Philippe P. Roux

20.7k total citations · 8 hit papers
105 papers, 15.4k citations indexed

About

Philippe P. Roux is a scholar working on Molecular Biology, Cell Biology and Oncology. According to data from OpenAlex, Philippe P. Roux has authored 105 papers receiving a total of 15.4k indexed citations (citations by other indexed papers that have themselves been cited), including 80 papers in Molecular Biology, 20 papers in Cell Biology and 15 papers in Oncology. Recurrent topics in Philippe P. Roux's work include PI3K/AKT/mTOR signaling in cancer (32 papers), Protein Kinase Regulation and GTPase Signaling (29 papers) and Melanoma and MAPK Pathways (15 papers). Philippe P. Roux is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (32 papers), Protein Kinase Regulation and GTPase Signaling (29 papers) and Melanoma and MAPK Pathways (15 papers). Philippe P. Roux collaborates with scholars based in Canada, United States and France. Philippe P. Roux's co-authors include John Blenis, Marie Cargnello, Yves Roméo, Steven P. Gygi, Bryan A. Ballif, Ivan Topisirović, Brendan D. Manning, Andrew R. Tee, Lewis C. Cantley and Audrey Carrière and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Philippe P. Roux

102 papers receiving 15.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

2011 2.5k citations Marie Cargnello, Philippe P. Roux Microbiology and Molecular Biology Reviews profile →
ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions

2004 2.0k citations Philippe P. Roux, John Blenis Microbiology and Molecular Biology Reviews profile →
Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb

2003 949 citations Philippe P. Roux, John Blenis et al. Current Biology profile →
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

2008 646 citations Sang-Oh Yoon, Philippe P. Roux et al. profile →
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

2004 611 citations Philippe P. Roux, Bryan A. Ballif et al. profile →
RAS/ERK Signaling Promotes Site-specific Ribosomal Protein S6 Phosphorylation via RSK and Stimulates Cap-dependent Translation

2007 575 citations Philippe P. Roux, John Blenis et al. profile →
Neurotrophin signaling through the p75 neurotrophin receptor

2002 575 citations Philippe P. Roux profile →
Actin cortex architecture regulates cell surface tension

2017 290 citations Philippe P. Roux, Ewa K. Paluch et al. profile →

Peers

Countries citing papers authored by Philippe P. Roux

Since Specialization

Citations

This map shows the geographic impact of Philippe P. Roux's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philippe P. Roux with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philippe P. Roux more than expected).

Fields of papers citing papers by Philippe P. Roux

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philippe P. Roux. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philippe P. Roux. The network helps show where Philippe P. Roux may publish in the future.

Co-authorship network of co-authors of Philippe P. Roux

This figure shows the co-authorship network connecting the top 25 collaborators of Philippe P. Roux. A scholar is included among the top collaborators of Philippe P. Roux based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Philippe P. Roux. Philippe P. Roux is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	14-3-3ζ allows for adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation 2025 ·Molecular Metabolism ·(unknown), Zhipeng You, (unknown), Frédéric Paré, (unknown), (unknown), Geneviève Lavoie, Mete Civelek, Aida Martínez-Sánchez, Philippe P. Roux, Thomas M. Durcan, Gareth E. Lim	0
2	Plakoglobin regulates adipocyte differentiation independently of the Wnt/β-catenin signaling pathway 2024 ·Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·(unknown), Yves Mugabo, (unknown), (unknown), Frédéric Paré, (unknown), George A. Lavoie, Philippe P. Roux, Gareth E. Lim	1
3	The CDK12 inhibitor SR-4835 functions as a molecular glue that promotes cyclin K degradation in melanoma 2023 ·Cell Death Discovery ·Thibault Houlès, Jonathan Boucher, Geneviève Lavoie, Graham MacLeod, Sichun Lin, Stéphane Angers, Philippe P. Roux	14
4	HER2Δ16 Engages ENPP1 to Promote an Immune-Cold Microenvironment in Breast Cancer 2023 ·Cancer Immunology Research ·Sherif Samer Attalla, Jonathan Boucher, (unknown), Tarek Taifour, (unknown), Virginie Sanguin‐Gendreau, (unknown), (unknown), (unknown), (unknown), Hellen Kuasne, Vasilios Papavasiliou, Logan A. Walsh, Márk Barok, Heikki Joensuu, Morag Park, Philippe P. Roux, William J. Muller	7
5	Proteomic analysis of the actin cortex in interphase and mitosis 2022 ·Journal of Cell Science ·(unknown), Sami Nourreddine, Geneviève Lavoie, (unknown), Philippe P. Roux, Ewa K. Paluch	9
6	CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma 2022 ·Nature Communications ·Thibault Houlès, Geneviève Lavoie, Sami Nourreddine, Winnie Cheung, (unknown), (unknown), (unknown), Benoı̂t Grondin, Sichun Lin, Marc K. Saba-El-Leil, Stéphane Angers, Sylvain Meloche, Philippe P. Roux	23
7	CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells 2022 ·Blood Advances ·(unknown), Elisa Tomellini, Jalila Chagraoui, Bernhard Lehnertz, Nadine Mayotte, Marie-Ève Bordeleau, Philippe P. Roux, Guy Sauvageau	2
8	RIOK2 phosphorylation by RSK promotes synthesis of the human small ribosomal subunit 2021 ·PLoS Genetics ·(unknown), Thibault Houlès, (unknown), (unknown), (unknown), Geneviève Lavoie, (unknown), Sylvain Cantaloube, Carine Froment, Odile Burlet‐Schiltz, Yves Henry, Philippe P. Roux, Anthony K. Henras, Yves Roméo	10
9	Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation 2021 ·Cell ·Joseph Tcherkezian, Perry A. Brittis, Franziska Thomas, Philippe P. Roux, John G. Flanagan	2
10	STRIPAK regulates Slik localization to control mitotic morphogenesis and epithelial integrity 2020 ·The Journal of Cell Biology ·(unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Sébastien Lemieux, Philippe P. Roux, David R. Hipfner, Sébastien Carreno	8
11	Sustained ERK1/2 signaling is necessary for follicular rupture during ovulation in mice 2020 ·Reproduction ·(unknown), (unknown), (unknown), Vilceu Bordignon, Philippe P. Roux, Raj Duggavathi	8
12	Regulation of protein kinase Cδ Nuclear Import and Apoptosis by Mechanistic Target of Rapamycin Complex-1 2019 ·Scientific Reports ·(unknown), Alexander A. Goldberg, Ayesha Baig, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), T.M. Schmeing, Ying-Shan Han, Jeffrey Downey, Maziar Divangahi, Philippe P. Roux, Arnold S. Kristof	2
13	RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma 2018 ·Cancer Research ·Thibault Houlès, Simon‐Pierre Gravel, Geneviève Lavoie, Sejeong Shin, Mathilde Savall, (unknown), Benoı̂t Grondin, Louis Gaboury, Sang-Oh Yoon, Julie St‐Pierre, Philippe P. Roux	45
14	EPCR expression marks UM171-expanded CD34+ cord blood stem cells 2017 ·Blood ·Iman Fares, Jalila Chagraoui, Bernhard Lehnertz, Tara MacRae, Nadine Mayotte, Elisa Tomellini, Léo Aubert, Philippe P. Roux, Guy Sauvageau	132
15	Translational control by oncogenic signaling pathways 2014 ·Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms ·(unknown), Philippe P. Roux	42
16	Casein Kinase 1ϵ Promotes Cell Proliferation by Regulating mRNA Translation 2013 ·Cancer Research ·Sejeong Shin, Laura Wolgamott, Philippe P. Roux, Sang-Oh Yoon	39
17	RSK promotes G2 DNA damage checkpoint silencing and participates in melanoma chemoresistance 2012 ·Oncogene ·(unknown), Yves Roméo, (unknown), Paul Déléris, Joseph Tcherkezian, Jacob A. Galán, Philippe P. Roux	32
18	Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases breakdown → 2011 ·Microbiology and Molecular Biology Reviews ·Marie Cargnello, Philippe P. Roux	2528
19	mTOR Activity Restores Retinal Ganglion Cell Dendritic Arbors And Glutamatergic Inputs After Injury In Vivo 2011 ·Investigative Ophthalmology & Visual Science ·Barbara Morquette, Philippe P. Roux, Elena Feinstein, (unknown), Adriana Di Polo	1
20	The Tumor Suppressor DAP Kinase Is a Target of RSK-Mediated Survival Signaling 2005 ·Current Biology ·Rana Anjum, Philippe P. Roux, Bryan A. Ballif, Steven P. Gygi, John Blenis	118

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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