J. William Langston

34.9k total citations · 7 hit papers
268 papers, 24.4k citations indexed

About

J. William Langston is a scholar working on Neurology, Cellular and Molecular Neuroscience and Genetics. According to data from OpenAlex, J. William Langston has authored 268 papers receiving a total of 24.4k indexed citations (citations by other indexed papers that have themselves been cited), including 158 papers in Neurology, 90 papers in Cellular and Molecular Neuroscience and 55 papers in Genetics. Recurrent topics in J. William Langston's work include Parkinson's Disease Mechanisms and Treatments (129 papers), Neurological disorders and treatments (56 papers) and Glioma Diagnosis and Treatment (41 papers). J. William Langston is often cited by papers focused on Parkinson's Disease Mechanisms and Treatments (129 papers), Neurological disorders and treatments (56 papers) and Glioma Diagnosis and Treatment (41 papers). J. William Langston collaborates with scholars based in United States, Canada and Germany. J. William Langston's co-authors include Ian Irwin, James W. Tetrud, Philip L. Ballard, Lysia S. Forno, Donato A. Di Monte, Caroline M. Tanner, Louis E. DeLanney, Samuel M. Goldman, Raymond K. Mulhern and Larry E. Kun and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

J. William Langston

267 papers receiving 23.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

1983 3.6k citations J. William Langston, James W. Tetrud et al. profile →
Rotenone, Paraquat, and Parkinson’s Disease

2011 1.1k citations Caroline M. Tanner, Samuel M. Goldman et al. Environmental Health Perspectives profile →
Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

1999 743 citations J. William Langston, Lysia S. Forno et al. Annals of Neurology profile →
Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

1984 740 citations J. William Langston, Lysia S. Forno et al. profile →
Environmental Risk Factors and Parkinson's Disease: Selective Degeneration of Nigral Dopaminergic Neurons Caused by the Herbicide Paraquat

2002 602 citations Alison L. McCormack, J. William Langston et al. Neurobiology of Disease profile →
Comparison of kindreds with parkinsonism and α‐synuclein genomic multiplications

2004 531 citations Lysia S. Forno, J. William Langston et al. Annals of Neurology profile →
Pargyline Prevents MPTP-Induced Parkinsonism in Primates

1984 492 citations J. William Langston, Ian Irwin et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
J. William Langston United States	76	14.4k	9.7k	5.4k	3.2k	2.8k	268	24.4k
Lee J. Martin United States	76	5.3k 0.4×	8.7k 0.9×	9.0k 1.7×	3.2k 1.0×	4.3k 1.5×	242	21.6k
Andrew Singleton United States	73	10.7k 0.7×	5.4k 0.6×	8.2k 1.5×	4.3k 1.3×	4.8k 1.7×	334	21.9k
Albert C. Ludolph Germany	77	15.0k 1.0×	4.8k 0.5×	7.1k 1.3×	3.8k 1.2×	4.5k 1.6×	669	25.0k
Thomas Klockgether Germany	80	10.7k 0.7×	10.2k 1.0×	8.8k 1.6×	4.1k 1.3×	3.8k 1.4×	386	23.9k
M. Flint Beal United States	105	11.7k 0.8×	15.1k 1.6×	19.9k 3.7×	4.2k 1.3×	7.8k 2.8×	273	36.4k
Alexis Brice France	88	16.2k 1.1×	18.9k 1.9×	16.9k 3.1×	6.7k 2.1×	6.1k 2.2×	548	35.8k
Stanley Fahn United States	98	23.9k 1.7×	13.5k 1.4×	5.2k 1.0×	3.3k 1.0×	4.1k 1.5×	495	34.4k
Juan C. Troncoso United States	87	7.3k 0.5×	6.6k 0.7×	11.3k 2.1×	4.0k 1.3×	9.5k 3.4×	318	26.0k
Jeffrey D. Rothstein United States	91	12.4k 0.9×	15.0k 1.5×	15.7k 2.9×	8.2k 2.5×	5.0k 1.8×	235	37.2k
Neil W. Kowall United States	66	6.0k 0.4×	6.5k 0.7×	7.6k 1.4×	2.4k 0.7×	4.6k 1.6×	192	18.0k

Countries citing papers authored by J. William Langston

Since Specialization

Citations

This map shows the geographic impact of J. William Langston's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by J. William Langston with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites J. William Langston more than expected).

Fields of papers citing papers by J. William Langston

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by J. William Langston. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by J. William Langston. The network helps show where J. William Langston may publish in the future.

Co-authorship network of co-authors of J. William Langston

This figure shows the co-authorship network connecting the top 25 collaborators of J. William Langston. A scholar is included among the top collaborators of J. William Langston based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with J. William Langston. J. William Langston is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Christiansen, Michael, Joseph G. Hentz, Thomas G. Beach, et al.. (2017). Heart rate variability as a screening tool for Parkinson’s disease has age-dependent performance (P1.110). Neurology. 88(16_supplement). 1 indexed citations

Langston, J. William. (2017). The MPTP Story. Journal of Parkinson s Disease. 7(s1). S11–S19. 285 indexed citations

Goldman, Samuel M., Grace S. Bhudhikanok, Monica Korell, et al.. (2014). Heart Rate Variability in LRRK2 Parkinson’s Disease (S37.004). Neurology. 82(10_supplement). 1 indexed citations

Goldman, Samuel M., Sarah A. Jewell, Cheryl Meng, et al.. (2013). Parkinson's Disease Risk Is Associated with Variants in Genes That Bind Bacterial Cell-Wall Peptidoglycan (P05.051). Neurology. 80(7_supplement). 1 indexed citations

Sanders, Laurie H., Josée Laganière, Oliver Cooper, et al.. (2013). LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction. Neurobiology of Disease. 62. 381–386. 216 indexed citations

Quik, Maryka, et al.. (2009). Chronic Nicotine Treatment Increases nAChRs and Microglial Expression in Monkey Substantia Nigra After Nigrostriatal Damage. Journal of Molecular Neuroscience. 40(1-2). 105–113. 13 indexed citations

Quik, Maryka, Neeraja Parameswaran, Sarah E. McCallum, et al.. (2006). Chronic oral nicotine treatment protects against striatal degeneration in MPTP‐treated primates. Journal of Neurochemistry. 98(6). 1866–1875. 100 indexed citations

Tetrud, James W., et al.. (2006). Novel features in a patient homozygous for the L347P mutation in the PINK1 gene. Parkinsonism & Related Disorders. 13(6). 359–361. 11 indexed citations

Langston, J. William. (2005). Accelerating Research on Genes and Environment in Parkinson?s Disease. Environmental Health Perspectives. 1 indexed citations

10.

Togasaki, Daniel M., et al.. (2005). Enhanced striatal opioid receptor-mediated G-protein activation in l-dopa-treated dyskinetic monkeys. Neuroscience. 132(2). 409–420. 38 indexed citations

11.

Schlossmacher, Michael G., Matthew P. Frosch, Wei Gai, et al.. (2002). Parkin Localizes to the Lewy Bodies of Parkinson Disease and Dementia with Lewy Bodies. American Journal Of Pathology. 160(5). 1655–1667. 255 indexed citations

12.

Tan, Louis C.S., et al.. (2002). The hyperkinetic abnormal movements scale: A tool for measuring levodopa‐induced abnormal movements in squirrel monkeys. Movement Disorders. 17(5). 902–909. 17 indexed citations

13.

Shoulson, Ira, David Oakes, Stanley Fahn, et al.. (2002). Impact of sustained deprenyl (selegiline) in levodopa‐treated Parkinson's disease: A randomized placebo‐controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial. Annals of Neurology. 51(5). 604–612. 200 indexed citations

14.

Mahoney, Donald H., Michael E. Cohen, Henry S. Friedman, et al.. (2000). Carboplatin is effective therapy for young children with progressiveoptic pathway tumors: A Pediatric Oncology Group phase II study. Neuro-Oncology. 2(4). 213–220. 79 indexed citations

15.

Langston, J. William, et al.. (1999). Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Annals of Neurology. 46(4). 598–605. 743 indexed citations breakdown →

16.

Steen, R. Grant, Wilburn E. Reddick, Robert J. Ogg, & J. William Langston. (1999). Effect of a gadodiamide contrast agent on the reliability of brain tissue T1 measurements. Magnetic Resonance Imaging. 17(2). 229–235. 2 indexed citations

17.

Taylor, June S., Robert J. Ogg, & J. William Langston. (1998). PROTON MR SPECTROSCOPY OF PEDIATRIC BRAIN TUMORS. Neuroimaging Clinics of North America. 8(4). 753–779. 20 indexed citations

18.

Steen, R. Grant, Wilburn E. Reddick, Raymond K. Mulhern, et al.. (1998). Quantitative MRI of the brain in children with sickle cell disease reveals abnormalities unseen by conventional MRI. Journal of Magnetic Resonance Imaging. 8(3). 535–543. 54 indexed citations

19.

Monte, Donato A. Di, Ellen Y. Wu, Ian Irwin, Louis E. DeLanney, & J. William Langston. (1992). Production and disposition of 1‐methyl‐4‐phenylpyridinium in primary cultures of mouse astrocytes. Glia. 5(1). 48–55. 18 indexed citations

20.

Wilimas, Judith A., et al.. (1980). Efficacy of transfusion therapy for one to two years in patients with sickle cell disease and cerebrovascular accidents. The Journal of Pediatrics. 96(2). 205–208. 136 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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