Robert V. Farese

48.2k citations

238 papers · 34.9k indexed · 16 hit papers · h-index 96

Impact in

Biochemistry top 0.01%
- Lipid metabolism and biosynthesis
Geriatrics and Gerontology top 0.1%

Papers in

Biochemistry 107
- Lipid metabolism and biosynthesis 106
Physiology 94
- Adipose Tissue and Metabolism 80

Co-authors: Tobias C. Walther Scot J. Stone Sylvaine Cases Rudolf Zechner Chi–Liang Eric Yen Erin Currie Hubert C. Chen Almut Schulze
Journals: Journal of Biological Chemistry (27 papers)Journal of Clinical Investigation (21 papers)Endocrinology (19 papers)Journal of Lipid Research (15 papers)Proceedings of the National Academy of Sciences (14 papers)
Partner nations: United States Germany Japan

In The Last Decade

Robert V. Farese

236 papers receiving 34.4k citations

Hit Papers

15 papers align trajectories log scale

Lipid Droplet Biogenesis 2017 · 561 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2017 Annual Review of Cell and Developmental Biology
2017 Nature Reviews Gastroenterology & Hepatology
2013 Nature Reviews Molecular Cell Biology
2013 Cell Metabolism
2013 Developmental Cell
2012 Annual Review of Biochemistry
2010 Nature
2009 Cell
2008 Journal of Lipid Research
2008 Nature
2007 Molecular and Cellular Biology
2003 Proceedings of the National Academy of Sciences
2001 Journal of Biological Chemistry
1998 Nature
1998 Proceedings of the National Academy of Sciences
1997 Journal of Clinical Investigation

Peers

Countries citing papers authored by Robert V. Farese

Since Specialization

Citations

This map shows the geographic impact of Robert V. Farese's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert V. Farese with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert V. Farese more than expected).

Fields of papers citing papers by Robert V. Farese

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert V. Farese. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert V. Farese. The network helps show where Robert V. Farese may publish in the future.

Co-authors

The 25 scholars most cited alongside Robert V. Farese, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Robert V. Farese Line = papers co-authored together Robert V. Farese links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Essential Biology of Lipid Droplets Annual Review of Biochemistry ·Robert V. Farese, Tobias C. Walther	2025	5
2	Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity eLife ·Chandramohan Chitraju, Alexander W. Fischer, Irène V. Spilka, Kun Wang, Bo Yuan, Sheng Hui, Tobias C. Walther, Robert V. Farese	2023	18
3	Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis Nature Communications ·Xuewu Sui, Kun Wang, Kangkang Song, Xu Chen, Sasa Stanojkov, Chia‐Wei Lee, Maofu Liao, Robert V. Farese, Tobias C. Walther	2023	10
4	The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification Nature Communications ·Kun Wang, Chia‐Wei Lee, Xuewu Sui, Siyoung Kim, 田代郁代, Alessio Gonnelli, 貢治渡辺, Gregory A. Voth, Maofu Liao, Tobias C. Walther, Robert V. Farese	2023	10
5	Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis Nature Communications ·Sebastian Boland, Sharan Swarup, Irène V. Spilka, Rafael E. Rodriguez, David M. Ray, Alexander W. Fischer, Shubham Singh, Geetika Aggarwal, Salvatore Spina, Alissa L. Nana, Lea T. Grinberg, William W. Seeley, Michał A. Surma, Christian Klose, João A. Paulo, Andrew D. Nguyen, J. Wade Harper, Tobias C. Walther, Robert V. Farese	2022	44
6	Seipin forms a flexible cage at lipid droplet formation sites Nature Structural & Molecular Biology ·Henning Arlt, Xuewu Sui, Christine Meinel, Carson Adams, Justin L. Perez, Beixin Shi, Fred A. Hamprecht, Frank DiMaio, Maofu Liao, Joel Goodman, Robert V. Farese, Tobias C. Walther	2022	63
7	Conditional targeting of phosphatidylserine decarboxylase to lipid droplets Biology Open ·Santosh Kumar, Chandramohan Chitraju, Robert V. Farese, Tobias C. Walther, Christopher G. Burd	2021	15
8	Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme Nature ·Xuewu Sui, Kun Wang, Nina L. Gluchowski, Shane D. Elliott, Maofu Liao, Tobias C. Walther, Robert V. Farese	2020	86
9	The FATP1–DGAT2 complex facilitates lipid droplet expansion at the ER–lipid droplet interface The Journal of Cell Biology ·Ningyi Xu, Ayhan Başçı, Duane Lenhardt, Sean McKinney, Fengli Guo, Joel T. Haas, Sudheer Bobba, Robert V. Farese, Ho Yi Mak	2012	227
10	Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects Cell Reports ·Sandra Almeida, Zhijun Zhang, Giangennaro Coppola, Wenjie Mao, Kensuke Futai, Anna Karydas, Michael D. Geschwind, Maria Carmela Tartaglia, Fuying Gao, Davide Gianni, Miguel Sena‐Esteves, Daniel H. Geschwind, Bruce L. Miller, Robert V. Farese, Fen‐Biao Gao	2012	3
11	DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation Journal of Clinical Investigation ·Suneil K. Koliwad, Ryan S. Streeper, Mara Monetti, Ivo Cornelissen, Liana C. Chan, Koji Terayama, Stephen Naylor, Meghana Rao, Brian K. Hubbard, Robert V. Farese	2010	175
12	Membrane Topology and Identification of Key Functional Amino Acid Residues of Murine Acyl-CoA:Diacylglycerol Acyltransferase-2 Journal of Biological Chemistry ·Scot J. Stone, Malin Levin, Robert V. Farese	2006	175
13	Obesity resistance and enhanced glucose metabolismin mice transplanted with white adipose tissue lackingacyl CoA:diacylglycerol acyltransferase 1 Journal of Clinical Investigation ·Hubert C. Chen, Dalan R. Jensen, Heather Myers, Robert H. Eckel, Robert V. Farese	2003	72
14	Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands Journal of Clinical Investigation ·Hubert C. Chen, Steven J. Smith, 洋三武久, Peter M. Elias, Robert V. Farese	2002	109
15	Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1 Journal of Clinical Investigation ·Hubert C. Chen, S. J. Smith, D. Morge, Dalan R. Jensen, Luis D. Ferreira, Leslie K. Pulawa, James G. McGuire, Robert E. Pitas, Robert H. Eckel, Robert V. Farese	2002	11
16	Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands Journal of Clinical Investigation ·Hubert C. Chen, S. J. Smith, 洋三武久, Peter M. Elias, Robert V. Farese	2002	4
17	Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1 Journal of Clinical Investigation ·Hubert C. Chen, Steven J. Smith, D. Morge, Dalan R. Jensen, Luis D. Ferreira, Leslie K. Pulawa, James G. McGuire, Robert E. Pitas, Robert H. Eckel, Robert V. Farese	2002	234
18	Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1 Journal of Clinical Investigation ·Michel Accad, Steven J. Smith, Dale Newland, David A. Sanan, Lloyd E. King, MacRae F. Linton, Sergio Fazio, Robert V. Farese	2000	196
19	Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet. Journal of Clinical Investigation ·Colleen Jennifer Treado, Robert V. Farese, David Johnson, L. M. Flynn, Vincenzo Pierotti, Dale Newland, MacRae F. Linton, David A. Sanan, Stephen G. Young	1995	163
20	Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a). Journal of Clinical Investigation ·MacRae F. Linton, Robert V. Farese, Giulia Chiesa, David Grass, P Chin, Robert E. Hammer, Helen H. Hobbs, Stephen G. Young	1993	201

About Robert V. Farese

Robert V. Farese is a scholar working on Biochemistry, Physiology, Cell Biology, Endocrinology, Diabetes and Metabolism and Molecular Biology, having authored 238 papers that have together received 34.9k indexed citations. Recurring topics across this work include Lipid metabolism and biosynthesis (106 papers), Adipose Tissue and Metabolism (80 papers), Pancreatic function and diabetes (47 papers), Peroxisome Proliferator-Activated Receptors (29 papers), Metabolism, Diabetes, and Cancer (24 papers), Endoplasmic Reticulum Stress and Disease (24 papers), Photosynthetic Processes and Mechanisms (22 papers) and Cholesterol and Lipid Metabolism (18 papers). The work is most often cited by research in Biochemistry (13.5k citations), Geriatrics and Gerontology (1.6k citations), Physiology (8.4k citations), Cell Biology (4.5k citations) and Molecular Biology (17.9k citations). Robert V. Farese has collaborated with scholars based in United States, Germany and Japan. Frequent co-authors include Tobias C. Walther, Scot J. Stone, Sylvaine Cases, Rudolf Zechner, Chi–Liang Eric Yen, Erin Currie, Hubert C. Chen, Almut Schulze, Charles Harris and Abdou Rachid Thiam. Their work appears in journals such as Journal of Biological Chemistry, Journal of Clinical Investigation, Endocrinology, Journal of Lipid Research and Proceedings of the National Academy of Sciences.

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