Dena Lyras

10.5k total citations · 4 hit papers
147 papers, 7.0k citations indexed

About

Dena Lyras is a scholar working on Infectious Diseases, Molecular Biology and Public Health, Environmental and Occupational Health. According to data from OpenAlex, Dena Lyras has authored 147 papers receiving a total of 7.0k indexed citations (citations by other indexed papers that have themselves been cited), including 121 papers in Infectious Diseases, 32 papers in Molecular Biology and 29 papers in Public Health, Environmental and Occupational Health. Recurrent topics in Dena Lyras's work include Clostridium difficile and Clostridium perfringens research (117 papers), Antimicrobial Resistance in Staphylococcus (38 papers) and Streptococcal Infections and Treatments (28 papers). Dena Lyras is often cited by papers focused on Clostridium difficile and Clostridium perfringens research (117 papers), Antimicrobial Resistance in Staphylococcus (38 papers) and Streptococcal Infections and Treatments (28 papers). Dena Lyras collaborates with scholars based in Australia, United States and United Kingdom. Dena Lyras's co-authors include Julian I. Rood, Glen P. Carter, Vicki Adams, Milena M. Awad, D. Borden Lacy, Wiep Klaas Smits, Mark H. Wilcox, Ed J. Kuijper, Kate E. Mackin and Pauline M. Howarth and has published in prestigious journals such as Nature, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Dena Lyras

143 papers receiving 6.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Clostridium difficile infection

2016 599 citations Dena Lyras, D. Borden Lacy et al. profile →
Toxin B is essential for virulence of Clostridium difficile

2009 589 citations Dena Lyras, Pauline M. Howarth et al. Nature profile →
Expansion of the Clostridium perfringens toxin-based typing scheme

2018 399 citations Julian I. Rood, Vicki Adams et al. profile →
Translocation and dissemination of commensal bacteria in post-stroke infection

2016 334 citations Yogitha N. Srikhanta, Dena Lyras et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Dena Lyras Australia	43	5.0k	2.0k	1.7k	957	727	147	7.0k
Ying Taur United States	35	3.6k 0.7×	4.6k 2.3×	1.6k 1.0×	525 0.5×	305 0.4×	93	7.8k
J. Glenn Songer United States	45	5.2k 1.0×	1.5k 0.7×	1.4k 0.8×	360 0.4×	1.1k 1.5×	102	6.8k
T D Wilkins United States	48	4.6k 0.9×	2.3k 1.1×	1.2k 0.7×	721 0.8×	340 0.5×	116	7.7k
Carles Úbeda Spain	37	3.3k 0.7×	5.8k 2.8×	1.2k 0.7×	520 0.5×	290 0.4×	56	9.3k
S. P. Borriello United Kingdom	38	3.0k 0.6×	1.5k 0.7×	1.4k 0.8×	509 0.5×	235 0.3×	118	5.8k
Maja Rupnik Slovenia	46	7.1k 1.4×	1.8k 0.9×	3.4k 2.0×	1.2k 1.3×	125 0.2×	167	8.2k
Ian R. Poxton United Kingdom	38	2.1k 0.4×	1.3k 0.6×	1.5k 0.9×	496 0.5×	241 0.3×	153	5.1k
Rosa del Campo Spain	40	1.7k 0.3×	2.3k 1.1×	1.1k 0.6×	340 0.4×	453 0.6×	205	5.9k
Julian I. Rood Australia	63	9.1k 1.8×	3.6k 1.8×	1.7k 1.0×	716 0.7×	2.6k 3.6×	239	13.9k
Lucy S. Tompkins United States	55	2.5k 0.5×	2.3k 1.1×	1.6k 0.9×	3.7k 3.9×	629 0.9×	103	10.1k

Countries citing papers authored by Dena Lyras

Since Specialization

Citations

This map shows the geographic impact of Dena Lyras's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dena Lyras with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dena Lyras more than expected).

Fields of papers citing papers by Dena Lyras

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dena Lyras. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dena Lyras. The network helps show where Dena Lyras may publish in the future.

Co-authorship network of co-authors of Dena Lyras

This figure shows the co-authorship network connecting the top 25 collaborators of Dena Lyras. A scholar is included among the top collaborators of Dena Lyras based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dena Lyras. Dena Lyras is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Gulliver, Emily L., Dinesh Subedi, Nathan R. Campbell, et al.. (2025). Isolation, engineering and ecology of temperate phages from the human gut. Nature. 647(8090). 698–705. 1 indexed citations

Awad, Milena M., et al.. (2024). A Clostridioides difficile endolysin modulates toxin secretion without cell lysis. Communications Biology. 7(1). 1044–1044. 1 indexed citations

Kochan, Kamila, Xenia Kostoulias, Anton Y. Peleg, et al.. (2024). A Multimodal Spectroscopic Approach Combining Mid-infrared and Near-infrared for Discriminating Gram-positive and Gram-negative Bacteria. Analytical Chemistry. 96(46). 18392–18400. 5 indexed citations

Karpe, Avinash V., M. Hutton, Steven J. Mileto, et al.. (2023). Gut Microbial Perturbation and Host Response Induce Redox Pathway Upregulation along the Gut–Liver Axis during Giardiasis in C57BL/6J Mouse Model. International Journal of Molecular Sciences. 24(2). 1636–1636. 7 indexed citations

Srikhanta, Yogitha N., M. Hutton, Chaille T. Webb, et al.. (2023). Design, Synthesis, and Evaluation of Cephamycin-Based Antisporulation Agents targeting Clostridioides difficile. Journal of Medicinal Chemistry. 67(1). 450–466. 4 indexed citations

Kay, Callum, Shouya Feng, Daniel Enosi Tuipulotu, et al.. (2022). Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins. Science Immunology. 7(71). eabm1803–eabm1803. 25 indexed citations

Hamiot, Audrey, Jessica A. Wisniewski, Rommel A. Mathias, et al.. (2022). A Highly Specific Holin-Mediated Mechanism Facilitates the Secretion of Lethal Toxin TcsL in Paeniclostridium sordellii. Toxins. 14(2). 124–124. 4 indexed citations

Vezina, Ben, Theo R. Allnutt, Anthony L. Keyburn, et al.. (2021). Stable Recombinant-Gene Expression from a Ligilactobacillus Live Bacterial Vector via Chromosomal Integration. Applied and Environmental Microbiology. 87(11). 5 indexed citations

Putsathit, Papanin, M. Hutton, Katherine A. Hammer, et al.. (2021). Cationic Peptidomimetic Amphiphiles Having a N-Aryl- or N-Naphthyl-1,2,3-Triazole Core Structure Targeting Clostridioides (Clostridium) difficile: Synthesis, Antibacterial Evaluation, and an In Vivo C. difficile Infection Model. Antibiotics. 10(8). 913–913. 8 indexed citations

10.

Turner, Robert D., Aline Rifflet, Andrew Nichols, et al.. (2021). PGFinder, a novel analysis pipeline for the consistent, reproducible, and high-resolution structural analysis of bacterial peptidoglycans. eLife. 10. 17 indexed citations

11.

Mohamed, Ahmed M., Cécile Morlot, Milena M. Awad, et al.. (2020). A dynamic, ring-forming MucB / RseB-like protein influences spore shape in Bacillus subtilis. PLoS Genetics. 16(12). e1009246–e1009246. 3 indexed citations

12.

Mileto, Steven J., Thierry Jardé, Kevin O. Childress, et al.. (2020). Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease. Proceedings of the National Academy of Sciences. 117(14). 8064–8073. 75 indexed citations

13.

Bulach, Dieter, et al.. (2019). Paeniclostridium sordellii and Clostridioides difficile encode similar and clinically relevant tetracycline resistance loci in diverse genomic locations. BMC Microbiology. 19(1). 53–53. 11 indexed citations

14.

Draxler, Dominik F., Milena M. Awad, Maria Daglas, et al.. (2019). Tranexamic Acid Influences the Immune Response, but not Bacterial Clearance in a Model of Post-Traumatic Brain Injury Pneumonia. Journal of Neurotrauma. 36(23). 3297–3308. 21 indexed citations

15.

Watts, Thomas D., et al.. (2019). Virulence Plasmids of the Pathogenic Clostridia. Microbiology Spectrum. 7(3). 14 indexed citations

16.

Larcombe, Sarah, et al.. (2018). Clostridium sordellii outer spore proteins maintain spore structural integrity and promote bacterial clearance from the gastrointestinal tract. PLoS Pathogens. 14(4). e1007004–e1007004. 8 indexed citations

17.

Chae, Jae Jin, Yong Hwan Park, Dominic De Nardo, et al.. (2015). Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β. The Journal of Experimental Medicine. 212(6). 927–938. 107 indexed citations

18.

Rimoldi, Guillermo, Francisco A. Uzal, R. P. Chin, et al.. (2015). Necrotic Enteritis in Chickens Associated withClostridium sordellii. Avian Diseases. 59(3). 447–451. 17 indexed citations

19.

Awad, Milena M., et al.. (2014). Antibiotic resistance, virulence factors and genetics of Clostridium sordellii. Research in Microbiology. 166(4). 368–374. 33 indexed citations

20.

Carter, Glen P., Milena M. Awad, Yibai Hao, et al.. (2011). TcsL Is an Essential Virulence Factor inClostridium sordelliiATCC 9714. Infection and Immunity. 79(3). 1025–1032. 45 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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