, Cynthia Louis, Seth L. Masters	2023	10
5	Organellar homeostasis and innate immune sensing Nature reviews. Immunology ·Cassandra R. Harapas, Elina Idiiatullina, Mahmoud Al‐Azab, Katja Hrovat-Schaale, А. В. Бойко, Annemarie Steiner, Pawat Laohamonthonkul, Sophia Davidson, Chien‐Hsiung Yu, Lee M. Booty, Seth L. Masters	2022	104
6	Deficiency in coatomer complex I causes aberrant activation of STING signalling Nature Communications ·Annemarie Steiner, Katja Hrovat-Schaale, Ignazia Prigione, Chien‐Hsiung Yu, Pawat Laohamonthonkul, Cassandra R. Harapas, Ronnie Ren Jie Low, Dominic De Nardo, Laura F. Dagley, Michael J. Mlodzianoski, Kelly L. Rogers, Thomas Zillinger, Gunther Hartmann, Michael P. Gantier, Marco Gattorno, Matthias Geyer, Stefano Volpi, Sophia Davidson, Seth L. Masters	2022	63
7	Small Extracellular Vesicle Enrichment of a Retrotransposon-Derived Double-Stranded RNA: A Means to Avoid Autoinflammation? Biomedicines ·Estefanía Yanina Vergara Velásquez, Alexandra L. Garnham, Andrew D. Foers, Lesley Cheng, Seth L. Masters, Ken C. Pang	2021	4
8	The role of PLCγ2 in immunological disorders, cancer, and neurodegeneration Journal of Biological Chemistry ·Jacob T. Jackson, John-Roger, Stephen L. Nutt, Seth L. Masters	2021	64
9	Differential recognition of HIV-stimulated IL-1β and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages PLoS Pathogens ·Kathy Triantafilou, Christopher J. Ward, V. P. Grekov, Robert G. Ferris, Emma Koppe, Curt D. Haffner, Vincent Piguet, Vipulkumar K. Patel, Heather Amrine‐Madsen, Louise K. Modis, Seth L. Masters, Martha Triantafilou	2021	24
10	NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS The Journal of Experimental Medicine ·Cynthia Louis, Fernando Souza-Fonseca-Guimarães, Yuyan Yang, Damian B. D’Silva, Tobias Kratina, Laura F. Dagley, Soroor Hediyeh-zadeh, Jai Rautela, Seth L. Masters, Melissa J. Davis, Jeffrey J. Babon, Bogoljub Ćirić, Éric Vivier, Warren S. Alexander, Nicholas D. Huntington, Ian P. Wicks	2020	65
11	Inhibition of interleukin‐1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis Clinical & Translational Immunology ·Dragana Dragoljevic, Gina Bloodworth, Cynthia Louis, Waled Shihata, Michael J. Kraakman, Dwisa Taztia Susfi, Seth L. Masters, Beatriz Y. Hanaoka, Prabhakara R. Nagareddy, Graeme I. Lancaster, Ian P. Wicks, Andrew Murphy	2020	14
12	SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm The Journal of Immunology ·Tan Nguyen, K Sandya, Kirstin Elgass, Sarah J. Creed, Shane Cheung, Michelle D. Tate, Gabrielle T. Belz, Ian P. Wicks, Seth L. Masters, Ken C. Pang	2019	34
13	Ximmer: a system for improving accuracy and consistency of CNV calling from exome data GigaScience ·Simon Sadedin, Justine A. Ellis, Seth L. Masters, Alicia Oshlack	2018	19
14	Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner Proceedings of the National Academy of Sciences ·Stephanie A. Conos, Kaiwen Chen, Dominic De Nardo, Hideki Hara, Lachlan Whitehead, Gabriel Núñez, Seth L. Masters, James M. Murphy, Kate Schroder, David L. Vaux, Kate E. Lawlor, Lisa Lindqvist, James E. Vince Hit paper breakdown →	2017	377
15	Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome The Journal of Experimental Medicine ·Viola Neudecker, Moritz Haneklaus, Owen Jensen, Ludmila Khailová, Joanne C. Masterson, Hazel Tye, Kathryn A. Biette, Paul Jedlicka, Kelley S. Brodsky, Mark E. Gerich, Matthias Mack, Avril A. B. Robertson, Matthew A. Cooper, Glenn T. Furuta, Charles A. Dinarello, Luke O'neill, Holger K. Eltzschig, Seth L. Masters, Eóin N. McNamee	2017	305
16	Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition Physiological Reviews ·Paul J. Baker, Dominic De Nardo, Fiona Moghaddas, Le Son Tran, Annabell Bachem, Tan Nguyen, Thomas J. Hayman, Hazel Tye, James E. Vince, Sammy Bedoui, Richard L. Ferrero, Seth L. Masters	2017	62
17	Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β The Journal of Experimental Medicine ·Wallis Christopher, Jae Jin Chae, Yong Hwan Park, Dominic De Nardo, Roslynn A. Stirzaker, Hyun‐Ja Ko, Hazel Tye, Louise H. Cengia, Ladina DiRago, Donald Metcalf, Andrew W. Roberts, Daniel L. Kastner, Andrew M. Lew, Dena Lyras, Benjamin T. Kile, Ben A. Croker, Seth L. Masters	2015	107
18	An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell eLife ·Michael Coffey, Brad E. Sleebs, Alessandro D. Uboldi, Alexandra L. Garnham, Magdalena Franco, Nicole D. Marino, Michael W. Panas, David Ferguson, Marta Enciso, Matthew T. O’Neill, Sash Lopaticki, Rebecca J. Stewart, Grant Dewson, Gordon K. Smyth, Brian J. Smith, Seth L. Masters, John C. Boothroyd, Justin A. Boddey, Christopher J. Tonkin	2015	83
19	The Pathogen Candida albicans Hijacks Pyroptosis for Escape from Macrophages mBio ·Nathalie Uwamahoro, Jiyoti Verma‐Gaur, Hsin‐Hui Shen, Yue Qu, Rowena S. Lewis, Jingxiong Lu, Keith R. Bambery, Seth L. Masters, James E. Vince, Thomas Naderer, Ana Traven	2014	206
20	24 hour intragastric acidity during maintenance treatment with ranitidine. BMJ ·Santiago Gómez Sáez, Bhawna Sharma, R E Pounder, Elizabeth C. Wood, Seth L. Masters, Monique Talbot	1984	9

About Seth L. Masters

Seth L. Masters is a scholar working on Immunology, Biological Psychiatry, Molecular Biology, Nephrology and Parasitology, having authored 99 papers that have together received 10.4k indexed citations. Recurring topics across this work include Inflammasome and immune disorders (60 papers), interferon and immune responses (29 papers), Immune Response and Inflammation (16 papers), IL-33, ST2, and ILC Pathways (12 papers), Immune Cell Function and Interaction (11 papers), Neutrophil, Myeloperoxidase and Oxidative Mechanisms (8 papers), Autoimmune and Inflammatory Disorders Research (7 papers) and RNA regulation and disease (6 papers). The work is most often cited by research in Immunology (4.7k citations), Nephrology (753 citations), Molecular Biology (7.0k citations), Parasitology (429 citations) and Hematology (705 citations). Seth L. Masters has collaborated with scholars based in Australia, United States and Germany. Frequent co-authors include Daniel L. Kastner, Luke O'neill, Ivona Aksentijevich, Anna Simon, Motti Gerlic, Adrian Liston, Moritz Haneklaus, Kate Schroder, Dominic De Nardo and Matthew A. Cooper. Their work appears in journals such as The Journal of Immunology, Journal of Biological Chemistry, Cell Reports, The Journal of Experimental Medicine and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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