James M. Murphy

26.1k citations

328 papers · 17.6k indexed · 3 hit papers · h-index 73

Impact in

Cellular and Molecular Neuroscience top 0.05%
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
Behavioral Neuroscience top 0.5%
- Stress Responses and Cortisol

Papers in

Cellular and Molecular Neuroscience 140
- Neurotransmitter Receptor Influence on Behavior 124
- Neuroscience and Neuropharmacology Research 68
Behavioral Neuroscience 22
- Stress Responses and Cortisol 22

Co-authors: William J. McBride Lawrence Lumeng Richard L. Bell T.-K. Li Zachary A. Rodd Satoshi Ikemoto Isabelle S. Lucet Gregory J. Gatto
Journals: Alcoholism Clinical and Experimental Research (36 papers)Alcohol (28 papers)Pharmacology Biochemistry and Behavior (25 papers)Biochemical Journal (15 papers)Nature Communications (13 papers)
Partner nations: United States Australia New Zealand

In The Last Decade

James M. Murphy

325 papers receiving 17.3k citations

Hit Papers

align trajectories log scale

Regulated necrosis in kidney ischemia-reperfusion injury 2019 · 253 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2019 Kidney International
2017 Proceedings of the National Academy of Sciences
2014 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by James M. Murphy

Since Specialization

Citations

This map shows the geographic impact of James M. Murphy's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James M. Murphy with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James M. Murphy more than expected).

Fields of papers citing papers by James M. Murphy

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James M. Murphy. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James M. Murphy. The network helps show where James M. Murphy may publish in the future.

Co-authorship network

The 25 scholars most cited alongside James M. Murphy, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James M. Murphy Line = papers co-authored together James M. Murphy links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The kinase domain of RIPK3 tunes its scaffolding functions Cell Death and Differentiation ·P. Wester, Christopher R. Horne, L. O. Androsova, Adele Preaudet, Adelia A. J. Aquino, Samuel N. Young, Park Jin-Hee, Sarah E. Garnish, Anne Hempel, Cathrine Hall, Joanne M. Hildebrand, K.R. Bhedi, 千鶴小川, Tracy L. Putoczki, Edwin D. Hawkins, Kenneth B. Edwards, James M. Murphy	2026	0
2	Inhibitors identify an auxiliary role for mTOR signalling in necroptosis execution downstream of MLKL activation Biochemical Journal ·Sarah E. Garnish, Christopher R. Horne, Yanxiang Meng, Samuel N. Young, Annette V. Jacobsen, Joanne M. Hildebrand, James M. Murphy	2024	2
3	Molecular dissection of the pseudokinase ZED1 expands effector recognition to the tomato immune receptor ZAR1 PLANT PHYSIOLOGY ·Kecia Huckstep, Maël Baudin, Ahmad Sururi, Lung‐Yu Liang, Weiwen Dai, James M. Murphy, Isabelle S. Lucet, Jana A. Hassan, Jennifer D. Lewis	2024	2
4	CaMKK2 as an emerging treatment target for bipolar disorder Molecular Psychiatry ·Madeleine Marante, Kévin Nay, Christopher R. Horne, REA REA, R SHODA, Paragulla Julio Vasquez, Douglas G. Whyte, Anthony R. Means, Ken Walder, Michael Berk, Anthony J. Hannan, James M. Murphy, Mark A. Febbraio, Andrew L. Gundlach, John W. Scott	2023	9
5	Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization Nature Communications ·Yanxiang Meng, Sarah E. Garnish, Katherine A. Davies, Gregory Bernstein, Andrew Leis, Christopher R. Horne, Joanne M. Hildebrand, Vanessa Miller, Cheree Fitzgibbon, Samuel N. Young, Toby A. Dite, Laura F. Dagley, Aarya Venkat, Natarajan Kannan, Akiko Koide, Shohei Koide, Alisa Glukhova, Peter E. Czabotar, James M. Murphy	2023	22
6	Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL Cell Death and Differentiation ·Ashish Sethi, Christopher R. Horne, Cheree Fitzgibbon, Karyn L. Wilde, Katherine A. Davies, Sarah E. Garnish, Annette V. Jacobsen, André L. Samson, Joanne M. Hildebrand, Ahmad Z. Wardak, Peter E. Czabotar, Emma J. Petrie, Paul R. Gooley, James M. Murphy	2022	27
7	Human RIPK3 C-lobe phosphorylation is essential for necroptotic signaling Cell Death and Disease ·Yanxiang Meng, Christopher R. Horne, André L. Samson, Laura F. Dagley, Samuel N. Young, Jarrod J. Sandow, Peter E. Czabotar, James M. Murphy	2022	19
8	Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis Nature Communications ·Yanxiang Meng, Katherine A. Davies, Cheree Fitzgibbon, Samuel N. Young, Sarah E. Garnish, Christopher R. Horne, Cindy S. Luo, Jean‐Marc Garnier, Lung‐Yu Liang, Angus D. Cowan, André L. Samson, Guillaume Lessène, Jarrod J. Sandow, Peter E. Czabotar, James M. Murphy	2021	67
9	A toolbox for imaging RIPK1, RIPK3, and MLKL in mouse and human cells Cell Death and Differentiation ·André L. Samson, Cheree Fitzgibbon, L. O. Androsova, Joanne M. Hildebrand, Lachlan Whitehead, 黄承林, Annette V. Jacobsen, Christopher R. Horne, Evridiki Loukidou, Samuel N. Young, Kelly L. Rogers, Edwin D. Hawkins, James M. Murphy	2021	43
10	Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix Nature Communications ·Michael R. Oliver, Christopher R. Horne, Safal Shrestha, J.R. Keown, Lung‐Yu Liang, Samuel N. Young, Jarrod J. Sandow, Andrew I. Webb, David C. Goldstone, Isabelle S. Lucet, Natarajan Kannan, Peter Metcalf, James M. Murphy	2021	5
11	The regulation of necroptosis by post-translational modifications Cell Death and Differentiation ·Yanxiang Meng, Jarrod J. Sandow, Peter E. Czabotar, James M. Murphy	2021	89
12	Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid–binding residues Science Signaling ·Kelan Chen, Richard W. Birkinshaw, حسین رحیمی, R Grinberg, Ruoyun Wang, Megan Iminitoff, Jarrod J. Sandow, Samuel N. Young, Patrick J. Hennessy, Tracy A. Willson, Vahid Rahimi, Andrew I. Webb, Marnie E. Blewitt, Peter E. Czabotar, James M. Murphy	2020	12
13	Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues Nature Communications ·Katherine A. Davies, Cheree Fitzgibbon, Samuel N. Young, Sarah E. Garnish, Wayland Yeung, Yinxi Sa, Richard W. Birkinshaw, Jarrod J. Sandow, Tran Nhu Ngoc, Lung‐Yu Liang, Isabelle S. Lucet, James D. Chalmers, Wayne M. Patrick, Natarajan Kannan, Emma J. Petrie, Peter E. Czabotar, James M. Murphy	2020	45
14	Structure-based mechanism of preferential complex formation by apoptosis signal–regulating kinases Science Signaling ·Xuehui Zhao, 一恵南, N. I. Zamyatin, B. Hoxhold, Andrew G Kramer, Benjamin L. Parker, David R. Croucher, Renwick C. J. Dobson, James M. Murphy, Peter D. Mace	2020	20
15	The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1β Release The Journal of Immunology ·Maryam Rashidi, Daniel S. Simpson, Anne Hempel, Daniel Frank, Emma J. Petrie, Hye-Jin Kim, Rebecca Feltham, Jane Murphy, Simon Chatfield, Guy S. Salvesen, James M. Murphy, Ian P. Wicks, James E. Vince	2019	97
16	Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters Nature Structural & Molecular Biology ·Natasha Jansz, Andrew Keniry, Marie Trussart, Heidi Bildsoe, Tamara Beck, Ian D. Tonks, Arne W. Mould, Peter F. Hickey, Kelsey Breslin, Megan Iminitoff, Matthew E. Ritchie, Edwina McGlinn, Graham F. Kay, James M. Murphy, Marnie E. Blewitt	2018	70
17	Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner Proceedings of the National Academy of Sciences ·Stephanie A. Conos, Kaiwen Chen, Dominic De Nardo, Hideki Hara, Lachlan Whitehead, Gabriel Núñez, Seth L. Masters, James M. Murphy, Kate Schroder, David L. Vaux, Kate E. Lawlor, Lisa Lindqvist, James E. Vince Hit paper breakdown →	2017	377
18	Epigenetic Regulator Smchd1 Functions as a Tumor Suppressor Cancer Research ·Huei San Leong, Kelan Chen, Yifang Hu, Stanley Chun-Wei Lee, Jason Corbin, Miha Pakusch, James M. Murphy, Ian J. Majewski, Gordon K. Smyth, Warren S. Alexander, Douglas J. Hilton, Marnie E. Blewitt	2012	36
19	Serotonin, dopamine and GABA involvement in alcohol drinking of selectively bred rats Alcohol ·William J. McBride, James M. Murphy, Lawrence Lumeng, T.-K. Li	1990	259
20	Monoamine uptake inhibitors attenuate ethanol intake in alcohol-preferring (P) rats Alcohol ·James M. Murphy, M.B. Waller, Gregory J. Gatto, William J. McBride, Lawrence Lumeng, T.-K. Li	1985	117

About James M. Murphy

James M. Murphy is a scholar working on Cellular and Molecular Neuroscience, Behavioral Neuroscience, Molecular Biology, Immunology and Cell Biology, having authored 328 papers that have together received 17.6k indexed citations. Recurring topics across this work include Neurotransmitter Receptor Influence on Behavior (124 papers), Neuroscience and Neuropharmacology Research (68 papers), Receptor Mechanisms and Signaling (61 papers), Cell death mechanisms and regulation (57 papers), Memory and Neural Mechanisms (23 papers), Stress Responses and Cortisol (22 papers), Adipose Tissue and Metabolism (21 papers) and Immune Response and Inflammation (17 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (7.9k citations), Behavioral Neuroscience (967 citations), Molecular Biology (9.5k citations), Immunology (2.8k citations) and Endocrine and Autonomic Systems (731 citations). James M. Murphy has collaborated with scholars based in United States, Australia and New Zealand. Frequent co-authors include William J. McBride, Lawrence Lumeng, Richard L. Bell, T.-K. Li, Zachary A. Rodd, Satoshi Ikemoto, Isabelle S. Lucet, Gregory J. Gatto, Zachary A. Rodd‐Henricks and Jeffrey J. Babon. Their work appears in journals such as Alcoholism Clinical and Experimental Research, Alcohol, Pharmacology Biochemistry and Behavior, Biochemical Journal and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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