Grant Dewson

14.5k citations

81 papers · 7.2k indexed · 5 hit papers · h-index 46

Impact in

Molecular Biology top 1%
- Cell death mechanisms and regulation
- RNA Interference and Gene Delivery
- Mitochondrial Function and Pathology
- ATP Synthase and ATPases Research
- Ubiquitin and proteasome pathways
Immunology top 2%
- Immune Cell Function and Interaction

Papers in ⓘ

Immunology 20
Molecular Biology 63
- Cell death mechanisms and regulation 48
- RNA Interference and Gene Delivery 22
- Mitochondrial Function and Pathology 20
- ATP Synthase and ATPases Research 10
- Ubiquitin and proteasome pathways 6

Co-authors: Ruth M. Kluck (27 shared papers)Dana Westphal (9 shared papers)Jerry M. Adams (8 shared papers)Peter E. Czabotar (15 shared papers)David C.S. Huang (9 shared papers)Simon N. Willis (2 shared papers)Edwina Naik (2 shared papers)Chen Lin (1 shared paper)
Journals: Cell Death and Differentiation (10 papers)Blood (6 papers)Cell Death and Disease (5 papers)Molecular Cell (5 papers)Cold Spring Harbor Protocols (5 papers)
Partner nations: Australia United Kingdom United States

In The Last Decade

Grant Dewson

80 papers receiving 7.2k citations

Hit Papers

5 papers align trajectories log scale

Mitochondria and cell death 2024 · 171 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2024 Nature Cell Biology
2023 Nature reviews. Cancer
2021 Cell Death and Differentiation
2013 Cell
2005 Genes & Development

Peers

Countries citing papers authored by Grant Dewson

Since Specialization

Citations

This map shows the geographic impact of Grant Dewson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Grant Dewson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Grant Dewson more than expected).

Fields of papers citing papers by Grant Dewson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Grant Dewson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Grant Dewson. The network helps show where Grant Dewson may publish in the future.

Co-authors

The 25 scholars most cited alongside Grant Dewson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Grant Dewson Line = papers co-authored together Grant Dewson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 81 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x _L , but not Bcl-2, until displaced by BH3-only proteins Genes & Development ·Simon N. Willis, Chen Lin, Grant Dewson, Andrew H. Wei, Edwina Naik, Jamie I. Fletcher, Jerry M. Adams, David C.S. Huang Hit paper breakdown →	2005	1024
2	Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis Cell ·Peter E. Czabotar, Dana Westphal, Grant Dewson, Stephen Ma, Colin Hockings, W. Douglas Fairlie, Erinna F. Lee, Shenggen Yao, A.Y. Robin, Brian J. Smith, David C.S. Huang, Ruth M. Kluck, Jerry M. Adams, Peter M. Colman Hit paper breakdown →	2013	444
3	Molecular biology of Bax and Bak activation and action Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·Dana Westphal, Grant Dewson, Peter E. Czabotar, Ruth M. Kluck	2010	430
4	Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis Cell Death and Differentiation ·Dana Westphal, Ruth M. Kluck, Grant Dewson	2013	337
5	Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis Journal of Cell Science ·Grant Dewson, Ruth M. Kluck	2009	277
6	To Trigger Apoptosis, Bak Exposes Its BH3 Domain and Homodimerizes via BH3:Groove Interactions Molecular Cell ·Grant Dewson, Tobias Kratina, Huiyan W. Sim, Hamsa Puthalakath, Jerry M. Adams, Peter M. Colman, Ruth M. Kluck	2008	266
7	Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities Cell Death and Differentiation ·Marlene F. Schmidt, Zhong Yan Gan, David Komander, Grant Dewson Hit paper breakdown →	2021	245
8	Parkin and mitophagy in cancer Oncogene ·Jonathan P. Bernardini, Michael Lazarou, Grant Dewson	2016	221
9	Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1 Nature Immunology ·Nicholas D. Huntington, Hamsa Puthalakath, Priscilla Gunn, Edwina Naik, Ewa M. Michalak, Mark J. Smyth, Hyacinth Tabarias, Mariapia A. Degli‐Esposti, Grant Dewson, Simon N. Willis, Noboru Motoyama, David C.S. Huang, Stephen L. Nutt, David M. Tarlinton, Andreas Strasser	2007	216
10	Bak Activation for Apoptosis Involves Oligomerization of Dimers via Their α6 Helices Molecular Cell ·Grant Dewson, Tobias Kratina, Peter E. Czabotar, Catherine L. Day, Jerry M. Adams, Ruth M. Kluck	2009	175
11	Mitochondria and cell death Nature Cell Biology ·Hannah L. Glover, Annabell Schreiner, Grant Dewson, Stephen W. G. Tait Hit paper breakdown →	2024	171
12	Deubiquitinases in cancer Nature reviews. Cancer ·Grant Dewson, Pieter J.A. Eichhorn, David Komander Hit paper breakdown →	2023	149
13	Bax dimerizes via a symmetric BH3:groove interface during apoptosis Cell Death and Differentiation ·Grant Dewson, Stephen Ma, Paul Frederick, Colin Hockings, Iris K. L. Tan, Tobias Kratina, Ruth M. Kluck	2011	149
14	Mesenchymal stromal cell apoptosis is required for their therapeutic function Nature Communications ·Swee Heng Milon Pang, Joshua D’Rozario, Senora Mendonca, Tejasvini Bhuvan, Natalie L. Payne, Di Zheng, A. Hisana, Georgia Wallis, Adele Barugahare, David Powell, Jai Rautela, Nicholas D. Huntington, Grant Dewson, David C.S. Huang, Daniel H.D. Gray, Tracy Heng	2021	142
15	Mitochondrial Release of Pro-apoptotic Proteins Journal of Biological Chemistry ·Rachel T. Uren, Grant Dewson, Christine Bonzon, Trevor Lithgow, Donald D. Newmeyer, Ruth M. Kluck	2004	141
16	Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers Molecular Cell ·Jason M. Brouwer, Dana Westphal, Grant Dewson, A.Y. Robin, Rachel T. Uren, Ray C. Bartolo, Geoff Thompson, Peter M. Colman, Ruth M. Kluck, Peter E. Czabotar	2014	128
17	Activation mechanism of PINK1 Nature ·Zhong Yan Gan, Sylvie Callegari, Simon A. Cobbold, Thomas R. Cotton, Michael J. Mlodzianoski, Alexander F. Schubert, Niall D. Geoghegan, Kelly L. Rogers, Andrew Leis, Grant Dewson, Alisa Glukhova, David Komander	2021	117
18	Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function Cell Death and Differentiation ·Stephen Ma, Thanh Ngoc Nguyen, Iris K. L. Tan, Robert L. Ninnis, Sweta Iyer, David A. Stroud, Marie Ménard, Ruth M. Kluck, Michael T. Ryan, Grant Dewson	2014	101
19	Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1 Proceedings of the National Academy of Sciences ·Ben A. Croker, Joanne A. O’Donnell, Cameron J. Nowell, Donald Metcalf, Grant Dewson, Kirsteen J. Campbell, Kelly L. Rogers, Yifang Hu, Gordon K. Smyth, Jian‐Guo Zhang, M. J. D. White, Kurt Lackovic, Louise H. Cengia, Lorraine A. O’Reilly, Philippe Bouillet, Suzanne Cory, Andreas Strasser, Andrew W. Roberts	2011	100
20	Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak The Journal of Cell Biology ·Rachel T. Uren, Grant Dewson, Lin Chen, Stephanie C. Coyne, David C.S. Huang, Jerry M. Adams, Ruth M. Kluck	2007	100

About Grant Dewson

Grant Dewson is a scholar working on Immunology, Molecular Biology, Immunology and Allergy, Physiology and Oncology, having authored 81 papers that have together received 7.2k indexed citations. Recurring topics across this work include Cell death mechanisms and regulation (48 papers), RNA Interference and Gene Delivery (22 papers), Mitochondrial Function and Pathology (20 papers), ATP Synthase and ATPases Research (10 papers), Autophagy in Disease and Therapy (9 papers), Asthma and respiratory diseases (6 papers), Cancer-related Molecular Pathways (6 papers) and Ubiquitin and proteasome pathways (6 papers). The work is most often cited by research in Molecular Biology (5.3k citations), Immunology (1.3k citations), Cancer Research (671 citations), Oncology (1.1k citations) and Cell Biology (537 citations). Grant Dewson has collaborated with scholars based in Australia, United Kingdom and United States. Frequent co-authors include Ruth M. Kluck, Dana Westphal, Jerry M. Adams, Peter E. Czabotar, David C.S. Huang, Simon N. Willis, Edwina Naik, Chen Lin, Andrew H. Wei and Jamie I. Fletcher. Their work appears in journals such as Cell Death and Differentiation, Blood, Cell Death and Disease, Molecular Cell and Cold Spring Harbor Protocols.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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