Stanley H. Appel

42.9k total citations · 8 hit papers
340 papers, 30.3k citations indexed

About

Stanley H. Appel is a scholar working on Neurology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Stanley H. Appel has authored 340 papers receiving a total of 30.3k indexed citations (citations by other indexed papers that have themselves been cited), including 191 papers in Neurology, 110 papers in Molecular Biology and 83 papers in Cellular and Molecular Neuroscience. Recurrent topics in Stanley H. Appel's work include Amyotrophic Lateral Sclerosis Research (150 papers), Neuroinflammation and Neurodegeneration Mechanisms (61 papers) and Parkinson's Disease Mechanisms and Treatments (61 papers). Stanley H. Appel is often cited by papers focused on Amyotrophic Lateral Sclerosis Research (150 papers), Neuroinflammation and Neurodegeneration Mechanisms (61 papers) and Parkinson's Disease Mechanisms and Treatments (61 papers). Stanley H. Appel collaborates with scholars based in United States, Hungary and Canada. Stanley H. Appel's co-authors include David R. Beers, Jenny S. Henkel, David M. Eisenberg, Ronald C. Kessler, Roger B. Davis, Susan L. Ettner, Weihua Zhao, R G Smith, Richard L. Sidman and Allen D. Roses and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Stanley H. Appel

338 papers receiving 28.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Trends in Alternative Medicine Use in the United States, 1990-1997

1998 5.3k citations Stanley H. Appel et al. profile →
Prevalence and patterns of cognitive impairment in sporadic ALS

2005 638 citations Stanley H. Appel, Paul E. Schulz et al. Neurology profile →
Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

2006 582 citations David R. Beers, Jenny S. Henkel et al. profile →
Natural history of amyotrophic lateral sclerosis in a database population Validation of a scoring system and a model for survival prediction

1995 561 citations Stanley H. Appel et al. Brain profile →
A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and alzheimer disease

1981 527 citations Stanley H. Appel Annals of Neurology profile →
Mutant Mice (Quaking and Jimpy) with Deficient Myelination in the Central Nervous System

1964 514 citations Stanley H. Appel et al. profile →
An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study

2013 492 citations Timothy M. Miller, Alan Pestronk et al. profile →
Catalog of the Neurological Mutants of the Mouse

1965 425 citations Stanley H. Appel et al. profile →

Peers

Countries citing papers authored by Stanley H. Appel

Since Specialization

Citations

This map shows the geographic impact of Stanley H. Appel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stanley H. Appel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stanley H. Appel more than expected).

Fields of papers citing papers by Stanley H. Appel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stanley H. Appel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stanley H. Appel. The network helps show where Stanley H. Appel may publish in the future.

Co-authorship network of co-authors of Stanley H. Appel

This figure shows the co-authorship network connecting the top 25 collaborators of Stanley H. Appel. A scholar is included among the top collaborators of Stanley H. Appel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stanley H. Appel. Stanley H. Appel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Peripheral monocyte transcriptional signatures of inflammation and oxidative stress in Parkinson’s disease 2025 ·Frontiers in Immunology ·Aaron D. Thome, Jinghong Wang, Farah Atassi, Jason R. Thonhoff, Alireza Faridar, Weihua Zhao, David R. Beers, Eugene C. Lai, Stanley H. Appel	0
2	Safety and tolerability of tegoprubart in patients with amyotrophic lateral sclerosis: A Phase 2A clinical trial 2024 ·PLoS Medicine ·Steven Perrin, Shafeeq Ladha, Nicholas J. Maragakis, Michael H. Rivner, Jonathan Katz, Angela Genge, Nicholas Olney, Dale J. Lange, Daragh Heitzman, Cynthia Bodkin, Omar Jawdat, Namita Goyal, Jeffrey D. Bornstein, Carmen Mak, Stanley H. Appel, Sabrina Paganoni	2
3	Neuroinflammation is highest in areas of disease progression in semantic dementia 2021 ·Brain ·Belén Pascual, (unknown), Paolo Zanotti‐Fregonara, Matthew D. Cykowski, Mattia Veronese, (unknown), (unknown), Meixiang Yu, Mohammad Obadah Nakawah, Gustavo C. Román, Paul E. Schulz, Anithachristy S. Arumanayagam, David R. Beers, Alireza Faridar, Masahiro Fujita, Stanley H. Appel, Joseph C. Masdeu	29
4	Multimodal ¹⁸F-AV-1451 and MRI Findings in Nonfluent Variant of Primary Progressive Aphasia: Possible Insights on Nodal Propagation of Tau Protein Across the Syntactic Network 2019 ·Journal of Nuclear Medicine ·Belén Pascual, (unknown), Paolo Zanotti‐Fregonara, (unknown), (unknown), Meixiang Yu, Bryan Spann, Gustavo C. Román, Paul E. Schulz, Christof Karmonik, Stanley H. Appel, Joseph C. Masdeu	6
5	Introduction to supplement: the current status of treatment for ALS 2017 ·Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration ·Robert G. Miller, Stanley H. Appel	16
6	A Phase 1 Study Assessing the Infusion of Expanded Autologous Regulatory T Lymphocytes in Subjects with Amyotrophic Lateral Sclerosis (P3.137) 2017 ·Neurology ·Jason R. Thonhoff, David R. Beers, Weihua Zhao, (unknown), (unknown), James D. Berry, Merit Cudkowicz, Elizabeth J. Shpall, Katayoun Rezvani, Stanley H. Appel	1
7	The TREM2 Variant p.R47H is a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis (I5-2.002) 2014 ·Neurology ·Matthew Harms, Janet Cady, Erica Koval, Bruno A. Benítez, Craig M. Zaidman, Jennifer Jockel‐Balsarotti, Peggy Allred, Robert H. Baloh, John Ravits, Ericka Simpson, Stanley H. Appel, Alan Pestronk, Alison Goate, Timothy M. Miller, Carlos Cruchaga	1
8	Alzheimer Research Forum Live Discussion: Mice on Trial? Issues in the Design of Drug Studies 2009 ·Journal of Alzheimer s Disease ·Stanley H. Appel, Anatoly Chernyshev, (unknown), Patrizia Fanara, Jennifer R. Gatchel, Brian H. Johnstone, (unknown), Yun Li, (unknown), (unknown), Steve Perrin, Sean Scott, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown)	1
9	Immunotherapy for neurological diseases 2008 ·Clinical Immunology ·Pablo Villoslada, Beatriz Moreno, Ignacio Melero, José L. Pablos, Gianvito Martino, Antonio Uccelli, Xavier Montalbán, Jesús Ávila, Serge Rivest, Laia Acarín, Stanley H. Appel, Samia J. Khoury, Patrick L. McGeer, Isidró Ferrer, Mario Delgado, José Á. Obeso, Michal Schwartz	43
10	Protective effects of an anti‐inflammatory cytokine, interleukin‐4, on motoneuron toxicity induced by activated microglia 2006 ·Journal of Neurochemistry ·Weihua Zhao, Wenjie Xie, Qin Xiao, David R. Beers, Stanley H. Appel	126
11	Sublethal dose of 4-hydroxynonenal reduces intracellular calcium in surviving motor neurons in vivo 2005 ·Acta Neuropathologica ·(unknown), R G Smith, Judit Soós, József I. Engelhardt, Stanley H. Appel, László Siklós	12
12	Activated Microglia Initiate Motor Neuron Injury by a Nitric Oxide and Glutamate-Mediated Mechanism 2004 ·Journal of Neuropathology & Experimental Neurology ·Weihua Zhao, Wenjie Xie, Weidong Le, David R. Beers, Yi He, Jenny S. Henkel, Ericka P. Simpson, Albert Yen, Qin Xiao, Stanley H. Appel	136
13	Role of Potassium Channels in Amyloid‐Induced Cell Death 1998 ·Journal of Neurochemistry ·Luis V. Colom, María L. Bellido, David R. Beers, Alan Neely, Wenjie Xie, Stanley H. Appel	138
14	Ultrastructural evidence for altered calcium in motor nerve terminals in amyotrophc lateral sclerosis 1996 ·Annals of Neurology ·László Siklós, József I. Engelhardt, Yadollah Harati, R G Smith, Ferenc Joó, Stanley H. Appel	246
15	Autoimmunity as an etiological factor in sporadic amyotrophic lateral sclerosis. 1995 ·PubMed ·Stanley H. Appel, (unknown), M Alexianu, J. Engelhardt, Enrico Stefani	19
16	Evidence for autoimmunity in amyotrophic lateral sclerosis 1994 ·Journal of the Neurological Sciences ·Stanley H. Appel, R G Smith, József I. Engelhardt, Enrico Stefani	44
17	Cyclophosphamide alters the clinical and pathological expression of experimental autoimmune gray matter disease 1991 ·Journal of Neuroimmunology ·János Tajti, Enrico Stefani, Stanley H. Appel	12
18	Motor neuron reactivity of sera from animals with autoimmune models of motor neuron destruction 1990 ·Journal of the Neurological Sciences ·József I. Engelhardt, Stanley H. Appel	12
19	Increased MEPP frequency as an early sign of experimental immune‐mediated motoneuron disease 1990 ·Annals of Neurology ·Jesús Garcı́a, József I. Engelhardt, Stanley H. Appel, Enrico Stefani	16
20	Scientific approaches to clinical neurology 1977 ·Eli S. Goldensohn, Stanley H. Appel	33

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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