Jae Jin Chae

13.5k total citations · 2 hit papers
40 papers, 4.7k citations indexed

About

Jae Jin Chae is a scholar working on Molecular Biology, Immunology and Genetics. According to data from OpenAlex, Jae Jin Chae has authored 40 papers receiving a total of 4.7k indexed citations (citations by other indexed papers that have themselves been cited), including 35 papers in Molecular Biology, 18 papers in Immunology and 6 papers in Genetics. Recurrent topics in Jae Jin Chae's work include Inflammasome and immune disorders (24 papers), interferon and immune responses (10 papers) and IL-33, ST2, and ILC Pathways (5 papers). Jae Jin Chae is often cited by papers focused on Inflammasome and immune disorders (24 papers), interferon and immune responses (10 papers) and IL-33, ST2, and ILC Pathways (5 papers). Jae Jin Chae collaborates with scholars based in United States, South Korea and Armenia. Jae Jin Chae's co-authors include Daniel L. Kastner, Ivona Aksentijevich, Geryl Wood, Yong Hwan Park, Geun‐Shik Lee, Seth L. Masters, Raphaela Goldbach‐Mansky, Ronald N. Germain, Naeha Subramanian and David B. Sacks and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and The Journal of Experimental Medicine.

In The Last Decade

Jae Jin Chae

39 papers receiving 4.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

2012 840 citations Geun‐Shik Lee, Naeha Subramanian et al. Nature profile →
Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS

2016 413 citations Yong Hwan Park, Geryl Wood et al. Nature Immunology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jae Jin Chae United States	24	3.9k	2.4k	665	659	516	40	4.7k
Matthew Mangan Germany	17	2.3k 0.6×	1.3k 0.5×	359 0.5×	315 0.5×	340 0.7×	26	3.9k
Andrea Dorfleutner United States	33	2.6k 0.7×	1.6k 0.6×	413 0.6×	283 0.4×	600 1.2×	47	3.7k
Laetitia Agostini Switzerland	5	2.2k 0.6×	1.5k 0.6×	298 0.4×	248 0.4×	258 0.5×	5	2.7k
Hidechika Okada Japan	32	987 0.3×	1.7k 0.7×	351 0.5×	352 0.5×	882 1.7×	142	3.7k
Dave Boucher Australia	17	2.5k 0.6×	1.3k 0.5×	275 0.4×	376 0.6×	182 0.4×	29	2.9k
Sun‐Sang J. Sung United States	33	873 0.2×	2.3k 0.9×	305 0.5×	379 0.6×	102 0.2×	87	4.0k
JoAnn Trial United States	36	1.7k 0.4×	793 0.3×	554 0.8×	113 0.2×	203 0.4×	75	4.0k
Dominic De Nardo Australia	26	2.1k 0.5×	1.9k 0.8×	208 0.3×	187 0.3×	112 0.2×	45	3.4k
Yolande Chvatchko Switzerland	27	1.6k 0.4×	1.7k 0.7×	384 0.6×	75 0.1×	305 0.6×	43	3.4k
Stéphanie Papin Switzerland	16	1.8k 0.5×	1.0k 0.4×	240 0.4×	256 0.4×	127 0.2×	25	2.2k

Countries citing papers authored by Jae Jin Chae

Since Specialization

Citations

This map shows the geographic impact of Jae Jin Chae's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jae Jin Chae with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jae Jin Chae more than expected).

Fields of papers citing papers by Jae Jin Chae

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jae Jin Chae. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jae Jin Chae. The network helps show where Jae Jin Chae may publish in the future.

Co-authorship network of co-authors of Jae Jin Chae

This figure shows the co-authorship network connecting the top 25 collaborators of Jae Jin Chae. A scholar is included among the top collaborators of Jae Jin Chae based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jae Jin Chae. Jae Jin Chae is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Lee, Wonyong, Deborah L. Stone, Patrycja Hoffmann, et al.. (2024). Interrupting an IFN-γ-dependent feedback loop in the syndrome of pyogenic arthritis with pyoderma gangrenosum and acne. Annals of the Rheumatic Diseases. 83(6). 787–798. 6 indexed citations

Stone, Deborah L., Amanda K. Ombrello, Juan I. Aróstegui, et al.. (2021). Excess Serum Interleukin‐18 Distinguishes Patients With Pathogenic Mutations in PSTPIP1 . Arthritis & Rheumatology. 74(2). 353–357. 25 indexed citations

Schnappauf, Oskar, Jae Jin Chae, Daniel L. Kastner, & Ivona Aksentijevich. (2019). The Pyrin Inflammasome in Health and Disease. Frontiers in Immunology. 10. 1745–1745. 233 indexed citations

Chung, Lawton K., Yong Hwan Park, Yueting Zheng, et al.. (2016). The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome. Cell Host & Microbe. 20(3). 296–306. 151 indexed citations

Park, Yong Hwan, Geryl Wood, Daniel L. Kastner, & Jae Jin Chae. (2016). Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS. Nature Immunology. 17(8). 914–921. 413 indexed citations breakdown →

Chae, Jae Jin, Yong Hwan Park, Dominic De Nardo, et al.. (2015). Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β. The Journal of Experimental Medicine. 212(6). 927–938. 107 indexed citations

Sokołowska, Milena, Li‐Yuan Chen, Yueqin Liu, et al.. (2015). Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages. The Journal of Immunology. 194(11). 5472–5487. 137 indexed citations

Dumas, Aline, Nathalie Amiable, Juan Pablo de Rivero Vaccari, et al.. (2014). The Inflammasome Pyrin Contributes to Pertussis Toxin-Induced IL-1β Synthesis, Neutrophil Intravascular Crawling and Autoimmune Encephalomyelitis. PLoS Pathogens. 10(5). e1004150–e1004150. 70 indexed citations

Lee, Geun‐Shik, Naeha Subramanian, Ivona Aksentijevich, et al.. (2012). The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature. 492(7427). 123–127. 840 indexed citations breakdown →

10.

Balow, James E., John Ryan, Jae Jin Chae, et al.. (2012). Microarray-based gene expression profiling in patients with cryopyrin-associated periodic syndromes defines a disease-related signature and IL-1-responsive transcripts. Annals of the Rheumatic Diseases. 72(6). 1064–1070. 21 indexed citations

11.

Booty, Matthew G., Jae Jin Chae, Seth L. Masters, et al.. (2009). Familial mediterranean fever with a single MEFV mutation: Where is the second hit?. Arthritis & Rheumatism. 60(6). 1851–1861. 183 indexed citations

12.

Chae, Jae Jin, Ivona Aksentijevich, & Daniel L. Kastner. (2009). Advances in the understanding of familial Mediterranean fever and possibilities for targeted therapy. British Journal of Haematology. 146(5). 467–478. 155 indexed citations

13.

Lamason, Rebecca L., Po Zhao, Rashmi Rawat, et al.. (2006). Sexual dimorphism in immune response genes as a function of puberty. BMC Immunology. 7(1). 2–2. 93 indexed citations

14.

Hull, Keith M., Nitza G. Shoham, Jae Jin Chae, Ivona Aksentijevich, & Daniel L. Kastner. (2003). The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations. Current Opinion in Rheumatology. 15(1). 61–69. 166 indexed citations

15.

Chae, Jae Jin, Hirsh D. Komarow, Jun Cheng, et al.. (2003). Targeted Disruption of Pyrin, the FMF Protein, Causes Heightened Sensitivity to Endotoxin and a Defect in Macrophage Apoptosis. Molecular Cell. 11(3). 591–604. 315 indexed citations

16.

Chae, Jae Jin, Michael Centola, Ivona Aksentijevich, et al.. (2000). Isolation, genomic organization, and expression analysis of the mouse and rat homologs of MEFV, the gene for familial Mediterranean fever. Mammalian Genome. 11(6). 428–435. 37 indexed citations

17.

Torosyan, Yelizaveta, Jonathan Samuels, Michael Centola, et al.. (1999). Mutation and Haplotype Studies of Familial Mediterranean Fever Reveal New Ancestral Relationships and Evidence for a High Carrier Frequency with Reduced Penetrance in the Ashkenazi Jewish Population. The American Journal of Human Genetics. 64(4). 949–962. 219 indexed citations

18.

Chae, Jae Jin, Sunghan Kim, Ki‐Hoon Han, et al.. (1999). Three novel small deletion mutations of the LDL receptor gene in Korean patients with familial hypercholesterolemia. Clinical Genetics. 55(5). 325–331. 7 indexed citations

19.

Shin, Jung Hee, et al.. (1999). Polymorphisms in the human autosomal dominant polycystic kidney disease 2 (PKD2) gene. Molecular and Cellular Probes. 13(3). 247–250. 4 indexed citations

20.

Chae, Jae Jin, et al.. (1996). A New <i>Ms</i><i>p</i>lPCR-RFLP in the Human LDL Receptor Gene. Human Heredity. 46(6). 339–341. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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