William J. Muller

27.4k citations

267 papers · 21.2k indexed · 4 hit papers · h-index 80

Impact in

Immunology and Allergy top 0.1%
- Cell Adhesion Molecules Research
Oncology top 0.1%
- Cancer Cells and Metastasis
- HER2/EGFR in Cancer Research
- Cancer-related Molecular Pathways

Papers in

Oncology 167
- HER2/EGFR in Cancer Research 73
- Cancer Cells and Metastasis 36
- Cancer-related Molecular Pathways 20
Immunology and Allergy 32
- Cell Adhesion Molecules Research 32

Co-authors: Robert D. Cardiff Peter M. Siegel Philip Leder Eric Sinn Paul K. Pattengale David Dankort Donald E. White Rachelle L. Dillon
Journals: Cancer Research (33 papers)Molecular and Cellular Biology (31 papers)Oncogene (29 papers)Proceedings of the National Academy of Sciences (23 papers)Journal of Biological Chemistry (10 papers)
Partner nations: Canada United States United Kingdom

In The Last Decade

William J. Muller

264 papers receiving 20.9k citations

Hit Papers

align trajectories log scale

Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer 2013 · 677 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2013 Cancer Cell
2003 American Journal Of Pathology
1988 Cell
1987 Cell

Peers

Countries citing papers authored by William J. Muller

Since Specialization

Citations

This map shows the geographic impact of William J. Muller's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William J. Muller with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William J. Muller more than expected).

Fields of papers citing papers by William J. Muller

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William J. Muller. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William J. Muller. The network helps show where William J. Muller may publish in the future.

Co-authors

The 25 scholars most cited alongside William J. Muller, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with William J. Muller Line = papers co-authored together William J. Muller links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The Multifaceted Role of Osteopontin in Modulating the Tumor Microenvironment Cancer Research ·Yu Gu, William J. Muller	2025	1
2	The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer Immunity ·Tarek Taifour, Sherif Samer Attalla, Dongmei Zuo, Yu Gu, Virginie Sanguin‐Gendreau, Hailey Proud, Emilie Solymoss, Tung Bui, Hellen Kuasne, Vasilios Papavasiliou, Chun Geun Lee, Suchitra Kamle, Peter M. Siegel, Jack A. Elias, Morag Park, William J. Muller	2023	70
3	508MO Spatial remodeling of the immune tumor microenvironment after radiotherapy and CXCL12 inhibition in glioblastoma in the phase I/II GLORIA trial Annals of Oncology ·S. Leonardelli, Julian Philipp Layer, Lea L. Friker, Roberta Turiello, Gemma van der Voort, Dillon Corvino, Christina Schaub, William J. Muller, Elena Sperk, Leonard Christopher Schmeel, Katja Sahm, Sied Kebir, Peter Hambsch, Torsten Pietsch, Kevin Thurley, Martin Glas, Clemens Seidel, Ulrich Herrlinger, Frank A. Giordano, M. Hölzel	2023	1
4	Integration of Distinct ShcA Signaling Complexes Promotes Breast Tumor Growth and Tyrosine Kinase Inhibitor Resistance Molecular Cancer Research ·Jacqueline R. Ha, Ryuhjin Ahn, Harvey W. Smith, Valérie Sabourin, Steven Hébert, Eduardo Cepeda Cañedo, Young Kyuen Im, Claudia L. Kleinman, William J. Muller, Josie Ursini‐Siegel	2018	6
5	c-Src regulates cargo transit via the Golgi in pancreatic acinar cells Scientific Reports ·Sergiy Kostenko, Chan C. Heu, Jordan R. Yaron, Garima Singh, Cristiane de Oliveira, William J. Muller, Vijay Singh	2018	5
6	ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor Oncogene ·Alexandra M. Simond, Tadimeti S. Rao, Dongmei Zuo, Jean J. Zhao, William J. Muller	2017	6
7	STAT3 Establishes an Immunosuppressive Microenvironment during the Early Stages of Breast Carcinogenesis to Promote Tumor Growth and Metastasis Cancer Research ·Laura Jones, Miranda L. Broz, Jill J. Ranger, John Ozcelik, Ryuhjin Ahn, Dongmei Zuo, Josie Ursini‐Siegel, Michael Hallett, Matthew F. Krummel, William J. Muller	2016	84
8	Ablation of miR-10b Suppresses Oncogene-Induced Mammary Tumorigenesis and Metastasis and Reactivates Tumor-Suppressive Pathways Cancer Research ·Jongchan Kim, Ashley N. Siverly, Dahu Chen, Min Wang, Yuan Yuan, Yumeng Wang, Hyemin Lee, Jinsong Zhang, William J. Muller, Han Liang, Boyi Gan, Xianbin Yang, Yutong Sun, M. James You, Li Ma	2016	78
9	Chemoprevention Activity of 25-Hydroxyvitamin D in the MMTV-PyMT Mouse Model of Breast Cancer Cancer Prevention Research ·Lionel Rossdeutscher, Jiarong Li, Aimée-Lee Luco, Ibtihal Fadhil, Benoît Ochietti, Anne Camirand, Dao Chao Huang, Timothy A. Reinhardt, William J. Muller, Richard Kremer	2014	34
10	Cancer Affects microRNA Expression, Release, and Function in Cardiac and Skeletal Muscle Cancer Research ·Daohong Chen, Chirayu Goswami, Riesa Burnett, Manjushree Anjanappa, Poornima Bhat‐Nakshatri, William J. Muller, Harikrishna Nakshatri	2014	46
11	14-3-3ζ Orchestrates Mammary Tumor Onset and Progression via miR-221–Mediated Cell Proliferation Cancer Research ·Sumaiyah K. Rehman, Shau-Hsuan Li, Shannon L. Wyszomierski, Qingfei Wang, Ping Li, Özgür Şahin, Yi Xiao, Siyuan Zhang, Yan Xiong, Jun Yang, Hai Wang, Hua Guo, Jitao David Zhang, Daniel Medina, William J. Muller, Dihua Yu	2013	23
12	HER3 Is Required for HER2-Induced Preneoplastic Changes to the Breast Epithelium and Tumor Formation Cancer Research ·David Vaught, Jamie C. Stanford, Christian D. Young, Donna J. Hicks, Frank Wheeler, Cammie Rinehart, Violeta Sánchez, John G. Koland, William J. Muller, Carlos L. Arteaga, Rebecca S. Cook	2012	104
13	The p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis Genes & Development ·Tamara Utermark, Trisha Rao, Hailing Cheng, Qi Wang, Sang‐Hyun Lee, Zhigang C. Wang, J. Dirk Iglehart, Thomas M. Roberts, William J. Muller, Jean J. Zhao	2012	112
14	Activation of Murine Double Minute 2 by Akt in Mammary Epithelium Delays Mammary Involution and Accelerates Mammary Tumorigenesis Cancer Research ·Xiaoyun Cheng, Weiya Xia, Jer-Yen Yang, Jennifer L. Hsu, Jing-Yu Lang, Chao‐Kai Chou, Yi Du, Hui-Lung Sun, Shannon L. Wyszomierski, Gordon B. Mills, William J. Muller, Dihua Yu, Mien‐Chie Hung	2010	16
15	Receptor Tyrosine Kinase Signaling Favors a Protumorigenic State in Breast Cancer Cells by Inhibiting the Adaptive Immune Response Cancer Research ·Josie Ursini‐Siegel, Sean Cory, Dongmei Zuo, W. Rod Hardy, Elton Rexhepaj, Sonya H.L. Lam, Babette Schade, Karin Jirström, Eva Bjur, Ciriaco A. Piccirillo, David G. DeNardo, Lisa M. Coussens, Donal J. Brennan, William M. Gallagher, Morag Park, Tony Pawson, Michael Hallett, William J. Muller	2010	24
16	Transcriptional Control of the ERBB2 Amplicon by ERRα and PGC-1β Promotes Mammary Gland Tumorigenesis Cancer Research ·Geneviève Deblois, Ghada Chahrour, Marie-Claude Perry, Guillaume Sylvain-Drolet, William J. Muller, Vincent Giguère	2010	73
17	Overexpression of the Protein Tyrosine Phosphatase PRL-2 Correlates with Breast Tumor Formation and Progression Cancer Research ·Serge Hardy, Nau Nau Wong, William J. Muller, Morag Park, Michel L. Tremblay	2010	54
18	The EGF/CSF-1 Paracrine Invasion Loop Can Be Triggered by Heregulin β1 and CXCL12 Cancer Research ·Lorena Hernandez, Т. А. Смирнова, Dmitriy Kedrin, Jeffrey Wyckoff, Liyin Zhu, E. Richard Stanley, Dianne Cox, William J. Muller, Jeffrey W. Pollard, Nico van Rooijen, Jeffrey E. Segall	2009	96
19	Akt1 and Akt2 Play Distinct Roles in the Initiation and Metastatic Phases of Mammary Tumor Progression Cancer Research ·Rachelle L. Dillon, Richard Marcotte, Bryan T. Hennessy, James R. Woodgett, Gordon B. Mills, William J. Muller	2009	148
20	Effect of Conditional Knockout of the Type II TGF-β Receptor Gene in Mammary Epithelia on Mammary Gland Development and Polyomavirus Middle T Antigen Induced Tumor Formation and Metastasis Cancer Research ·Elizabeth Forrester, Anna Chytil, Brian Bierie, Mary Aakre, Agnieszka E. Gorska, Ali‐Reza Sharif‐Afshar, William J. Muller, Harold L. Moses	2005	195

About William J. Muller

William J. Muller is a scholar working on Oncology, Immunology and Allergy, Radiology, Nuclear Medicine and Imaging, Molecular Biology and Immunology, having authored 267 papers that have together received 21.2k indexed citations. Recurring topics across this work include HER2/EGFR in Cancer Research (73 papers), Monoclonal and Polyclonal Antibodies Research (54 papers), PI3K/AKT/mTOR signaling in cancer (38 papers), Cancer Cells and Metastasis (36 papers), Cell Adhesion Molecules Research (32 papers), Virus-based gene therapy research (26 papers), Immunotherapy and Immune Responses (26 papers) and Cancer-related Molecular Pathways (20 papers). The work is most often cited by research in Immunology and Allergy (2.1k citations), Oncology (9.2k citations), Cancer Research (3.8k citations), Molecular Biology (13.3k citations) and Cell Biology (2.8k citations). William J. Muller has collaborated with scholars based in Canada, United States and United Kingdom. Frequent co-authors include Robert D. Cardiff, Peter M. Siegel, Philip Leder, Eric Sinn, Paul K. Pattengale, David Dankort, Donald E. White, Rachelle L. Dillon, W. Rod Hardy and John A. Hassell. Their work appears in journals such as Cancer Research, Molecular and Cellular Biology, Oncogene, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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