Günter Blobel

55.6k citations

295 papers · 46.2k indexed · 46 hit papers · h-index 116

Molecular Biology top 0.01%
Cell Biology top 0.02%
Genetics top 0.05%
Immunology top 0.5%
Plant Science top 0.5%

Co-authors: Peter Walter B Dobberstein Van R. Potter Mary Shannon Moore Larry Gerace Michael P. Rout M. Gerard Waters Reid Gilmore
Topics: RNA Research and Splicing (113 papers)Nuclear Structure and Function (110 papers)RNA and protein synthesis mechanisms (86 papers)
Cited by: Molecular Biology Cell Biology Genetics
Journals: Nature Science Cell
Partner nations: United States Germany Canada

In The Last Decade

Günter Blobel

295 papers receiving 43.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 2.5k citations Günter Blobel et al. The Journal of Cell Biology profile →
Nuclei from Rat Liver: Isolation Method That Combines Purity with High Yield

1966 1.5k citations Günter Blobel et al. profile →
Intracellular protein topogenesis

1980 1.1k citations Günter Blobel Proceedings of the National Academy of Sciences profile →
70K heat shock related proteins stimulate protein translocation into microsomes

1988 1.1k citations Günter Blobel et al. profile →
Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components.

1975 937 citations Günter Blobel et al. The Journal of Cell Biology profile →
The nuclear envelope lamina is reversibly depolymerized during mitosis

1980 813 citations Günter Blobel et al. Cell profile →
Protein translocation across the endoplasmic reticulum

1984 705 citations Günter Blobel et al. Cell profile →
Crystallographic Analysis of the Recognition of a Nuclear Localization Signal by the Nuclear Import Factor Karyopherin α

1998 674 citations Günter Blobel et al. Cell profile →
The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1993 672 citations Günter Blobel et al. profile →
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins

1995 670 citations Michael Rexach, Günter Blobel Cell profile →
Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes.

1981 638 citations Günter Blobel et al. The Journal of Cell Biology profile →
cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins.

1986 616 citations Nilabh Chaudhary, Günter Blobel et al. Proceedings of the National Academy of Sciences profile →
[6] Preparation of microsomal membranes for cotranslational protein translocation

1983 615 citations Günter Blobel et al. Methods in enzymology on CD-ROM/Methods in enzymology profile →
Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum

1982 604 citations Günter Blobel et al. profile →
Identification and characterization of a nuclear pore complex protein

1986 542 citations Günter Blobel et al. Cell profile →
Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in-vitro-assembled polysomes synthesizing secretory protein.

1981 527 citations Günter Blobel et al. The Journal of Cell Biology profile →
A protein-conducting channel in the endoplasmic reticulum

1991 496 citations Günter Blobel et al. Cell profile →
Immunocytochemical localization of the major polypeptides of the nuclear pore complex-lamina fraction. Interphase and mitotic distribution.

1978 474 citations Günter Blobel et al. The Journal of Cell Biology profile →
Nup358, a Cytoplasmically Exposed Nucleoporin with Peptide Repeats, Ran-GTP Binding Sites, Zinc Fingers, a Cyclophilin A Homologous Domain, and a Leucine-rich Region

1995 412 citations Günter Blobel, Elias Coutavas et al. Journal of Biological Chemistry profile →
Ubc9p Is the Conjugating Enzyme for the Ubiquitin-like Protein Smt3p

1997 412 citations Günter Blobel et al. Journal of Biological Chemistry profile →
The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains

1984 406 citations Günter Blobel et al. profile →
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex

1995 405 citations Günter Blobel et al. Cell profile →
Structure of the 80S Ribosome from Saccharomyces cerevisiae—tRNA-Ribosome and Subunit-Subunit Interactions

2001 402 citations Günter Blobel et al. Cell profile →
SUMO-1 Modification and Its Role in Targeting the Ran GTPase-activating Protein, RanGAP1, to the Nuclear Pore Complex

1998 401 citations Günter Blobel et al. The Journal of Cell Biology profile →
Studies on free and membrane-bound ribosomes in rat liver

1967 396 citations Günter Blobel et al. profile →
Dissociation of Mammalian Polyribosomes into Subunits by Puromycin

1971 389 citations Günter Blobel et al. Proceedings of the National Academy of Sciences profile →
Nopp 140 shuttles on tracks between nucleolus and cytoplasm

1992 350 citations Günter Blobel et al. Cell profile →
Translocation of proteins across the endoplasmic reticulum. II. Signal recognition protein (SRP) mediates the selective binding to microsomal membranes of in-vitro-assembled polysomes synthesizing secretory protein.

1981 341 citations Günter Blobel et al. The Journal of Cell Biology profile →
Isolation of Components of the Chloroplast Protein Import Machinery

1994 331 citations Günter Blobel et al. profile →
A lamin B receptor in the nuclear envelope.

1988 318 citations Günter Blobel et al. Proceedings of the National Academy of Sciences profile →
Membrane assembly in vitro : Synthesis, glycosylatio, and asymmetric insertion of a transmembrane protein

1977 311 citations Günter Blobel et al. Proceedings of the National Academy of Sciences profile →
Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle.

1982 310 citations Günter Blobel et al. The Journal of Cell Biology profile →
Isolation of nuclear pore complexes in association with a lamina.

1975 308 citations Günter Blobel et al. Proceedings of the National Academy of Sciences profile →
Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathway.

1987 290 citations Günter Blobel et al. Proceedings of the National Academy of Sciences profile →
[8] Immunoprecipitation of proteins from cell-free translations

1983 286 citations Günter Blobel et al. Methods in enzymology on CD-ROM/Methods in enzymology profile →
A Protein of Molecular Weight 78,000 Bound to the Polyadenylate Region of Eukaryotic Messenger RNAs

1973 286 citations Günter Blobel Proceedings of the National Academy of Sciences profile →
RIBOSOME-MEMBRANE INTERACTION

1973 276 citations Günter Blobel et al. The Journal of Cell Biology profile →
[3] Cell-free translation of messenger RNA in a wheat germ system

1983 270 citations Günter Blobel et al. Methods in enzymology on CD-ROM/Methods in enzymology profile →
Secretory protein translocation in a yeast cell-free system can occur posttranslationally and requires ATP hydrolysis.

1986 262 citations Günter Blobel et al. The Journal of Cell Biology profile →
CONTROLLED PROTEOLYSIS OF NASCENT POLYPEPTIDES IN RAT LIVER CELL FRACTIONS

1970 256 citations Günter Blobel et al. The Journal of Cell Biology profile →
Biogenesis of peroxisomes: intracellular site of synthesis of catalase and uricase.

1978 235 citations Günter Blobel et al. Proceedings of the National Academy of Sciences profile →
Homology in amino-terminal sequence of precursors to pancreatic secretory proteins.

1975 220 citations Günter Blobel et al. Proceedings of the National Academy of Sciences profile →
A signal sequence for the insertion of a transmembrane glycoprotein. Similarities to the signals of secretory proteins in primary structure and function.

1978 219 citations Günter Blobel et al. Journal of Biological Chemistry profile →
Post-translational cleavage of presecretory proteins with an extract of rough microsomes from dog pancreas containing signal peptidase activity.

1977 215 citations Günter Blobel et al. Proceedings of the National Academy of Sciences profile →
Efficient cleavage and segregation of nascent presecretory proteins in a reticulocyte lysate supplemented with microsomal membranes.

1978 197 citations Günter Blobel et al. Journal of Biological Chemistry profile →
Nascent prehormones are intermediates in the biosynthesis of authentic bovine pituitary growth hormone and prolactin.

1977 174 citations Günter Blobel et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by Günter Blobel

Since Specialization

Citations

This map shows the geographic impact of Günter Blobel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Günter Blobel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Günter Blobel more than expected).

Fields of papers citing papers by Günter Blobel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Günter Blobel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Günter Blobel. The network helps show where Günter Blobel may publish in the future.

Co-authorship network of co-authors of Günter Blobel

This figure shows the co-authorship network connecting the top 25 collaborators of Günter Blobel. A scholar is included among the top collaborators of Günter Blobel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Günter Blobel. Günter Blobel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport 2017 ·Proceedings of the National Academy of Sciences ·Xiaochun Li,Feiran Lu,Michael Trinh,Philip Schmiege,Joachim Seemann,Jiawei Wang,Günter Blobel	76
2	Structure of human Niemann–Pick C1 protein 2016 ·Proceedings of the National Academy of Sciences ·Xiaochun Li,Jiawei Wang,Elias Coutavas,Hang Shi,Qi Hao,Günter Blobel	129
3	Clues to the mechanism of cholesterol transfer from the structure of NPC1 middle lumenal domain bound to NPC2 2016 ·Proceedings of the National Academy of Sciences ·Xiaochun Li,Piyali Saha,Jian Li,Günter Blobel,Suzanne R. Pfeffer	132
4	Three-dimensional structure and flexibility of a membrane-coating module of the nuclear pore complex 2009 ·Nature Structural & Molecular Biology ·Martin Kampmann,Günter Blobel	93
5	A Fence-like Coat for the Nuclear Pore Membrane 2008 ·Molecular Cell ·Erik Debler,Yingli Ma,Hyuk‐Soo Seo,Kuo‐Chiang Hsia,Thomas R. Noriega,Günter Blobel,André Hoelz	102
6	Architecture of a Coat for the Nuclear Pore Membrane 2007 ·Cell ·Kuo‐Chiang Hsia,Pete Stavropoulos,Günter Blobel,André Hoelz	112
7	Homodimerization of the G protein SRβ in the nucleotide-free state involves proline cis/trans isomerization in the switch II region 2006 ·Proceedings of the National Academy of Sciences ·Thomas Schwartz,Daniel Schmidt,Stephen G. Brohawn,Günter Blobel	20
8	A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization 2005 ·Proceedings of the National Academy of Sciences ·Xiaolan Zhao,Günter Blobel	358
9	Carrier-independent Nuclear Import of the Transcription Factor PU.1 via RanGTP-stimulated Binding to Nup153 2005 ·Journal of Biological Chemistry ·Hualin Zhong,Akiko Takeda,Reza Nazari,H Shio,Günter Blobel,Nabeel R. Yaseen	36
10	Structural Basis for the Function of the β Subunit of the Eukaryotic Signal Recognition Particle Receptor 2003 ·Cell ·Thomas Schwartz,Günter Blobel	78
11	Polymerization of a single protein of the pathogen Yersinia enterocolitica into needles punctures eukaryotic cells 2001 ·Proceedings of the National Academy of Sciences ·Egbert Hoiczyk,Günter Blobel	143
12	Nuclear Import of Spo12p, a Protein Essential for Meiosis 2001 ·Journal of Biological Chemistry ·Susana R. Chaves,Günter Blobel	23
13	Protein Targeting (Nobel Lecture) 2000 ·ChemBioChem ·Günter Blobel	8
14	Protein Targeting (Nobel Lecture) 2000 ·ChemBioChem ·Günter Blobel	108
15	Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporinsbreakdown → 1995 ·Cell ·Michael Rexach,Günter Blobel	670
16	NUP145 encodes a novel yeast glycine-leucine-phenylalanine-glycine (GLFG) nucleoporin required for nuclear envelope structure. 1994 ·The Journal of Cell Biology ·Susan R. Wente,Günter Blobel	123
17	A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm 1993 ·Cell ·Jun Sukegawa,Günter Blobel	270
18	Lamin B autoantibodies in sera of certain patients with systemic lupus erythematosus. 1987 ·The Journal of Experimental Medicine ·Westley H. Reeves,Nilabh Chaudhary,A Salerno,Günter Blobel	68
19	[52] Control of intracellular protein traffic 1983 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Günter Blobel	13
20	Protein antigens of the RNA-protein complexes detected by anti-SM and anti-RNP antibodies found in serum of patients with systemic lupus erythematosus and related disorders. 1982 ·The Journal of Experimental Medicine ·G E Conner,D. S. Nelson,Rosanne Wisniewolski,R G Lahita,Günter Blobel,Henry G. Kunkel	67

About Günter Blobel

Günter Blobel is a scholar working on Molecular Biology, Cell Biology and Biochemistry, having authored 295 papers that have together received 46.2k indexed citations. Recurring topics across this work include RNA Research and Splicing (113 papers), Nuclear Structure and Function (110 papers) and RNA and protein synthesis mechanisms (86 papers). The work is most often cited by research in Molecular Biology (39.0k citations), Cell Biology (8.2k citations) and Genetics (6.4k citations). Günter Blobel has collaborated with scholars based in United States, Germany and Canada. Frequent co-authors include Peter Walter, B Dobberstein, Van R. Potter, Mary Shannon Moore, Larry Gerace, Michael P. Rout, M. Gerard Waters, Reid Gilmore, Michael Rexach and Laura I. Davis. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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