Pamela J. Shaw

53.6k citations

486 papers · 29.4k indexed · 9 hit papers · h-index 89

Neurology top 0.01%
- Amyotrophic Lateral Sclerosis Research 303
- Parkinson's Disease Mechanisms and Treatments 90
- Neurological diseases and metabolism 57
- Neuroinflammation and Neurodegeneration Mechanisms 25
Genetics top 0.02%
- Neurogenetic and Muscular Disorders Research 166
Neurology top 0.05%
- Amyotrophic Lateral Sclerosis Research 303
- Parkinson's Disease Mechanisms and Treatments 90
- Neurological diseases and metabolism 57
- Neuroinflammation and Neurodegeneration Mechanisms 25
Cellular and Molecular Neuroscience top 0.1%
- Neuroscience and Neuropharmacology Research 30
Developmental Neuroscience top 0.5%
Physiology
- Alzheimer's disease research and treatments 33
Pharmacology
- Cholinesterase and Neurodegenerative Diseases 23

Co-authors: Paul G. Ince Janine Kirby Paul R. Heath Siân C. Barber Christopher McDermott Stephen B. Wharton Laura Ferraiuolo Andrew J. Grierson
Cited by: Neurology Genetics
Journals: Proceedings of the National Academy of Sciences (2 papers)The Lancet (3 papers)Journal of Biological Chemistry (1 paper)
Partner nations: United Kingdom United States Germany

In The Last Decade

Pamela J. Shaw

481 papers receiving 28.8k citations

Hit Papers

9 papers align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2022 Nature Reviews Drug Discovery
2022 The Lancet
2017 Neuroscience Letters
2017 Nature Reviews Disease Primers
2016 The EMBO Journal
2011 Nature Reviews Neurology
2009 Free Radical Biology and Medicine
2007 Annals of Neurology
2006 The Lancet Neurology

Peers

Countries citing papers authored by Pamela J. Shaw

Since Specialization

Citations

This map shows the geographic impact of Pamela J. Shaw's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Pamela J. Shaw with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Pamela J. Shaw more than expected).

Fields of papers citing papers by Pamela J. Shaw

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Pamela J. Shaw. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Pamela J. Shaw. The network helps show where Pamela J. Shaw may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Pamela J. Shaw, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Pamela J. Shaw Line = papers co-authored together Pamela J. Shaw links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Extreme exercise in males is linked to mTOR signalling and onset of amyotrophic lateral sclerosis Brain ·David O’Brien,Elham Alhathli,Ceryl A. Harwood,Debarati Bhattacharya,Kriti Gupta,Thomas Julian,Marcel Weinreich,Ryan J. H. West,Dennis Wang,Ross P. Byrne,Russell L. McLaughlin,Joanne Wuu,Michael Benatar,Johnathan Cooper‐Knock,Pamela J. Shaw	2025	2
2	A systematic review of immunosuppressive protocols used in AAV gene therapy for monogenic disorders Molecular Therapy ·Besarte Vrellaku,I. S. M. Hassan,Rebecca Howitt,Christopher P Webster,Eli Harriss,Fraser McBlane,Corinne Betts,Jorge Schettini,Mattia Lion,John E. Mindur,M. Duerr,Pamela J. Shaw,Janine Kirby,Mimoun Azzouz,Laurent Servais	2024	24
3	Physical Activity as a Risk Factor for Amyotrophic Lateral Sclerosis Neurology ·Pamela J. Shaw,Johnathan Cooper‐Knock	2024	1
4	RAN Translation of C9orf72‐Related Dipeptide Repeat Proteins in Zebrafish Recapitulates Hallmarks of Amyotrophic Lateral Sclerosis and Identifies Hypothermia as a Therapeutic Strategy Annals of Neurology ·David Burrows,Alexander McGown,Olfat Abduljabbar,Lydia M. Castelli,Pamela J. Shaw,Guillaume M. Hautbergue,Tennore Ramesh	2024	0
5	Janus kinase inhibitors are potential therapeutics for amyotrophic lateral sclerosis Translational Neurodegeneration ·Peter J. Richardson,Daniel P. Smith,Alex de Giorgio,Xenia Snetkov,Joshua Almond-Thynne,Shane Cronin,Richard J. Mead,Christopher McDermott,Pamela J. Shaw	2023	15
6	Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translationbreakdown → Nature Reviews Drug Discovery ·Richard J. Mead,Ning Shan,H. Joseph Reiser,Fiona H. Marshall,Pamela J. Shaw	2022	248
7	Comparison Of King’s Clinical Staging In Multinational Amyotrophic Lateral Sclerosis Cohorts Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration ·Rubika Balendra,Ashley Jones,Ahmad Al Khleifat,Theresa Chiwera,Paul Wicks,Carolyn Young,Pamela J. Shaw,Martin R. Turner,P. Nigel Leigh,Ammar Al‐Chalabi	2022	2
8	EphA4 targeting agents protect motor neurons from cell death induced by amyotrophic lateral sclerosis -astrocytes iScience ·Cassandra N. Dennys,Carlo Baggio,Rochelle Rodrigo,Florence Roussel,Anna Kulinich,Sarah Heintzman,Ashley Fox,Stephen J. Kolb,Pamela J. Shaw,Iryna M. Ethell,Maurizio Pellecchia,Kathrin Meyer	2022	6
9	Type 2 diabetes mellitus-associated transcriptome alterations in cortical neurones and associated neurovascular unit cells in the ageing brain Acta Neuropathologica Communications ·(unknown),Joanna J. Bury,Annabelle Chambers,Paul R. Heath,Paul G. Ince,Pamela J. Shaw,Fiona E. Matthews,Carol Brayne,Julie E. Simpson,Stephen B. Wharton	2021	32
10	SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export: genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis Molecular Neurodegeneration ·Lydia M. Castelli,Luisa Cutillo,Cleide Dos Santos Souza,Álvaro Sánchez-Martínez,Ilaria Granata,Ya-Hui Lin,Monika A. Myszczynska,Paul R. Heath,Matthew R. Livesey,Ke Ning,Mimoun Azzouz,Pamela J. Shaw,Mario Rosario Guarracino,Alexander J. Whitworth,Laura Ferraiuolo,Marta Milo,Guillaume M. Hautbergue	2021	16
11	Physical exercise is a risk factor for amyotrophic lateral sclerosis: Convergent evidence from Mendelian randomisation, transcriptomics and risk genotypes EBioMedicine ·Thomas Julian,Nicholas Glascow,Adrian Barry,Tobias Moll,Calum Harvey,Yann C. Klimentidis,Michelle Newell,Sai Zhang,M Snyder,Johnathan Cooper‐Knock,Pamela J. Shaw	2021	84
12	Advanced Glycation End Product Formation in Human Cerebral Cortex Increases With Alzheimer-Type Neuropathologic Changes but Is Not Independently Associated With Dementia in a Population-Derived Aging Brain Cohort Journal of Neuropathology & Experimental Neurology ·Annabelle Chambers,Joanna J. Bury,Thaı́s Minett,Connor D. Richardson,Carol Brayne,Paul G. Ince,Pamela J. Shaw,Claire J. Garwood,Paul R. Heath,Julie E. Simpson,Fiona E. Matthews,Stephen B. Wharton	2020	11
13	Cross-reactive probes on Illumina DNA methylation arrays: a large study on ALS shows that a cautionary approach is warranted in interpreting epigenome-wide association studies NAR Genomics and Bioinformatics ·Paul J. Hop,Ramona A. J. Zwamborn,Eilís Hannon,Annelot M. Dekker,Kristel R. van Eijk,Emma Walker,Alfredo Iacoangeli,Ashley Jones,Aleksey Shatunov,Ahmad Al Khleifat,Sarah Opie-Martin,Christopher E. Shaw,Karen Morrison,Pamela J. Shaw,Russell L. McLaughlin,Orla Hardiman,Ammar Al‐Chalabi,Leonard H. van den Berg,Jonathan Mill,Jan H. Veldink	2020	15
14	Combined fused in sarcoma‐positive (FUS+) basophilic inclusion body disease and atypical tauopathy presenting with an amyotrophic lateral sclerosis/motor neurone disease (ALS/MND)‐plus phenotype Neuropathology and Applied Neurobiology ·Stephen B. Wharton,Nick Verber,Bart Wagner,J. Robin Highley,Daniel J. Fillingham,Rachel Waller,Kate Strand,Paul G. Ince,Pamela J. Shaw	2019	6
15	Striking phenotypic variation in a family with the P506S UBQLN2 mutation including amyotrophic lateral sclerosis, spastic paraplegia, and frontotemporal dementia Neurobiology of Aging ·Soragia Athina Gkazi,Claire Troakes,Simon Topp,Jack W. Miller,Caroline Vance,Jemeen Sreedharan,Ammar Al‐Chalabi,Janine Kirby,Pamela J. Shaw,Safa Al‐Sarraj,Andrew King,Bradley Smith,Christopher E. Shaw	2018	15
16	Younger age of onset in familial amyotrophic lateral sclerosis is a result of pathogenic gene variants, rather than ascertainment bias Journal of Neurology Neurosurgery & Psychiatry ·Puja R. Mehta,Ashley Jones,Sarah Opie-Martin,Aleksey Shatunov,Alfredo Iacoangeli,Ahmad Al Khleifat,Bradley Smith,Simon Topp,Karen Morrison,Pamela J. Shaw,Christopher E. Shaw,Sarah Morgan,Alan Pittman,Ammar Al‐Chalabi	2018	29
17	The C9orf72 protein interacts with Rab1a and the ULK 1 complex to regulate initiation of autophagybreakdown → The EMBO Journal ·Christopher P Webster,Emma F. Smith,Claudia S. Bauer,Annekathrin Möller,Guillaume M. Hautbergue,Laura Ferraiuolo,Monika A. Myszczynska,Adrian Higginbottom,Matthew J. Walsh,Alexander J. Whitworth,Brian K. Kaspar,Kathrin Meyer,Pamela J. Shaw,Andrew J. Grierson,Kurt J. De Vos	2016	301
18	Neurodegeneration caused by intronic expansions of C9ORF72 is a clinically heterogeneous but pathologically distinct disease The Lancet ·Johnathan Cooper‐Knock,J. Robin Highley,Judith Hartley,Antonio Milano,Stephen Sawcer,Alistair Compston,Antonina Frolov,Gavin Charlesworth,Nicholas Wood,Oliver Bandmann,Christopher McDermott,Janine Kirby,Paul G. Ince,Pamela J. Shaw	2013	1
19	Gastrostomy use in motor neurone disease (MND): A review, meta-analysis and survey of current practice Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration ·Theocharis Stavroulakis,Theresa Walsh,Pamela J. Shaw,Christopher McDermott,(unknown)	2012	55
20	Molecular biology of colon cancer (review). PubMed ·Pamela J. Shaw,J Costa	1989	7

About Pamela J. Shaw

Pamela J. Shaw is a scholar working on Neurology, Genetics and Neurology, having authored 486 papers that have together received 29.4k indexed citations. Recurring topics across this work include Amyotrophic Lateral Sclerosis Research (303 papers), Neurogenetic and Muscular Disorders Research (166 papers), Parkinson's Disease Mechanisms and Treatments (90 papers), Neurological diseases and metabolism (57 papers), Alzheimer's disease research and treatments (33 papers), Neuroscience and Neuropharmacology Research (30 papers), Neuroinflammation and Neurodegeneration Mechanisms (25 papers) and Cholinesterase and Neurodegenerative Diseases (23 papers). The work is most often cited by research in Neurology (16.6k citations), Genetics (8.9k citations) and Neurology (5.1k citations). Pamela J. Shaw has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Paul G. Ince, Janine Kirby, Paul R. Heath, Siân C. Barber, Christopher McDermott, Stephen B. Wharton, Laura Ferraiuolo, Andrew J. Grierson, Richard J. Mead and Timothy L. Williams. Their work appears in journals such as Proceedings of the National Academy of Sciences, The Lancet and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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